Current Issues in Molecular Biology,
Journal Year:
2025,
Volume and Issue:
47(3), P. 174 - 174
Published: March 6, 2025
Parkinson's
disease
(PD)
is
the
second
most
common
neurodegenerative
disease,
and
its
prevalence
expected
to
double
in
next
30
years.
Currently,
no
effective
treatment
exists
for
disease.
Thus,
research
has
focused
on
discovering
new
natural
compounds
with
strong
neuroprotective
potential.
This
study
aimed
investigate
effects
of
methanol
extract
Desmodesmus
arthrodesmiformis
EM13
(DaMe)
mitochondrial
damage
pathway
an
vitro
model
PD.
The
isolate
was
first
grown
under
appropriate
culture
conditions,
then
prepared
use
experiments.
total
lipid
protein
contents,
fatty
acid
composition,
elemental
content
DaMe
were
subsequently
determined.
Human
SH-SY5Y
neuroblastoma
cells
pretreated
nontoxic
concentrations
before
6-hydroxydopamine
(6-OHDA)
toxicity.
Pretreatment
at
100,
250,
500
µg/mL
showed
a
effect
6-OHDA-induced
by
decreasing
reactive
oxygen
species
(ROS)
production,
oxidant
status
(TOS),
increasing
antioxidant
capacity
(TAC),
membrane
potential
(ΔΨm),
oxidative
DNA
damage,
regulating
gene
expressions
related
PD
apoptosis.
Given
results
our
study,
we
suggest
that
can
be
used
as
source
producing
drugs
dietary
supplements
intended
treat
International Journal of Molecular Sciences,
Journal Year:
2023,
Volume and Issue:
24(20), P. 15199 - 15199
Published: Oct. 15, 2023
Aging
is
generally
defined
as
a
time-dependent
functional
decline
that
affects
most
living
organisms.
The
positive
increase
in
life
expectancy
has
brought
along
aging-related
diseases.
Oxidative
stress
caused
by
the
imbalance
between
pro-oxidants
and
antioxidants
can
be
given
one
of
causes
aging.
At
same
time,
oxidative
reactive
oxygen
species
(ROS)
main
reason
for
diseases
such
cardiovascular,
neurodegenerative,
liver,
skin,
eye
diabetes.
Carotenoids,
natural
compound,
used
to
change
course
aging
diseases,
thanks
their
highly
effective
oxygen-quenching
ROS-scavenging
properties.
Therefore,
this
narrative
review,
conducted
using
PubMed,
ScienceDirect,
Google
Scholar
databases
complying
with
Scale
Assessment
Narrative
Review
Articles
(SANRA)
guidelines,
effects
carotenoids
on
were
analyzed.
Carotenoids
are
fat-soluble,
unsaturated
pigments
occur
naturally
plants,
fungi,
algae,
photosynthetic
bacteria.
A
large
number
works
have
been
relation
Animal
human
studies
found
significantly
reduce
obesity
fatty
lower
blood
sugar,
improve
liver
fibrosis
cirrhosis,
well
risk
cardiovascular
disease
erythema
formation,
while
also
lowering
glycated
hemoglobin
fasting
plasma
glucose
levels.
Carotenoid
supplementation
may
preventing
delaying
treating
fatigue
dry
disease,
improving
macular
function.
These
stop,
delay,
or
treat
due
powerful
antioxidant,
restorative,
anti-proliferative,
anti-inflammatory,
anti-aging
As
an
increasingly
population
emerges
globally,
review
could
provide
important
prospective
contribution
public
health.
Applied Sciences,
Journal Year:
2024,
Volume and Issue:
14(6), P. 2483 - 2483
Published: March 15, 2024
At
present,
the
incorporation
of
microalgae
into
bread
and
related
cereal
products
has
attracted
attention
due
to
their
potential
for
enhancing
nutritional
profiles
impact
on
health.
