Prevalence, Features and Degree of Association of Oral Lesions in COVID-19: A Systematic Review of Systematic Reviews

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(12), P. 7486 - 7486

Published: June 18, 2022

Regardless of rapidly emerging findings on oral lesions described in adult SARS-CoV-2-positive subjects, the evidence level remains quite low and rather contrasting; therefore, present systematic review reviews primarily aims to point out overall prevalence diagnosed cases. Secondary are estimate degree association between SARS-CoV-2 infection grade, based reported frequency, primary lesions, with related clinical presentations microscopic features, relation COVID-19 forms. A study protocol compliant PRISMA statement was developed. Twelve studies were included, reporting highly heterogeneous incomplete findings, thus precluding a meta-analysis. Further should be conducted assess cases among especially considering novel viral variants, determine their Moreover, noticed need evaluate putative role both genesis periodontitis periodontal microbiome worsening re-activations. Deeper insights into subjects could enhance comprehension illness pathogenesis, natural history presentation, improving preparedness health professionals inter-disciplinary management COVID-19.

Language: Английский

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Risk factors associated with severe dengue in Latin America: A systematic review and meta‐analysis

Tropical Medicine & International Health, Journal Year: 2024, Volume and Issue: 29(3), P. 173 - 191

Published: Jan. 23, 2024

Abstract Objective Severe dengue is a significant health problem in Latin America, with children being the most affected. Understanding risk factors for severe crucial enhancing patient care. Therefore, this study aims to systematically review literature identify associated America through systematic and meta‐analysis. Methods PubMed, SciELO, LILACS EMBASE databases were used search eligible scientific articles review. The outcomes considered symptoms of dengue, hospitalisation death. Joanna Briggs Institute Critical Appraisal Checklist was assess quality studies. Data analysis performed using STATA v 13.0 software. degree heterogeneity between studies quantified I 2 measure, statistically results defined as those p values <0.05. Results Of 1876 screened, 47 included 45 analysed Identified secondary infection, female sex, white or Caucasian ethnicity specific signs such headache, myalgia and/or arthralgia, vomiting/nausea, abdominal pain tenderness, diarrhoea, prostration, lethargy, fatigue similar. For death outcome, respiratory age <18 years identified factors. On other hand, women, diagnosis positive tourniquet test, platelet count <100,000 per μL capillary fragility lower probability These data highlight importance early screening patients, possible haemorrhagic reduce deaths from dengue. This has limitations, including publication bias, design biases. Conclusion findings are shaping strategies, management approaches identifying high‐risk groups, which will help establish future guidelines.

Language: Английский

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Oral Lesions Following Anti-SARS-CoV-2 Vaccination: A Systematic Review

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(16), P. 10228 - 10228

Published: Aug. 17, 2022

Increasing evidence relate anti-SARS-CoV-2 vaccinations to orofacial adverse reactions, therefore, the present systematic review aimed evaluate primary oral lesions diagnosed in adult subjects, following WHO Emergency Use Listing approved and EMA authorized vaccines, also relation cases' age, gender, comorbidities, history of COVID-19, vaccine type doses. The study protocol, registered on PROSPERO (CRD42022339032) compliant with PRISMA statement, included an electronic search across Scopus, MEDLINE/PubMed, BioMed Central databases, PROSPERO, ended 18 June 2022 succeeded by a manual search, independent data extraction, arisk bias evaluation through ROBINS-I tool. Qualitatively synthesized from 13studies showed overall low prevalence (16 cases), though higher females (68.8%), lesions, mainly erosions ulcers (34.5%). Nine cases were Pfizer-BioNTech, two Moderna, one AstraZeneca, Serum Institute India, Sinopharm, Johnson&Johnson respectively; specifically, eight after first dose seven second. In case, not specified. Considering newly developing presented findings may be updated further studies needed highlight factors affecting lesion occurrence specific macro-microscopic phenotypes vaccines' characteristics.

Language: Английский

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Oral Lesions in Pediatric Subjects: SARS-CoV-2 Infection and COVID-19 Vaccination

Applied Sciences, Journal Year: 2022, Volume and Issue: 12(18), P. 8995 - 8995

Published: Sept. 7, 2022

A plethora of systemic manifestations COVID-19 and adverse reactions to vaccines have been described in pediatric subjects. Therefore, the present systematic review primarily aimed assess prevalence macro-microscopic features oral lesions following SARS-CoV-2 infection, grading primary based on forms, The secondary aim was evaluate epidemiology, clinical appearance, histopathology WHO Emergency Use Listing approved EMA authorized vaccines, relation cases vaccine characteristics. study protocol compliant with PRISMA statement registered PROSPERO (CRD42022351821). Case reports, case series, observational studies were electronically searched till 27 July 2022, MEDLINE/PubMed, Scopus, Cochrane library databases, register. Data from nine describing viral infection two records reporting administration, evaluated through ROBINS-I tool for quality, independently extracted qualitatively synthesized, resulting scarce, jeopardized, incomplete findings. Since most rare recorded a part broad-spectrum disorders syndromes and, thus. undetailed or nonspecific, further should vaccination subjects, considering novel variants newly developing vaccines.

