Spotlight on therapeutic efficiency of green synthesis metals and their oxide nanoparticles in periodontitis

Journal of Nanobiotechnology, Journal Year: 2024, Volume and Issue: 22(1)

Published: Jan. 5, 2024

Abstract Periodontitis, one of the most prevalent dental diseases, causes loss bone and gum tissue that hold teeth in place. Several bacteria, commonly present clinically healthy oral cavities, may induce perpetuate periodontitis when their concentration rises gingival sulcus. Antibacterial effect against various Gram-negative Gram-positive including pathogenic drug-resistant ones, has been shown for several distinct transient metal oxide NPs. Therefore, NPs be used biomedicine to treat periodontal problems nanotechnology inhibit development microorganisms. Instead using harmful chemicals or energy-intensive machinery, biosynthesis nanoparticles (NPs) suggested. To produce NPs, ideal technique is “Green” synthesis because its low toxicity safety human health environment. Gold (AuNPs) appear less toxic mammalian cells than other nanometals antibacterial activity not dependent on reactive oxygen species (ROS). AgNPs also possess chemical stability, catalytic activity, superior electrical thermal conductivity, name a few advantageous characteristics. It was observed zinc (ZnO) copper (Cu) exhibited discernible inhibitory effects gram-positive gram-negative bacterial strains, respectively. ZnO demonstrated bactericidal microorganisms responsible periodontitis. Medications containing magnetic are highly effective multidrug-resistant fungal infections. The titanium dioxide (TiO 2 ) implicated elevating salivary peroxidase individuals diagnosed with chronic Furthermore, specific metallic have potential enhance antimicrobial efficacy treatments combined. these as well only some metals oxides synthesized environmentally friendly ways therapeutic benefits Graphical

Language: Английский

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Green synthesis of CuFe2O4 nanoparticles from bioresource extracts and their applications in different areas: a review

Biomass Conversion and Biorefinery, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 6, 2024

Language: Английский

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Biogenic metallic nanoparticles: biomedical, analytical, food preservation, and applications in other consumable products

Frontiers in Nanotechnology, Journal Year: 2023, Volume and Issue: 5

Published: May 2, 2023

Biogenic metallic nanoparticles (BMNPs) are nanostructure materials synthesized through biological processes that have gained significant attention due to their small size and high surface area-to-volume ratio. BMNPs several advantages over chemically ones eco-friendly synthesis regimen, sustainability, biocompatibility, diverse multifarious biomedical applications. Moreover, the superior cytocompatibility stability capping layer (MNPs), reduces like hood of toxicity side effects, making them a safer alternative traditional drug delivery methods. Among promising applications BMNPs, antibacterial activity, analytical sensing heavy metals, roles in food preservations been widely explored. In addition, imaging, also investigated for therapeutic activity such as antimicrobial efficacy against skin soft tissue nosocomial pathogens targeting cancer cells therapy. The present review bestows characterization techniques involved with MNPs compressive aspects biogenic using agricultural materials, which cost minimizes use hazardous chemicals. focuses on multifold including biomedical, analytical, preservation food, other consumable goods toxicological aspects.

Language: Английский

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Recent Trends in Biologically Synthesized Metal Nanoparticles and their Biomedical Applications: a Review

Biological Trace Element Research, Journal Year: 2023, Volume and Issue: 202(7), P. 3383 - 3399

Published: Oct. 25, 2023

Language: Английский

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Nanoformulations in Pharmaceutical and Biomedical Applications: Green Perspectives

