Antibiotic use and adherence to the WHO AWaRe guidelines across 16 hospitals in Zambia: a point prevalence survey
JAC-Antimicrobial Resistance,
Journal Year:
2024,
Volume and Issue:
6(5)
Published: Sept. 3, 2024
The
inappropriate
use
of
antibiotics
in
hospitals
contributes
to
the
development
and
spread
antimicrobial
resistance
(AMR).
This
study
evaluated
prevalence
antibiotic
adherence
World
Health
Organization
(WHO)
Access,
Watch
Reserve
(AWaRe)
classification
across
16
Zambia.
Language: Английский
The Burden of Antimicrobial Resistance in Zambia, a Sub-Saharan African Country: A One Health Review of the Current Situation, Risk Factors, and Solutions
Pharmacology & Pharmacy,
Journal Year:
2024,
Volume and Issue:
15(12), P. 403 - 465
Published: Jan. 1, 2024
Language: Английский
Point Prevalence Survey of Antibiotic Use in Level 1 hospitals in Zambia: Future Prospects for Antimicrobial Stewardship Programs
Infection and Drug Resistance,
Journal Year:
2025,
Volume and Issue:
Volume 18, P. 887 - 902
Published: Feb. 1, 2025
The
inappropriate
prescribing
and
use
of
antibiotics
have
contributed
to
the
emergence
spread
antimicrobial
resistance
(AMR).
In
Zambia,
there
is
a
paucity
information
on
patterns
among
hospitalized
patients
in
level
1
hospitals.
This
study
investigated
antibiotic
five
hospitals
Lusaka,
Zambia.
cross-sectional
utilized
World
Health
Organization
(WHO)
Point
Prevalence
Survey
(PPS)
methodology
in-patients
admitted
before
08:00
a.m.
survey
day
August
2024.
Data
were
analysed
using
IBM
SPSS
version
23.0.
prevalence
inpatients
was
59.0%,
with
ceftriaxone
being
most
prescribed.
Antibiotics
prescribed
mainly
for
paediatrics
male
inpatients.
found
that
53.0%
from
Access
group
while
38.2%
Watch
Access,
Watch,
Reserve
(AWaRe)
classification.
Adherence
national
treatment
guidelines
36.0%,
empirically
without
evidence
culture
sensitivity
tests.
high
low
adherence
findings
this
demonstrate
need
establish
strengthen
stewardship
programs
laboratory
capacity
aid
clinicians
diagnosing,
treating,
managing
across
Language: Английский
Antimicrobial stewardship situation analysis in selected hospitals in Zambia: findings and implications from a national survey
Frontiers in Public Health,
Journal Year:
2024,
Volume and Issue:
12
Published: Sept. 27, 2024
Background
Antimicrobial
stewardship
(AMS)
programs
are
critical
in
combating
antimicrobial
resistance
(AMR).
In
Zambia,
there
is
little
information
regarding
the
capacity
of
hospitals
to
establish
and
implement
AMS
programs.
The
objective
this
study
was
conduct
a
baseline
assessment
WHO
core
elements
for
an
program
implementation
eight
Zambia.
Materials
methods
We
conducted
exploratory
cross-sectional
from
September
2023
December
using
self-scoring
Periodic
National
Healthcare
Facility
Assessment
Tool
World
Health
Organization
(WHO)
policy
guidance
on
integrated
activities
human
health.
Eight
public
were
surveyed
across
five
provinces
Data
analyzed
tool
thematic
analysis.
Results
Overall,
62.5%
(6/8)
facilities
scored
low
(below
60%)
implementing
Most
had
challenges
with
reporting
feedback
within
hospital
(average
score
=
46%),
Drugs
Therapeutics
Committee
(DTC)
functionality
49%),
actions
50%),
education
training
54%),
leadership
commitment
56%).
overall
all
average
(56%).
All
(100%)
did
not
have
allocated
budget
Finally,
neither
antibiograms
guide
utilization
nor
AMS-trained
staff
more
than
50%
surveyed.
Conclusion
This
found
these
hospitals,
especially
where
DTCs
non-functional.
identified
gaps
require
urgent
attention
sustainable
multidisciplinary
Language: Английский
The Effect of Educational Intervention on Healthcare Workers’ Awareness and Knowledge of Antimicrobial Resistance, Stewardship, and Surveillance: Opportunities for Antimicrobial and Diagnostic Stewardship
Steward Mudenda,
No information about this author
Victor Daka,
No information about this author
Mapeesho Kamayani
No information about this author
et al.
Pharmacology & Pharmacy,
Journal Year:
2025,
Volume and Issue:
16(05), P. 125 - 149
Published: Jan. 1, 2025
Language: Английский
Antibiotic use at the Centre Hospitalier Universitaire de Zone d'Abomey Calavi/Sô-Ava (CHUZ/AS) in Benin: a point prevalence survey
Morelle Sèssiwèdé Gnimavo,
No information about this author
Bawa Boya,
No information about this author
Steward Mudenda
No information about this author
et al.
JAC-Antimicrobial Resistance,
Journal Year:
2024,
Volume and Issue:
7(1)
Published: Dec. 26, 2024
Abstract
Background
Antimicrobial
stewardship
promotes
the
appropriate
use
of
antibiotics
to
prevent
emergence
and
spread
antimicrobial
resistance.
This
study
evaluated
using
a
point
prevalence
survey
at
Centre
Hospitalier
Universitaire
de
Zone
d'Abomey
Calavi/Sô-Ava
(CHUZ/AS)
in
Benin.
Methods
cross-sectional
utilized
WHO
methodology
for
monitoring
antibiotic
among
inpatients
hospitals.
The
was
conducted
from
11
January
2022
19
hospitalized
patients
before
8:00
a.m.
on
day
survey.
Results
Of
111
inpatient
medical
files
reviewed,
82.9%.
number
received
per
patient
ranged
1
5,
with
mean
2.45
±
1.11
median
2.
most
commonly
prescribed
class
beta-lactams
(46.7%),
aminoglycosides
(20.6%)
nitroimidazoles
(19.7%).
According
AWaRe
classification,
30.4%
Access
group
44%
combination
Watch
antibiotics;
treatment
empiric
94.5%
encounters.
Only
22.7%
were
treated
based
microbiological
examination/culture
sensitivity
testing.
Conclusions
found
high
CHUZ/AS
Tertiary
Care
Hospital
ampicillin,
metronidazole
ceftriaxone.
Consequently,
low
culture
testing
guide
treatment,
particularly
paediatric
surgical
population,
preference
broad-spectrum
suggests
that
is
not
optimal.
Therefore,
programmes,
policies
guidelines
must
be
instigated
strengthened
address
these
gaps
promote
rational
antibiotics.
Language: Английский