Chemistry & Biodiversity,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 23, 2024
ABSTRACT
This
study
investigated
the
chemical
composition
of
essential
oil
from
Tetrapanax
papyrifer
and
evaluated
its
antioxidant
anti‐α‐glucosidase
activity.
A
total
61
compounds
T.
were
identified
by
gas
chromatography‐mass
spectrometry
(GC‐MS)
chromatography‐flame
ionization
detector
(GC‐FID).
The
is
rich
in
sesquiterpenoids
(96.05%),
with
major
components
as
β‐cubebene
(13.96%),
caryophyllene
(13.43%),
α‐cubebene
(12.12%),
copaene
(7.89%),
δ
‐cadinene
(7.29%),
eremophilene
(6.15%),
humulene
(5.26%).
showed
dose‐dependent
activity
IC
50
values
723.15
±
24.10
200.74
9.90
µg/mL
for
2,2‐diphenyl‐1‐picrylhydrazyl
(DPPH)
2,2'‐azino‐bis(3‐ethylbenzothiazoline‐6‐sulfonic
acid)
(ABTS)
assays,
respectively.
Ferric
reducing
power
(FRAP)
capacity
was
222.73
25.49
µmol/g.
exhibited
a
17.86%
0.56%
inhibitory
effect
against
α‐glucosidase
at
500
µg/mL.
Moreover,
silico
molecular
docking
analyses
utilized
to
validate
vitro
results
further.
Frontiers in Medicine,
Journal Year:
2024,
Volume and Issue:
11
Published: Feb. 16, 2024
Essential
oils
from
various
plants
have
diverse
therapeutic
properties
and
are
researched
extensively.
They
applications
in
medicine,
aromatherapy,
microbiology,
agriculture,
livestock,
the
food
industry,
benefiting
population.
Food Chemistry X,
Journal Year:
2024,
Volume and Issue:
22, P. 101521 - 101521
Published: May 28, 2024
Lemongrass
essential
oil
(LEO),
extracted
from
high-oil
lemongrass,
gains
prominence
as
a
versatile
natural
product
due
to
growing
demand
for
safe
health
solutions.
LEO
comprises
beneficial
compounds
like
citral,
isoneral,
geraniol,
and
citronellal,
offering
diverse
pharmacological
benefits
such
antioxidant,
antifungal,
antibacterial,
antiviral,
anticancer
effects.
finds
applications
in
food
preservation,
cosmetics,
pharmaceuticals,
enhancing
profitability
across
these
sectors.
The
review
focuses
on
the
extraction
of
LEO,
emphasizing
need
cost-effective
methods.
Ultrasound
supercritical
fluid
are
effective
reducing
time,
increasing
yields,
quality.
shows
promise
valuable
resource
industries,
with
packaging,
coating,
film
development.
LEO's
ability
extend
shelf
life
items
impart
flavors
positions
it
asset.
Overall,
emphasizes
therapeutic,
antimicrobial,
antioxidant
properties,
strengthening
its
potential
food,
pharmaceutical,
cosmetic
Foods,
Journal Year:
2025,
Volume and Issue:
14(7), P. 1182 - 1182
Published: March 28, 2025
Sage
and
peppermint
leaves
flowers
possess
antioxidant,
anti-inflammatory,
metabolic-regulating
properties.
This
study
compared
the
phenolic
profiles
confirmed
using
LC-MS/MS
analysis
biological
activities
of
traditionally
prepared
sage
(SJ)
juices
(PJ),
evaluating
their
ex
vivo
antioxidant
enzyme
activity
antidiabetic
potential
in
experimental
mice.
Quinic
acid
(2571.86
±
1.15
µg/g
dry
weight
(d.w.))
apigenin-7-O-β-glucoside
(324.36
d.w.)
were
predominant
compounds
SJ,
while
PJ
contained
caffeic
(16.96
0.12
quinic
(184.27
0.45
d.w.).
The
administration
SJ
for
ten
days
significantly
reduced
blood
glucose
levels
Compared
to
control
group,
which
showed
an
increase
from
15.89
3.45
29.54
8.94
mmoL/L,
SJ-20
mg/kg
body
(BW)-treated
mice
exhibited
a
more
moderate
rise
(16.25
7.33
21.50
10.38
mmoL/L).
Juice
also
enhanced
activity,
with
PJ-20
BW
increasing
superoxide
dismutase
(SOD)
(30.15
3.99
U/mg
proteins)
(18.83
2.04
proteins).
Additionally,
catalase
(CAT)
was
elevated,
indicating
oxidative
stress
defense
mechanisms.
Furthermore,
treatment
aspartate
aminotransferase
(AST)
(7025.8
1038.8
2782
426.9
IU/L)
alanine
(ALT)
(10679
1409.2
5336.5
801.5
IU/L),
suggesting
hepatoprotective
effects.
These
results
support
traditional
use
as
functional
beverages
antidiabetic,
properties,
warranting
further
clinical
investigation.
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(2), P. 1252 - 1252
Published: Jan. 19, 2024
Glucose
transporter-4
(GLUT4)
represents
the
major
glucose
transporter
isoform
responsible
for
uptake
into
insulin-sensitive
cells,
primarily
in
skeletal
muscle
and
adipose
tissues.
In
insulin-resistant
conditions,
such
as
type
2
diabetes
mellitus,
GLUT4
expression
and/or
translocation
to
cell
plasma
membrane
is
reduced,
compromising
energy
metabolism.
Therefore,
use
of
synthetic
or
naturally
occurring
molecules
able
stimulate
a
good
tool
alternative
treatments
insulin
resistance.
