Two-Years Follow-Up of Symptoms and Return to Work in Complex Post-COVID-19 Patients

Journal of Clinical Medicine, Journal Year: 2023, Volume and Issue: 12(3), P. 741 - 741

Published: Jan. 17, 2023

Introduction: Many COVID-19 patients present with severe long-lasting symptoms. They might benefit from a coordination team to manage such complex situations, but late efficacy still needs be determined. Population and Methods: Out of 105 contacts, 45 had two phone consultations separated by personalized support 15 22 months, respectively, after COVID infection. Self-reported symptoms, feelings improvement ability return work allowed us determine the therapeutic strategy proposed. Results: Unlike what was expected, many post-COVID-19 directly contacted significant pre-existing comorbidities. Despite exercise, respiratory, olfactory rehabilitations, cognition/speech therapy and/or psychological support, more frequent self-reported symptoms (fatigue, neurocognitive disorders, muscles joint pain) did not resolve. However, dyspnea, anxiety chest pain were significantly reduced. Finally, 2/3 felt some degree returned either partially or fully, 1/3 remained complaining out as months occurrence. All greatly appreciated second consultation. Conclusions: In besides early adapted rehabilitations help allowing better symptom management, relatively simple actions call very useful reduce patients’ abandonment.

Language: Английский

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Factors Influencing the Intention and Uptake of COVID-19 Vaccines on the African Continent: A Scoping Review

Vaccines, Journal Year: 2023, Volume and Issue: 11(4), P. 873 - 873

Published: April 20, 2023

The COVID-19 pandemic is a severe concern worldwide, particularly in Africa. Vaccines are crucial the fight against pandemic. This scoping review examined existing literature from 2020 to 2022 on individual, interpersonal, and structural barriers facilitators vaccination within Africa facilitate more informed health promotion interventions improve vaccine uptake. was conducted using Arksey O’Malley’s five-stage methodological framework. A comprehensive search undertaken 2021 six electronic databases: EBSCOhost, PubMed, Web of Science, ProQuest, WorldCat Discovery, Google Scholar. Data collected, charted into themes, summarized standard data extraction sheet Microsoft Excel. total forty (n = 40) published academic articles were reviewed, with many Nigeria 10), followed by Ethiopia 5) Ghana 4) rest elsewhere Thematic narratives used report themes: attitudes perceptions about vaccines, intention uptake vaccines; factors associated uptake; socio-demographic determinants affecting information sources for vaccines. ranged 25% 80.9%, resulting suboptimal rate (54.2%) African continent. Factors that promoted acceptance included confidence vaccines desire protect people. Age, education, gender most common significantly acceptance. Most studies revealed considerable exist Concerns potential side effects, ineffectiveness, perceived lack information, inaccessibility among unwillingness receive strongly correlated being female. Mass social media main regarding To encourage uptake, governments should pay attention refuting misinformation through integrated community-based approaches, such as creating messages convey than just information.

Language: Английский

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Upgrading Treatment and Molecular Diagnosis in Endometrial Cancer—Driving New Tools for Endometrial Preservation?

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(11), P. 9780 - 9780

Published: June 5, 2023

One emerging problem for onco-gynecologists is the incidence of premenopausal patients under 40 years age diagnosed with stage I Endometrial Cancer (EC) who want to preserve their fertility. Our review aims define a primary risk assessment that can help fertility experts and tailor personalized treatment fertility-preserving strategies fertile wishing have children. We confirm factors such as myometrial invasion The International Federation Gynecology Obstetrics (FIGO) staging should be integrated into novel molecular classification provided by Genome Atlas (TCGA). also corroborate influence classical obesity, Polycystic ovarian syndrome (PCOS), diabetes mellitus assess outcomes. preservation options are inadequately discussed women diagnosis gynecological cancer. A multidisciplinary team gynecologists, oncologists, specialists could increase patient satisfaction improve death rates endometrial cancer rising globally. guidelines recommend radical hysterectomy bilateral salpingo-oophorectomy standard care this cancer; however, fertility-sparing alternatives tailored motivated reproductive age, establishing an appropriate cost–benefit balance between childbearing desire risk. New classifications TCGA provide robust supplementary tool patient’s needs, curtail over- under-treatment, contribute spread strategies.

Language: Английский

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“GONE WITH THE WIND”: The Transitory Effects of COVID-19 on the Gynecological System

Journal of Personalized Medicine, Journal Year: 2023, Volume and Issue: 13(2), P. 312 - 312

Published: Feb. 10, 2023

The coronavirus disease no longer seems to represent an insurmountable global problem. This is thanks the advent of vaccines, which have alleviated most serious symptoms associated with this disease. On other hand, there are still many extrapulmonary COVID-19, and among these also those a gynecological nature. At moment, several questions in field, one above all concerns causal link between vaccines alterations. Furthermore, another important aspect represented by clinical impact post-COVID-19 alterations on female population which, date, would seem be mainly due their duration, even if extent poorly understood. it not possible foresee eventual long-term aggravations, or more caused viral variants that may arrive future. In review, we focus theme attempt reorganize different pieces puzzle does shown us its complete picture.

Language: Английский

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The Pandemic and Your Skin—Direct and Indirect Impact of COVID-19

Cosmetics, Journal Year: 2023, Volume and Issue: 10(1), P. 34 - 34

Published: Feb. 15, 2023

Apart from well-known respiratory symptoms, less frequent symptoms also appear as a direct result of COVID-19 infection, or indirect effects the recommended quarantine and related lifestyle changes. The impact pandemic on human skin is predominantly focused in this article. Cutaneous manifestations, including redness, chilblain-like (COVID toes), hives urticaria rash, water blisters, fishing net-like red-blue patterns skin, may accompanying systemic with potential lesions at different sites. These were to phototypes vitamin D deficiency. Moreover, Black, Asian, minority ethnic origin patients are found be more sensitive infection than Caucasians because region population lighter have significantly higher chance develop cutaneous manifestations dark skin. In addition, adverse effects, such barrier damage irritation, occur due extensive personal protective equipment usage (e.g., masks, suits, few others) predominately alcohol-based sanitizers. This manuscript covers various aspects its clinical manifestations.

