Graphene and graphene oxide for bio-sensing: General properties and the effects of graphene ripples

Acta Biomaterialia, Journal Year: 2021, Volume and Issue: 131, P. 62 - 79

Published: July 5, 2021

The use of Graphene based materials, such as graphene oxide (GO), in biosensing applications is gaining significant interest, due to high signal output, with strong potential for industrial growth rate. Graphene's excellent conduction and mechanical properties (such toughness elasticity) coupled reactivity chemical molecules are some its appealing properties. presence ripples on the surface (whether indigenous or induced) represents another property/variable that provide enormous if harnessed properly. In this article, we review current knowledge regarding biosensing. We discuss briefly general topic using special emphasis wearable graphene-based biosensors. intrinsic their effect capabilities thoroughly discussed. dedicate a section also manipulation ripples. Then (GO) present biosensor devices made out GO detection different molecular targets. Finally, thoughts future perspectives opportunities field. STATEMENT OF SIGNIFICANCE: Biosensors tools detect amount substance, pregnancy tests glucose monitoring devices. They portable, have short response times sensitive, making them highly effective. Gold silver used biosensors more recently, graphene. sheets carbon atoms only two-dimensional crystal nature. It has unique features allowing effective applications, including (non-flat areas give it electronic properties). last comprehensive was published 2016. This paper reviews biosensors, focus capabilities.

Language: Английский

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Properties and application of carbon quantum dots (CQDs) in biosensors for disease detection: A comprehensive review

Journal of Drug Delivery Science and Technology, Journal Year: 2023, Volume and Issue: 80, P. 104156 - 104156

Published: Jan. 4, 2023

Language: Английский

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MXene–Graphene Field-Effect Transistor Sensing of Influenza Virus and SARS-CoV-2

ACS Omega, Journal Year: 2021, Volume and Issue: 6(10), P. 6643 - 6653

Published: March 2, 2021

An MXene–graphene field-effect transistor (FET) sensor for both influenza virus and 2019-nCoV sensing was developed characterized. The combines the high chemical sensitivity of MXene continuity large-area high-quality graphene to form an ultra-sensitive virus-sensing transduction material (VSTM). Through polymer linking, we are able utilize antibody–antigen binding achieve electrochemical signal when viruses deposited onto VSTM surface. integrated into a microfluidic channel that can directly receive in solution. tested with various concentrations antigens from two viruses: inactivated A (H1N1) HA ranging 125 250,000 copies/mL recombinant spike protein 1 fg/mL 10 pg/mL. average response time about ∼50 ms, which is significantly faster than existing real-time reverse transcription-polymerase chain reaction method (>3 h). low limit detection (125 protein) has demonstrated on FET platform sensing. Especially, signal-to-viral load ratio (∼10% change source-drain current gate voltage) also demonstrates ultra-sensitivity sensor. In addition, specificity by depositing channels opposite antibodies, producing differences times lower. Thus, have successfully fabricated relatively low-cost, ultrasensitive, fast-responding, specific VSTM.

Language: Английский

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Recent advances on rapid detection and remediation of environmental pollutants utilizing nanomaterials-based (bio)sensors

The Science of The Total Environment, Journal Year: 2022, Volume and Issue: 834, P. 155219 - 155219

Published: April 11, 2022

Language: Английский

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A critical review on multifunctional smart materials ‘nanographene’ emerging avenue: nano-imaging and biosensor applications

Critical reviews in solid state and materials sciences/CRC critical reviews in solid state and materials sciences, Journal Year: 2021, Volume and Issue: 47(5), P. 691 - 707

Published: June 14, 2021

Smart electronic materials ‘nanographene’ stated, its significant authentication has undergone massive improvements and emerged as a ‘material of the century’ in materialize fields ‘Chemical Biology’ ‘Materials Chemistry’. ‘Graphene’ wonder material been proposed to possess high surface area (∼2600 m2 g−1), portability charge carriers excellent mechanical qualities. Moreover, long-extend π-conjugation graphene is an essential photocatalytic property enabling wide ranging biosensor activities. Herein, critical review article reflects well known yet brand-new novel versatile integrations, utilized for substantial enrichment desired properties. Target cost-effectiveness, plasticity, environment-friendliness melt mixing/compounding fabrication strategy employed utilize in-vivo, in-vitro, in- situ, pharmaceutical, nano-imaging protocols. Owing nanographene’s range expansion, summarized latest breakthroughs Materials Science Biomedical utilizations including cancer nanotechnology, drug delivery, tissue manufacturing, scaffold, photo-thermal therapy, antimicrobial activities, made up exploring opportunities key challenges this emerging field.