In
this
study,
4%
Chlorella
vulgaris,
Phaeodactylum
tricornutum,
Tetraselmis
chuii
were
added
wheat
flour
produce
assesses
dough
rheology
behaviour,
quality
performance,
nutritive
value,
bioactive
profile
bread.
The
results
showed
that
T.
strengthened
network,
whereas
P.
tricornutum
exerted
minimal
influence.
Notably,
C.
vulgaris
induced
a
pronounced
weakening
protein
network
within
matrix,
leading
disruptions
in
structure
subsequent
alterations
starch
gelatinisation
retrogradation.
These
changes
lead
reduction
volume
(22.7%)
corresponding
increase
its
firmness
when
was
added.
contrast,
had
no
significant
effect
volume.
All
species
caused
dark
green
colour
enhanced
composition,
namely
terms
content
(14.7%
bread)
mineral
profile.
breads
containing
exhibited
noticeable
both
total
phenolic
(from
7.22
control
38.52
(µg
GAE/g))
antioxidant
capacity
117.29
591.96
TEAC/g)
measured
by
FRAP).
Antioxidants,
Journal Year:
2024,
Volume and Issue:
13(3), P. 276 - 276
Published: Feb. 24, 2024
UVA
radiation
leads
to
oxidative
stress
and
inflammation
in
skin
cells.
Therefore,
the
aim
of
this
study
was
compare
effect
lipid
extracts
from
microalgae
Nannochloropsis
oceanica
(N.o.)
(marine)
Chlorococcum
amblystomatis
(C.a.)
(freshwater)
on
redox
balance
PUFA
metabolism
human
fibroblasts
modified
by
UVA.
Lipid
both
types
introduced
into
fibroblast
medium
after
irradiation
significantly
reduced
level
ROS
enhanced
expression
Nrf2,
which
increased
activity/level
antioxidants
(SOD1/2,
CAT,
GSH,
Trx).
The
reduction
accompanied
a
decrease
4-HNE,
its
protein
adducts
carbonyl
groups.
Microalgae
also
activity
COX1/2,
FAAH
MAGL
UVA,
as
consequence,
mediators
(especially
N.o.)
decreased,
group
endocannabinoids
(AEA,
2-AG,
PEA)
eicosanoids
(PGE2,
15d-PGJ2,
TXB2,
15-HETE),
acting
mainly
through
receptors
related
G
protein,
increases
This
further
contributed
pro-inflammatory
signaling
at
NF-κB
TNFα
levels.
it
is
suggested
that
N.o.
C.a.
can
be
used
regenerate
disturbed
radiation.
Mansoura Veterinary Medical Journal,
Journal Year:
2024,
Volume and Issue:
25(1)
Published: Jan. 1, 2024
Background
Selenium
nanoparticles
(SeNPs)
were
synthesized
using
a
green
method
with
Pediastrum
boryanum
extract
as
the
reducing
and
capping
agent.
Objectives
The
algal
SeNPs
characterized
for
their
morphological
characters
biological
efficacy.
Methods
Characterization
was
conducted
UV-vis
spectroscopy,
Fourier
transform
infrared
spectroscopy
(FTIR),
transmission
electron
microscopy
(TEM),
zeta
potential
analysis.
Results
TEM
revealed
spherical
tetragonal
sizes
ranging
from
72.16-89.45
nm.
FTIR
confirmed
presence
of
functional
groups
on
surfaces,
indicating
role
agents.
Phytochemical
analysis
showed
that
had
higher
total
phenolics
(51.114
mg
GAE/g)
flavonoids
(19.225
QE/g)
than
(27.154
9.931
mg/g,
respectively).
also
exhibited
greater
antioxidant
activity
in
1,1-Diphenyl-2-picrylhydrazyl
(DPPH)
radical
scavenging
assay.
Evaluation
antimicrobial
effects
against
fish
pathogens
demonstrated
broad-spectrum
inhibitory
Aeromonas
veronii,
A.
sobria,
Streptococcus
iniae,
Edwardsiella
ictaluri,
hydrophila
(MIC
64-256
μg/mL).
