Practical Recommendations for Exercise Training in Patients with Long COVID with or without Post-exertional Malaise: A Best Practice Proposal

Sports Medicine - Open, Journal Year: 2024, Volume and Issue: 10(1)

Published: April 24, 2024

Abstract People with long COVID may suffer from a wide range of ongoing symptoms including fatigue, exertional dyspnea, reduced exercise performance, and others. In particular, impaired performance is condition that can be recovered in many people through an individualized physical training program. However, clinical experience has shown the presence post-exertional malaise (PEM) significant barrier to COVID. Currently, there no guideline or consensus available on how apply this cohort. Therefore, we conducted literature review PubMed library using following search terms: “COVID”, “post-COVID”, “long COVID” “exercise” searching for studies January 2020 2024. Data 46 trials were included. Exercise regimes very heterogeneous none these reported management PEM context Based feedback additional survey was answered by 14 international experts field COVID, combined authors´ own extensive practical experience, best practice proposal recommendations been developed. This differentiates procedures according no, mild/moderate severe These guide allied healthcare professionals worldwide initiating adjusting programs stratified severity PEM.

Language: Английский

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Functional and Psychological Changes after Exercise Training in Post-COVID-19 Patients Discharged from the Hospital: A PRISMA-Compliant Systematic Review

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(4), P. 2290 - 2290

Published: Feb. 17, 2022

Millions of people worldwide are infected with COVID-19, and COVID-19 survivors have been found to suffer from functional disabilities mental disorders such as depression anxiety. This is a matter concern because still not over. Because reinfection possible in survivors, decreased physical function increased stress anxiety can lower immune function. However, the optimal exercise intensity volume appear remain unknown. Therefore, current systematic review aimed evaluate effect resistance or aerobic exercises post-COVID-19 patients after hospital discharge. We conducted searches Scopus, SciELO, PubMed, Web Science, Science Direct, Google Scholar databases. Studies that met following criteria were included: (i) English language, (ii) involved programs Out 381 studies reviewed, seven inclusion criteria. Evidence shows composed (e.g., 1–2 sets 8–10 repetitions at 30–80% 1RM) along 5 30 min moderate intensity) may improve capacity quality life (reduce disorders) patients. In addition, only one study reported three subjects program, suggesting be feasible for rehabilitation A meta-analysis was included methodological heterogeneities, they did examine control group. Consequently, results should generalized caution.

Language: Английский

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Prevalence, risk factors and treatments for post-COVID-19 breathlessness: a systematic review and meta-analysis

European Respiratory Review, Journal Year: 2022, Volume and Issue: 31(166), P. 220071 - 220071

Published: Nov. 2, 2022

Persistent breathlessness >28 days after acute COVID-19 infection has been identified as a highly debilitating post-COVID symptom. However, the prevalence, risk factors, mechanisms and treatments for remain poorly understood. We systematically searched PubMed Embase relevant studies published from 1 January 2020 to November 2021 (PROSPERO registration number: CRD42021285733) included 119 eligible papers. Random-effects meta-analysis of 42 872 patients with reported in 102 papers found an overall prevalence 26% (95% CI 23-29) when measuring presence/absence symptom, 41% 34-48) using Medical Research Council (MRC)/modified MRC dyspnoea scale. The pooled decreased significantly 1-6 months 7-12 post-infection. Post-COVID was more common those severe/critical infection, who were hospitalised females, less likely be by Asia than Europe or North America. Multiple pathophysiological have proposed (including deconditioning, restrictive/obstructive airflow limitation, systemic inflammation, impaired mental health), but body evidence remains inconclusive. Seven cohort one randomised controlled trial suggested rehabilitation exercises may reduce breathlessness. There is urgent need mechanistic research development interventions prevention treatment

Language: Английский

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Fatigue outcomes following COVID-19: a systematic review and meta-analysis

