Nutrients,
Journal Year:
2023,
Volume and Issue:
15(6), P. 1310 - 1310
Published: March 7, 2023
In
order
to
understand
how
omega-3
polyunsaturated
fatty
acid
(ω-3
PUFA)
supplements
affect
breast
cancer
prevention
and
treatment,
a
systematic
review
of
articles
published
in
the
last
5
years
two
databases
was
performed.
Of
679
identified,
only
27
were
included
examined
based
on
five
topics,
taking
into
account:
induction
type
used
animal
models;
characteristics
model
by
cell
transplantation;
experimental
design
ω-3
supplementation—combined
or
not
with
treatment
antitumor
drug;
acids
(FAs)
composition
used;
analysis
studies’
outcomes.
There
are
diverse
well-established
models
literature,
very
relevant
histological
molecular
similarities
depending
specific
objective
study,
such
as
whether
method
tumor
transgenic,
transplantation,
oncogenic
drugs.
The
analyses
outcomes
mainly
focused
monitoring
growth,
body/tumor
weight,
molecular,
genetic,
analyses,
few
studies
evaluated
latency,
survival,
metastases.
best
results
occurred
when
supplementation
PUFA
associated
drugs,
especially
metastases
volume/weight
tumors
started
early
maintained
for
long
time.
However,
beneficial
effect
an
agent
remains
unclear.
Cancers,
Journal Year:
2022,
Volume and Issue:
14(10), P. 2569 - 2569
Published: May 23, 2022
Breast
cancer
is
the
most-commonly
diagnosed
malignant
tumor
in
women
world,
as
well
first
cause
of
death
from
tumors.
The
incidence
breast
constantly
increasing
all
regions
world.
For
this
reason,
despite
progress
its
detection
and
treatment,
which
translates
into
improved
mortality
rates,
it
seems
necessary
to
look
for
new
therapeutic
methods,
predictive
prognostic
factors.
Treatment
strategies
vary
depending
on
molecular
subtype.
treatment
multidisciplinary;
includes
approaches
locoregional
therapy
(surgery
radiation
therapy)
systemic
therapy.
Systemic
therapies
include
hormone
hormone-positive
disease,
chemotherapy,
anti-HER2
HER2-positive
quite
recently,
immunotherapy.
Triple
negative
responsible
more
than
15–20%
cancers.
It
particular
research
interest
presents
a
challenge,
mainly
due
low
response
highly
invasive
nature.
Future
concepts
aim
individualize
de-escalate
escalate
based
biology
early
article
review
literature
carcinoma—a
disease
affecting
Cell Death and Disease,
Journal Year:
2020,
Volume and Issue:
11(10)
Published: Oct. 24, 2020
Abstract
N6-methyladenosine
(m
6
A)
serves
as
the
most
common
and
conserved
internal
transcriptional
modification.
However,
roles
of
m
A
on
cervical
cancer
(CC)
tumorigenesis
are
still
unclear.
Here,
results
indicated
that
METTL3
was
significantly
upregulated
in
CC
tissue
cells,
which
closely
correlated
with
lymph
node
metastasis
poor
prognosis
patients.
MeRIP-Seq
analysis
revealed
profiles
cells.
Functionally,
promoted
proliferation
Warburg
effect
(aerobic
glycolysis)
Mechanistically,
targeted
3’-Untranslated
Region
(3’-UTR)
hexokinase
2
(HK2)
mRNA.
Moreover,
recruited
YTHDF1,
a
reader,
to
enhance
HK2
stability.
These
findings
demonstrated
enhanced
stability
through
YTHDF1-mediated
modification,
thereby
promoting
CC,
might
promote
novel
insight
for
treatment.
Journal of Functional Foods,
Journal Year:
2020,
Volume and Issue:
74, P. 104172 - 104172
Published: Sept. 8, 2020
This
article
reviewed
inhibitory
activities
of
green
tea
catechins
(GTCs)
against
various
tumorigenesis
and
their
suppressive
effects
on
cancer
cell
progression,
metastasis,
angiogenesis
according
to
a
great
number
kinds
literature,
then
summarized
the
mechanisms
catechins-mediated
prevention
in
types.
Special
emphasis
was
placed
summarizing
recent
research
highlighting
related
techniques
improving
GTCs'
effectiveness
tumor
progression
and/or
treatment
cancers.
Synergistic
when
combined
with
other
phytochemicals
drugs,
nanostructure-
based
delivery
system,
molecular
modifications
EGCG
as
means
were
discussed,
thus
provide
basis
better
utilize
GTCs
main
ingredient
functional
foods
reduce
risk
human
cancer.
World Journal of Virology,
Journal Year:
2021,
Volume and Issue:
10(5), P. 229 - 255
Published: Sept. 16, 2021
In
view
of
the
advancement
in
understanding
about
most
diverse
types
cancer
and
consequently
a
relentless
search
for
cure
increased
survival
rates
patients,
finding
therapy
that
is
able
to
combat
mechanism
aggression
this
disease
extremely
important.
Thus,
oncolytic
viruses
(OVs)
have
demonstrated
great
benefits
treatment
because
it
mediates
antitumor
effects
several
ways.
Viruses
can
be
used
infect
cells,
especially
over
normal
present
tumor-associated
antigens,
activate
"danger
signals"
generate
less
immune-tolerant
tumor
microenvironment,
serve
transduction
vehicles
expression
inflammatory
immunomodulatory
cytokines.
