Anti-Inflammatory, Antioxidant, and Other Health Effects of Dragon Fruit and Potential Delivery Systems for Its Bioactive Compounds

Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(1), P. 159 - 159

Published: Jan. 3, 2023

Dragon fruit (

Language: Английский

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Anthocyanins from a new hybrid sweet potato peel cultivated in Northern Thailand mitigate LPS-induced inflammation and RANKL-induced osteoporosis by regulating ROS-mediated pathways

Inflammopharmacology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 13, 2025

Maejo 341 Sweet potato (MSP) is a new purple sweet variety cultivated in Northern Thailand, but its health benefits are unknown. This study aimed to investigate antioxidant, anti-inflammatory, and anti-osteoporotic activities, as well anthocyanin content. The peel flesh of MSP were extracted with ethanol water. Compared the extracts, extracts presented greater antioxidant capacity rich phenolics, flavonoids, anthocyanins, namely, cyanidin-3-O-glucoside, peonidin-3-O-glucoside, pelargonidin-3-O-glucoside, cyanidin, peonidin. suppressed lipopolysaccharide-induced inflammation by inhibiting secretion proinflammatory cytokines enzymes, including TNF-α, IL-1β, IL-6, COX-2, iNOS, reducing nitric oxide matrix metalloproteinase-9 secretion. inhibited RANKL-induced NF-κB MAPK pathways downregulated osteoclastogenic marker expression. Under LPS RANKL treatment, notably reduced reactive oxygen species production while increasing gene Furthermore, they increased osteoblast viability slightly raise alkaline phosphatase activity. These findings suggest that could be used functional food alleviate oxidative stress inflammation-related osteoporosis.

Language: Английский

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Maturation Process, Nutritional Profile, Bioactivities and Utilisation in Food Products of Red Pitaya Fruits: A Review

Foods, Journal Year: 2021, Volume and Issue: 10(11), P. 2862 - 2862

Published: Nov. 18, 2021

Red pitaya (Hylocereus polyrhizus, red pulp with pink peel), also known as dragon fruit, is a well-known species of fruit. Pitaya seeds and peels have been reported to exhibit higher concentrations total polyphenols, beta-cyanins amino acid than pulp, while anthocyanins (i.e., cyanidin 3-glucoside, delphinidin 3-glucoside pelargonidin 3-glucoside) were only detected in the extracts. Beta-cyanins, phenolics flavonoids found increase gradually during fruit maturation pigmentation appeared earlier peel. The phytochemicals extracted purified by various techniques broadly used natural, low-cost, beneficial healthy compounds foods, including bakery, wine, dairy, meat confectionery products. These bioactive components regulative influences on human gut microbiota, glycaemic response, lipid accumulation, inflammation, growth microbials mutagenicity, but mechanisms are yet be understood. objective this study was systematically summarise effect pitaya's process nutritional profile techno-functionality variety food findings review provide valuable suggestions for processing industry, leading novel formulations supported molecular research.

Language: Английский

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Trends on valorization of pitaya fruit biomass through value-added and green extraction technology – A critical review of advancements and processes

Trends in Food Science & Technology, Journal Year: 2023, Volume and Issue: 138, P. 339 - 354

Published: June 17, 2023

Language: Английский

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Betacyanins and Anthocyanins in Pulp and Peel of Red Pitaya (Hylocereus polyrhizus cv. Jindu), Inhibition of Oxidative Stress, Lipid Reducing, and Cytotoxic Effects

Frontiers in Nutrition, Journal Year: 2022, Volume and Issue: 9

Published: June 23, 2022

This study aimed to promote red pitaya fruit parts as alternate sources of nutraceuticals. The Chinese origin was determined for its in vitro efficacy, where the extracts were evaluated based on selected antioxidative properties, lipid-reducing capacity, and cytotoxicity. betanin, total betacyanins, anthocyanins, DPPH radical scavenging activity pulp peel by spectrophotometric analyses. Cell culture assays used examine efficacy cytotoxicity extracts. result showed that extract had a higher betacyanins anthocyanins content than extract, but lower effect extract. also protective reducing oxidative stress, especially All samples low anticancer potential except betanin anthocyanin standards. could be attributed anthocyanins. Both weak because these contained polysaccharides other phytochemicals not cytotoxic. As cytotoxic, it is potent source stress.

Language: Английский

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HPLC-ESI/MS-MS metabolic profiling of white pitaya fruit and cytotoxic potential against cervical cancer: Comparative studies, synergistic effects, and molecular mechanistic approaches

Journal of Pharmaceutical and Biomedical Analysis, Journal Year: 2024, Volume and Issue: 244, P. 116121 - 116121

Published: March 19, 2024

Language: Английский

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Valorization of dragon fruit waste to value-added bioproducts and formulations: A review

Critical Reviews in Biotechnology, Journal Year: 2023, Volume and Issue: 44(6), P. 1061 - 1079

Published: Sept. 24, 2023

Owing to the increasing worldwide population explosion, managing waste generated from food sector has become a cross-cutting issue globally, leading environmental, economic, and social issues. Circular economy-inspired valorization approaches have been steadily, generating new business opportunities developing valuable bioproducts using waste, especially fruit wastes, that may several applications in energy-food-pharma sectors. Dragon is one such resource, which rich value-added chemicals oils, can be renewable resource produce compounds of potential different industries. Pretreatment extraction processes biorefineries are important strategies for recovering biomolecules. There methods valorization, including green extractions biological conversion approaches. However, microbe-based advanced technologies valorizing dragon into bioethanol, bioactive products, pharmaceuticals, other valued products by reusing or recycling them. This state-of-the-art review briefly overviews management eco-friendly cost-effective technologies. Furthermore, various components obtained critically discussed concerning industrial Several sectors, as food, biofuels, reviewed detail.

Language: Английский

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Effects of apples ( Malus domestica ) and their derivatives on metabolic conditions related to inflammation and oxidative stress and an overview of by-products use in food processing

Critical Reviews in Food Science and Nutrition, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 32

Published: July 24, 2024

Apple (Malus domestica) is the third most produced fruit worldwide. It a well-known source of bioactive compounds mainly represented by hydroxycinnamic acids, flavan-3-ols, dihydrochalcones, dehydroascorbic acid, carotenoids, chlorogenic epicatechin, and phloridzin. Due to lack recent evaluation clinical trials associated with apple consumption, this review investigated effects on metabolic conditions related inflammation oxidative stress reviewed applications waste food products. Thirty-three studies showed that apples or its derivatives exhibit anti-inflammatory antioxidant actions, improve blood pressure, body fat, insulin resistance, dyslipidemia, reduce cardiovascular risks. Apples have great economic impact due several in industry as supplement since it has impressive nutritional value. Dietary fiber from pomace can be used substitute for fat products an improver content meat also bakery confectionary fermented produce alcohol. Pomace phytocompounds isolated applied antioxidants The potential use by-products environmental damage.

Language: Английский

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Dragon fruit: Exploring bioactive compounds and their promising role in functional food innovation and value-added products

Journal of Food Composition and Analysis, Journal Year: 2025, Volume and Issue: unknown, P. 107370 - 107370

Published: Feb. 1, 2025

Language: Английский

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Evaluation of antioxidant activity, phenolic compound profile and accelerated storage of chestnut based mixed pulp powders

Journal of Food Measurement & Characterization, Journal Year: 2025, Volume and Issue: unknown

Published: April 2, 2025

Language: Английский

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