Advanced functional polymer materials for biomedical applications DOI Open Access

Refat El‐Sayed,

Yeit Haan Teow

Journal of Applied Polymer Science, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 27, 2024

Abstract Polymer structures are essential in biomedical applications due to their biocompatibility, biodegradability, and ability form intricate on micro‐ nanometer scales. This review, emphasizing electrospinning phase inversion techniques, examines the fabrication strategies chemical design of polymer for use. Electrospinning, particularly needleless electrospinning, produces nanofibres with high porosity flexibility is widely applied tissue engineering drug delivery. Phase inversion, including thermal, nonsolvent‐, vapor‐ evaporation‐induced separation, allows precise control over properties but faces challenges terms cooling rates solvent characteristics. Chemical through doping, functionalization, cross‐linking copolymerization enhances biodegradability mechanical polymers, facilitating advanced delivery, scaffolding biosensors. Advanced functional polymers revolutionizing fields, offering innovative solutions therapeutic medicine disease detection, diagnostics, regenerative medicine. Despite remarkable progress, challenges, such as scalability, cost‐effectiveness, environmental impact, persist. review underscores transformative potential materials medical treatments advocates continuous research interdisciplinary collaboration overcome existing fully exploit capabilities these improving patient care outcomes. Future perspectives highlight enhancing precision mechanisms, integrating other techniques developing large‐scale production methods advance field further.

Language: Английский

From Static to Dynamic: Smart Materials Pioneering Additive Manufacturing in Regenerative Medicine DOI Open Access
Antreas Kantaros, Theodore Ganetsos

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(21), P. 15748 - 15748

Published: Oct. 30, 2023

The emerging field of regenerative medicine holds immense promise for addressing complex tissue and organ regeneration challenges. Central to its advancement is the evolution additive manufacturing techniques, which have transcended static constructs embrace dynamic, biomimetic solutions. This manuscript explores pivotal role smart materials in this transformative journey, where are endowed with dynamic responsiveness biological cues environmental changes. By delving into innovative integration materials, such as shape memory polymers stimulus-responsive hydrogels, processes, research illuminates potential engineer unparalleled biomimicry. From dynamically adapting scaffolds that mimic mechanical behavior native tissues drug delivery systems respond physiological cues, convergence heralds a new era medicine. presents an insightful overview recent advancements, challenges, future prospects, underscoring pioneers shaping landscape heralding engineering propelled beyond towards biomimetic, responsive,

Language: Английский

Citations

52
4D Bioprinting: Keeping the Technology Alive DOI Creative Commons
Patrick Imrie, Jianyong Jin

Macromolecular Materials and Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 14, 2025

Abstract 4D bioprinting is a groundbreaking technology with potential to revolutionize healthcare. It based on additive manufacturing technologies, which are used fabricate dynamic prosthetics and devices from biologically compatible smart materials that respond stimuli. The ultimate end of the creation an artificial organ perfectly mimics functional movements native fully integrated within human body. In this perspective, two phases identified toward end. first minimally invasive surgery (MIS) using shape memory composites stimulated by near‐infrared (NIR) light and/or magnetic fields. second tissue engineering (DTE) activation biological

Language: Английский

Citations

2
Polymer/Graphene Nanocomposites via 3D and 4D Printing—Design and Technical Potential DOI Open Access
Ayesha Kausar, Ishaq Ahmad, Tingkai Zhao

et al.

Processes, Journal Year: 2023, Volume and Issue: 11(3), P. 868 - 868

Published: March 14, 2023

Graphene is an important nanocarbon nanofiller for polymeric matrices. The polymer–graphene nanocomposites, obtained through facile fabrication methods, possess significant electrical–thermal–mechanical and physical properties technical purposes. To overcome challenges of nanocomposite processing high performance, advanced strategies have been applied to design the next-generation materials–devices. This revolutionary review basically offers a fundamental sketch graphene, three-dimensional (3D) four-dimensional (4D) printing techniques. main focus article portray impact 3D 4D techniques in field nanocomposites. Polymeric matrices, such as polyamide, polycaprolactone, polyethylene, poly(lactic acid), etc. with processed using or technologies. employ various cutting-edge processes offer engineering opportunities meet manufacturing demands nanomaterials. methods used graphene nanocomposites include direct ink writing, selective laser sintering, stereolithography, fused deposition modeling other approaches. Thermally stable acid)–graphene oxide technique. 3D-printed poly(methyl methacrylate)–graphene printed stereolithography additive revealed enhanced morphological, mechanical biological properties. polyethylene–graphene by diffusion superior thermal conductivity, strength, modulus radiation- shielding features. number approaches, including modeling, etc., resulting unique honeycomb morphology, surface temperature, resistivity, glass transition temperature linear coefficient. has on acrylonitrile-butadiene-styrene, acid) thermosetting matrices nanofiller. Stereolithography-based 4D-printed nanomaterials complex shape-changing nanostructures having resolution. These materials stability performance applications. Consequently, 3D- applications relevance, photovoltaics, sensing, energy storage fields. In short, this paper reviewed background printing, graphene-based 3D–4D development technologies printing.

Language: Английский

Citations

33
Nature's Blueprint in Bioinspired Materials for Robotics DOI Open Access
Yeonwook Roh,

Youngseok Lee,

Daseul Lim

et al.

