Validation of a Questionnaire Assessing Pregnant Women’s Perspectives on Addressing the Psychological Challenges of Childbirth DOI Creative Commons
Mihaela Corina Radu, Mihai Sebastian Armean, Răzvan Daniel Chivu

et al.

Nursing Reports, Journal Year: 2024, Volume and Issue: 15(1), P. 8 - 8

Published: Dec. 31, 2024

Introduction: Pregnant women’s experiences and concerns regarding childbirth are complex, necessitating a multidimensional personalized approach in maternal care. This study explores the psychological emotional factors influencing pregnant decisions their mode of delivery. The results will provide valuable insights for development educational counseling strategies designed to support women making informed conscious about childbirth. Material method: cross-sectional aimed develop validate questionnaire exploring dimensions Factor analysis was employed assess perceptions, perceived medical risks, impact cesarean section on women. distributed online via Google Forms, using social networks like Facebook Instagram ensure rapid broad accessibility. available seven months, from January July 2023. Results: McDonald’s ω, Cronbach’s α, average inter-item correlation, total item correlations were calculated consistency items measuring same construct. three-factor model emerged as primary structure based exploratory confirmatory factor analyses (EFA CFA). first profile, centered benefits vaginal birth, highlights importance natural birth experience mother’s well-being. second profile addresses risks need interventions. third focuses perceptions related intelligence adaptability children born by effects anesthesia. Conclusions: Each reflects different seeking control security amid uncertainties. These include emphasizing addressing focusing interventions child development. Understanding these variables is essential providing appropriate psychosocial support, thereby optimizing promoting health both mother child. integration multi-factor single-factor models serves complementary purposes, distinct yet interrelated into instrument’s validity.

Language: Английский

Redox Homeostasis, Gut Microbiota, and Epigenetics in Neurodegenerative Diseases: A Systematic Review DOI Creative Commons
Constantin Munteanu, Anca‐Irina Galaction, Marius Turnea

et al.

Antioxidants, Journal Year: 2024, Volume and Issue: 13(9), P. 1062 - 1062

Published: Aug. 30, 2024

Neurodegenerative diseases encompass a spectrum of disorders marked by the progressive degeneration structure and function nervous system. These conditions, including Parkinson's disease (PD), Alzheimer's (AD), Huntington's (HD), Amyotrophic lateral sclerosis (ALS), Multiple (MS), often lead to severe cognitive motor deficits. A critical component neurodegenerative pathologies is imbalance between pro-oxidant antioxidant mechanisms, culminating in oxidative stress. The brain's high oxygen consumption lipid-rich environment make it particularly vulnerable damage. Pro-oxidants such as reactive nitrogen species (RNS) (ROS) are continuously generated during normal metabolism, counteracted enzymatic non-enzymatic defenses. In diseases, this balance disrupted, leading neuronal This systematic review explores roles stress, gut microbiota, epigenetic modifications aiming elucidate interplay these factors identify potential therapeutic strategies. We conducted comprehensive search articles published 2024 across major databases, focusing on studies examining relationships redox homeostasis, changes neurodegeneration. total 161 were included, comprising clinical trials, observational studies, experimental research. Our findings reveal that stress plays central role pathogenesis with microbiota composition significantly influencing balance. Specific bacterial taxa markers identified modulators suggesting novel avenues for intervention. Moreover, recent evidence from human animal supports emerging concept targeting homeostasis through therapies. Future research should focus validating targets settings exploring personalized medicine strategies based individual profiles.

Language: Английский

Citations

5
Actual data regarding the impact of viral respiratory co-infection (Covid 19 and flu/ Respiratory Syncutial Virus RSV) - A systematic review DOI Creative Commons

Alina-Maria Robu,

Gelu Onose,

Maria-Teodora Ulinici

et al.

Balneo and PRM Research Journal, Journal Year: 2024, Volume and Issue: 15(Vol.15, no.1), P. 671 - 671

Published: March 31, 2024

Abstract: Background. The impact of SARS-CoV-2 infection alongside with influenza and RSV, the major viral agents in pediatric disordes, may be an important concern to healthcare system. Clinical outcomes interaction are unknown. aim this systematic review is contribute at establishing prevalence co-infection, its clinical potential risk factors. Methods. A systematical literature search was performed for papers published PubMed, Scopus, Web Science, Pedro Cochrane Library, from January 2020 - beginning COVID 19 pandemic June 2023. Our conducted accordance Preferred Reporting Items Systematic Reviews Meta-Analyses (PRISMA) methods. Studies were eligible inclusion if they approached co-infection or available English. Due fact that studies on population scarce, we included patients all ages. Results. Out 159 articles found, 12 inclusion. between 5% % viruses 10% RSV. most common symptoms high-grade fever, cough, headache, shortness breath frequent complications pneumonia respir-atory distress. In terms laboratory findings, co-infected presented signifi-cant lymphopenia pronounced inflammatory response, as well a progressive ten-dency towards respiratory Regarding majority indicated simultaneous predisposes more severe course disease(s), longer length hospital stay increased death.Conclusion. study underlines frequency such co-infections, although not very high, hos-pitalisations stay, including admission intensive care outcomes, life-threatening events. It therefore essential determine epidemiological nowadays, order in-form adjust treatment control prevention strategies, limiting viruses. lack children, unable identify specific features co-infections population. Therefore, needed evaluate paediatric consequently, our doctoral research en-deavour warranted.

Language: Английский

Citations

2
A topical reappreasal on use of repetitive Transcranial Magnetic Stimulation in elderly patients with postischemic stroke statuses - a systematic literature review DOI Creative Commons

Valeria Madalina Alecu-Mihai,

A. Zamfirescu, Sorina Maria Aurelian

et al.