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(11), P. 5842 - 5842

Published: May 27, 2024

This study provides a brief discussion of the major nanopharmaceuticals formulations as well impact nanotechnology on future pharmaceuticals. Effective and eco-friendly strategies biofabrication are also highlighted. Modern approaches to designing pharmaceutical nanoformulations (e.g., 3D printing, Phyto-Nanotechnology, Biomimetics/Bioinspiration, etc.) outlined. paper discusses need use natural resources for “green” design new with therapeutic efficiency. Nanopharmaceuticals research is still in its early stages, preparation nanomaterials must be carefully considered. Therefore, safety long-term effects not overlooked. The testing represents an essential point their further applications. Vegetal scaffolds obtained by decellularizing plant leaves represent valuable, bioinspired model nanopharmaceutical that avoids using animals. Nanoformulations critical various fields, especially pharmacy, medicine, agriculture, material science, due unique properties advantages over conventional allows improved solubility, bioavailability, targeted drug delivery, controlled release, reduced toxicity. have transitioned from experimental stages being vital component clinical practice, significantly improving outcomes medical fields cancer treatment, infectious diseases, neurological disorders, personalized advanced diagnostics. Here key points highlighting importance. significant challenges, opportunities, directions mentioned final section.

Language: Английский

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Green Fabrication of ZnO Nanoparticles and ZnO/rGO Nanocomposites from Algerian Date Syrup Extract: Synthesis, Characterization, and Augmented Photocatalytic Efficiency in Methylene Blue Degradation

Catalysts, Journal Year: 2024, Volume and Issue: 14(1), P. 62 - 62

Published: Jan. 13, 2024

This innovative article provides a detailed description of the successful biosynthesis zinc nanoparticles (ZnO-NPs) using an aqueous extract Algerian Date Syrup, also known as molasses. A meticulous process was carried out to determine optimal calcination temperature for ZnO-NPs, crucial step in preparation these nanoparticles. The study further extended by creating ZnO/rGOx nanocomposites through hydrothermal method, varying concentrations reduced graphene oxide (rGO) at 5%, 10%, and 15%. characteristics were thoroughly explored, encompassing chemical, optical, morphological aspects, sophisticated analysis techniques such scanning electron microscopy (SEM), UV-visible diffuse reflectance spectroscopy (UV DRS), Fourier-transform infrared (FTIR), X-ray diffraction (XRD). These analyses provided in-depth understanding structure properties nanocomposites. centerpiece this is evaluation photocatalytic degradation capacity ZnO-NPs materials have demonstrated their ability act cost-effective environmentally friendly photocatalysts wastewater treatment. Experiments on methylene blue under UV irradiation conducted, yielding impressive results: efficiency 86.6% achieved 140 min 1 g/L rate reached 100% with ZnO/rGO catalyst same time frame, highlighting its superiority photocatalyst. Furthermore, examined variables affecting photocatalysis experiment, including solution’s pH amount catalyst. results revealed that photocatalyst neutral conditions concentration g/L, providing information practical use materials. enriched highlights promising potential efficient degradation, paving way significant environmental applications

Language: Английский

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Green synthesis of ZnO nanoparticles using Justicia adhatoda for photocatalytic degradation of malachite green and reduction of 4-nitrophenol

RSC Advances, Journal Year: 2025, Volume and Issue: 15(4), P. 2958 - 2980

Published: Jan. 1, 2025

Achieving the smallest crystallite/particle size of zinc oxide nanoparticles (ZnO NPs) reported to date, measuring 5.2/12.41 nm with Justicia adhatoda (J. adhatoda) leaf extract, this study introduces a facile green synthesis. Utilizing aqueous J. extract as both reducing and stabilizing agent, method leverages plant's rich phytochemical composition produce highly crystalline morphologically controlled ZnO NPs. This precise particle control highlights effectiveness synthesis process in morphological tuning. The synthesized NPs were thoroughly characterized using XRD, UV-vis spectroscopy, FTIR, FESEM, HRTEM, which collectively revealed superior crystallinity, morphology, unique surface properties conferred by bio-capping. photocatalytic performance these biogenic was evaluated for degradation two model pollutants: malachite (MG), synthetic dye, 4-nitrophenol (4-NP), toxic organic compound. exhibited exceptional efficiency, achieving 99.8% MG within 180 minutes demonstrating rapid reduction 4-NP 4-aminophenol reaction rate constant 0.245 min-1 under UV sunlight irradiation. Mechanistic studies attributed high reactive oxygen species (ROS) generation electron-hole pair interactions, supported improved charge separation area. work not only establishes potential adhatoda-mediated addressing persistent pollutants but also sets benchmark size-controlled By delivering scalable eco-friendly water remediation technologies, advances nanotechnology.

