Essential Oil from Tetrapanax papyrifer (Hook.) K. Koch: Chemical Composition, Antioxidant Activity, α‐Glucosidase Inhibitory Effect Integrating Molecular Docking Analysis DOI Open Access
Ziyue Xu, Jiadong Zhu, Peizhong Gao

et al.

Chemistry & Biodiversity, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 23, 2024

ABSTRACT This study investigated the chemical composition of essential oil from Tetrapanax papyrifer and evaluated its antioxidant anti‐α‐glucosidase activity. A total 61 compounds T. were identified by gas chromatography‐mass spectrometry (GC‐MS) chromatography‐flame ionization detector (GC‐FID). The is rich in sesquiterpenoids (96.05%), with major components as β‐cubebene (13.96%), caryophyllene (13.43%), α‐cubebene (12.12%), copaene (7.89%), δ ‐cadinene (7.29%), eremophilene (6.15%), humulene (5.26%). showed dose‐dependent activity IC 50 values 723.15 ± 24.10 200.74 9.90 µg/mL for 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) 2,2'‐azino‐bis(3‐ethylbenzothiazoline‐6‐sulfonic acid) (ABTS) assays, respectively. Ferric reducing power (FRAP) capacity was 222.73 25.49 µmol/g. exhibited a 17.86% 0.56% inhibitory effect against α‐glucosidase at 500 µg/mL. Moreover, silico molecular docking analyses utilized to validate vitro results further.

Language: Английский

Essential oils: a systematic review on revolutionizing health, nutrition, and omics for optimal well-being DOI Creative Commons

Camila Pezantes-Orellana,

F.. Bermudez,

Carmen Matías De la Cruz

et al.

Frontiers in Medicine, Journal Year: 2024, Volume and Issue: 11

Published: Feb. 16, 2024

Essential oils from various plants have diverse therapeutic properties and are researched extensively. They applications in medicine, aromatherapy, microbiology, agriculture, livestock, the food industry, benefiting population.

Language: Английский

Citations

30

Insights into chemistry, extraction and industrial application of lemon grass essential oil -A review of recent advances DOI Creative Commons

Barjees Ashaq,

Khansa Rasool,

Samira Habib

et al.

Food Chemistry X, Journal Year: 2024, Volume and Issue: 22, P. 101521 - 101521

Published: May 28, 2024

Lemongrass essential oil (LEO), extracted from high-oil lemongrass, gains prominence as a versatile natural product due to growing demand for safe health solutions. LEO comprises beneficial compounds like citral, isoneral, geraniol, and citronellal, offering diverse pharmacological benefits such antioxidant, antifungal, antibacterial, antiviral, anticancer effects. finds applications in food preservation, cosmetics, pharmaceuticals, enhancing profitability across these sectors. The review focuses on the extraction of LEO, emphasizing need cost-effective methods. Ultrasound supercritical fluid are effective reducing time, increasing yields, quality. shows promise valuable resource industries, with packaging, coating, film development. LEO's ability extend shelf life items impart flavors positions it asset. Overall, emphasizes therapeutic, antimicrobial, antioxidant properties, strengthening its potential food, pharmaceutical, cosmetic

Language: Английский

Citations

10

Chemical compositions and enzyme inhibitory activities of the essential oils of Amomum putrescens D. Fang from Vietnam DOI
Van Trung Hoang, Hieu Tran-Trung, Danh C. Vu

et al.

Journal of Essential Oil Bearing Plants, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 7

Published: Jan. 13, 2025

Language: Английский

Citations

0

Assessing antioxidant potential and α-amylase inhibitory activity of essential oil from Neolitsea bidoupensis leaves DOI
Trần Thị Thanh Huyền, Danh C. Vu, Van Thu Nguyen

et al.

Journal of Essential Oil Bearing Plants, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 9

Published: March 12, 2025

Language: Английский

Citations

0

Health Benefits of Traditional Sage and Peppermint Juices: Simple Solutions for Antioxidant and Antidiabetic Support DOI Creative Commons
Sanja Vlaisavljević,

Isidora Milanović,

Nebojša Stilinović

et al.