The
success
therapies
using
OVs
was
initially
by
use
genetically
modified
herpes
virus,
talimogene
laherparepvec,
melanoma.
At
time,
are
being
studied
as
potential
clinical
trials.
However,
necessary
aware
safety
possible
adverse
therapy;
after
all,
an
effective
should
promote
regression,
attack
tumor,
meantime
induce
minimal
systemic
repercussions.
manuscript,
we
will
current
review
action
OVs,
main
uses,
updates,
future
perspectives
on
treatment.
Frontiers in Public Health,
Journal Year:
2022,
Volume and Issue:
10
Published: March 23, 2022
Global
cancer
statistics
suggest
that
breast
(BC)
is
the
most
diagnosed
in
women,
with
an
estimated
2.
3
million
new
cases
reported
2020.
Observational
evidence
shows
a
clear
link
between
prevention
and
development
of
invasive
BC
lifestyle-based
interventions
such
as
healthy
diet
physical
activity.
The
recent
findings
reveal
even
minimal
amounts
daily
exercise
reduced
risk
BC,
mitigated
side
effects
treatment,
stopped
recurrence
survivors.
Despite
myriad
benefits,
implementation
these
lifestyle
at-risk
survivor
populations
has
been
limited
to
date.
Given
need
disseminate
information
about
role
activity
nutrition
reduction,
review
aimed
present
scientific
outreach
update
on
associations
outcomes
narrow
gap
strengthen
understanding
more
clearly.
This
covers
direct,
detailed,
updated
literature
respond
frequently
asked
questions
related
their
impact
also
highlights
importance
oncology
provider's
job
how
education
can
reduce
burden.
Frontiers in Oncology,
Journal Year:
2023,
Volume and Issue:
12
Published: Jan. 12, 2023
Breast
cancer
is
a
pathology
suffered
by
millions
of
women
worldwide,
affecting
the
mental
health,
quality
life
(QoL),
physical
functioning,
cognitive
and
social
work
surviving
patients.
Moreover,
breast
associated
with
weight
gain,
muscle
atrophy,
weakness.
Physical
exercise
appears
to
be
an
effective
non-pharmacological
treatment
improve
short-term
self-esteem,
QoL,
fatigue,
psychological
factors
such
as
depression,
anxiety,
happiness,
body
image.
The
practice
activity
also
reduction
in
side
effects
treatment.
This
bibliometric
analysis
analyzed
trend
followed
publications
on
activity.
Web
Science
database
was
used,
laws
were
applied
identify
most
prolific
authors,
journals
involved
field,
countries,
institutions,
keywords
used
authors.
have
exponential
number
publications,
Psycho-Oncology
being
journal
highest
publications.
International Journal of Surgery,
Journal Year:
2024,
Volume and Issue:
110(9), P. 5585 - 5594
Published: June 14, 2024
Background:
Limited
studies
have
explored
the
joint
effect
of
physical
activity
(PA)
and
dietary
quality
(DQ)
on
mortality
outcomes
cancer
population.
The
authors
aim
to
investigate
separate
prognostic
PA
DQ
survival
US
survivors.
Methods:
Data
survivors
(
n
=3007,
representing
22
million
survivors)
were
from
National
Health
Nutrition
Examination
Survey
(NHANES)
between
2007
2018.
was
assessed
using
self-reported
Global
Physical
Activity
Questionnaire
(GPAQ)
evaluated
through
Eating
Index-2015
(HEI-2015).
Kaplan–Meier
(KM)
curves
Cox
proportional
hazard
model
used
evaluate
associations
effects
with
among
Results:
In
analyses,
sufficiently
active
(≥600
MET-min/week)
qualified
(≥60)
presented
reduced
risks
all-cause
(HR
0.45,
95%
CI:
0.35–0.59)
as
compared
each
lifestyle
intervention
separately.
Meanwhile,
either
insufficiently
or
(>0
associated
lower
for
0.60,
0.40–0.90)
noncancer
0.43,
0.32–0.59).
Conclusions:
Our
study
highlights
combination
strongly
risk
findings
might
help
refine
recommendations
this
Indian Journal of Community Medicine,
Journal Year:
2024,
Volume and Issue:
49(1), P. 120 - 130
Published: Jan. 1, 2024
Background:
In
the
past
two
decades,
growing
economy
associated
with
changes
in
lifestyle-related
behavior
is
partially
responsible
for
increasing
cancer
burden
India.
To
assess
occurrence
and
distribution
of
oral
based
on
analysis
hospital
records
from
registered
oncology
institutes
South
India
over
a
period
three
years.
Materials
Methods:
A
multicenter,
retrospective
study
was
conducted
at
seven
major
hospitals
to
incidence
among
patients
years
(2016–2018).
Data
were
collected
custom-made
validated
proforma.
Analysis
done
using
R
commander
software.
Results:
total
156090
various
types
cancers
reported
included
three-year
period,
an
almost
similar
gender
observed,
males
(n
=
78806,
42.99%
per
lakh)
compared
their
female
counterparts
77284,
42.16%
lakh).
Among
males’
lung
most
common
type
17709
cases
(9.65%
females,
breast
leading
22855
(12.46%
Over
years,
21084
malignancies
pertaining
cavity
identified
accounting
13.51%
cases.
cancers,
tongue
site
be
involved
44.22%
(2016–2018)
followed
by
buccal
mucosa
(14.69%),
least
lip
which
accounted
3.49%
Conclusion:
Breast
cancer.
Oral
occupied
second
fifth
rank
order
females.
Tongue
mucosa.
The
affected
lip.
