The Importance of Nutrition in Menopause and Perimenopause—A Review

Nutrients, Journal Year: 2023, Volume and Issue: 16(1), P. 27 - 27

Published: Dec. 21, 2023

Menopause is associated with an increased prevalence of obesity, metabolic syndrome, cardiovascular diseases, and osteoporosis. These diseases unfavorable laboratory values, which are characteristic this period in women, can be significantly improved by eliminating reducing dietary risk factors. Changing habits during perimenopause most effectively achieved through nutrition counseling intervention. To reduce the factors all these case already existing disease, therapy led a dietitian should integral part treatment. The following review summarizes recommendations for balanced diet fluid intake, prevention role sleep, key preventive nutrients menopause, such as vitamin D, calcium, C, B vitamins, protein intake. In summary, many lifestyle developing (cardiovascular insulin resistance, type 2 diabetes mellitus, osteoporosis, tumors) symptoms period.

Language: Английский

---

B-Group Vitamins as Potential Prebiotic Candidates: Their Effects on the Human Gut Microbiome

Journal of Nutrition, Journal Year: 2024, Volume and Issue: 154(2), P. 341 - 353

Published: Jan. 3, 2024

Language: Английский

---

Circulating B vitamins metabolites in depressive disorders - connections with the microbiota-gut-brain axis

Behavioural Brain Research, Journal Year: 2024, Volume and Issue: 472, P. 115145 - 115145

Published: July 9, 2024

Language: Английский

---

Vitamin B6 Alleviates Aflatoxin B1-Induced Impairment of Testis Development by Activating the PI3K/Akt Signaling Pathway

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 29, 2025

Aflatoxin B1 (AFB1) is a harmful environmental contaminant known to disrupt gut microbiota and cause health problems. In recent years, the role of vitamin B6 (VB6) in maintaining intestinal reproductive has attracted much attention. AFB1 been found damage barrier inflammation by disrupting microbiota, particularly increasing abundance Enterococcus. mice treated with AFB1, serum metabolites were disturbed, VB6 levels reduced, testicular was exacerbated. Enterococcus exposure leads reduction levels, which accompanied damage. However, supplementation significantly ameliorated AFB1-induced injury. Transcriptomics Western blotting showed that after exposure, could increase expression phosphoinositide 3-kinase (PI3K) kinase B (AKT) as well their phosphorylated forms testes mice. Based on results, disturbing represents potential therapeutic counteract this conclusion, adequate can ameliorate damage, emphasizing importance intervention providing new perspective for prevention treatment AFB1-related issues.

Language: Английский

---

Gut Health and Influencing Factors in Pigs

Animals, Journal Year: 2023, Volume and Issue: 13(8), P. 1350 - 1350

Published: April 14, 2023

The gastrointestinal tract (GIT) is a complex, dynamic, and critical part of the body, which plays an important role in digestion absorption ingested nutrients excreting waste products digestion. In addition, GIT also vital preventing entry harmful substances potential pathogens into bloodstream. hosts significant number microbes, throughout their metabolites, directly interact with hosts. modern intensive animal farming, many factors can disrupt functions. As dietary biologically active play roles maintaining homeostasis eubiosis GIT, this review aims to summarize current status our knowledge on most areas.

Language: Английский

---

Whey - From waste to a valuable resource

Journal of Agriculture and Food Research, Journal Year: 2024, Volume and Issue: 18, P. 101280 - 101280

Published: July 4, 2024

Globally produced whey volume is estimated at more than 10 billion tons per year, and only 50 % of the total amount processed turned into products that are safe for environment. In addition, entering wastewater treatment plants leads to disruption facilities' operation further pollution environment, particularly water resources. contrast, main source protein contains other valuable components human organism. Therefore, our target was review recent studies analyse as a component from cheese factories its impact on processes resource processing. Review results indicated need individual highly concentrated streams containing alternative processing methods. The importance avoiding with stream redirecting it identified. Nevertheless, showed has high nutritional value by all indicators: energy (low-calorie product), biological (a wide range irreplaceable substances), physiological (provides comprehensive support most body systems anti-infective action), activity (rich content lactic acid bacteria). Further research possibilities fractional extraction whey's development technologies would allow complex dairy raw materials considered reasonable prospective current needs trends point view.

