Role of Humic Substances in the (Bio)Degradation of Synthetic Polymers under Environmental Conditions DOI Creative Commons

Olga Senko,

Olga Maslova, Nikolay Stepanov

et al.

Microorganisms, Journal Year: 2024, Volume and Issue: 12(10), P. 2024 - 2024

Published: Oct. 6, 2024

Information on the detection of presence and potential for degradation synthetic polymers (SPs) under various environmental conditions is increasing interest concern to a wide range specialists. At this stage, there need understand relationship between main participants in processes (bio)degradation SPs ecosystems (reservoirs with fresh sea water, soils, etc.), namely themselves, cells microorganisms (MOs) participating their degradation, humic substances (HSs). HSs constitute macrocomponent natural non-living organic matter aquatic soil ecosystems, formed transformed mineralization bio-organic conditions. Analysis mechanisms influence each other effects produced that accelerate or inhibit polymer can create basis scientifically based approaches most effective solution problem SPs, including form microplastics. This review aimed at comparing aspects interactions MOs, laboratory experiments (in vitro) investigations situ) biodegradation polymers, as well pollutants (antibiotics pesticides) they absorb. Comparative calculations velocity different environments are presented. A special place analysis given elemental chemical composition HSs, which successfully involved SPs. In addition, role photo-oxidation photoaging ultraviolet spectrum solar radiation discussed.

Language: Английский

Using Fungi in Artificial Microbial Consortia to Solve Bioremediation Problems DOI Creative Commons
Елена Ефременко, Nikolay Stepanov,

Olga Senko

et al.

Microorganisms, Journal Year: 2024, Volume and Issue: 12(3), P. 470 - 470

Published: Feb. 26, 2024

There is currently growing interest in the creation of artificial microbial consortia, especially field developing and applying various bioremediation processes. Heavy metals, dyes, synthetic polymers (microplastics), pesticides, polycyclic aromatic hydrocarbons pharmaceutical agents are among pollutants that have been mainly targeted by based on consortia containing fungi (mycelial types yeasts). Such can be designed both for treatment soil water. This review aimed at analyzing recent achievements research useful environmental technologies, where fungal cells applied. The main tendencies formation certain combinations, preferences their forms usage (suspended or immobilized), evaluated using current publications, place genetically modified with assessed. effect multicomponence estimated, as well influence this factor functioning efficiency pollutant removal efficacy. conclusions development new mixed biocatalysts eco-compatible remediation processes implement cells.

Language: Английский

Citations

5

Quorum sensing: cell-to-cell communication in Saccharomyces cerevisiae DOI Creative Commons
Linbo Li,

Yuru Pan,

Shishuang Zhang

et al.

Frontiers in Microbiology, Journal Year: 2023, Volume and Issue: 14

Published: Nov. 23, 2023

Quorum sensing (QS) is one of the most well-studied cell-to-cell communication mechanisms in microorganisms. This intercellular process Saccharomyces cerevisiae began to attract more and attention for researchers since 2006, phenylethanol, tryptophol, tyrosol have been proven be main quorum molecules (QSMs) S. . In this paper, research history hotspots QS are reviewed, particular, system introduced from aspects regulation mechanism QSMs synthesis, influencing factors production, response QSMs. Finally, employment adaptation stress, fermentation products increasing, food preservation was reviewed. review will useful investigating microbial interactions , helpful which yeast participates, provide an important reference future on QS.

Language: Английский

Citations

12

Transcriptomic responses of the microalgae, Scenedesmus sp. KT-U in vegetable waste media: An insight into gene and metabolic pathway regulation reveal the adaptation to biowaste DOI
Rathinasamy Karpagam,

Saranya Nallusamy,

E. Kokiladevi

et al.

Journal of Water Process Engineering, Journal Year: 2025, Volume and Issue: 71, P. 107095 - 107095

Published: Feb. 21, 2025

Language: Английский

Citations

0

Metal Nanomaterials and Hydrolytic Enzyme-Based Formulations for Improved Antifungal Activity DOI Open Access
Ilya Lyagin, Aysel Aslanli, Maksim Domnin

et al.

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(14), P. 11359 - 11359

Published: July 12, 2023

Active research of metal-containing compounds and enzymes as effective antifungal agents is currently being conducted due to the growing resistance problem. Metals are attracting special attention wide variety ligands that can be used for them, including chemically synthesized naturally obtained variants a result so-called "green synthesis". The main mechanism action metals triggering generation accumulation reactive oxygen species (ROS). Further ROS on various biomolecules nonspecific. Various hydrolytic (glucanases proteases), in turn, exhibit properties by affecting structural elements fungal cells (cell walls, membranes), quorum sensing molecules, own protective (mycotoxins antibiotics), proteins responsible adhesion formation stable, highly concentrated populations form biofilms. A substrate range allows use mechanisms their actions. In this review, we discuss prospects combining two different types (metals enzymes) against mycelial fungi yeast cells. Special paid possible influence activity effects compounds.

Language: Английский

Citations

8

BIOCATALYSIS IN DEGRADATION OF SYNTHETIC POLYMERS DOI Open Access
Olga Maslova,

Olga Senko,

Nikolay N. Stepanov

et al.

Lomonosov chemistry journal, Journal Year: 2024, Volume and Issue: 65(№2, 2024), P. 161 - 168

Published: Feb. 26, 2024

Waste from the production and use of synthetic polymers is a serious problem. The development application enzymatic microbial biocatalysts capable degrading hard-to-decompose seems to be one promising environmentally oriented solutions this possibilities combining (enzymes, cells) with metal catalysts are considered as perspective basis for new hybrid chemical-biocatalytic processes designed effective degradation polymers.

