Research Square (Research Square),
Journal Year:
2023,
Volume and Issue:
unknown
Published: Dec. 14, 2023
Abstract
This
paper
extracts
alginate
of
Dictyota
mertensii
(DM),
brown
macroalgae
found
on
the
north
coast
northeastern
Brazil.
A
Composite
Central
Design
(CCD)
associated
with
Response
Surface
Methodology
(RSM)
was
employed
to
optimize
extraction
process
different
fractions
alginate,
in
conditions
time,
temperature,
and
concentration
Na2CO3.
Yield
(𝜂),
sulfate
content,
intrinsic
viscosity
([𝜂]),
viscosimetric
molar
mass
(Mv),
color
parameters
(a*,
b*
e
L*),
M/G
ratio
are
model
response
variables.
The
DM
algae
has
its
chemical
composition
expressed.
surfaces
plotted
from
variables
studied,
quadratic
models
were
predicted,
influence
factors
is
analyzed,
subjected
analysis
variance
(ANOVA)
F-test
at
95%
confidence.
antioxidant
potential
evaluated
based
scavenging
stable
free
radical
1,1-diphenyl-2-picrylhydrazyl
(DPPH).
maximum
yield
29.28±0.02
%,
content
ranged
3.50±0,00
%
12.33±0.29
%.
values
[𝜂]
Mv
5.84±0.06
dL.g-1
278.00±2.66
kDa,
respectively.
showed
a
dark
<1,
indicating
that
extracted
provides
rigid
compact
gels.
CI50
54.93±0.27%
0.51±0.07
mg.mL-1
,
respectively,
moderate
activity.
BMC Complementary Medicine and Therapies,
Journal Year:
2024,
Volume and Issue:
24(1)
Published: April 2, 2024
A
study
carried
out
by
World
Health
Organization
revealed
that
around
80%
of
individuals
globally
depends
on
herbal
forms
medication
with
40%
pharmaceutical
products
being
sourced
from
medicinal
plants.
The
objective
was
to
evaluate
the
phytochemicals
composition,
in
vitro
antimicrobial
and
antioxidant
properties
leaves
Terminalia
catappa
L.
aqueous
methanolic
extracts.
Journal of Medicinal Food,
Journal Year:
2024,
Volume and Issue:
27(2), P. 176 - 197
Published: Feb. 1, 2024
Obesity
and
its
comorbidities
represent
a
major
health
problem
worldwide.
Treatment
by
reducing
food
intake
physical
activity
interventions
has
limited
success
especially
with
elderly
people
chronic
diseases.
Nutraceuticals
are
naturally
originated
successfully
used
for
their
physiological
nutritional
benefit
in
care.
They
might
be
alternative
means
to
help
lose
weight
reduce
obesity-associated
metabolic
disorders
the
improvement
of
health,
delay
aging
process,
prevention
diseases,
increase
life
expectancy,
or
support
structure
function
body.
The
current
study
enumerates
inherent
role
nutraceuticals
management
obesity
related
comorbidities.
is
supported
molecular
docking
studies
discussing
mechanism
action.
An
attempt
optimize
made
this
article
addition
widen
scope
use
worldwide
disease.
Marine Drugs,
Journal Year:
2024,
Volume and Issue:
22(6), P. 273 - 273
Published: June 12, 2024
The
main
goal
of
this
study
was
to
assess
the
bioactive
and
polysaccharide
compositions,
along
with
antioxidant
antibacterial
potentials,
five
seaweeds
collected
from
northeastern
coast
Algeria.
Through
Fourier
transform
infrared
spectroscopy
analysis
X-ray
fluorescence
spectroscopy,
investigated
elemental
composition
these
their
chemical
structure.
In
addition,
compared
identified
biochemical
makeup
seaweed
by
using
cutting-edge
methods
like
tandem
mass
spectrometry
ultra-high-performance
liquid
chromatography,
it
searched
for
new
sources
nutritionally
valuable
compounds.
According
study’s
findings,
Sargassum
muticum
contains
highest
levels
extractable
compounds,
showing
a
phenolic
compound
content
235.67
±
1.13
µg
GAE·mg−1
total
sugar
46.43
0.12%
DW.
Both
S.
