Functionalized carbon nanotubes: synthesis, properties and applications in water purification, drug delivery, and material and biomedical sciences

Nanoscale Advances, Journal Year: 2021, Volume and Issue: 3(20), P. 5722 - 5744

Published: Jan. 1, 2021

Carbon nanotubes (CNTs) are considered as one of the ideal materials due to their high surface area, aspect ratio, and impressive material properties, such mechanical strength, thermal electrical conductivity, for manufacture next generation composite materials. In spite mentioned attractive features, they tend agglomerate inherent chemical structure which limits application. Surface modification is required overcome agglomeration increase dispersability leading enhanced interactions functionalized CNTs with matrix materials/polymer matrices. Recent developments concerning reliable methods functionalization carbon offer an additional thrust towards extending application areas. By functionalization, organic functional groups generated/attached surfaces well tip opens up possibilities tailoring properties Different research efforts have been devoted both covalent non-covalent different applications. Functionalized used successfully development quality nanocomposites, finding wide biological sensors, in optoelectronics catalysis. Non covalently a substrate immobilization large variety biomolecules impart specific recognition miniaturized biosensors designing novel bioactive nanomaterials. also demonstrated promising nanomaterials decontamination water adsorption capacity specificity various contaminants. Specifically modified utilized bone tissue engineering versatile drug delivery vehicle. This review article discusses short synthesis, applications CNTs. includes need CNTs, types especially respect biomedical sciences, purification, systems.

Language: Английский

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Applications of Metal-Organic Frameworks as Drug Delivery Systems

International Journal of Molecular Sciences, Journal Year: 2022, Volume and Issue: 23(8), P. 4458 - 4458

Published: April 18, 2022

In the last decade, metal organic frameworks (MOFs) have shown great prospective as new drug delivery systems (DDSs) due to their unique properties: these materials exhibit fascinating architectures, surfaces, composition, and a rich chemistry of compounds. The DSSs allow release active pharmaceutical ingredient accomplish desired therapeutic response. Over past few decades, there has been exponential growth many classes coordination polymers, MOFs gained popularity over other identified higher biocompatibility versatile loading capabilities. This review presents assesses most recent research, findings, challenges associated with use DDSs. Among commonly used for investigated-purpose MOFs, polymers complexes based on synthetic natural are well known. Specific attention is given stimuli- multistimuli-responsive MOFs-based Of interest in COVID-19 pandemic combination therapy multimodal systems.

Language: Английский

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Magnetically driven MWCNT-Fe3O4-water hybrid nanofluidic transport through a micro-wavy channel: A novel MEMS design for drug delivery application

Materials Today Communications, Journal Year: 2023, Volume and Issue: 38, P. 107844 - 107844

Published: Dec. 13, 2023

Language: Английский

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Innovative nanomaterials for cancer diagnosis, imaging, and therapy: Drug delivery applications

Journal of Drug Delivery Science and Technology, Journal Year: 2023, Volume and Issue: 82, P. 104357 - 104357

Published: March 12, 2023

Language: Английский

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Graphene-based materials for biotechnological and biomedical applications: Drug delivery, bioimaging and biosensing

Materials Today Chemistry, Journal Year: 2023, Volume and Issue: 33, P. 101750 - 101750

Published: Sept. 30, 2023

Language: Английский

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Cyclodextrin-Modified Nanomaterials for Drug Delivery: Classification and Advances in Controlled Release and Bioavailability

Pharmaceutics, Journal Year: 2021, Volume and Issue: 13(12), P. 2131 - 2131

Published: Dec. 10, 2021

In drug delivery, one widely used way of overcoming the biopharmaceutical problems present in several active pharmaceutical ingredients, such as poor aqueous solubility, early instability, and low bioavailability, is formation inclusion compounds with cyclodextrins (CD). recent years, use CD derivatives combination nanomaterials has shown to be a promising strategy for formulating new, optimized systems. The goals this review are give in-depth knowledge critical appraisal main CD-modified or CD-based lipid-based nanocarriers, natural synthetic polymeric nanosponges, graphene derivatives, mesoporous silica nanoparticles, plasmonic magnetic quantum dots other miscellaneous systems nanovalves, metal-organic frameworks, Janus nanofibers. Special attention given nanosystems that achieve controlled release increase their bioavailability during vivo studies.

