Macromolecular Rapid Communications,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 20, 2025
Abstract
There
is
intense
research
during
the
past
few
decades
to
design
and
fabricate
drug
delivery
systems
using
electrospinning
system.
Electrospinning
an
efficient
technique
produce
nanofiber
materials
with
different
dimensions
morphologies
by
adjusting
processing
parameters.
becoming
innovative
technology
that
promotes
pursuit
maintenance
of
human
health.
Herein,
review
discusses
contribution
in
systems,
summarising
modification
various
system
configurations
effects
process
parameters
on
fibers,
their
application
including
carrier
materials,
loaded
drugs
release
mechanisms
illustrates
medical
applications.
Finally,
this
challenges,
bottlenecks,
development
prospects
field
terms
scaling
up
for
clinical
use
exploring
potential
solutions
pave
way
establish
future
systems.
Polymers,
Journal Year:
2024,
Volume and Issue:
16(2), P. 206 - 206
Published: Jan. 10, 2024
Degradable
polymers
(both
biomacromolecules
and
several
synthetic
polymers)
for
biomedical
applications
have
been
promising
very
much
in
the
recent
past
due
to
their
low
cost,
biocompatibility,
flexibility,
minimal
side
effects.
Here,
we
present
an
overview
with
updated
information
on
natural
degradable
where
a
brief
account
different
polysaccharides,
proteins,
viz.
polyesters/polyamino
acids/polyanhydrides/polyphosphazenes/polyurethanes
relevant
has
provided.
The
various
approaches
transformation
of
these
by
physical/chemical
means
cross-linking,
as
polyblends,
nanocomposites/hybrid
composites,
interpenetrating
complexes,
interpolymer/polyion
functionalization,
polymer
conjugates,
block
graft
copolymers,
are
described.
degradation
mechanism,
drug
loading
profiles,
toxicological
aspects
polymeric
nanoparticles
formed
also
defined.
Biomedical
polymer-based
biomaterials
wound
dressing/healing,
biosensors,
delivery
systems,
tissue
engineering,
regenerative
medicine,
etc.,
highlighted.
In
addition,
use
such
nano
systems
solve
current
problems
is
briefly
reviewed.
Journal of Nanobiotechnology,
Journal Year:
2024,
Volume and Issue:
22(1)
Published: April 27, 2024
Abstract
The
development
of
innovative
wound
dressing
materials
is
crucial
for
effective
care.
It’s
an
active
area
research
driven
by
a
better
understanding
chronic
pathogenesis.
Addressing
care
properly
clinical
challenge,
but
there
growing
demand
advancements
in
this
field.
synergy
medicinal
plants
and
nanotechnology
offers
promising
approach
to
expedite
the
healing
process
both
acute
wounds
facilitating
appropriate
progression
through
various
phases.
Metal
nanoparticles
play
increasingly
pivotal
role
promoting
efficient
preventing
secondary
bacterial
infections.
Their
small
size
high
surface
facilitate
enhanced
biological
interaction
penetration
at
site.
Specifically
designed
topical
drug
delivery,
these
enable
sustained
release
therapeutic
molecules,
such
as
growth
factors
antibiotics.
This
targeted
ensures
optimal
cell-to-cell
interactions,
proliferation,
vascularization,
fostering
controlled
healing.
Nanoscale
scaffolds
have
significant
attention
due
their
attractive
properties,
including
delivery
capacity,
porosity
area.
They
mimic
Extracellular
matrix
(ECM)
hence
biocompatible.
In
response
alarming
rise
antibiotic-resistant,
biohybrid
nanofibrous
dressings
are
gradually
replacing
conventional
antibiotic
systems.
emerging
class
comprises
biopolymeric
nanofibers
with
inherent
antibacterial
nature-derived
compounds,
biofunctional
agents.
Nanotechnology,
diminutive
nanomaterials,
nanoscaffolds,
nanofibers,
biomaterials
harnessed
aimed
review
article
discusses
effects
loaded
on
healing,
(in
vivo
vitro)
mechanical
outcomes.
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