Dictyota
dichotoma
have
high
concentrations
good
polyphenols,
such
as
vanillin
chrysin.
Another
characteristic
that
sets
brown
algae
apart
is
composition.
It
showed
Cladophora
laetevirens
has
an
extracted
12.07%
capacity
scavenge
ABTS+
radicals
value
78.65
0.96
µg·mL−1,
indicating
activity.
terms
activity,
excellent
growth
inhibition.
conclusion,
all
species
under
investigation
exhibited
unique
strengths,
highlighting
variety
advantageous
characteristics
seaweeds,
especially
muticum.
BioMed Research International,
Journal Year:
2025,
Volume and Issue:
2025(1)
Published: Jan. 1, 2025
This
study
aims
to
assess
the
phytochemical
composition,
antioxidant
potential,
and
antidiabetic
properties
of
Erigeron
annuus
(L.)
Pers.
The
ethyl
acetate
fraction
leaves
exhibited
highest
extraction
rate
(22.42%).
preliminary
qualitative
analysis
in
crude
extract
fractions
is
often
performed
using
chemical
tests.
For
quantitative
analysis,
spectrophotometric
methods
are
widely
used
estimate
concentration
phytochemicals.
were
evaluated
2,2‐diphenyl‐1‐picrylhydrazyl
(DPPH)
radical
scavenging
assay
ferric
reducing
power
(FRAP)
assay,
which
measures
reduction
Fe
3+
2+
.
Qualitative
screening
revealed
presence
tannins,
flavonoids,
phenols,
saponins,
alkaloids.
Notably,
showed
significantly
(
p
<
0.05)
higher
total
phenolic
content
(70.01
±
1.1
mg/g)
flavonoid
(80.29
1.03
mg/g).
also
demonstrated
substantial
α
‐amylase
inhibitory
activity
suggesting
ability
polyphenols
reduce
activity.
inhibition
(23.15
1.22
%
67.31
2.01
)
IC
50
value
(40.59
0.03
μ
g/mL)
notably
compared
with
standard
drug
metformin
(19.88
1.51
g/mL).
glucose
levels
(10.88
1.29
65.11
0.94
conducted
a
lipid
peroxidation
experiment
utilizing
egg
yolk
as
source
lipids
high
content.
most
bioactive
was
for
cytotoxicity
against
HEK293
cell
line.
that
50%
viability
observed
at
g/mL,
indicating
plant
nontoxic
concentrations
below
this
threshold.
Furthermore,
dominant
further
investigated
liquid
chromatography–mass
spectroscopy
high‐performance
thin‐layer
chromatography
techniques
from
selected
plant.
Moreover,
an
vivo
will
be
evaluate
efficacy
,
isolate
characterize
its
components,
examine
molecular
mechanism
action
improve
therapeutic
applicability.
Botanica Marina,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 3, 2025
Abstract
The
present
study
elucidates
the
bioactive
metabolites,
antioxidants,
and
antibacterial
potential
of
selected
seaweeds
–
Kappaphycus
alvarezii
,
Caulerpa
chemnitzia
Sargassum
tenerrimum
collected
from
southwest
coast
India.
Biomolecules
were
extracted
using
six
solvents:
hexane,
dichloromethane,
ethyl
acetate,
acetone,
methanol,
ethanol.
Among
these,
ethanol
proved
to
be
most
efficient
extraction
solvent.
Notably,
ethanolic
extract
S
.
exhibited
high
phenolic
flavonoid
contents,
contributing
its
potent
antioxidant
properties.
In
contrast,
extracts
C
rich
in
tannins,
demonstrating
marked
activity.
Gas
Chromatography-Mass
Spectrometry
profiling
identified
approximately
42
compounds
with
antimicrobial,
antioxidant,
anticancer,
antidiabetic,
cardioprotective
Key
included
stigmasta-5,
24(28)-dien-3-ol
(3β,
24Z),
cholesterol
margarate,
arachidonic
acid,
squalene,
1-hexadecanol,
δ-tocopherol,
all
which
hold
significant
nutraceutical
cosmetic
value.
Furthermore,
susceptibility
tests
against
nine
bacterial
strains
revealed
that
K
was
particularly
effective
gram-positive
bacteria,
while
showed
considerable
efficacy
both
gram-negative
strains.
