From Ocean to Medicine: Harnessing Seaweed’s Potential for Drug Development

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(2), P. 797 - 797

Published: Jan. 8, 2024

Seaweed, a miscellaneous group of marine algae, has long been recognized for its rich nutritional composition and bioactive compounds, being considered nutraceutical ingredient. This revision delves into the promising role seaweed-derived nutrients as beneficial resource drug discovery innovative product development. Seaweeds are abundant sources essential vitamins, minerals, polysaccharides, polyphenols, unique secondary metabolites, which reveal wide range biological activities. These compounds possess potential therapeutic properties, making them intriguing candidates leads in various medical applications pharmaceutical It explores their pharmacological including antioxidant, anti-inflammatory, antimicrobial, anticancer activities, shedding light on agents. Moreover, manuscript provides insights development formulation strategies delivery systems to enhance bioavailability stability compounds. The also discusses challenges opportunities associated with integration seaweed-based industries. Regulatory considerations, sustainability, scalability sustainable seaweed sourcing cultivation methods addressed, emphasizing need holistic approach harnessing seaweed's potential. underscores immense valuable reservoir By bridging gap between biology, pharmacology, formulation, this research contributes critical advancement solutions sectors.

Language: Английский

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Seaweed: a sustainable solution for greening drug manufacturing in the pursuit of sustainable healthcare

Published: Feb. 27, 2024

The environmental impact of drug manufacturing raises concerns about sustainability in healthcare. To address this, exploring alternative approaches to production is crucial. This review focuses on seaweed as a sustainable resource for greening processes. Seaweed offers advantages such renewability, abundance, and positive footprint. begins by providing an overview practices the challenges faced achieving sustainability. It then discusses resource, including cultivation techniques benefits. has various applications manufacturing, extracting purifying bioactive compounds with potential therapeutic properties. Seaweed’s role developing green technologies, seaweed-based excipients, biodegradable packaging materials, source energy processes, highlighted. economic implications incorporating solutions are discussed, emphasizing reduced carbon footprint cost-effectiveness. Regulatory industrial perspectives addressed, examining challenges, opportunities implementing manufacturing. Collaboration between academia, industry, regulatory bodies crucial successful integration. presents future directions opportunities, emerging trends innovations areas further research, policy development, industry engagement recommendations. Incorporating into facilitates reduction impact, promotes efficiency, contributes showcases means foster greener addressing concerns, promoting

Language: Английский

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Recent advances in 3D bioprinted polysaccharide hydrogels for biomedical applications: A comprehensive review

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 348, P. 122845 - 122845

Published: Oct. 17, 2024

Polysaccharide hydrogels, which can mimic the natural extracellular matrix and possess appealing physicochemical biological characteristics, have emerged as significant bioinks for 3D bioprinting. They are highly promising applications in tissue engineering regenerative medicine because of their ability to enhance cell adhesion, proliferation, differentiation a manner akin cellular environment. This review comprehensively examines fabrication methods, polysaccharide hydrogel-driven bioprinting, underscoring its potential engineering, drug delivery, medicine. To contribute pertinent knowledge future research this field, critically key aspects, including chemistry carbohydrates, manufacturing techniques, formulation bioinks, characterization polysaccharide-based hydrogels. Furthermore, explores primary advancements 3D-printed encompassing delivery systems with controlled release kinetics targeted therapy, along tissue-engineered constructs bone, cartilage, skin, vascular regeneration. The use these bioprinted hydrogels innovative fields, disease modeling screening, is also addressed. Despite notable progress, challenges, modulating properties polysaccharides, enhancing bioink printability mechanical properties, achieving long-term vivo stability, been highlighted.

Language: Английский

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Biomedical potency and mechanisms of marine polysaccharides and oligosaccharides: A review

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 265, P. 131007 - 131007

Published: March 18, 2024

Derived from bountiful marine organisms (predominantly algae, fauna, and microorganisms), polysaccharides oligosaccharides are intricate macromolecules that play a significant role in the growth development of life. Recently, considerable attention has been paid to as auspicious natural products due their promising biological attributes. Herein, we provide an overview recent advances miscellaneous activities encompasses anti-cancer, anti-inflammatory, antibacterial, antiviral, antioxidant, anti-diabetes mellitus, anticoagulant properties. Furthermore, furnish concise summary underlying mechanisms governing behavior these macromolecules. We hope this review inspires research on medicinal applications while offering fresh perspectives broader facets.