Foods, Journal Year: 2025, Volume and Issue: 14(7), P. 1182 - 1182

Published: March 28, 2025

Sage and peppermint leaves flowers possess antioxidant, anti-inflammatory, metabolic-regulating properties. This study compared the phenolic profiles confirmed using LC-MS/MS analysis biological activities of traditionally prepared sage (SJ) juices (PJ), evaluating their ex vivo antioxidant enzyme activity antidiabetic potential in experimental mice. Quinic acid (2571.86 ± 1.15 µg/g dry weight (d.w.)) apigenin-7-O-β-glucoside (324.36 d.w.) were predominant compounds SJ, while PJ contained caffeic (16.96 0.12 quinic (184.27 0.45 d.w.). The administration SJ for ten days significantly reduced blood glucose levels Compared to control group, which showed an increase from 15.89 3.45 29.54 8.94 mmoL/L, SJ-20 mg/kg body (BW)-treated mice exhibited a more moderate rise (16.25 7.33 21.50 10.38 mmoL/L). Juice also enhanced activity, with PJ-20 BW increasing superoxide dismutase (SOD) (30.15 3.99 U/mg proteins) (18.83 2.04 proteins). Additionally, catalase (CAT) was elevated, indicating oxidative stress defense mechanisms. Furthermore, treatment aspartate aminotransferase (AST) (7025.8 1038.8 2782 426.9 IU/L) alanine (ALT) (10679 1409.2 5336.5 801.5 IU/L), suggesting hepatoprotective effects. These results support traditional use as functional beverages antidiabetic, properties, warranting further clinical investigation.

Language: Английский

Citations

0

In silico molecular docking and in (vivo/vitro) biological studies of various bioactive compounds of essential oil-bearing plants: A review DOI
Monika Rana, Meenakshi Rana

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 215 - 225

Published: Jan. 1, 2025

Language: Английский

Citations

0

α-Pinene, a Main Component of Pinus Essential Oils, Enhances the Expression of Insulin-Sensitive Glucose Transporter Type 4 in Murine Skeletal Muscle Cells DOI Open Access
Giordana Feriotto,

Federico Tagliati,

Valentina Costa

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(2), P. 1252 - 1252

Published: Jan. 19, 2024

Glucose transporter-4 (GLUT4) represents the major glucose transporter isoform responsible for uptake into insulin-sensitive cells, primarily in skeletal muscle and adipose tissues. In insulin-resistant conditions, such as type 2 diabetes mellitus, GLUT4 expression and/or translocation to cell plasma membrane is reduced, compromising energy metabolism. Therefore, use of synthetic or naturally occurring molecules able stimulate a good tool alternative treatments insulin resistance. The present study aimed investigate effects essential oils (EOs) derived from Pinus spp. (P. nigra P. radiata) their main terpenoid constituents (α- β-pinene) on expression/translocation myoblast C2C12 murine cells. For this purpose, chemical profiles EOs were first analyzed through gas chromatography-mass spectrometry (GC-MS). Cell viability was assessed by MTT assay, evaluated RT-qPCR flow cytometry analyses. results showed that only oil (PnEO) α-pinene can increase transcription Glut4/Scl2a4 gene, resulting subsequent amount produced its localization. Moreover, PnEO induce Glut4 both during myogenesis myotubes. summary, emulate insulin's effect surface.