Language: Английский

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Graphene Oxide–Protein-Based Scaffolds for Tissue Engineering: Recent Advances and Applications

Polymers, Journal Year: 2022, Volume and Issue: 14(5), P. 1032 - 1032

Published: March 4, 2022

The field of tissue engineering is constantly evolving as it aims to develop bioengineered and functional tissues organs for repair or replacement. Due their large surface area ability interact with proteins peptides, graphene oxides offer valuable physiochemical biological features biomedical applications have been successfully employed optimizing scaffold architectures a wide range organs, from the skin cardiac tissue. This review critically focuses on opportunities employ protein-graphene oxide structures either nanocomposites biocomplexes highlights effects carbonaceous nanostructures protein conformation structural stability in regenerative medicine. Herein, recent activity nanocomposite bioconjugates are analyzed respect cell viability proliferation, along these constructs sustain formation new Novel strategies approaches based stem therapy, well involvement extracellular matrix design smart nanoplatforms, discussed.

Language: Английский

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Metal‐based nanomaterials and nanocomposites as promising frontier in cancer chemotherapy

MedComm, Journal Year: 2023, Volume and Issue: 4(2)

Published: April 1, 2023

Abstract Cancer is a disease associated with complex pathology and one of the most prevalent leading reasons for mortality in world. Current chemotherapy has challenges cytotoxicity, selectivity, multidrug resistance, formation stemlike cells. Nanomaterials (NMs) have unique properties that make them useful various diagnostic therapeutic purposes cancer research. NMs can be engineered to target cells early detection deliver drugs directly cells, reducing side effects improving treatment efficacy. Several also used photothermal therapy destroy or enhance immune response by delivering immune‐stimulating molecules modulating tumor microenvironment. are being modified overcome issues, such as toxicity, lack increase drug capacity, bioavailability, wide spectrum therapies. To improve targeted delivery using nano‐carriers, noteworthy research required. metal‐based been studied expectation finding cure treatment. In this review, current development potential plant their on size shape discussed along more effective usage diagnosis

Language: Английский

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Graphene oxide/zinc ferrite nanocomposite loaded with doxorubicin as a potential theranostic mediu in cancer therapy and magnetic resonance imaging

Ceramics International, Journal Year: 2022, Volume and Issue: 48(8), P. 10741 - 10750

Published: Jan. 14, 2022

Language: Английский

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Application of Nanoparticles in Cancer Treatment: A Concise Review

Nanomaterials, Journal Year: 2023, Volume and Issue: 13(21), P. 2887 - 2887

Published: Oct. 31, 2023

Timely diagnosis and appropriate antitumoral treatments remain of utmost importance, since cancer remains a leading cause death worldwide. Within this context, nanotechnology offers specific benefits in terms therapy by reducing its adverse effects guiding drugs to selectively target cells. In comprehensive review, we have summarized the most relevant novel outcomes range 2010-2023, covering design application nanosystems for therapy. We established general requirements nanoparticles be used drug delivery strategies their uptake tumor microenvironment vasculature, including reticuloendothelial system surface functionalization with protein corona. After brief review classes nanovectors, covered different therapies. First, advances encapsulation (such as paclitaxel fisetin) into nanoliposomes nanoemulsions are described, well relevance current clinical trials. Then, polymeric presented, namely ones comprising poly lactic-co-glycolic acid, polyethylene glycol (and PEG dilemma) dendrimers. The quantum dots bioimaging is also covered, systems zinc sulfide indium phosphide. Afterwards, reviewed gold (spheres anisotropic) plasmon-induced photothermal iron oxide nanoparticles, such magnetite maghemite, has been analyzed fields, magnetic resonance imaging, immunotherapy, hyperthermia, delivery. Lastly, recent using carbon nanomaterials, graphene oxide, nanotubes, fullerenes, dots. Finally, compared passive active targeting theranostics. This aims (nano)mark on ongoing journey towards realizing remarkable potential realm therapeutics.

Language: Английский

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