Language: Английский

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Non-indigenous seaweeds in the Iberian Peninsula, Macaronesia Islands (Madeira, Azores, Canary Islands) and Balearic Islands: Biodiversity, ecological impact, invasion dynamics, and potential industrial applications

Algal Research, Journal Year: 2024, Volume and Issue: 78, P. 103407 - 103407

Published: Jan. 29, 2024

The term “non-indigenous species” (NIS) describes creatures that have colonized previously unoccupied parts of the globe. They enormous ecological and economic problems everywhere because their expanding presence. success biological invaders in this setting has recently been a hot topic. Of thousands marine NIS introduced all over world, seaweeds (marine macroalgae) are significant part. Global investigations conducted past ten years identified >277 species invasive seaweeds. More than 100 seaweed found Europe, northeastern Atlantic is especially renowned for harboring large number these species. main can currently be waters (Atlantic Mediterranean) Iberian Peninsula (including respective archipelagos) will topic revision, which examine processes invasion from introduction stage vectors to success. In order demonstrate how species, endangering ecosystem, an excellent environmental resource bioactive compounds with high industrial potential socioeconomic revenue, management as well uses biofertilizers, bioactivities, feed, food were also addressed.

Language: Английский

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Chemically modified seaweed polysaccharides: Improved functional and biological properties and prospective in food applications

Comprehensive Reviews in Food Science and Food Safety, Journal Year: 2024, Volume and Issue: 23(4)

Published: June 25, 2024

Abstract Seaweed polysaccharides are natural biomacromolecules with unique physicochemical properties (e.g., good gelling, emulsifying, and film‐forming properties) diverse biological activities anticoagulant, antioxidant, immunoregulatory, antitumor effects). Furthermore, they nontoxic, biocompatible biodegradable, abundant in resources. Therefore, have been widely utilized food, cosmetics, pharmaceutical industries. However, their bioactivities sometimes not satisfactory for some purposes. Modification of can impart the amphiphilicity new functions to biopolymers change structure conformation, thus effectively improving functional so as meet requirement targeted applications. This review outlined modification methods representative red algae (carrageenan agar), brown (fucoidan, alginate, laminaran), green (ulvan) that potential food applications, including etherification, esterification, degradation, sulfation, phosphorylation, selenylation, on. The improved modified seaweed applications also summarized.

Language: Английский

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Directed preparation of algal oligosaccharides with specific structures by algal polysaccharide degrading enzymes

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 277, P. 134093 - 134093

Published: July 23, 2024

Language: Английский

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Recent Advances in Edible Seaweeds: Ingredients of Functional Food Products, Potential Applications, and Food Safety Challenges

Food and Bioprocess Technology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 6, 2025

Language: Английский

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Carrageenan Modifications: Improving Biomedical Applications

Journal of Polymers and the Environment, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 7, 2025

Language: Английский

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Algae-Derived Natural Products in Diabetes and Its Complications—Current Advances and Future Prospects

Life, Journal Year: 2023, Volume and Issue: 13(9), P. 1831 - 1831

Published: Aug. 29, 2023

Diabetes poses a significant global health challenge, necessitating innovative therapeutic strategies. Natural products and their derivatives have emerged as promising candidates for diabetes management due to diverse compositions pharmacological effects. Algae, in particular, garnered attention potential source of bioactive compounds with anti-diabetic properties. This review offers comprehensive overview algae-derived natural management, highlighting recent developments future prospects. It underscores the pivotal role care delves into diversity algae, constituents, underlying mechanisms efficacy. Noteworthy algal substantial are briefly elucidated, along specific contributions addressing distinct aspects diabetes. The challenges limitations inherent utilizing algae interventions examined, accompanied by strategic recommendations optimizing effectiveness. By these considerations, this aims chart course research refining algae-based approaches. Leveraging multifaceted activities chemical components holds promise pursuit novel antidiabetic treatments. Through continued fine-tuning interventions, burden could be mitigated, ultimately leading enhanced patient outcomes.

Language: Английский

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