Advanced Functional Materials, Journal Year: 2023, Volume and Issue: 34(35)

Published: Aug. 22, 2023

Abstract Soft robotics, an emerging field that focuses on the development of robots utilizing soft, flexible, and deformable materials, is revolutionizing traditional robotics (reliant rigid materials motors) broadening its range applications potential uses. In addition, by emulating structure, function, characteristics biological systems, bioinspired are facilitating significant progress in a diverse array soft robotic applications. This review offers overview employed exploring their applications, challenges, future research directions. For intuitive understanding, based primary abilities required habitats (terrestrial, aquatic, aerial) animals plants they mimic categorized. Furthermore, real‐world developed everyday human life presented. The novel category classification comprehensive analysis presented this provide insights into systems with to transform various industries enhance quality life.

Language: Английский

Citations

24
Evolving Strategies and Materials for Scaffold Development in Regenerative Dentistry DOI Creative Commons
Michal Gašparovič, Petra Jungová, Juraj Tomášik

et al.

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(6), P. 2270 - 2270

Published: March 8, 2024

Regenerative dentistry has experienced remarkable advancement in recent years. The interdisciplinary discoveries stem cell applications and scaffold design fabrication, including novel techniques biomaterials, have demonstrated immense potential the field of tissue engineering regenerative therapy. Scaffolds play a pivotal role by facilitating regeneration restoring damaged or missing dental structures. These biocompatible biomimetic structures serve as temporary framework for cells to adhere, proliferate, differentiate into functional tissues. This review provides concise overview evolution strategies dentistry, along with analysis (Bard v2.0 based on Gemini neural network architecture) most commonly employed materials used fabrication during last 10 Additionally, it delves bioprinting, colonization procedures, outlines prospects regenerating whole tooth future. Moreover, discusses optimal conditions maximizing mesenchymal utilization optimizing personalization through precise 3D bioprinting. highlights advancements development, particularly advent bioprinting technologies, is comprehensive literature search influential publications this field.

Language: Английский

Citations

15
A Review of the Current State of Research and Future Prospectives on Stimulus-Responsive Shape Memory Polymer Composite and Its Blends DOI Open Access
Rajita Sanaka, Santosh Kumar Sahu, P.S. Rama Sreekanth

et al.

Journal of Composites Science, Journal Year: 2024, Volume and Issue: 8(8), P. 324 - 324

Published: Aug. 16, 2024

Shape-memory polymers (SMPs) possess unique properties that respond to external stimuli. The current review discusses types of SMPs, fabrication methods, and the characterization their mechanical, thermal, shape recovery properties. Research suggests SMP composites, when infused with fillers, demonstrate enhanced mechanical thermal characteristics. On other hand, blends, particularly incorporating polylactic acid (PLA), exhibit most efficient recovery. Furthermore, crosslinking density in polymer blends impacts force, showcasing a correlation between energy storage capacity force networks. Overall, show promising features, rendering them advantageous for applications artificial muscles, soft actuators, biomedical devices. This also future prospectives robust applications.

Language: Английский

Citations

12
4D fabrication of shape-changing systems for tissue engineering: state of the art and perspectives DOI Creative Commons
Lorenzo Bonetti, Giulia Scalet

Progress in Additive Manufacturing, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 12, 2024

Abstract In recent years, four-dimensional (4D) fabrication has emerged as a powerful technology capable of revolutionizing the field tissue engineering. This represents shift in perspective from traditional engineering approaches, which generally rely on static—or passive—structures (e.g., scaffolds, constructs) unable adapting to changes biological environments. contrast, 4D offers unprecedented possibility fabricating complex designs with spatiotemporal control over structure and function response environment stimuli, thus mimicking processes. this review, an overview state art for obtainment cellularized constructs is presented, focus shape-changing soft materials. First, approaches obtain are introduced, also describing conventional non-conventional techniques their relative advantages limitations. Next, main families materials, namely shape-memory polymers hydrogels discussed use described. Ultimately, current challenges proposed solutions outlined, valuable insights into future research directions provided disclose its full potential.

Language: Английский

Citations

9
Adaptive and intelligent polyurethane shape-memory polymers enabling next-generation biomedical platforms DOI Creative Commons

Tomy Muringayil Joseph,

Martin George Thomas, Debarshi Kar Mahapatra

et al.

Case Studies in Chemical and Environmental Engineering, Journal Year: 2025, Volume and Issue: unknown, P. 101165 - 101165

Published: Feb. 1, 2025

Language: Английский

Citations

2
Towards varying compositions PEO/PMMA/P(VDF-HFP) ternary polymer blend films for versatile flexible dielectrics over 20 Hz to 1GHz broadband device technologies DOI
R.J. Sengwa, Chandra Prabha Charan

Materials Today Communications, Journal Year: 2025, Volume and Issue: unknown, P. 112011 - 112011

Published: Feb. 1, 2025

Language: Английский

Citations

1
Carbon nanotube filled rubber nanocomposites DOI Creative Commons

Nimita K. C,

Jiji Abraham,

Martin George Thomas

et al.

Frontiers in Carbon, Journal Year: 2024, Volume and Issue: 3

Published: May 8, 2024

Rubber (elastomer) based polymer nanocomposites have attracted wide range of attention from industries and other fields due to its exceptionally good mechanical, thermal electrical properties. One the promising candidates this category is CNT filled rubber nanocomposites. This review throws light on historical trajectory development Various fabrication methods, detailed explanation reinforcement mechanism in CNT/rubber relationship between structure properties are reviewed. The next part discusses about morphological interface characteristics. An attempt investigate versatile thermal, also included review. final includes applications Major like electronics, sustainable biomedical EMI shielding discussed detail. focuses key challenges that arises while incorporating CNTs into matrices.

Language: Английский

Citations

8