BMJ Open, Journal Year: 2023, Volume and Issue: 13(4), P. e063969 - e063969

Published: April 1, 2023

Objectives Fatigue is a pervasive clinical symptom in coronaviruses and may continue beyond the acute phase, lasting for several months or years. This systematic review meta-analysis aimed to incorporate current evidence postinfection fatigue among survivors of SARS-CoV-2 investigate associated factors. Methods Embase, PsyINFO, Medline, CINAHL, CDSR, Open Grey, BioRxiv MedRxiv were systematically searched from January 2019 December 2021. Eligible records included all study designs English. Outcomes vitality adults with confirmed diagnosis measured at >30 days post infection. Non-confirmed cases excluded. JBI risk bias was assessed by three reviewers. Random effects model used pooled proportion 95% CIs. A mixed meta-regression 35 prospective articles calculated change overtime. Subgroup analyses explored specific group characteristics methodology. Heterogeneity using Cochran’s Q I 2 statistic. Egger’s tests publication bias. Results Database searches returned 14 262 records. Following deduplication screening, 178 identified. 147 (n=48 466 participants) meta-analyses. Pooled prevalence 41% (95% CI: 37% 45%, k=147, =98%). significantly reduced over time (−0.057, −107 −0.008, k=35, =99.3%, p=0.05). higher found studies valid scale (51%, 43% 58%, k=36, =96.2%, p=0.004). No significant difference design (p=0.272). test indicated except scales. Quality assessments 4% low bias, 78% moderate 18% high risk. Frequently reported associations female gender, age, physical functioning, breathlessness psychological distress. Conclusion revealed that experienced following their Non-modifiable factors morbidity contribute ongoing impede recovery. PROSPERO registration number CRD42020201247.

Language: Английский

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Digital Interventions for Treating Post-COVID or Long-COVID Symptoms: Scoping Review

Journal of Medical Internet Research, Journal Year: 2023, Volume and Issue: 25, P. e45711 - e45711

Published: March 10, 2023

Background Patients with post-COVID/long-COVID symptoms need support, and health care professionals to be able provide evidence-based patient care. Digital interventions can meet these requirements, especially if personal contact is limited. Objective We reviewed digital that are currently available help manage physical mental in patients symptoms. Methods A scoping review was carried out summarizing novel for treating patients. Using the PICO (population, intervention, comparison, outcome) scheme, original studies were summarized, which used aid recovery. Results From all scanned articles, 8 matched inclusion criteria. Of studies, 3 “pretest” described implementation of a telerehabilitation program, 1 results qualitative interviews who an online peer-support group. Following we summarized previous studies. Studies varied terms participants (P), ranging from adults different countries, such as former hospitalized COVID-19, individuals disadvantaged communities United Kingdom, well workers. In addition, included had previously been infected COVID-19 ongoing Some focused on specific symptoms, including those either post–COVID-19 or long-term while other based participation groups. The (I) also varied. Most combination psychological exercises, but they duration, frequency, social dimensions. investigated conditions no control (C) group, most reported outcomes (O) improvements physiological perception, some conditions, fatigue, aspects depression. However, found bowel bladder problems, concentration, short-term memory, unpleasant dreams, ailments, perceived bodily pain, emotional health. Conclusions More systematic research larger sample sizes required overcome sampling bias include professionals’ perspectives, mobilize support network partners. evidence so far suggests should provided reintegrate into everyday life, work.

Language: Английский

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Effectiveness of a telerehabilitation intervention using ReCOVery APP of long COVID patients: a randomized, 3-month follow-up clinical trial

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: May 16, 2023

The main objective of this study is to analyze the clinical efficacy telerehabilitation in recovery Long COVID patients through ReCOVery APP for 3 months, administered Primary Health Care context. second identify significant models associated with an improvement variables. An open-label randomized trial was conducted using two parallel groups a total 100 patients. first group follows treatment as usual methods established by their general practitioner (control group) and same also uses (intervention group). After intervention, no differences were found favour intervention. Regarding adherence, 25% participants made use APP. Linear regression model establishes that time predicts physical function (b = 0.001; p 0.005) community social support 0.004; 0.021). In addition, increase self-efficacy health literacy contribute improving cognitive 0.346; 0.001) reducing number symptoms 0.226; 0.002), respectively. conclusion, can Trial Registration No.: ISRCTN91104012.