Balneo and PRM Research Journal, Journal Year: 2024, Volume and Issue: 15(Vol.15, no.1), P. 679 - 679

Published: March 31, 2024

Abstract: Introduction: Stroke is a cerebrovascular disease with an impressive potential of disabil-ity, (multi)morbidity, and mortality among elderly patients. After stroke, series seque-lae represents dynamic challenge for rehabilitation, especially improving motor, cognitive depressive disorders (1,2). Repetitive Transcranial Magnetic Stimulation (rTMS) non-invasive, painless, neuromodulations neurostimulation method, which uses electromagnetic induction to administer repeated trains pulses, thera-peutic, diagnostic research purposes (3–5). Method: We performed systematic literature review the related using widely international accepted method - Preferred Reporting Items Systematic Reviews Meta-Analyses (PRISMA)(6), by searching, filtering, selecting profile documen-tary material. Combinations/syntaxes keywords were searched in following interna-tional databases: Elsevier(7), PubMed(8), PMC(9), PEDro(10), ISI indexed journals Web Knowledge/Science(11) during 1/01/2019-31/12/2021. Besides 9 articles selected enhance our knowledge base we have also used some works freely identified literature. Results discussions: satisfied all previous filtering criteria/ PRISMA steps qualitative detailed analysis. The benefits rTMS, aiming bring further insight into responsiveness motor deficit, depression, impairment treatment, through favorable progress scores quantification scales used: HAMD-17/ HDRS, Hamilton Depression Scale; MMSE, Mini-Mental State Examination; MoCA, Montreal Cognitive Assesment; SCWT, Stroop Color-Word Interference Test; WAIS, Wechsler Adult Intelligence NIHSS, National Institutes Health Barthel Index Score; ADL, Activities Daily Living; mRS, modified Rankin FIM, Functional Independence Measures. Conclusions: Through this review, wish present perspective successful use rTMS intend work be start-ing point development doctoral study, will include post-stroke sequelae, such as deficits, disorders, strengthen scientific confidence tolerability effectiveness type stimula-tion segment age.

Language: Английский

Citations

2
An Actual Insight into the Pathogenic Pathways of Ankylosing Spondylitis DOI Creative Commons

Emilia-Daniela Păsăran,

Andreea Elena Diaconu,

Corina Oancea

et al.

Current Issues in Molecular Biology, Journal Year: 2024, Volume and Issue: 46(11), P. 12800 - 12812

Published: Nov. 11, 2024

Spondyloarthritis refers to a broad group of conditions that include ankylosing spondylitis, psoriatic arthritis, reactive and enteropathic arthritis associated with Crohn's disease or ulcerative colitis. They have been classified by the ASAS (ASsessment in Ankylosing Spondylitis) into axial spondyloarthritis peripheral spondyloarthritis. Common features absence autoantibodies, genetic predisposition, clinical aspects such as joint involvement, manifestations, extra-articular involvement. However, pathogenic mechanisms remain complex incompletely elucidated, despite fact specialized literature has described several pathways act synergy: environmental factors (infections mechanical stress), innate acquired immune mechanisms. Finally, an inflammatory response is triggered recruitment large number cells release cytokines affected areas: joints periarticular extraarticular tissues. The current article aims update systematize knowledge accumulated so far on this topic, focusing involved onset, progression, severity spondylitis.

Language: Английский

Citations

1
Defining and Categorizing Nonpharmacologic Interventions in the Older Population: A Systematic Review DOI Creative Commons
Eline C. M. Kooijmans, Emiel O. Hoogendijk,

Natalia Drapała

et al.

Journal of the American Medical Directors Association, Journal Year: 2024, Volume and Issue: unknown, P. 105306 - 105306

Published: Oct. 1, 2024

Language: Английский

Citations

0
Validation of a Questionnaire Assessing Pregnant Women’s Perspectives on Addressing the Psychological Challenges of Childbirth DOI Creative Commons
Mihaela Corina Radu, Mihai Sebastian Armean, Răzvan Daniel Chivu

et al.

Nursing Reports, Journal Year: 2024, Volume and Issue: 15(1), P. 8 - 8

Published: Dec. 31, 2024

Introduction: Pregnant women’s experiences and concerns regarding childbirth are complex, necessitating a multidimensional personalized approach in maternal care. This study explores the psychological emotional factors influencing pregnant decisions their mode of delivery. The results will provide valuable insights for development educational counseling strategies designed to support women making informed conscious about childbirth. Material method: cross-sectional aimed develop validate questionnaire exploring dimensions Factor analysis was employed assess perceptions, perceived medical risks, impact cesarean section on women. distributed online via Google Forms, using social networks like Facebook Instagram ensure rapid broad accessibility. available seven months, from January July 2023. Results: McDonald’s ω, Cronbach’s α, average inter-item correlation, total item correlations were calculated consistency items measuring same construct. three-factor model emerged as primary structure based exploratory confirmatory factor analyses (EFA CFA). first profile, centered benefits vaginal birth, highlights importance natural birth experience mother’s well-being. second profile addresses risks need interventions. third focuses perceptions related intelligence adaptability children born by effects anesthesia. Conclusions: Each reflects different seeking control security amid uncertainties. These include emphasizing addressing focusing interventions child development. Understanding these variables is essential providing appropriate psychosocial support, thereby optimizing promoting health both mother child. integration multi-factor single-factor models serves complementary purposes, distinct yet interrelated into instrument’s validity.

Language: Английский

Citations

0