Language: Английский

---

Vitamin B, Role of Gut Microbiota and Gut Health

IntechOpen eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 24, 2024

The human gastrointestinal system is constantly exposed to pathogenic microorganisms and beneficial compounds, such as food components commensal bacteria. Vitamin B are a class of water-soluble organic compounds obtained through diet, supplementation, gut microbiota synthesis. vitamins absorbed for host metabolism in the small intestine, whereas microbes produce absorb large intestine. authors have accumulated evidence from various studies that each vitamin plays an essential role health has reciprocal relationship with microbiota. Previous also proven microbial imbalance lead competition utilization between microbes, affecting composition, health, metabolism. This review aims explain further types digestion, mechanism synthesis, composition tract. Thus, it can help practitioners consider administering maintain patient’s health.

Language: Английский

---

The altered metabolites contributed by dysbiosis of gut microbiota are associated with microbial translocation and immune activation during HIV infection

Frontiers in Immunology, Journal Year: 2023, Volume and Issue: 13

Published: Jan. 4, 2023

Background The immune activation caused by microbial translocation has been considered to be a major driver of HIV infection progression. dysbiosis gut microbiota demonstrated in infection, but the interplay between and its metabolites pathogenesis is seldom reported. Methods We conducted case-controlled study including 41 AIDS patients, 39 pre-AIDS patients 34 healthy controls. Both group were divided according clinical manifestations CD4 + T cell count. collected stool samples for 16S rDNA sequencing untargeted metabolomics analysis, examined blood samples. Results groups had higher levels activation. There significant differences at different stages infection. Higher abundances pathogenic bacteria or opportunistic pathogen, as well lower butyrate-producing with anti-inflammatory potential associated severity. metabolism tryptophan was disordered after Lower level phosphonoacetate, phenylethylamine polyamines observed And metabolic pathways related altered differed. Moreover, disrupted contributed found correlated Conclusions Metabolites function are translocation, suggesting that effect on intestinal barrier disruption

Language: Английский

---

Gut microbiome responds compositionally and functionally to the seasonal diet variations in wild gibbons

npj Biofilms and Microbiomes, Journal Year: 2023, Volume and Issue: 9(1)

Published: April 21, 2023

Abstract Wild animals may encounter multiple challenges especially food shortage and altered diet composition in their suboptimal ranges. Yet, how the gut microbiome responds to dietary changes remains poorly understood. Prior studies on wild animal microbiomes have typically leaned upon relatively coarse records individually unresolved fecal samples. Here, we conducted a longitudinal study integrating 514 time-series recognized samples with parallel fine-grained data from two Skywalker hoolock gibbon ( Hoolock tianxing ) groups populating high-altitude mountainous forests western Yunnan Province, China. 16S rRNA gene amplicon sequencing showed remarkable seasonal fluctuation gibbons’ microbial community structure both across individuals between social groups, driven by relative abundances of Lanchnospiraceae Oscillospiraceae associated fluctuating consumption leaf. Metagenomic functional profiling revealed that diverse metabolisms cellulose degradation short-chain fatty acids (SCFAs) production were enriched high-leaf periods possibly compensate for energy intake. Genome-resolved metagenomics further enabled resolving metabolic capacities carbohydrate breakdown among members which exhibited high degree redundancy. Our results highlight taxonomically functionally sensitive actively responding seasonally shifting diet, facilitating survival reproduction endangered species habitats.

Language: Английский

---

Green Pea (Pisum sativum L.) Hull Polyphenol Extract Alleviates NAFLD through VB6/TLR4/NF-κB and PPAR Pathways

Journal of Agricultural and Food Chemistry, Journal Year: 2023, Volume and Issue: 71(43), P. 16067 - 16078

Published: Oct. 20, 2023

Green pea hull is a processing byproduct of green and rich in polyphenols. Nonalcoholic fatty liver disease (NAFLD) chronic metabolic characterized by accumulation lipids the for which there are no effective treatment strategies. Here, mouse model NAFLD induced DSS+high-fat diet (HFD) was established to investigate effect polyphenol extract (EGPH). The results show that EGPH relief combined effect, including reducing hepatic fat accumulation, improving antioxidant activity blood lipid metabolism, maintaining glucose homeostasis. Increased intestinal permeability aggravated NAFLD. Combined metabolomics transcriptomic analysis showed vitamin B6 key target substance alleviate NAFLD, it may be flora metabolite. After intervention, level mice significantly increased, more than 60% enters liver, activated or inhibited PPAR TLR4/NF-κB signaling pathways relieve Our research could win–win expanding use search prophylactic drugs.

Language: Английский

---