Oral Manifestations in Patients with COVID-19: A 6-Month Update

Journal of Dental Research, Journal Year: 2021, Volume and Issue: 100(12), P. 1321 - 1329

Published: July 29, 2021

This is the first update of previously published living systematic review that summarized evidence on prevalence oral signs and symptoms in patients with COVID-19. Hitherto, 183 studies were included, reporting data from 64,876 COVID-19 worldwide. The overall taste disorders was 38% (95% CI = 22% to 56%, I 2 98%). Hypogeusia, dysgeusia, ageusia also evaluated by a meta-analysis, pooled 34% for hypogeusia, 33% 26% ageusia. Taste associated positive test (odds ratio [OR] 7.54, 95% 5.24 10.86, 93%, P < 0.00001), showing high certainty evidence. However, association between mild/moderate severity (OR 1.63, 1.33 1.99, 69%, 0.0001) female 1.77, 1.26 2.48, 79%, 0.001) presented low Xerostomia new feature this update, demonstrated 43% 36% 50%, 71%) Regarding mucosal lesions, most common clinical pattern aphthous like, followed herpes-like candidiasis, glossitis/depapillation/geographic tongue, parotitis, angular cheilitis. Oral lesions more frequent lips, palate, presenting miscellaneous aspects are likely represent coinfections. Therefore, reanalysis current suggests triad xerostomia, dysfunction, as manifestations these outcomes under discussion, will be necessary confirm their direct SARS-CoV-2 infection cavity.

Language: Английский

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Characterization of dysphagia and laryngeal findings in COVID-19 patients treated in the ICU—An observational clinical study

PLoS ONE, Journal Year: 2021, Volume and Issue: 16(6), P. e0252347 - e0252347

Published: June 4, 2021

Background Dysphagia appears to be common in patients with severe COVID-19. Information about the characteristics of dysphagia and laryngeal findings COVID-19 treated intensive care unit (ICU) is still limited. Objectives The aim this study was evaluate oropharyngeal swallowing function appearance Method A series 25 ICU signs were examined fiberendoscopic evaluation (FEES) during latter stage or after discharge from ICU. Swallowing assessed standard rating scales video recordings. Results Pooling secretions found 92% patients. Eleven (44%) showed silent aspiration trachea on at least one occasion. All residue some degree both vallecula hypopharynx. Seventy-six percent had impaired vocal cord movement. Erythema folds 60% edema arytenoid region 60%. Conclusion Impairment abnormal To avoid complications related patient group, it seems great importance as a procedure, preferably an early stage, before initiation oral intake. Fiberendoscopic preferred due high incidence pooling secretion hypopharynx, aspiration, residuals. Further studies impact short- long-term are warranted.

Language: Английский

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Oral manifestations of COVID-19: Brief review

Dental and Medical Problems, Journal Year: 2021, Volume and Issue: 58(1), P. 123 - 126

Published: Feb. 16, 2021

The infection with a new type of virus -severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) -called disease 2019 (COVID-19) was first described in December 2019, Wuhan, China.Due to the gastrointestinal mucosa tropism virus, an attempt made describe oral manifestations SARS-CoV-2 infection.Angiotensin-converting enzyme (ACE2), which permits attachment is present also cavity.There are many symptoms cavity; among them, most prevalent ones dysgeusia (taste disorders), pain, exacerbation autoimmune diseases as well herpes simplex (HSV) and varicella zoster (VZV) infections.Ulcerations aphthous stomatitis often mentioned.The research shows that there COVID-19, but coexistence main has not been fully stated understood.There still no clearance on whether or occur due loss immune response.Therefore, further studies this subject should be conducted.

Language: Английский

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Oral Mucosa, Saliva, and COVID-19 Infection in Oral Health Care

Frontiers in Medicine, Journal Year: 2021, Volume and Issue: 8

Published: April 22, 2021

The SARS-CoV-2 virus has shaken the globe with an ongoing pandemic of COVID-19 and set challenges to every corner modern health care setting. oral mucosa saliva are high risk sites for higher viral loads dental professionals considered a group. COVID-19-induced lesions loss taste smell common clinical complaints in been found cause wide range non-specific mucosal lesions, but specific diagnosis these mucocutaneous as will facilitate prevention settings aid proper patient management. reported needs further investigation at receptor level it give new insights into pathogenicity. yield salivary secretion is finding this infection research focusing on developing rapid diagnostic fluid COVID-19. In review, we discuss significance mucosa, relevance dentistry.

Language: Английский

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Pathogenesis of taste impairment and salivary dysfunction in COVID-19 patients

Japanese Dental Science Review, Journal Year: 2021, Volume and Issue: 57, P. 111 - 122

Published: July 9, 2021

Coronavirus disease 2019 (COVID-19) is a highly transmissible pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The characteristics of the include broad range symptoms from mild to serious death, with pneumonia distress and complications in extrapulmonary organs. Taste impairment salivary dysfunction are common early COVID-19 patients. mouth significant entry route for SARS-COV-2, similar nose eyes. cells oral epithelium, taste buds, minor major glands express cell factors such as ACE2, TMPRSS2, Furin. We describe occurrence patients show immunohistochemical findings regarding tissue. review pathogeneses dysfunction. Treatment also described. Recently, it was reported that some people experience persistent prolonged dysfunction, described post-COVID-19 or long COVID-19, after illness infection has healed. To resolve these problems, important understand pathogenesis complications. advances have been understanding gustatory Although progress made, considerable effort still required in-depth elucidation pathogenesis.