The
present
study
aimed
investigate
effects
essential
oils
(EOs)
derived
from
Pinus
spp.
(P.
nigra
P.
radiata)
their
main
terpenoid
constituents
(α-
β-pinene)
on
expression/translocation
myoblast
C2C12
murine
cells.
For
this
purpose,
chemical
profiles
EOs
were
first
analyzed
through
gas
chromatography-mass
spectrometry
(GC-MS).
Cell
viability
was
assessed
by
MTT
assay,
evaluated
RT-qPCR
flow
cytometry
analyses.
results
showed
that
only
oil
(PnEO)
α-pinene
can
increase
transcription
Glut4/Scl2a4
gene,
resulting
subsequent
amount
produced
its
localization.
Moreover,
PnEO
induce
Glut4
both
during
myogenesis
myotubes.
summary,
emulate
insulin's
effect
surface.
Molecules,
Journal Year:
2024,
Volume and Issue:
29(12), P. 2720 - 2720
Published: June 7, 2024
The
present
study
provides
a
comprehensive
analysis
of
the
chemical
composition
essential
oils
from
species
Myrcia
genus
and
their
applications.
compiled
results
highlight
diversity
biological
activities
these
oils,
emphasizing
potential
importance
for
various
therapeutic
industrial
findings
reveal
that
variety
bioactive
compounds,
such
as
monoterpenes
sesquiterpenes,
which
demonstrate
antimicrobial
against
range
microorganisms,
including
Gram-positive
Gram-negative
bacteria,
well
yeasts.
Furthermore,
this
highlights
phytotoxic
activity
indicating
weed
control.
also
point
to
insecticidal
pests,
showing
viability
an
alternative
synthetic
pesticides.
Additionally,
have
demonstrated
promising
hypoglycemic
effects,
suggesting
in
diabetes
treatment.
This
synthesis
represents
significant
advancement
understanding
highlighting
wide
activities.
However,
need
further
research
is
emphasized
fully
explore
identification
new
mechanisms
action,
evaluation
safety
efficacy
different
contexts.
Natural Product Communications,
Journal Year:
2024,
Volume and Issue:
19(4)
Published: April 1, 2024
Nonalcoholic
fatty
liver
disease
(NAFLD),
characterized
by
excessive
fat
accumulation,
is
a
common
linked
to
obesity,
insulin
resistance,
and
metabolic
dysfunction.
The
lack
of
effective
treatments
against
NAFLD
has
led
an
increasing
focus
on
alternative
natural
remedies.
Essential
oils,
extracted
from
variety
plants,
have
drawn
interest
due
their
high
content
active
compounds
potential
functions
support
health.
Ginger
essential
oil,
known
for
its
anti-inflammatory,
antioxidant,
cholesterol-lowering
properties,
promotes
antioxidant
enzymes
ameliorates
accumulation
in
mice
model
NAFLD.
Nigella
sativa
oil
with
diverse
array
bioactive
components,
mitigates
lowering
tumor
necrosis
factor-alpha,
malonaldehyde
(MDA),
plasma
lipids
vivo
human
trials
that
could
contribute
management.
Garlic
rich
organosulfur
compounds,
shown
benefits
modulating
oxidative
stress
inflammation
associated
Similarly,
oils
turmeric,
pepper,
patchouli,
basil
reduced
lipid
enhanced
metabolism
animal
models
These
findings
underscore
the
use
as
complementary
medicines
NAFLD,
opening
avenues
further
research
clinical
applications.
Plants,
Journal Year:
2024,
Volume and Issue:
13(11), P. 1436 - 1436
Published: May 22, 2024
Diabetes
mellitus
(DM)
is
a
global
health
concern
characterized
by
deficiency
in
insulin
production.
Considering
the
systemic
toxicity
and
limited
efficacy
associated
with
current
antidiabetic
medications,
there
utmost
need
for
natural,
plant-based
alternatives.
Herbal
medicines
have
experienced
exponential
growth
popularity
globally
recent
years
their
natural
origins
minimal
side
effects.
Ecuador
has
rich
cultural
history
ethnobotany
that
plays
crucial
role
its
people’s
lives.
This
study
identifies
27
Ecuadorian
medicinal
plants
are
traditionally
used
diabetes
treatment
prepared
through
infusion,
decoction,
or
juice,
ingested
raw
forms.
Among
them,
22
demonstrated
hypoglycemic
anti-hyperglycemic
properties
bioactive
phytochemicals,
which
was
confirmed
several
vitro
vivo
studies.
However,
Bryophyllum
gastonis-bonnieri,
Costus
villosissimus,
Juglans
neotropica,
Pithecellobium
excelsum,
Myroxylon
peruiferum,
were
extensively
traditional
medicine
preparation
many
decades
to
treat
diabetes,
lacking
pharmacological
elucidation.
The
been
found
compounds
such
as
flavonoids,
phenolics,
fatty
acids,
aldehydes,
terpenoids
mainly
responsible
reducing
blood
sugar
levels
oxidative
stress,
regulating
intestinal
function,
improving
resistance,
inhibiting
α-amylase
α-glucosidase,
lowering
gluconeogenic
enzymes,
stimulating
glucose
uptake
mechanisms,
playing
an
important
lipid
metabolism.
substantial
lack
of
integrated
approaches
between
existing
ethnomedicinal
practices
research.
Therefore,
this
review
aims
discuss
explore
treating
DM
properties.
We
believe
use
herbal
scientifically
sound
way
can
substantially
benefit
local
economy
industries
seeking
products.