The Pharmacological Effects and Potential Applications of Limonene From Citrus Plants: A Review

Natural Product Communications, Journal Year: 2024, Volume and Issue: 19(5)

Published: May 1, 2024

The citrus plant is the general term for Citrus, Fortunella, and Poncirus, which includes oranges, tangerines, lemons, grapefruits, citrons. Not only does it contain a variety of delicious fruits, but also an important part traditional Chinese medicine. Citrus peels are rich in essential oils, primary active component limonene. Modern pharmacological research has revealed that limonene many effects, including antibacterial, anticancer, analgesic, immune regulation, neuroprotection, antioxidant, anti-inflammatory properties, treatment metabolic diseases. It finds widespread application industries, cosmetics, food, personal care, medicine, pesticides, others. This article reviews effects from plants to build scientific basis future lay groundwork developing functional foods prevention management linked disorders.

Language: Английский

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Green synthesis of zinc oxide nanoparticles using ethanolic extract of Gliricidia sepium (Jacq.) Kunth. ex. Walp., stem: Characterizations and their gastroprotective effect on ethanol-induced gastritis in rats

Bioorganic Chemistry, Journal Year: 2024, Volume and Issue: 145, P. 107225 - 107225

Published: Feb. 23, 2024

Language: Английский

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Protective effects of Euphorbia heterophylla against testicular degeneration in streptozotocin-induced diabetic rats in relation to phytochemical profile

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(1), P. e0314781 - e0314781

Published: Jan. 16, 2025

Background Diabetes mellitus (DM) poses a major risk to human health due an array of implications, one which is detrimental effect on the testicular and reproductive functions. Euphorbia heterophylla widely recognized for its medicinal properties worldwide. Methods findings The objective this study was profile E . ethanol extract (EH-EtOH) elucidate protective role in oxidative stress, relieving inflammatory action hyperglycemia-induced degeneration restoring normal histological structure with physiological tissue streptozotocin (STZ)-induced DM. High-resolution ultra-performance liquid chromatography-mass spectrometry (UHPLC-ESI-Orbitrap-MS) analysis employed analyze compounds present EH-EtOH. EH-EtOH against rat model DM evaluated by measuring improvements blood glucose levels, body weight, inflammation, damage, microcirculation impairment, apoptosis cells induced STZ. chemical profiling revealed presence 52 compounds, including phenolic acids, flavonoids, coumarins, phloroglucinols, triterpenes. Notably, identified isovitexin- C -hexoside, isorhamnetin- O diosmetin, halfordin first time species. Treatment effectively mitigated damage caused STZ, as evidenced restored testosterone (T4) levels antioxidant capacity, reduced expression pro-inflammatory cytokines, improved microcirculation, inhibition testes. Conclusions These results emphasize potential therapeutic related male infertility dysfunctions via antioxidant/angiogenetic /anti-apoptotic effect.

Language: Английский

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Comparative Study of Nutritional Composition, Physiological Indicators, and Genetic Diversity in Litopenaeus vannamei from Different Aquaculture Populations

Biology, Journal Year: 2024, Volume and Issue: 13(9), P. 722 - 722

Published: Sept. 14, 2024

This study aimed to evaluate the quality and genetic diversity of farmed Litopenaeus vannamei across three distinct populations from Maoming City (MM), Zhanjiang (ZJ), Yangjiang (YJ) in Guangdong Province. Muscle tissues L. were analyzed for phenotypic traits, conventional nutrients, amino acids, fatty while was assessed using whole genome sequencing techniques. The analysis revealed that crude protein content shrimp ranged 20.87 21.95 g/100 g, fat 0.90 1.50 essential acid 5.55 5.86 total 14.73 15.27 682.73 793.97 mg/100 antioxidant capacity (T-AOC) 2.68 2.72 μmol/g, superoxide dismutase (SOD) activity 1021.97 1057.21 U/g, catalase (CAT) 78.65 81.33 μmoL/min. No significant differences observed ash levels among nor biochemical indexes T-AOC, CAT, SOD. Genetic showed single nucleotide polymorphism density (SNP/Kb) 15.323 17.461, (π) 2.98 × 10−5 15.84 10−5, information (PIC) 0.300 0.317, heterozygosity (Ho) 0.033 0.048, inbreeding coefficients (FIS) 0.834 0.887. differentiation index (FST) values 0.056 0.106. provides an evaluation germplasm resources vannamei, offering insights efficient management sustainable utilization this species’ resources.

