A Review of the Antibacterial, Fungicidal and Antiviral Properties of Selenium Nanoparticles

Materials, Journal Year: 2023, Volume and Issue: 16(15), P. 5363 - 5363

Published: July 30, 2023

The resistance of microorganisms to antimicrobial drugs is an important problem worldwide. To solve this problem, active searches for components, approaches and therapies are being carried out. Selenium nanoparticles have high potential activity. relevance their application indisputable, which can be noted due the significant increase in publications on topic over past decade. This review research aims provide reader with up-to-date information properties selenium nanoparticles, including susceptible microorganisms, mechanisms action bacteria effect nanoparticle describes most complete antiviral, antibacterial antifungal effects nanoparticles.

Language: Английский

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Roles of selenium-containing glutathione peroxidases and thioredoxin reductases in the regulation of processes associated with glioblastoma progression

Archives of Biochemistry and Biophysics, Journal Year: 2025, Volume and Issue: unknown, P. 110344 - 110344

Published: Feb. 1, 2025

Language: Английский

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Selenium-containing compounds, selenium nanoparticles and selenoproteins in the prevention and treatment of lung cancer

Journal of Trace Elements in Medicine and Biology, Journal Year: 2025, Volume and Issue: 88, P. 127620 - 127620

Published: Feb. 14, 2025

Language: Английский

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Screening, characterization, and potential anti-hangover ability of selenium nanoparticle-enriched lactobacillus

International Microbiology, Journal Year: 2025, Volume and Issue: unknown

Published: March 28, 2025

Language: Английский

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Selenium, Silver, and Gold Nanoparticles: Emerging Strategies for Hepatic Oxidative Stress and Inflammation Reduction

Nano TransMed, Journal Year: 2025, Volume and Issue: unknown, P. 100085 - 100085

Published: May 1, 2025

Language: Английский

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Starch-Stabilized Selenium Nanoparticles: Synthesis, Purification, Characterization, In Vitro Anticancer and Apoptosis Inducing Evaluation

BioNanoScience, Journal Year: 2024, Volume and Issue: 14(2), P. 1545 - 1560

Published: Jan. 15, 2024

Language: Английский

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Synthesis, characterization and MAFLD prevention potential of Ganoderma lucidum spore polysaccharide-stabilized selenium nanoparticles

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 282, P. 136962 - 136962

Published: Oct. 28, 2024

Language: Английский

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Antifibrotic Effect of Selenium-Containing Nanoparticles on a Model of TAA-Induced Liver Fibrosis

Cells, Journal Year: 2023, Volume and Issue: 12(23), P. 2723 - 2723

Published: Nov. 28, 2023

For the first time, based on expression analysis of a wide range pro- and anti-fibrotic, anti-inflammatory, anti-apoptotic genes, key markers endoplasmic reticulum stress (ER-stress), molecular mechanisms for regulation fibrosis, accompanying negative processes caused by thioacetamide (TAA) injections subsequent selenium-containing nanoparticles sorafenib have been proposed. We found that selenium two types (doped with without sorafenib) led to significant decrease in almost all pro-fibrotic pro-inflammatory genes. Sorafenib also reduced mRNA genes but less effectively than both nanoparticles. In addition, it was shown time TAA can be an inducer ER-stress, most likely activating IRE1α PERK signaling pathways UPR, apoptosis pyroptosis. Sorafenib, despite pronounced effect, still did not reduce caspase-3 12 or mitogen-activated kinase JNK1 control values, which increases risk persistent liver cells. After nanoparticles, effects were leveled, causing adaptive UPR response through activation pathway. The advantages over sorafenib, established this work, once again emphasize unique properties microelement serve as important factor further introduction drugs into clinical practice.

Language: Английский

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Nano-Formulations of Natural Antioxidants for the Treatment of Liver Cancer

Biomolecules, Journal Year: 2024, Volume and Issue: 14(8), P. 1031 - 1031

Published: Aug. 19, 2024

Oxidative stress is a key factor in the pathological processes that trigger various chronic liver diseases, and significantly contributes to development of hepatocarcinogenesis. Natural antioxidants reduce oxidative by neutralizing free radicals play crucial role treatment free-radical-induced diseases. However, their efficacy often limited poor bioavailability metabolic stability. To address these limitations, recent advances have focused on developing nano-drug delivery systems protect them from degradation enhance therapeutic potential. Among several critical benefits, they showed be able improve targeted delivery, thereby reducing off-target effects specifically directing antioxidant tumor site. Moreover, nanosystems led sustained release, prolonging effect over time. Some also exhibited synergistic when combined with other agents, allowing for improved overall efficacy. This review aims discuss scientific nano-formulations containing natural molecules, highlighting potential as promising approaches cancer. The novelty this lies its comprehensive focus latest developments

Language: Английский

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Chitosan-encapsulated selenium nanoparticles alleviate CCl4 induced hepatotoxicity through synergistically modulating NF-κB and Nrf2 signaling pathways and regulating Bcl-2 and Caspase-3 expression: A comprehensive study with multiple regression analysis

Journal of Trace Elements in Medicine and Biology, Journal Year: 2024, Volume and Issue: 86, P. 127563 - 127563

Published: Nov. 10, 2024

Language: Английский

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