Language: Английский

Citations

1

Biocatalysis in the Degradation of Synthetic Polymers DOI
Olga Maslova,

Olga Senko,

Nikolay Stepanov

et al.

Moscow University Chemistry Bulletin, Journal Year: 2024, Volume and Issue: 79(2), P. 140 - 145

Published: April 1, 2024

Language: Английский

Citations

1

“Stop, Little Pot” as the Motto of Suppressive Management of Various Microbial Consortia DOI Creative Commons
Елена Ефременко, Nikolay Stepanov,

Olga Senko

et al.

Microorganisms, Journal Year: 2024, Volume and Issue: 12(8), P. 1650 - 1650

Published: Aug. 12, 2024

The unresolved challenges in the development of highly efficient, stable and controlled synthetic microbial consortia, as well use natural are very attractive for science technology. However, consortia management should be done with knowledge how not only to accelerate but also stop action such "little pots". Moreover, there a lot activity which suppressively controlled. processes, catalyzed by various microorganisms being complex slowed down or completely cancelled, typical environment (biocorrosion, landfill gas accumulation, biodegradation building materials, water sources deterioration etc.), industry (food biotechnological production), medical practice (vaginitis, cystitis, intestinal dysbiosis, etc.). search ways suppress functioning heterogeneous each these areas is relevant. purpose this review summarize general trends studies regarding targets new means influence used. analysis features applied approaches solving main problem confirms possibility obtaining combined effect, selective on individual components consortia. Of particular interest role viruses suppressing different compositions.

Language: Английский

Citations

1

Artificial Humic Substances as Biomimetics of Natural Analogues: Production, Characteristics and Preferences Regarding Their Use DOI Creative Commons
Елена Ефременко, Nikolay Stepanov,

Olga Senko

et al.

Biomimetics, Journal Year: 2023, Volume and Issue: 8(8), P. 613 - 613

Published: Dec. 15, 2023

Various processes designed for the humification (HF) of animal husbandry wastes, primarily bird droppings, reduce their volumes, solve environmental problems, and make it possible to obtain products with artificially formed humic substances (HSs) as analogues natural HSs, usually extracted from fossil sources (coal peat). This review studies main characteristics various biological physicochemical methods HF wastes (composting, anaerobic digestion, pyrolysis, hydrothermal carbonation, acid or alkaline hydrolysis, subcritical water extraction). A comparative analysis rates HS yields in these processes, resulting artificial HSs (humification index, polymerization degree aromaticity, etc.) was carried out. The factors (additives, process conditions, waste pretreatment, that can increase efficiency affect properties are highlighted. Based on results chemical composition analysis, trends preferences regard use complex biomimetics discussed.

Language: Английский

Citations

3

Enhanced polysaccharide production through quorum sensing system in Cordyceps militaris DOI
Qiao Huang,

Jianshu Chen,

Shengli Yang

et al.

Journal of Basic Microbiology, Journal Year: 2024, Volume and Issue: 64(7)

Published: May 21, 2024

This study aimed to enhance extracellular polysaccharide (EPS) production in Cordyceps militaris by constructing a quorum sensing (QS) system regulate the expression of biosynthetic enzyme genes, including phosphoglucomutase, hexokinase, phosphomannomutase, synthase, and UDP-glucose 4-epimerase genes. The found higher EPS concentrations seven recombinant strains compared wild-type C. militaris, indicating that overexpression key genes increased production. Among them, CM-pgm-2 strain exhibited highest production, reaching concentration 3.82 ± 0.26 g/L, which was 1.52 times than amount produced wild strain. Additionally, regulatory effects aromatic amino acids on QS were investigated. Under influence 45 mg/L tryptophan, reached 4.75 0.20 representing 1.90-fold increase strains. provided an effective method for large-scale EPSs opened up new avenues research into fungal mechanisms.

Language: Английский

Citations

0

Enzymes in the Content of Combined Antimicrobials as Improvers of Their Action DOI Creative Commons
Nikolay Stepanov, Aysel Aslanli, Maksim Domnin

et al.

Journal of NBC Protection Corps, Journal Year: 2024, Volume and Issue: 8(2), P. 146 - 163

Published: Sept. 4, 2024

Accumulating information about the growing number of microorganisms that are resistant to antibiotics used, on one hand, and emergence presence laboratories in which closed work is carried out with microbial pathogens, negative properties can be artificially enhanced. The aim analyze current trends development antimicrobial drugs combining use wellknown widely used antibiotics, as well substances properties, including metal nanoparticles, peptides, various enzymes allow preserve enhance effect against cells source base research mainly English–language scientific literature available via global Internet network, authors’ own published experimental studies. method analytical. Results. considers that, unlike classical agents, more often enter into reactions inhibiting key biochemical reactions, catalysts for processes aimed at oxidation hydrolysis molecules metabolically structurally important microorganisms. Conclusion. enzyme repeatedly enters significantly reduce concentrations vital activity cells, leads their weakening effective action agents. Most often, this case, themselves act carriers action, avoids non-specific interaction other, primarily proteins, thus removing some, example, from active pathogen cells. It has been demonstrated enzymatic enhancement bactericidal agents relation different complex biosystems (biofilms) formed by them, both several times orders magnitude. Such combined may interest carrying sanitary treatments surfaces, containers, premises, biological laboratories, introduction protective dressing materials.

Language: Английский

Citations

0