Language: Английский

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Comparative Analysis of Amino Acid Composition, Fatty Acid Profiles, and Genetic Diversity Among Three Populations of Penaeus semisulcatus

Journal of Marine Science and Engineering, Journal Year: 2025, Volume and Issue: 13(4), P. 655 - 655

Published: March 25, 2025

Penaeus semisulcatus, a commercially valuable aquaculture species, is widely distributed along the southeastern coast of China and throughout South Sea. Despite its economic importance, comprehensive understanding germplasm characteristics remains limited. This investigation evaluated nutrient profiles, amino acid composition, lipid constituents, antioxidant capacity, genomic variability across three farmed populations maintained under standardized environmental parameters to discern divergence in nutritive attributes hereditary characteristics. The results revealed significant interpopulation variation ash content (p < 0.05), while other proximate components showed comparable levels. Among 17 detected acids, glutamic was most abundant (2.07–2.30 g/100 g), cysteine had lowest concentration (0.10–0.11 g). Notably, PsHK population relatively higher content, indicating superior nutritional value. Fatty analysis 13 fatty with C18:0 (88.27–108.00 mg/100 g) being abundant, C20:2 (3.40–4.70 least. exhibited significantly levels all acids compared two 0.05). Antioxidant enzyme activity assays no differences capacity populations, similar overall status. Genetic diversity indicated that highest genetic diversity, pronounced differentiation between PsRP populations. In conclusion, comparative these cultured highlights excels both composition diversity. With profile rich background, P. semisulcatus shows great potential for development. These findings provide insights future improvement optimization efforts, offering scientific basis refining breeding strategies enhancing evaluation semisulcatus. Additionally, biochemical contributes better variation, which essential sustainable management utilization this species aquaculture.

Language: Английский

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A Comprehensive Assessment of the Nutritional Value, Antioxidant Potential, and Genetic Diversity of Fenneropenaeus merguiensis from Three Different Regions in China

Biology, Journal Year: 2024, Volume and Issue: 13(12), P. 1002 - 1002

Published: Dec. 2, 2024

Fenneropenaeus merguiensis is one of the largest species penaeid shrimp. It has a wide distribution germplasm resources in South China Sea and southeastern coastal regions China, yet its characteristics remain insufficiently understood. Therefore, we conducted analyses basic nutritional components, amino acids, fatty antioxidant indices, genetic diversity three F. populations (FmRP, FmSZ, FmSY). The results showed significant difference ash content, with FmSZ having highest content (1.77 g/100 g) (p < 0.05). A total 17 acids were detected, exhibited higher concentrations most especially essential analysis acid composition revealed differences between populations, FmSY potentially advantage overall In terms capacity diversity, there no (T-AOC), catalase (CAT), or superoxide dismutase (SOD) among > However, indicated that had lowest inbreeding coefficient relatively diversity. conclusion, quality high-quality aquatic product worth promoting. characterization various aspects from locations provide important information data support for breeding efforts.

Language: Английский

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Anisomeles indica (L.) Kuntze leaf essential oil ameliorates LPS-induced inflammation in RAW 264.7 cells: An integrated approach of network pharmacology and experimental validation

South African Journal of Botany, Journal Year: 2024, Volume and Issue: 169, P. 435 - 451

Published: May 4, 2024

Language: Английский

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Rosemary officinalis extract mitigates potassium dichromate-induced testicular degeneration in male rats: Insights from the Nrf2 and its target genes signaling pathway

Toxicology Reports, Journal Year: 2024, Volume and Issue: 13, P. 101700 - 101700

Published: July 24, 2024

This study aimed to investigate the protective effects of Rosemary ethanol extract (ROEE) on testicular damage induced by potassium Dichromate (PDC) in male rats regarding signaling pathway Nrf2 and its target genes proteins. A total 28 were divided into four groups: control, PDC only (15 mg/kg b.w. orally), + low dose ROEE (220 b.w.), high (440 b.w.). After days consecutive treatment, sacrificed for histological, immunohistochemistry, biochemical analyses. The results revealed that treatment up-regulated (NQO1, HO-1) mRNA expressions compared group. correspondingly, protein levels GCLM, GSH, SOD, catalase significantly increased ROEE-treated animals PDC-treated animals. Furthermore, administration led serum testosterone (T4) decreased estrogen (E2) Semen analysis histopathology demonstrated improved spermatological impairment caused PDC. immunoexpression cytoplasmic HSP-90 was reduced groups, while expression androgen receptor (AR) markedly improved. exhibited against PDC-induced damage, likely due antioxidant properties. However, further investigation is required elucidate underlying mechanisms action.

Language: Английский

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