Fermentation's pivotal role in shaping the future of plant-based foods: An integrative review of fermentation processes and their impact on sensory and health benefits

Applied Food Research, Journal Year: 2024, Volume and Issue: 4(2), P. 100468 - 100468

Published: Aug. 9, 2024

Given the environmental, ethical, and food security challenges posed by conventional agriculture animal husbandry, transition towards sustainable systems is essential. Plant-based foods, especially those enhanced fermentation, present a viable solution. Fermentation reduces ecological footprint, aligns with ethical standards, enhances plant-based proteins' nutritional value sensory attributes, offering credible alternative to products. This paper explores fermentation's transformative role in developing meats, dairy, protein alternatives, emphasizing its benefits, including improved gut health through probiotics prebiotics. It also addresses such as producing undesirable by-products, potential risks, increased costs associated fermentation. Detailed examinations of specific fermentation processes—alcoholic, lactic acid, acetic propionic butyric acid—and their impact on enhancing value, digestibility, flavor foods are presented. Case studies from pioneering companies demonstrate technologies' practical applications market potential. Lastly, discusses future opportunities scaling up processes incorporating advanced biotechnological techniques further enhance sustainability outcomes.

Language: Английский

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Probiotics and Food Bioactives: Unraveling Their Impact on Gut Microbiome, Inflammation, and Metabolic Health

Probiotics and Antimicrobial Proteins, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 14, 2025

Language: Английский

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The Beneficial Effects of Lactobacillus Strains on Gut Microbiome in Alzheimer’s Disease: A Systematic Review

Healthcare, Journal Year: 2025, Volume and Issue: 13(1), P. 74 - 74

Published: Jan. 3, 2025

Background/Objectives: Growing evidence suggests that the gut–brain axis influences brain function, particularly role of intestinal microbiota in modulating cognitive processes. Probiotics may alter function and behavior by gut microbiota, with implications for neurodegenerative diseases like Alzheimer’s disease (AD). The purpose this review is to systematically current literature exploring effects probiotic supplementation on AD mild impairment (MCI). Methods: A comprehensive search was conducted across PubMed/Medline, Embase, Scopus identify relevant randomized controlled trials (RCTs) from inception 20 August 2024. focused comparing outcomes between intervention control/placebo groups. Data searches, article selection, data extraction, risk bias assessment were performed accordance Cochrane guidelines. Systematic Review Registration: PROSPERO registration no: CRD42023446796. Results: four RCTs involving 293 Individuals (AD MCI patients) receiving mainly Lactobacillus Bifidobacterium strains showed some beneficial altered composition, positively affected metabolic biomarkers. However, variability studies limits interpretation results. limited number quality existing make it difficult draw definitive conclusions data. Additional high-quality research clearly needed. Conclusions: show promise as an adjunctive decline, but larger, long-term are needed confirm their efficacy clinical applicability AD.

Language: Английский

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Chronic Endometritis and Antimicrobial Resistance: Towards a Multidrug-Resistant Endometritis? An Expert Opinion

Microorganisms, Journal Year: 2025, Volume and Issue: 13(1), P. 197 - 197

Published: Jan. 17, 2025

Chronic endometritis (CE) is a persistent inflammatory condition of the endometrium characterized by abnormal infiltration plasma cells into endometrial stroma. Frequently associated with repeated implantation failure, recurrent pregnancy loss, and infertility, CE significantly impacts women's health, contributing to conditions such as uterine bleeding endometriosis. Treatment typically involves antibiotic therapy; however, efficacy these treatments increasingly compromised rise antimicrobial resistance (AMR). This paper examines critical links between AMR CE, proposing strategies enhance clinical management optimize treatment outcomes.

Language: Английский

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Probiotics and nanoparticle-mediated nutrient delivery in the management of transfusion-supported diseases

Frontiers in Cellular and Infection Microbiology, Journal Year: 2025, Volume and Issue: 15

Published: April 11, 2025

Bone marrow is vital for hematopoiesis, producing blood cells essential oxygen transport, immune defense, and clotting. However, disorders like leukemia, lymphoma, aplastic anemia, myelodysplastic syndromes can severely disrupt its function, leading to life-threatening complications. Traditional treatments, including chemotherapy stem cell transplants, have significantly improved patient outcomes but are often associated with severe side effects limitations, necessitating the exploration of safer, more targeted therapeutic strategies. Nanotechnology has emerged as a promising approach addressing these challenges, particularly in delivery nutraceuticals—bioactive compounds derived from food sources potential benefits. Despite their promise, nutraceuticals face clinical limitations due poor bioavailability, instability, inefficient target sites. Nanoparticles offer viable solution by enhancing stability, absorption, transport bone while minimizing systemic effects. This study explores range disorders, conventional treatment modalities, nanoparticles enhance nutraceutical-based therapies. By improving efficacy, could revolutionize disease management, providing patients effective less invasive options. These advancements represent significant step toward safer efficient approaches, ultimately prognosis overall health.

