Health benefits and health risks of contaminated fish consumption: Current research outputs, research approaches, and perspectives

Heliyon, Journal Year: 2024, Volume and Issue: 10(13), P. e33905 - e33905

Published: July 1, 2024

BackgroundFish contains high-quality omega-3 fatty acids, protein, vitamins, and minerals due to this it is termed as an essential component of a balanced diet. But there have been concerns raised about the risks consuming fish that contaminated with toxins such methylmercury, polychlorinated biphenyls (PCBs), dioxins, pesticides, plastic waste. Consumption containing these pollutants raising global mortality morbidity rates.Scope approachesThe review examines current research outputs on health benefits potential consumption. The also discusses various approaches mitigating problems caused by consumption, highlights roles balancing when fish.Key findings conclusionDifferent indicated contaminants cause cancer, kidney failure, adverse neurological effect, cardiovascular diseases, so vulnerable groups pregnant, child breast-feeding children. In conclusion, need get more tangible evidence advantages disadvantages consumption safeguard wellbeing society.

Language: Английский

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Food contaminants: Impact of food processing, challenges and mitigation strategies for food security

Food Research International, Journal Year: 2024, Volume and Issue: 191, P. 114739 - 114739

Published: July 6, 2024

Language: Английский

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Marine-Derived Compounds Applied in Cardiovascular Diseases: Submerged Medicinal Industry

Marine Drugs, Journal Year: 2023, Volume and Issue: 21(3), P. 193 - 193

Published: March 21, 2023

Cardiovascular diseases (CVDs) are among the most impactful illnesses globally. Currently, available therapeutic option has several side effects, including hypotension, bradycardia, arrhythmia, and alteration in different ion concentrations. Recently, bioactive compounds from natural sources, plants, microorganisms, marine creatures, have gained a lot of interest. Marine sources serve as reservoirs for new metabolites with various pharmacological activities. The marine-derived compound such omega-3 acid ethyl esters, xyloketal B, asperlin, saringosterol showed promising results CVDs. present review focuses on compounds’ cardioprotective potential hypertension, ischemic heart disease, myocardial infarction, atherosclerosis. In addition to alternatives, current use components, future trajectory, restrictions also reviewed.

Language: Английский

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Towards Lipid from Microalgae: Products, Biosynthesis, and Genetic Engineering

Life, Journal Year: 2024, Volume and Issue: 14(4), P. 447 - 447

Published: March 28, 2024

Microalgae can convert carbon dioxide into organic matter through photosynthesis. Thus, they are considered as an environment-friendly and efficient cell chassis for biologically active metabolites. Microalgal lipids a class of compounds that be used raw materials food, feed, cosmetics, healthcare products, bioenergy, etc., with tremendous potential commercialization. In this review, we summarized the commercial lipid products from eukaryotic microalgae, updated mechanisms synthesis in microalgae. Moreover, reviewed enhancement lipids, triglycerides, polyunsaturated fatty acids, pigments, terpenes microalgae via environmental induction and/or metabolic engineering past five years. Collectively, provided comprehensive overview biosynthesis, induced strategies genetic microalgal lipids. Meanwhile, outlook has been presented development industries, emphasizing significance accurate analysis bioactivity, well high-throughput screening specific

Language: Английский

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Bioactive Oxylipins Profile in Marine Microalgae

Marine Drugs, Journal Year: 2023, Volume and Issue: 21(3), P. 136 - 136

Published: Feb. 22, 2023

Microalgae are photosynthetic microscopic organisms that serve as the primary food source in aquatic environments. can synthesize a wide variety of molecules, such polyunsaturated fatty acids (PUFAs) omega-3 and omega-6 series. Oxidative degradation PUFA due to radical and/or enzymatic conversion leads formation oxylipins, which compounds known for their bioactive properties. In present study, we aim profile oxylipins from five microalgae species grown 10-L photo-bioreactors under optimal conditions. During exponential phase, were harvested, extracted analyzed by LC-MS/MS determine qualitative quantitative each species. The different selected revealed high diversity metabolites, up 33 non-enzymatic 24 concentrations. Taken together, these findings highlight an interesting role marine lipids mediators, hypothesize have important function preventive health measures amelioration inflammation. rich mixture may display advantages biological organisms, especially providing human benefits including antioxidant, anti-inflammatory, neuroprotective or immunomodulator activities. Some also well cardiovascular

Language: Английский

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‘Superfoods’: Reliability of the Information for Consumers Available on the Web

Foods, Journal Year: 2023, Volume and Issue: 12(3), P. 546 - 546

Published: Jan. 26, 2023

The term 'superfoods', used frequently with marketing purposes, is usually associated foodstuffs beneficial health properties. 'Superfoods' appears in many information sources, including digital media. they provide easily accessible for consumers through Internet search engines. objective of this work to investigate the data that web pages offer and their accuracy according current scientific knowledge. two main engines were utilized English language websites search, introducing 'superfoods'. In total, 124 results found. After applying selection criteria, 45 studied. A total 136 foods considered as 'superfoods' by sites; 10 them (kale, spinach, salmon, blueberries, avocado, chia, walnuts, beans, fermented milks garlic) mentioned on at least 15 sites. Nutritional healthy properties displayed sites compared information. conclusion, present a very simplified manner it generally not wrong. However, should comprehensible without raising false expectations regarding benefits. any case, consumption can have salutary effects part balanced diet.