Language: Английский

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Graphene and Graphene Oxide as a Support for Biomolecules in the Development of Biosensors

Nanotechnology Science and Applications, Journal Year: 2021, Volume and Issue: Volume 14, P. 197 - 220

Published: Nov. 1, 2021

Abstract: Graphene and graphene oxide have become the base of many advanced biosensors due to their exceptional characteristics. However, lack some properties, such as inertness in organic solutions non-electrical conductivity oxide, are drawbacks sensing applications. To compensate for these shortcomings, various methods modifications been developed provide appropriate properties required biosensing. Efficient modification facilitates interaction biomolecules with surface, ultimate bioconjugate can be employed main part biosensors. nanomaterials transducers increase signal response Their large surface area perfect biocompatibility lots prerequisite a stable biosensor, which is immobilization bioreceptor on transducer. Biosensor development has paramount importance field environmental monitoring, security, defense, food safety standards, clinical sector, marine biomedicine, drug discovery. applications also prevalent plant biology sector find missing links metabolic process. In this review, oxygen functional groups functionalizing different types functionalization will explained. Moreover, (such protein, peptide, DNA, aptamer) at end, application biomaterials transducing mechanisms discussed. Keywords: functionalization, immobilization, groups,

Language: Английский

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A Review of Graphene-Based Surface Plasmon Resonance and Surface-Enhanced Raman Scattering Biosensors: Current Status and Future Prospects

Nanomaterials, Journal Year: 2021, Volume and Issue: 11(1), P. 216 - 216

Published: Jan. 15, 2021

The surface plasmon resonance (SPR) biosensor has become a powerful analytical tool for investigating biomolecular interactions. There are several methods to excite plasmon, such as coupling with prisms, fiber optics, grating, nanoparticles, etc. challenge in developing this type of is increase its sensitivity. In relation this, graphene one the materials that widely studied because unique properties. studies, material been proven theoretically and experimentally sensitivity SPR. This paper discusses current development graphene-based SPR various excitation methods. discussion begins regarding properties general use biosensors. Simulation experimental results presented. Furthermore, expanded by providing review Surface-Enhanced Raman Scattering (SERS) provide an overview future.

Language: Английский

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Emerging Two‐Dimensional Tellurene and Tellurides for Broadband Photodetectors

Small, Journal Year: 2022, Volume and Issue: 18(20)

Published: March 4, 2022

Abstract As with all stylish 2D functional materials, tellurene and tellurides possessing excellent physical chemical properties such as high environmental stability, tunable narrow bandgap, lower thermal conductivity, have aroused the great interest of researchers. These materials also form basis for relatively newfangled scholarly fields involving advanced topics, especially broadband photodetectors. Integrating many tellurene/telluride‐based photodetectors show flexibility, higher frequency response or faster time response, signal‐to‐noise ratio, so on, which make them leading frontier photodetector research. To fully understand tellurene/tellurides their optoelectronic applications, recent advances in are maximally summarized. Benefiting from solid research this field, challenges opportunities future applications discussed review, might provide possibilities realization state‐of‐the‐art high‐performance devices.

Language: Английский

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Graphene-Based Electrochemical Biosensors for Breast Cancer Detection

Biosensors, Journal Year: 2023, Volume and Issue: 13(1), P. 80 - 80

Published: Jan. 3, 2023

Breast cancer (BC) is the most common in women, which also second public worldwide. When detected early, BC can be treated more easily and prevented from spreading beyond breast. In recent years, various biosensor strategies have been studied, including optical, electrical, electrochemical, mechanical biosensors. particular, high sensitivity short detection time of electrochemical biosensors make them suitable for recognition biomarkers. Moreover, increased by incorporating nanomaterials. this respect, outstanding electrical performances graphene led to an increasingly intense study graphene-based materials Hence, present review examines latest advances biosensing. For each biosensor, limit (LOD), linear range (LR), diagnosis technique are analyzed. This followed a discussion prospects current challenges, along with potential enhancing performance

Language: Английский

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Applications of nanomaterial technology in biosensing

Journal of Science Advanced Materials and Devices, Journal Year: 2024, Volume and Issue: 9(2), P. 100694 - 100694

Published: March 2, 2024

Nanomaterial technology is a comprehensive subject with strong intersections, and its related research content involves wide range of modern scientific technological fields. The science in the area nanomaterials has attracted attention many groups over past few years. By very nature, this topic lot room for research, to tiny objects nanometer range. Nanomaterials refer sudden changes properties substances when they reach scale, resulting special properties. In paper, we introduce various commonly used field biosensing, briefly explain advantages disadvantages nanoscale biosensors. At same time, also working principles types biosensors based on nanomaterial technology, including electrochemical biosensors, optical piezoelectric addition, sensing targets common such as enzymes, DNA, microorganisms, etc. Finally, discuss challenges prospects application analyze current trends future directions.

Language: Английский

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