Language: Английский

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Non-Pharmacological Therapies for Post-Viral Syndromes, Including Long COVID: A Systematic Review

International Journal of Environmental Research and Public Health, Journal Year: 2023, Volume and Issue: 20(4), P. 3477 - 3477

Published: Feb. 16, 2023

Background: Post-viral syndromes (PVS), including Long COVID, are symptoms sustained from weeks to years following an acute viral infection. Non-pharmacological treatments for these poorly understood. This review summarises the evidence effectiveness of non-pharmacological PVS. Methods: We conducted a systematic evaluate interventions PVS, as compared either standard care, alternative therapy, or placebo. The outcomes interest were changes in symptoms, exercise capacity, quality life (including mental health and wellbeing), work capability. searched five databases (Embase, MEDLINE, PsycINFO, CINAHL, MedRxiv) randomised controlled trials (RCTs) published between 1 January 2001 29 October 2021. relevant outcome data extracted, study was appraised using Cochrane risk-of-bias tool, findings synthesised narratively. Findings: Overall, studies different (Pilates, music telerehabilitation, resistance exercise, neuromodulation) met inclusion criteria. Aside music-based intervention, all other selected demonstrated some support management PVS patients. Interpretation: In this study, we observed lack robust evaluating COVID. Considering prevalence prolonged infections, there is urgent need clinical cost-effectiveness patients with Registration: protocol registered PROSPERO [CRD42021282074] 2021 BMJ Open 2022.

Language: Английский

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Effect of Physical Exercise–Based Rehabilitation on Long COVID: A Systematic Review and Meta-analysis

Medicine & Science in Sports & Exercise, Journal Year: 2023, Volume and Issue: unknown

Published: Aug. 16, 2023

The number of persons living with post-coronavirus disease 2019 (COVID-19) conditions or long COVID continues to rise worldwide; however, the etiology and treatment remain nebulous. Therefore, efficient, feasible, cost-effective therapeutic strategies for a large population warranted. Physical exercise-based rehabilitation is promising strategy COVID, although its effects be determined. This systematic review meta-analysis aimed examine physical on COVID.The electronic databases Medline, Embase, Global Health (Ovid), CINAHL (EBSCO), Web Science, WHO Research Database COVID-19, LitCovid, Google Scholar were searched from their inception November 2022. identified articles independently screened by three reviewers, random-effects model was used determine mean differences in meta-analysis.Twenty-three studies involving 1579 individuals who had COVID-19 (752 women) included. showed beneficial COVID-related symptoms characterized dyspnea, fatigue, depression, as well 6-min walk test, forced expiratory volume 1 s/forced vital capacity, quality life people COVID-19.Physical potential against can applied routine clinical practice have recovered COVID-19. However, customized programs specific types require future large-scale studies.

Language: Английский

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Pulmonary Rehabilitation for People With Persistent Symptoms After COVID-19

CHEST Journal, Journal Year: 2024, Volume and Issue: 166(3), P. 461 - 471

Published: Jan. 19, 2024

Language: Английский

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Clinical effectiveness of rehabilitation in ambulatory care for patients with persisting symptoms after COVID-19: a systematic review

BMC Infectious Diseases, Journal Year: 2023, Volume and Issue: 23(1)

Published: June 21, 2023

Lingering symptoms after acute COVID-19 present a major challenge to ambulatory care services. Since there are reservations regarding their optimal management, we aimed collate all available evidence on the effects of rehabilitation treatments applicable in for these patients.

Language: Английский

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