Language: Английский

Citations

3

Exploring the Potential of Myrcia Genus Essential Oils: A Review of Biological Activities and Recent Advances DOI Creative Commons

Eliza de Jesus Barros dos Santos,

Fernanda Wariss Figueiredo Bezerra,

Luiz Renan Ramos da Silva

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(12), P. 2720 - 2720

Published: June 7, 2024

The present study provides a comprehensive analysis of the chemical composition essential oils from species Myrcia genus and their applications. compiled results highlight diversity biological activities these oils, emphasizing potential importance for various therapeutic industrial findings reveal that variety bioactive compounds, such as monoterpenes sesquiterpenes, which demonstrate antimicrobial against range microorganisms, including Gram-positive Gram-negative bacteria, well yeasts. Furthermore, this highlights phytotoxic activity indicating weed control. also point to insecticidal pests, showing viability an alternative synthetic pesticides. Additionally, have demonstrated promising hypoglycemic effects, suggesting in diabetes treatment. This synthesis represents significant advancement understanding highlighting wide activities. However, need further research is emphasized fully explore identification new mechanisms action, evaluation safety efficacy different contexts.

Language: Английский

Citations

2

Essential Oils for the Treatment and Management of Nonalcoholic Fatty Liver Disease (NAFLD) DOI Creative Commons
Tae-Hwa Kim, Mohammad Al Mijan,

Jeonga Lee

et al.

Natural Product Communications, Journal Year: 2024, Volume and Issue: 19(4)

Published: April 1, 2024

Nonalcoholic fatty liver disease (NAFLD), characterized by excessive fat accumulation, is a common linked to obesity, insulin resistance, and metabolic dysfunction. The lack of effective treatments against NAFLD has led an increasing focus on alternative natural remedies. Essential oils, extracted from variety plants, have drawn interest due their high content active compounds potential functions support health. Ginger essential oil, known for its anti-inflammatory, antioxidant, cholesterol-lowering properties, promotes antioxidant enzymes ameliorates accumulation in mice model NAFLD. Nigella sativa oil with diverse array bioactive components, mitigates lowering tumor necrosis factor-alpha, malonaldehyde (MDA), plasma lipids vivo human trials that could contribute management. Garlic rich organosulfur compounds, shown benefits modulating oxidative stress inflammation associated Similarly, oils turmeric, pepper, patchouli, basil reduced lipid enhanced metabolism animal models These findings underscore the use as complementary medicines NAFLD, opening avenues further research clinical applications.

Language: Английский

Citations

1

Exploring Folklore Ecuadorian Medicinal Plants and Their Bioactive Components Focusing on Antidiabetic Potential: An Overview DOI Creative Commons
Soham Bhattacharya, Neha Gupta,

Adéla Flekalová

et al.

Plants, Journal Year: 2024, Volume and Issue: 13(11), P. 1436 - 1436

Published: May 22, 2024

Diabetes mellitus (DM) is a global health concern characterized by deficiency in insulin production. Considering the systemic toxicity and limited efficacy associated with current antidiabetic medications, there utmost need for natural, plant-based alternatives. Herbal medicines have experienced exponential growth popularity globally recent years their natural origins minimal side effects. Ecuador has rich cultural history ethnobotany that plays crucial role its people’s lives. This study identifies 27 Ecuadorian medicinal plants are traditionally used diabetes treatment prepared through infusion, decoction, or juice, ingested raw forms. Among them, 22 demonstrated hypoglycemic anti-hyperglycemic properties bioactive phytochemicals, which was confirmed several vitro vivo studies. However, Bryophyllum gastonis-bonnieri, Costus villosissimus, Juglans neotropica, Pithecellobium excelsum, Myroxylon peruiferum, were extensively traditional medicine preparation many decades to treat diabetes, lacking pharmacological elucidation. The been found compounds such as flavonoids, phenolics, fatty acids, aldehydes, terpenoids mainly responsible reducing blood sugar levels oxidative stress, regulating intestinal function, improving resistance, inhibiting α-amylase α-glucosidase, lowering gluconeogenic enzymes, stimulating glucose uptake mechanisms, playing an important lipid metabolism. substantial lack of integrated approaches between existing ethnomedicinal practices research. Therefore, this review aims discuss explore treating DM properties. We believe use herbal scientifically sound way can substantially benefit local economy industries seeking products.

Language: Английский

Citations

1