Language: Английский

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Role of Microbiota-Derived Hydrogen Sulfide (H2S) in Modulating the Gut–Brain Axis: Implications for Alzheimer’s and Parkinson’s Disease Pathogenesis

Biomedicines, Journal Year: 2024, Volume and Issue: 12(12), P. 2670 - 2670

Published: Nov. 23, 2024

Microbiota-derived hydrogen sulfide (H2S) plays a crucial role in modulating the gut–brain axis, with significant implications for neurodegenerative diseases such as Alzheimer’s and Parkinson’s. H2S is produced by sulfate-reducing bacteria gut acts critical signaling molecule influencing brain health via various pathways, including regulating inflammation, oxidative stress, immune responses. maintains barrier integrity at physiological levels prevents systemic which could impact neuroinflammation. However, has dual or Janus face, excessive production, often resulting from dysbiosis, can compromise intestinal exacerbate processes promoting neuroinflammation glial cell dysfunction. This imbalance linked to early pathogenesis of Parkinson’s diseases, where overproduction exacerbates beta-amyloid deposition, tau hyperphosphorylation, alpha-synuclein aggregation, driving neuroinflammatory responses neuronal damage. Targeting microbiota restore homeostasis through dietary interventions, probiotics, prebiotics, fecal transplantation presents promising therapeutic approach. By rebalancing microbiota-derived H2S, these strategies may mitigate neurodegeneration offer novel treatments underscoring axis maintaining central nervous system health.

Language: Английский

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Evaluating the health risk of probiotic supplements from the perspective of antimicrobial resistance

Microbiology Spectrum, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 10, 2024

ABSTRACT Antimicrobial resistance remains a public health threat. Probiotics harboring antimicrobial resistant genes (ARGs) have, in recent years, been considered potential risk. Studies conducted on probiotics from increasingly popular supplements have raised the possibility of transmitting ARGs to commensals human gut, concomitantly establishing reservoir and risking acquisition by opportunistic pathogens. Building our previous study that reported multiple antibiotic supplements, this research, we attempted detect their may account for phenotypes. responsible tetracycline, macrolide, aminoglycoside, glycopeptide were prevalent probiotics. Through laboratory adaptive evolution studies, also show streptomycin-adapted gained erythromycin, doxycycline more effectively than non-adapted ones. When co-incubated with Enterococcus faecalis , Escherichia coli or Staphylococcus aureus Caco-2 and/or HCT-116 cells, streptomycin was transferred adapted generate transconjugants at frequencies comparable higher other studies through filter mating. Consistently, conferring ( aadA ) erythromycin [ erm(B)−1 ] detected E. S. transconjugants, respectively, after co-incubation cells. both transconjugant same Our data future comparative genomics metagenomics animal models healthy, immunocompromised, antibiotic-treated cohorts will contribute comprehensive understanding probiotic consumption, application, safety. IMPORTANCE are becoming popular, promising applications food medicine, but risk transferring disease-causing bacteria has concerns. drugs. Streptomycin-adapted antibiotics Importantly, showed could be intestinal resistance, which initially absent recipient bacteria, transconjugants. build foundation humans leveraging advanced approaches clarify long-term consumption.

Language: Английский

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The Gut Microbiome-Neuroglia Axis: Implications for Brain Health, Inflammation, and Disease

Neuroglia, Journal Year: 2024, Volume and Issue: 5(3), P. 254 - 273

Published: Aug. 1, 2024

The human central nervous system is convolutedly connected to the gut microbiome, a diverse community of microorganisms residing in gastrointestinal tract. Recent research has highlighted bidirectional communication between microbiome and neuroglial cells, which include astrocytes, microglia, oligodendrocytes, ependymal cells. These cells are essential for maintaining CNS homeostasis, supporting neuronal function, responding pathological conditions. This review examines interactions neuroglia, emphasizing their critical roles brain health development neurological disorders. Dysbiosis, or imbalance been associated with various psychiatric conditions, such as autism spectrum disorder, anxiety, depression, neurodegenerative diseases like Alzheimer’s Parkinson’s. influences function through microbial metabolites, immune modulation, neuroinflammatory responses. Understanding these paves way new therapeutic targets strategies preventing treating scoping aims highlight mechanisms microbiome-neuroglia axis its potential target.

Language: Английский

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Isolation and Immunomodulatory Activity of Cyanidin-3-O-(3,6-O-dimalonyl-β-D-glucoside) from the Black Corncob (Zea mays L.) and its Effect on Gut Microbiota in Elderly Feces under Anaerobic Conditions in vitro

Plant Foods for Human Nutrition, Journal Year: 2025, Volume and Issue: 80(1)

Published: Feb. 10, 2025

Language: Английский

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Systematic Reviews to Inform Practice, March/April 2025

Journal of Midwifery & Women s Health, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

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