Nutrition and Breast Cancer: A Literature Review on Prevention, Treatment and Recurrence

Nutrients, Journal Year: 2019, Volume and Issue: 11(7), P. 1514 - 1514

Published: July 3, 2019

Breast cancer (BC) is the second most common worldwide and commonly occurring malignancy in women. There growing evidence that lifestyle factors, including diet, body weight physical activity, may be associated with higher BC risk. However, effect of dietary factors on recurrence mortality not clearly understood. Here, we provide an overview current obtained from PubMed databases last decade, assessing patterns, as well consumption specific food-stuffs/food-nutrients, relation to incidence, survival. Data published literature suggest a healthy pattern characterized by high intake unrefined cereals, vegetables, fruit, nuts olive oil, moderate/low saturated fatty acids red meat, might improve overall survival after diagnosis BC. patients undergoing chemotherapy and/or radiotherapy experience variety symptoms worsen patient quality life. Studies investigating nutritional interventions during treatment have shown counselling supplementation some constituents, such EPA DHA, useful limiting drug-induced side effects, enhancing therapeutic efficacy. Therefore, intervention considered integral part multimodal approach. further research utilizing large clinical trials required definitively establish effective these patients, long-term

Language: Английский

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Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects

Cell Metabolism, Journal Year: 2021, Volume and Issue: 33(8), P. 1701 - 1715.e5

Published: June 11, 2021

Language: Английский

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Lipid Droplets in Cancer: Guardians of Fat in a Stressful World

Molecules, Journal Year: 2018, Volume and Issue: 23(8), P. 1941 - 1941

Published: Aug. 3, 2018

Cancer cells possess remarkable abilities to adapt adverse environmental conditions. Their survival during severe nutrient and oxidative stress depends on their capacity acquire extracellular lipids the plasticity of mechanisms for intracellular lipid synthesis, mobilisation, recycling. Lipid droplets, cytosolic fat storage organelles present in most from yeast men, are emerging as major regulators metabolism, trafficking, signalling various tissues exposed stress. biogenesis is induced by they accumulate cancers. droplets act switches that coordinate trafficking consumption different purposes cell, such energy production, protection against or membrane rapid cell growth. They sequester toxic lipids, fatty acids, cholesterol ceramides, thereby preventing lipotoxic damage engage a complex relationship with autophagy. Here, we focus stress-induced droplet biogenesis; roles nutrient, lipotoxic, stress; between The recently discovered principles biology can improve our understanding govern cancer adaptability resilience

Language: Английский

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An Overview of Potential Oleaginous Microorganisms and Their Role in Biodiesel and Omega-3 Fatty Acid-Based Industries

Microorganisms, Journal Year: 2020, Volume and Issue: 8(3), P. 434 - 434

Published: March 19, 2020

Microorganisms are known to be natural oil producers in their cellular compartments. that accumulate more than 20%

Language: Английский

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Potential Role of Natural Antioxidant Products in Oncological Diseases

Antioxidants, Journal Year: 2023, Volume and Issue: 12(3), P. 704 - 704

Published: March 12, 2023

Nutrition has a significant effect and crucial role in disease prevention. Low consumption of fruit vegetables sedentary lifestyle are closely related with the onset development many types cancer. Recently, nutraceuticals have gained much attention cancer research due to their pleiotropic effects relatively non-toxic behavior. In fact, although past there been conflicting results on some antioxidant compounds as allies against cancer, numerous recent clinical studies highlight efficacy dietary phytochemicals prevention treatment However, further investigation is necessary gain deeper understanding potential anticancer capacities well mechanisms action. Therefore, this review examined current literature key properties bioactive components present diet, such carotenoids, polyphenols, compounds, use therapy. The focused chemopreventive properties, evaluating synergistic drugs and, consequently, side associated treatments.

Language: Английский

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Omega-3 long-chain polyunsaturated fatty acids: Metabolism and health implications

Progress in Lipid Research, Journal Year: 2023, Volume and Issue: 92, P. 101255 - 101255

Published: Oct. 13, 2023

Language: Английский

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Omega-3 fatty acids from fish by-products: Innovative extraction and application in food and feed

Food and Bioproducts Processing, Journal Year: 2024, Volume and Issue: 145, P. 32 - 41

Published: Feb. 26, 2024

Omega-3 fatty acids (O3FA) are essential nutrients that play a crucial role in maintaining human and animal health. They known for their numerous health claims, including cardiovascular benefits, contributing to both the prevention treatment of immunological, neurological, reproductive, complications, supporting overall well-being. Fish, especially oily fish, comprise rich source O3FA. In fish industry, significant amounts by-products waste generated during processing which often discarded or used lower-value applications. However, there is recognition potential value extracting O3FA from these by-products. Various extraction techniques can be used, but goal efficiently extract concentrate while minimizing loss nutritional value. To prevent oxidation maintain stability O3FA, natural antioxidants added. Antioxidants like polyphenolic compounds plant extracts help protect degradation caused by exposure oxygen, light, heat. By stabilizing shelf life extracted product extended. summary, this work presents forward-looking strategy transforming into high-quality oils, hold great application food feed.

Language: Английский

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Low-density lipoprotein docosahexaenoic acid nanoparticles induce ferroptotic cell death in hepatocellular carcinoma

Free Radical Biology and Medicine, Journal Year: 2017, Volume and Issue: 112, P. 597 - 607

Published: Sept. 8, 2017

Language: Английский

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Comparison of the nutritional value of mysore thorn borer (Anoplophora chinensis) and mealworm larva (Tenebrio molitor): Amino acid, fatty acid, and element profiles

Food Chemistry, Journal Year: 2020, Volume and Issue: 323, P. 126818 - 126818

Published: April 15, 2020

Language: Английский

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Dietary Fat and Cancer—Which Is Good, Which Is Bad, and the Body of Evidence

International Journal of Molecular Sciences, Journal Year: 2020, Volume and Issue: 21(11), P. 4114 - 4114

Published: June 9, 2020

A high-fat diet (HFD) induces changes in gut microbiota leading to activation of pro-inflammatory pathways, and obesity, as a consequence overnutrition, exacerbates inflammation, known risk factor not only for cancer. However, experimental data showed that the composition dietary fat has greater impact on pathogenesis cancer than total content isocaloric diets. Similarly, human studies did prove decrease intake is an effective strategy combat Saturated long been considered harmful, but current consensus moderate saturated fatty acids (SFAs), including palmitic acid (PA), does pose health within balanced diet. In regard monounsaturated fat, plant sources are recommended. The consumption (MUFAs), particularly from olive oil, associated with lower risk. replacement animal MUFAs decreased mortality. polyunsaturated (PUFAs) depends ratio between ω-6 ω-3 PUFAs. vivo stimulatory effects PUFAs tumour growth while were protective, results promising indicated preclinical reports. As trans FAs (TFAs), mostly opposite industrially produced natural TFAs, latter being protective against progression, mixed, no clear conclusion can be made. Further warranted establish role control cell order find prevention/treatment.

Language: Английский

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