Language: Английский

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Dental Care and Education Facing Highly Transmissible SARS-CoV-2 Variants: Prospective Biosafety Setting: Prospective, Single-Arm, Single-Center Study

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(13), P. 7693 - 7693

Published: June 23, 2022

With the arrival of highly transmissible Omicron variants (BA.4 and BA.5), dentistry faces another seasonal challenge to preserve biosafety dental care education. aim protecting patients, students, teachers healthcare professionals, this paper introduces a prospective sustainable setting for everyday The developed by clinicians, epidemiologists, consists combination modern technologies focused on air-borne part viral pathway. introduced has been clinically evaluated after 18 months application in real clinical environment. protocol three fundamental pillars: (1) UVC air disinfection; (2) saturation with certified virucidal essences nebulizing diffusers; (3) complementary solutions including telehealth 3D printing. A pseudonymous online smart form was used as evaluation method. operates premise that everybody is hypothetical asymptomatic carrier. results 115 patient feedbacks imply no virus transmission from or doctor nurse observed reported using protocol, vice versa, although nine patients retrospectively admitted clinic visit likely be infectious. Despite these promising results, larger sample exposition current mutated strains are needed reliable conclusions about efficiency environments.

Language: Английский

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The oral manifestations and related mechanisms of COVID-19 caused by SARS-CoV-2 infection

Frontiers in Cellular Neuroscience, Journal Year: 2023, Volume and Issue: 16

Published: Jan. 4, 2023

Coronavirus disease 2019 (COVID-19) was reported to be associated with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, and patients present mostly symptoms. There have been an increasing number of reports on oral manifestations, some these signs are informative in terms identifying SARS-CoV-2 infection. The goal study review synthesize the clinical characteristics underlying mechanisms COVID-19 as well evaluate factors influencing infectivity, order conduct further in-depth investigations help clinicians diagnose exhibiting

Language: Английский

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Common Features in Compulsive Sexual Behavior, Substance Use Disorders, Personality, Temperament, and Attachment—A Narrative Review

International Journal of Environmental Research and Public Health, Journal Year: 2021, Volume and Issue: 19(1), P. 296 - 296

Published: Dec. 28, 2021

Do addictions share common traits of an "addictive personality" or do different have distinct personality profiles? This narrative review examines the differences in associations between substance use disorder (SUD) and compulsive sexual behavior (CSBD), on one hand, traits, attachment dispositions, temperament, other hand. We found that both people with a SUD CSBD tended to be more spontaneous, careless, less reliable, place self-interest above getting along others, show emotional instability experience negative emotions such as anger, anxiety, and/or depression, able control their attention behavior, engulfed constant sensation "wanting". Only CSBD, but not SUD, noted concerns social ties, fear losing close trusting others around them. Results also suggested high commonalities yet there are tendencies, especially others. People reported possible relationship losses compared issues, who may worried about source escapism.

Language: Английский

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Critical roles of cytokine storm and bacterial infection in patients with COVID-19: therapeutic potential of mesenchymal stem cells

Inflammopharmacology, Journal Year: 2023, Volume and Issue: 31(1), P. 171 - 206

Published: Jan. 4, 2023

Language: Английский

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COVID-19 and Related Vaccinations in Children: Pathogenic Aspects of Oral Lesions

Children, Journal Year: 2023, Volume and Issue: 10(5), P. 809 - 809

Published: April 29, 2023

Various clinical manifestations of SARS-CoV-2 infections and adverse reactions to COVID-19 vaccination have been described in children. The present narrative review aimed collect synthesize reported findings on oral lesions detected SARS-CoV-2-positive subjects following EMA-authorized WHO Emergency Use Listing-approved vaccine administration the pediatric population detail their features highlight possible pathogenic aspects those based current evidence. Few incomplete reports were retrieved from literature, probably because most belonged a broad spectrum systemic diseases syndromes nonspecific or inaccurately described. common patients erosive-ulcerative macules/petechiae, primarily erythematous. In context vaccination, rare typically presented as lesions, with EM-like unspecified patterns. Future studies should investigate after population, taking into account viral variants newly developed vaccines. Deeper insight detectable may increase clinicians' ability improve multidisciplinary general care.

Language: Английский

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Estimating the prevalence of oral manifestations in COVID-19 patients: a systematic review

Osong Public Health and Research Perspectives, Journal Year: 2023, Volume and Issue: 14(5), P. 388 - 417

Published: Oct. 4, 2023

Patients with coronavirus disease 2019 (COVID-19) present a variety of oral manifestations. Therefore, we conducted systematic review to estimate the prevalence lesions among COVID-19 patients.An extensive literature search several electronic bibliographic databases (PubMed, Scopus, Science Direct, Litcovid) was retrieve all articles published in English language from January 1, 2020 March 31, 2023 that reported manifestations patients. A meta-analysis pooled performed using Jamovi ver. 2.3 (2022). The I2 and Q statistics were used assess heterogeneity between studies, p-values <0.01 considered statistically significant.In total, 79 studies data 13,252 patients included. predominantly (n=33), Italy most common country (n=14). Most affected more than 50 years old women (56.6%). sites involvement tongue (n=65), followed by mucosa (n=37) lips (n=19). High found studies. manifestation taste alteration, xerostomia ulceration, showing rates 48%, 35%, 21%, respectively.COVID-19 show various may help clinicians identify promptly. Recognition signs symptoms is critical for an early diagnosis better prognosis.

Language: Английский

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