Reshaped Gut Microbial Composition and Functions Associated with the Antifatigue Effect of Salidroside in Exercise Mice DOI
Hongkang Zhu,

Fanglin Shen,

Xiaochen Wang

et al.

Molecular Nutrition & Food Research, Journal Year: 2023, Volume and Issue: 67(12)

Published: April 21, 2023

Salidroside (SA) is an active compound derived from Rhodiola rosea and widely used in healthcare foods. However, the underlying mechanism its specific role regulating gut microbial community during exercise (Ex) remains unknown.Mice are subjected to a weight-loaded swimming test (WST) Ex determine how microbiota affects antifatigue activity of SA. The SA-treated group mice (100 mg kg-1 .bw.) display significant increase time compared control (26.2 versus 10.5 min, p < 0.01), as well respiratory enzymatic activities after swimming. significantly higher than RS (regular rest) bacteria profiles + SA change with species diversity abundance. Receiver operating characteristic (ROC) curves Alistipes, Rikenellaceae, Parabacteroides, Candidatus Arthromitus, Lactobacillus indicate high diagnostic utility distinguish treatment. Microbial function analysis shows that may improve Ex-induced fatigue by modulating energy metabolism-related processes.SA demonstrates effects on various levels metabolism composition, providing insights into mechanisms natural prebiotic.

Language: Английский

Understanding the gut microbiota and sarcopenia: a systematic review DOI
Chaoran Liu, Wing‐Hoi Cheung,

Jie Li

et al.

Journal of Cachexia Sarcopenia and Muscle, Journal Year: 2021, Volume and Issue: 12(6), P. 1393 - 1407

Published: Sept. 14, 2021

Language: Английский

Citations

221

Multifactorial Mechanism of Sarcopenia and Sarcopenic Obesity. Role of Physical Exercise, Microbiota and Myokines DOI Creative Commons
Jan Bilski, Piotr Pierzchalski, Marian Szczepanik

et al.

Cells, Journal Year: 2022, Volume and Issue: 11(1), P. 160 - 160

Published: Jan. 4, 2022

Obesity and ageing place a tremendous strain on the global healthcare system. Age-related sarcopenia is characterized by decreased muscular strength, muscle quantity, quality, functional performance. Sarcopenic obesity (SO) condition that combines has substantial influence older adults’ health. Because of complicated pathophysiology, there are disagreements challenges in identifying diagnosing SO. Recently, it become clear dysbiosis may play role onset progression Skeletal secretes myokines during contraction, which an important controlling growth, function, metabolic balance. Myokine dysfunction can cause aggravate obesity, sarcopenia, The only ways to prevent slow particularly sarcopenic physical activity correct nutritional support. While exercise cannot completely age-related loss certainly delay development down rate sarcopenia. purpose this review was discuss potential pathways deterioration obese individuals. We also want present current understanding various factors, including microbiota myokines, process

Language: Английский

Citations

140

Fueling Gut Microbes: A Review of the Interaction between Diet, Exercise, and the Gut Microbiota in Athletes DOI Creative Commons
Riley Hughes, Hannah D. Holscher

Advances in Nutrition, Journal Year: 2021, Volume and Issue: 12(6), P. 2190 - 2215

Published: May 28, 2021

The athlete's goal is to optimize their performance. Towards this end, nutrition has been used improve the health of athletes' brains, bones, muscles, and cardiovascular system. However, recent research suggests that gut its resident microbiota may also play a role in athlete Therefore, athletes should consider dietary strategies context potential effects on microbiota, including impact sports-centric (e.g., protein supplements, carbohydrate loading) as well gut-centric probiotics, prebiotics) This review provides an overview interaction between diet, exercise, focusing both athletic Current evidence could, theory, contribute intake performance by influencing microbial metabolite production, gastrointestinal physiology, immune modulation. Common such high simple intake, low fiber food avoidance adversely and, turn, Conversely, adequate fiber, variety sources, emphasis unsaturated fats, especially omega-3 (ɷ-3) fatty acids, addition consumption prebiotics, synbiotics, have shown promising results optimizing Ultimately, while emerging area research, more studies are needed incorporate, control, manipulate all 3 these elements (i.e., microbiome) provide recommendations for how "fuel microbes."

Language: Английский

Citations

118

Gut microbes and muscle function: can probiotics make our muscles stronger? DOI
Muriel Giron, Muriel Thomas, Dominique Dardevet

et al.

Journal of Cachexia Sarcopenia and Muscle, Journal Year: 2022, Volume and Issue: 13(3), P. 1460 - 1476

Published: March 12, 2022

Language: Английский

Citations

117

Gut Microbiota, Probiotics and Physical Performance in Athletes and Physically Active Individuals DOI Open Access
Maija Marttinen, Reeta Ala-Jaakkola, Arja Laitila

et al.