Language: Английский

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Hormone replacement therapy in BRCA mutation carriers: how shall we do no harm?

HORMONES, Journal Year: 2023, Volume and Issue: 22(1), P. 19 - 23

Published: Jan. 13, 2023

Language: Английский

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The Role of Diet and Specific Nutrients during the COVID-19 Pandemic: What Have We Learned over the Last Three Years?

International Journal of Environmental Research and Public Health, Journal Year: 2023, Volume and Issue: 20(7), P. 5400 - 5400

Published: April 4, 2023

Nutrients and diets have an important impact on our immune system infection risk a huge number of papers been published dealing with various aspects nutrition in relation to SARS-CoV-2 or COVID-19 severity. This narrative review aims give update this association tries summarize some the most findings after three years pandemic. The analysis major studies systematic reviews leads conclusion that healthy plant-based diet reduces risks for especially Regarding micronutrients, vitamin D is fore, but also zinc, C and, extent, selenium may play role COVID-19. Furthermore, omega-3-fatty acids their anti-inflammatory effects deserve attention. Therefore, aim societal nutritional efforts future should be foster high quality diet, which not only exerts beneficial non-communicable diseases such as type 2 diabetes obesity are primary factors worse outcomes. Another focus good supply critical immune-effective nutrients, zinc.

Language: Английский

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Effect of dietary restriction on health span in Caenorhabditis elegans: A systematic review

Experimental Gerontology, Journal Year: 2023, Volume and Issue: 182, P. 112294 - 112294

Published: Sept. 26, 2023

Dietary restriction (DR) interventions have demonstrated their efficacy in extending lifespan; however, the association between lifespan extension and health span remains unclear. This article aims to analyze relationship DR-induced Caenorhabditis elegans (C. elegans), a widely used animal model studies. By examining various parameters such as lipofuscin accumulation (an aging marker) locomotor feeding capacities (indicators of muscle degradation rate), we compiled papers that investigate report on these effects.The majority reviewed consistently demonstrate DR improves both C. elegans. Worms subjected exhibit slower compared those fed ad libitum, indicating reduction age-related cellular damage. Additionally, DR-treated worms display higher locomotion capacity, suggesting rate degradation. However, it is worth noting there are some discrepancies among regarding capacity. These contradictions can be attributed different methods employed initiate DR. While many approaches slow degeneration enhance pumping rates through adaptation limited food sources, other methods, using eat-2 mutant or mimic effects eat-2, reduce capacity consequently restrict intake. In conclusion, findings suggest strong correlation longevity elegans, evidenced by improvements parameters. not only extend but also mitigate markers preserve Although conflicting results observed overall evidence supports notion promotes healthier this model.

Language: Английский

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Intrapartum ultrasound and mother acceptance: A study with informed consent and questionnaire

European Journal of Obstetrics & Gynecology and Reproductive Biology X, Journal Year: 2023, Volume and Issue: 20, P. 100246 - 100246

Published: Oct. 11, 2023

Intrapartum ultrasound (IU) is used in the delivery ward; even if IU monitors labouring women, it could be perceived as a discomfort and an" obstetric violence", because young technique, not often well "accepted". A group of clinicians aimed at obtain an informed consent from patients, prior to perform translabial (TU). The aim this study was evaluate acceptance both transabdominal IU.In study, performed University Hospital Bari (Unit Obstetrics Gynecology), were enrolled 103 patients first or second stage labor singleton cephalic presentation. statistical frequency association analysis performed. As significant result, we consider peace mind/satisfaction the" violence". determine presentation, head positions, angle progression perineum distance. During labor, ASIUG questionnaires (Apulia intrapartum ultrasonography group) administered.74 (71, 84%) underwent 29 had vaginal examination (28, 15%). Significant less "violence" has been experienced with (73 out 74/98, 65%) only one person (1 /1, 35%) recorded that. On contrary, 10 (10/29) that (34, 48%) while 19 (65, 52%) did respond on similar way, after (VE). More felt satisfaction (71 74/95, 95%) use 3 (3/4, 05%) unease. different picture evident group. Only 17 (17 29/58, 62%) comfort 12 (41, 38%) unease.In our accepted by most reassure women about their fetal condition. Moreover, they can see fetus screen, obstetrician performing US important for visual feedback, comparison classical VE.

Language: Английский

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“Lights and Shades” of Fertility Preservation in Transgender Men Patients: A Clinical and Pathological Review

Life, Journal Year: 2023, Volume and Issue: 13(6), P. 1312 - 1312

Published: June 1, 2023

Fertility preservation (FP) is becoming a critical issue in transgender men who desire biological offspring the future. The prevalence of individuals United States increasing, and as result, demand for gender-affirming surgeries (GAS) associated FP techniques rising. Despite growing demand, there currently no personalized approach to men, available have limitations that require further investigation. In present review we carefully examine existing literature on this topic highlight shortcomings current methods areas where additional research needed advance field. Hormonal therapy (HT), which an integral part gender transition can significant impact fertility may increase risk various diseases. Moreover, GAS usually leads permanent sterility these patients. Therefore, it essential provide patients with accurate information about benefits potential risks different techniques, taking into account patient’s reproductive goals. This underscores complex multifaceted nature emphasizes need develop more effective approaches population.

Language: Английский

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