Language: Английский

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Wine-Making; “with one Stone Two Birds”? A Holistic Review of the Bio-Functional Compounds, Applications and Health Benefits of Wine and Wineries’ By-Products

Published: June 14, 2023

The plethora of bio-functional compounds present in fermented alcoholic beverages like wine, as well the valorization bioactives from their wineries/breweries by-products grape pomace and seed, has gained significant interest functional foods sector. Wine always accompanied humanity, for religion or health. For example, Christians are using wine “Holy Communion”, following what Jesus Christ himself did said during Last Supper, while benefits consumption moderation was embedded all Mediterranean civilizations, it is mentioned by wise King-Prophet David his psalms, but also Hip-pocrates other men, a Greek-based philosophy “All things Moderation” (Cleobulus Lindos; 6th century BC). In modern times, after outbreak research on since 90’s, when term “French Paradox” introduced US public CBS show, recent evidence outlined that these derived synergisms its digestion-derived metabolites. Within this article, proposed health moderate consumption, component balanced diet (i.e. Mediterra-nean Diet), against inflammation-related chronic disorders, thoroughly reviewed. various both wineries’ by-products, such bioactive phe-nolics, unsaturated fatty acids, polar lipids, dietary fibers, antioxidant, anti-inflammatory antithrombotic promoting properties evaluated. mechanisms actions synergism, which elicited, ex-plored. Functional non-alcoholic products introduced. Emphasis given to applications bioactives, ingredients foods, supplements nutraceuticals. Limitations future perspectives popular beverage (wine) ant rich addressed. .

Language: Английский

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Functional foods

Elsevier eBooks, Journal Year: 2023, Volume and Issue: unknown, P. 367 - 377

Published: Jan. 1, 2023

Language: Английский

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Re-Assessing the Role of Platelet Activating Factor and Its Inflammatory Signaling and Inhibitors in Cancer and Anti-Cancer Strategies

Frontiers in Bioscience-Landmark, Journal Year: 2024, Volume and Issue: 29(10)

Published: Sept. 26, 2024

Since 2000s, we have outlined the multifaceted role of inflammation in several aspects cancer, via specific inflammatory mediators, including platelet activating factor (PAF) and PAF-receptor (PAFR) related signaling, which affect important junctions cellular interactions that are associated with tumor-related manifestations. It is now well established disease-related unresolved chronic responses can promote carcinogenesis. At same time, tumors themselves able to their progression metastasis, by triggering an inflammation-related vicious cycle, PAF its signaling play crucial role(s), usually conclude tumor growth angiogenesis. In parallel, new evidence suggests also interact cancer treatments inducing antitumor immune response or, conversely, promoting recurrence. Within this review article, current knowledge future perspectives implication all these thoroughly re-assessed. The potential beneficial PAF-inhibitors natural or synthetic modulators PAF-metabolism against tumors, metastasis evaluated. Emphasis given molecules dual anti-PAF anti-cancer activities (Bio-DAPAC-tives), proven potency through clinical trials, as on metal-based anti-inflammatory mediators constitute a class potent inhibitors. way compounds may anti-tumor effects modulate actions discussed. Limitations targeting PAF, metabolism receptor, PAF-related part(s) strategies involve response(s) for improved outcome,

Language: Английский

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Polyunsaturated Fatty Acids and Human Health: A Key to Modern Nutritional Balance in Association with Polyphenolic Compounds from Food Sources

Foods, Journal Year: 2024, Volume and Issue: 14(1), P. 46 - 46

Published: Dec. 27, 2024

Polyunsaturated fatty acids (PUFAs) are vital dietary elements that play a significant role in human nutrition. They highly regarded for their positive contributions to overall health and well-being. Beyond the fact they provide substantial supply of energy body (a saturated fats can also perform), these unsaturated and, especially, essential ones involved cell membrane structure, blood pressure regulation, coagulation; participate proper functioning immune system assimilation fat-soluble vitamins; influence synthesis pro- anti-inflammatory substances; protect cardiovascular system. Modern diets like Western diet American rich found especially fast food products, sweets, processed foods, has led an increase prevalence metabolic diseases worldwide (obesity, type II diabetes, gout, disease). Nutritionists have drawn attention moderate consumption need intake detriment ones. This paper examines biochemical roles polyunsaturated fats, particularly acids, contrasts benefits with detrimental effects fat overconsumption. Furthermore, it highlights necessity shifts towards increased PUFA mitigate global burden diet-related issues. The co-occurrence PUFAs polyphenols plant-based foods sophistication nature’s design. These bioactive compounds not randomly distributed but present humans consumed together historically. From traditional Mediterranean, which pairs olive oil (PUFAs polyphenols) vegetables legumes, Asian cuisines combining sesame seeds turmeric, cultural practices long harnessed this natural synergy.

Language: Английский

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