Nutrients, Journal Year: 2020, Volume and Issue: 12(10), P. 2936 - 2936

Published: Sept. 25, 2020

Among athletes, nutrition plays a key role, supporting training, performance, and post-exercise recovery. Research has primarily focused on the effects of diet in support an athletic physique; however, role played by intestinal microbiota been much neglected. Emerging evidence shown association between composition physical activity, suggesting that modifications gut may contribute to performance host. Probiotics represent potential means for beneficially influencing composition/function but can also impact overall health In this review, we provide overview existing studies have examined reciprocal interactions activity microbiota. We further evaluate clinical supports probiotics recovery, cognitive outcomes among athletes. addition, discuss mechanisms action through which affect exercise outcomes. summary, beneficial microbes, including probiotics, promote athletes enhance capacity. Furthermore, high-quality studies, with adequate power, remain necessary uncover roles are populations modes behind their benefits.

Language: Английский

Citations

119

Probiotics in Fish Nutrition—Long-Standing Household Remedy or Native Nutraceuticals? DOI Open Access
Sven Wuertz,

Arne Schroeder,

Konrad M. Wanka

et al.

Water, Journal Year: 2021, Volume and Issue: 13(10), P. 1348 - 1348

Published: May 13, 2021

Over the last decades, aquaculture production increased rapidly. The future development of industry highly relies on sustainable utilization natural resources. need for improving disease resistance, growth performance, food conversion, and product safety human consumption has stimulated application probiotics in aquaculture. Probiotics increase feed improve health status, raise decrease stress susceptibility, general vigor. Currently, most still originate from terrestrial sources rather than fish. However, host-associated (autochthonous) are likely more persistent gastrointestinal tract fish may, therefore, exhibit longer-lasting effects host. Probiotic candidates commonly screened vitro assays, but transfer to vivo assessment is often problematic. In conclusion, modulation microbiome by use complex promising, a solid understanding interactions involved only its infancy requires further research. could be used explore novel ingredients such as chitin-rich insect meal, which cannot digested host alone. Most importantly, offer opportunity among pressing problems

Language: Английский

Citations

64

A Narrative Review of Gut-Muscle Axis and Sarcopenia: The Potential Role of Gut Microbiota DOI Creative Commons
Jiaxi Zhao,

Yiqin Huang,

Xiaofeng Yu

et al.

International Journal of General Medicine, Journal Year: 2021, Volume and Issue: Volume 14, P. 1263 - 1273

Published: April 1, 2021

Abstract: Sarcopenia is a multifactorial disease related to aging, chronic inflammation, insufficient nutrition, and physical inactivity. Previous studies have suggested that there relationship between sarcopenia gut microbiota,namely, the gut-muscle axis. The present review highlights microbiota can affect muscle mass function from inflammation immunity,substance energy metabolism, endocrine insulin sensitivity, etc., directly or indirectly establishing connection with sarcopenia, thereby realizing “gut-muscle axis”. Keywords: microbiota,

Language: Английский

Citations

61

Mechanisms Linking the Gut-Muscle Axis With Muscle Protein Metabolism and Anabolic Resistance: Implications for Older Adults at Risk of Sarcopenia DOI Creative Commons
Konstantinos Prokopidis, Edward S. Chambers, Mary Ní Lochlainn

et al.

Frontiers in Physiology, Journal Year: 2021, Volume and Issue: 12

Published: Oct. 26, 2021

Aging is associated with a decline in skeletal muscle mass and function—termed sarcopenia—as mediated, part, by anabolic resistance. This metabolic phenomenon describes the impaired response of protein synthesis (MPS) to provision dietary amino acids practice resistance-based exercise. Recent observations highlight gut-muscle axis as physiological target for combatting resistance reducing risk sarcopenia. Experimental studies, primarily conducted animal models aging, suggest mechanistic link between gut microbiota atrophy, mediated via modulation systemic acid availability low-grade inflammation that are both factors known underpin Moreover, vivo vitro studies demonstrate action specific bacteria ( Lactobacillus Bifidobacterium ) increase elicit an anti-inflammatory intestinal lumen. Prospective lifestyle approaches have recently been examined context mitigating sarcopenia risk. These include increasing fiber intake promotes growth development bacteria, thus enhancing production short-chain fatty (SCFA) (acetate, propionate, butyrate). Prebiotic/probiotic/symbiotic supplementation also generates SCFA may mitigate older adults microbiota. Preliminary evidence highlights role exercise SCFA. Accordingly, combine diets rich probiotic training serve produce microbial diversity, adults. Future warranted establish direct distinct phenotypes on utilization postprandial stimulation

Language: Английский

Citations

58

A multistrain probiotic improves handgrip strength and functional capacity in patients with COPD: A randomized controlled trial DOI
Asima Karim, Tahir Muhammad, M. Shahid Iqbal

et al.

Archives of Gerontology and Geriatrics, Journal Year: 2022, Volume and Issue: 102, P. 104721 - 104721

Published: May 10, 2022

Language: Английский

Citations

54

Gut microbiota as a promising therapeutic target for age-related sarcopenia DOI Open Access
Ting Zhang,

Jin-Ke Cheng,

Yaomin Hu

et al.

Ageing Research Reviews, Journal Year: 2022, Volume and Issue: 81, P. 101739 - 101739

Published: Sept. 28, 2022

Language: Английский

Citations

54