A
brine
shrimp
lethality
assay
(BSLA)
potent
dose-dependent
cytotoxicity
both
(LC50
51.56
μg/mL)
11.88
Overall,
this
synthesis
successfully
produced
stable
enhanced
bioactivities.
Conclusions
These
results
highlight
microalga
P.
sustainable
nano-factory
significant
bioactive
warrant
further
pharmacological
investigation.
Plants,
Journal Year:
2023,
Volume and Issue:
12(9), P. 1896 - 1896
Published: May 6, 2023
Improvements
in
agricultural
productivity
are
required
to
meet
the
demand
of
a
growing
world
population.
Phytopathogens,
weeds,
and
insects
challenges
production.
The
toxicity
widespread
application
persistent
synthetic
pesticides
poses
major
threat
human
ecosystem
health.
Therefore,
sustainable
strategies
control
pests
essential
for
systems
enhance
within
green
paradigm.
Allelochemicals
less
persistent,
safer,
friendly
alternative
efficient
pest
management,
as
they
tend
be
toxic
non-target
organisms
more
easily
degradable.
Microalgae
produce
great
variety
allelopathic
substances
whose
biocontrol
potential
against
insects,
phytopathogenic
fungi
bacteria
has
received
much
attention.
This
review
provides
up-to-date
information
critical
perspective
on
allelochemicals
from
microalgae
their
biopesticides.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(18), P. 3223 - 3223
Published: Sept. 23, 2024
Undernutrition
is
an
important
global
health
problem,
especially
in
children
and
older
adults.
Both
reversal
of
maternal
child
undernutrition
heathy
ageing
have
become
United
Nations-supported
initiatives,
leading
to
increased
attention
nutritional
interventions
targeting
undernutrition.
One
feasible
option
microalgae,
the
precursor
all
terrestrial
plants.
Most
commercially
farmed
microalgae
are
photosynthetic
single-celled
organisms
producing
organic
carbon
compounds
oxygen.
This
review
will
discuss
commercial
opportunities
grow
microalgae.
Microalgae
produce
lipids
(including
omega-3
fatty
acids),
proteins,
carbohydrates,
pigments
micronutrients
so
can
provide
a
suitable
underutilised
alternative
for
addressing
The
benefits
nutrients
derived
from
been
identified,
thus
they
candidates
issues
globally.
potential
microalgae-derived
be
converted
into
food
products.
advantages
cultivation
include
that
it
does
not
need
arable
land
or
pesticides.
Additionally,
most
species
still
unexplored,
presenting
options
further
development.
Further,
usefulness
other
purposes
such
as
bioremediation
biofuels
increase
knowledge
these
microorganisms,
allowing
development
more
efficient
production
interventions.
BioTech,
Journal Year:
2023,
Volume and Issue:
12(3), P. 53 - 53
Published: Aug. 3, 2023
Incorporating
a
variety
of
microalgae
into
wastewater
treatment
is
considered
an
economically
viable
and
environmentally
sound
strategy.
The
present
work
assessed
the
growth
characteristics
Chlorella
sorokiniana
during
cultivation
in
balanced
synthetic
media
domestic
wastewater.
Increasing
NH4+-N
concentration
to
360
mg
L-1
adding
extra
PO43--P
SO42--S
(up
80
36
L-1,
respectively)
contributed
increase
total
biomass
levels
(5.7-5.9
g
L-1)
C.
media.
Under
these
conditions,
maximum
concentrations
chlorophylls
carotenoids
were
180
±
7.5
26
1.4
respectively.
Furthermore,
when
studying
three
types
wastewaters,
it
was
noted
that
only
one
productive
sorokiniana,
but
all
wastewaters
stimulated
increased
accumulation
protein.
Finally,
alga,
growing
optimal
unsterilized
wastewater,
showed
specific
rate
0.73
day-1,
productivity
0.21
100%
removal.
These
results
demonstrate
tested
alga
actively
adapts
changes
composition
medium
accumulates
high
protein
systems
with
poor-quality
water.