Language: Английский

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SARS-CoV-2 Infection and Oral Health: Therapeutic Opportunities and Challenges

Journal of Clinical Medicine, Journal Year: 2021, Volume and Issue: 10(1), P. 156 - 156

Published: Jan. 5, 2021

The novel corona virus, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), and the disease it causes, COVID-19 (Coronavirus Disease-2019) have had multi-faceted effects on a number of lives global scale both directly indirectly. A growing body evidence suggest that patients experience several oral health problems such as dry mouth, mucosal blistering, mouth rash, lip necrosis, loss taste smell. Periodontal (PD), severe inflammatory gum disease, may worsen symptoms associated with COVID-19. Routine dental periodontal treatment help decrease PD is more prevalent among experiencing metabolic diseases obesity, diabetes mellitus cardiovascular risk. Studies shown these are highly susceptible for SARS-CoV-2 infection. Pro-inflammatory cytokines oxidative stress known to contribute development other elevated patients. determine severity Accumulating shows African-Americans (AAs) vulnerable populations disproportionately PD, compared ethnicities in United States. Dentistry healthcare professionals particularly this virus due transferability via cavity use aerosol creating instruments ubiquitous field. In review, we attempt provide comprehensive updated source information about SARS-CoV-2/COVID-19 various has profession visits clinics. Finally, review valuable resource management hygiene reduction

Language: Английский

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Oral health conditions and COVID-19: A systematic review and meta-analysis of the current evidence

Aging and Health Research, Journal Year: 2022, Volume and Issue: 2(1), P. 100064 - 100064

Published: March 1, 2022

The coronavirus disease 2019 (COVID-19) pandemic has highlighted the importance of understanding underlying conditions that lead to COVID-19. Oral health systemic implications in maintenance a healthy state. This study aimed summarize evidence on prevalence oral participants with COVID-19 and assess associations between related outcomes.

Language: Английский

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Prevalence of oral manifestations in COVID‐19: A systematic review

Reviews in Medical Virology, Journal Year: 2022, Volume and Issue: 32(6)

Published: March 10, 2022

Coronavirus disease 2019 (COVID-19) is a novel caused by newly identified virus Severe Acute Respiratory Syndrome 2 (SARS-CoV-2) causing diverse systemic manifestations. The oral cavity too not spared and the symptoms appear either independently, concurrently, or sequentially. In view of rising documented cases lesions COVID-19, this systematic review aims to assess prevalence manifestations in COVID-19 confirmed individuals. An extensive literature search was conducted databases like Scopus, Pubmed/Medline, Livivo, Lilacs Google Scholar varied signs were reported as per PRISMA guidelines. Studies published English language only included subjected risk bias using Joana Briggs Institute Appraisal tools for studies, case series reports. two-phase selection, 34 studies included: 21 observational, 3 case-series 10 These observational approximately 14,003 patients from countries. review, we explored most commonly encountered dental that loss taste acuity, xerostomia anosmia frequently reported. Elevated incidence opportunistic infections mucormycosis aspergillosis during treatment due prolonged intake steroids. Immunosuppression poor hygiene led secondary enanthematous lesions. However, it clear are infection itself result regimen followed [PROSPERO CRD42021258264].

Language: Английский

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Oral Manifestations of COVID-19 in Hospitalized Patients: A Systematic Review

International Journal of Environmental Research and Public Health, Journal Year: 2021, Volume and Issue: 18(23), P. 12511 - 12511

Published: Nov. 27, 2021

Background: COVID-19 disease first appeared in 2019 and quickly spread worldwide, causing a global pandemic. The oral cavity represents target of SARS-CoV-2, lesions are observed both non-hospitalized hospitalized patients. This systematic review aims to investigate the frequency manifestations Methods: An electronic search was conducted PubMed, Scopus, Web Science databases, including articles published up September 2021. protocol based on PRISMA-P. risk bias studies assessed using Joana Briggs Institute. certainty evidence GRADE instrument. Results: Fifty-nine were included: 19 case reports, 17 series, 2 case-control studies, 13 cross-sectional 4 observational retrospective studies. Oral ulcers, cheilitis, tongue more common patients before hospitalization, while perioral pressure macroglossia, blisters, candidiasis recurrent during hospitalization. could be related directly COVID-19, latter caused by medical devices, treatments, prone position, immunological impairment. Conclusions: accurate examination hospital admission all confirmed cases is encouraged recognize early apply appropriate treatments.

Language: Английский

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COVID-19 and Its Repercussions on Oral Health: A Review

Medicina, Journal Year: 2021, Volume and Issue: 57(11), P. 1189 - 1189

Published: Nov. 1, 2021

In 2019, a new type of coronavirus, SARS-CoV-2, the causing agent COVID-19, was first detected in Wuhan, China. On 11 March 2020, World Health Organization declared pandemic. The manifestations COVID-19 are mostly age-dependent and potentially more severe cases with involved co-morbidities. gravity symptoms depends on clinical stage infection. most common include runny nose nasal congestion, anosmia, dysgeusia or hypogeusia, diarrhea, nausea/vomiting, respiratory distress, fatigue, ocular symptoms, vomiting, abdominal pain. These systemic conditions often accompanied by skin mucosal lesions. Oral lesions reported patients include: herpex simplex, candidiasis, geographic tongue, aphthous-like ulcers, hemorrhagic ulcerations, necrotic white hairy reddish macules, erythematous surfaces, petechiae, pustular enanthema. It is still unclear if these direct result viral infection, consequence deterioration, adverse reactions to treatments. Poor oral hygiene hospitalized quarantined should also be considered as an aggravating condition. This narrative review focused presenting relevant data from literature regarding related well challenges faced dental system during this A routine intraoral examination recommended patients, either suspected confirmed, as, certain cases, represent sign infection even life-threatening our belief that extensive knowledge all possible manifestations, including lesions, great importance present uncertain context, new, currently emerging variants unknown future impact.

Language: Английский

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