Experimental Gerontology,
Journal Year:
2024,
Volume and Issue:
199, P. 112660 - 112660
Published: Dec. 19, 2024
Skin
aging,
often
called
as
premature
skin
is
the
hastened
deterioration
of
resulting
from
multiple
factors,
including
UV
radiation,
environmental
contaminants,
inadequate
nutrition,
stress,
etc.
Dietary
phytochemicals,
present
in
fruits,
vegetables,
and
other
plant-derived
meals,
have
gained
interest
due
to
their
efficiency
eradicate
free
radicals
lowering
release
inflammatory
mediators
which
accounts
for
aging.
Several
dietary
i.e.,
carotenoids,
polyphenols,
flavonoids,
terpenes,
alkaloids,
phytosterols,
etc.,
exhibited
potential
anti-oxidant,
anti-inflammatory,
suppression
damage,
promote
collagen
synthesis.
In
addition,
phytochemicals
include
sulfur,
various
foods
safeguard
against
oxidative
stress
inflammation.
Thus,
this
article
delves
into
comprehension
investigated
alleviate
The
further
highlights
specific
sources,
bioavailability,
mechanisms,
context
safeguarding
manuscript
a
systematic
available
literature
on
aging
database,
PubMed,
ScienceDirect,
Google
Scholar
using
keywords,
"dietary
phytochemicals",
"nutraceuticals",
"skin
aging"
via
Boolean
operator,
"AND".
guidelines
presented
unique
summarization
broad
reader
understand
inclusion
functional
foods,
nutrients,
supplements,
prevent
utilization
has
shown
promising
avenue
preventing
however,
future
perspectives
challenges
such
should
be
comprehended
clinical
investigations.
Foods,
Journal Year:
2025,
Volume and Issue:
14(3), P. 347 - 347
Published: Jan. 21, 2025
Bee
pollen
is
characterized
by
an
exceptional
diversity
and
abundance
of
micronutrients
bioactive
phytochemicals.
This
richness
remains
very
sparsely
investigated,
but
accumulating
evidence
strongly
supports
a
promising
future
for
bee
in
human
nutrition
medicine.
Epigenetic
regulation
among
the
most
compelling
biomedical
topics
that
remain
completely
untapped
derivative
research.
In
our
current
research,
we
identified
numerous
ubiquitous
compounds
are
consistently
present
this
matrix,
regardless
its
botanical
geographical
origins,
have
been
well
studied
documented
as
epigenetic
regulators
recent
years.
Given
relative
newness
both
research
studies
within
nutritional,
pharmaceutical,
medical
sciences,
review
aims
to
bridge
these
valuable
fields
advance
related
experimental
investigations.
To
best
knowledge,
first
work
has
aimed
comprehensively
investigate
modulatory
potential
compounds.
Our
findings
also
unveiled
several
intriguing
phenomena,
such
dual
effect
same
compound
depending
on
cellular
context
or
some
cross-generational
heritability
traits.
Although
whole
extract
still
lacking,
study
clearly
indicates
avenue
worth
further
We
hope
constitutes
foundational
cornerstone
investigations
Marine Drugs,
Journal Year:
2023,
Volume and Issue:
21(6), P. 323 - 323
Published: May 26, 2023
Polyphenols
are
compounds
found
in
various
plants
and
foods,
known
for
their
antioxidant
anti-inflammatory
properties.
Recently,
researchers
have
been
exploring
the
therapeutic
potential
of
marine
polyphenols
other
minor
nutrients
that
algae,
fish
crustaceans.
These
unique
chemical
structures
exhibit
diverse
biological
properties,
including
anti-inflammatory,
antioxidant,
antimicrobial
antitumor
action.
Due
to
these
being
investigated
as
possible
agents
treatment
a
wide
variety
conditions,
such
cardiovascular
disease,
diabetes,
neurodegenerative
diseases
cancer.
This
review
focuses
on
applications
human
health,
also,
phenolic
classes,
extraction
methods,
purification
techniques
future
compounds.
Antioxidants,
Journal Year:
2023,
Volume and Issue:
12(12), P. 2086 - 2086
Published: Dec. 7, 2023
The
ends
of
human
chromosomes
are
defended
by
DNA-protein
complexes
named
telomeres,
which
inhibit
the
from
fusing
with
each
other
and
being
known
as
a
double-strand
break
DNA
reparation
proteins.
Telomere
length
is
marker
biological
aging,
disfunction
telomeres
related
to
age-related
syndromes.
attrition
has
been
shown
be
accelerated
oxidative
stress
inflammation.
proven
positively
linked
nutritional
status
in
animal
scientific
research
several
nutrients
influence
it
through
mechanisms
that
imitate
their
function
cellular
roles
including
Data
reported
this
article
support
idea
following
low-in-fat
rich-plant
polyphenols
food
diet
seems
able
slow
down
shortening
telomeres.
Advances in Nutrition,
Journal Year:
2023,
Volume and Issue:
14(5), P. 1111 - 1130
Published: June 2, 2023
Cellular
senescence
has
long
been
considered
a
permanent
state
of
cell
cycle
arrest
occurring
in
proliferating
cells
subject
to
different
stressors,
used
as
cellular
defense
mechanism
from
acquiring
potentially
harmful
genetic
faults.
However,
recent
studies
highlight
that
senescent
might
also
alter
the
local
tissue
environment
and
concur
chronic
inflammation
cancer
risk
by
secreting
inflammatory
matrix
remodeling
factors,
senescence-associated
secretory
phenotype
(SASP).
Indeed,
during
aging
age-related
diseases,
amass
mammalian
tissues,
likely
contributing
inevitable
loss
function
we
age.
thus
become
one
potential
target
tackle
age-associated
diseases
well
development.
One
important
aspect
characterizing
is
their
telomere
length.
Telomeres
shorten
consequence
multiple
replications,
gradually
leading
arrest,
known
replicative
senescence.
Interestingly,
large
majority
cells,
escape
strategy
length
maintained
telomerase,
favoring
initiation
tumor
survival.
There
growing
evidence
showing
how
(poly)phenols
can
impact
maintenance
through
molecular
mechanisms
depending
on
dose
phenotypes.
Although
normally,
maintain
support
telomerase
activity,
this
activity
negatively
modulated,
accelerating
attrition
promoting
death.
Some
have
shown
exert
senolytic
suggesting
both
antiaging
(directly
eliminating
cells)
anticancer
(indirectly,
via
SASP
inhibition)
potentials.
In
review,
analyze
selective
(poly)phenol
discriminate
between
vitro
vivo
human
applications
considering
bioavailability,
influence
gut
microbiota,
dose-response
effects.