Language: Английский

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Phytochemical Substances—Mediated Synthesis of Zinc Oxide Nanoparticles (ZnO NPS)

Inorganics, Journal Year: 2023, Volume and Issue: 11(8), P. 328 - 328

Published: Aug. 5, 2023

Artemisia absinthium (A. absinthium) leaf extract was successfully used to create zinc oxide nanoparticles (ZnO NPs), and their properties were investigated via several techniques, including X-ray diffraction (XRD), scanning electron microscopy (SEM), energy-dispersive (EDX), Fourier transform infrared (FTIR), ultraviolet–visible spectroscopy (UV–Vis spectroscopy). SEM analysis confirmed the spherical elliptical shapes of particles. Three different peaks observed EDX at energies 1, 8.7, 9.8 keV, together with a single oxygen peak 0.5 keV. The XRD identified ZnO NPs as having hexagonal wurtzite structure, particle size that decreased from 24.39 18.77 nm, an increasing surface area (BET) 4.003 6.032 m2/g for (without extract) green NPs, respectively. FTIR groups molecules accountable stabilization minimization which apparent 3400 cm. Using UV–Vis spectroscopy, band-gap (Egs) estimated, values 2.65 2.79 eV,

Language: Английский

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Greener fabrication of metal nanoparticles using plant materials: A review

Chemical Physics Impact, Journal Year: 2023, Volume and Issue: 7, P. 100255 - 100255

Published: June 25, 2023

The production of assorted metal nanoparticles based on greener synthesis approaches has garnered immense attention, which influences most humans and the environment. Metal are becoming increasingly useful in many areas our everyday lives including medical sciences. In this context, deployment advantageous methodology open new avenues for researchers to generate adhering green chemistry principles exploiting locally available abundant resources rather than toxic chemicals. Various plant materials can be utilized synthesize as they easy access, inexpensive, safe, good environment, readily deployed biosynthesis diverse sizes well shapes, incorporate unique properties constituents their assembly. This review article provides a comprehensive discussion different using renewable sustainable eco-friendly entities. Finally, future outlook fabrication by means method been discussed.

Language: Английский

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Biosynthesis of Silver Nanoparticles Functionalized with Histidine and Phenylalanine Amino Acids for Potential Antioxidant and Antibacterial Activities

ACS Omega, Journal Year: 2023, Volume and Issue: 8(27), P. 24371 - 24386

Published: June 26, 2023

Due to biochemically active secondary metabolites that assist in the reduction, stabilization, and capping of nanoparticles, plant-mediated nanoparticle synthesis is becoming more popular. This because it allows for ecologically friendly, feasible, sustainable, cost-effective green techniques. study describes biosynthesis silver nanoparticles (AgNPs) functionalized with histidine phenylalanine using Lippia abyssinica (locally called koseret) plant leaf extract. The functionalization amino acids was meant enhance biological activities AgNPs. synthesized were characterized UV-Visible absorption (UV-Vis), powder X-ray diffraction (pXRD), scanning electron microscopy (SEM), energy-dispersive (EDX) spectroscopy, transmission (TEM), Fourier transform infrared (FTIR) spectroscopy. surface plasmonic resonance (SPR) peak at about 433 nm confirmed FTIR spectra also revealed phytochemicals extract responsible biogenically On other hand, TEM micrograph morphology AgNP-His had diameters ranging from 5 14 nm. antibacterial against Gram-positive Gram-negative bacteria showed a growth inhibition 8.67 ± 1.25 11.00 0.82 mm Escherichia coli Staphylococcus aureus, respectively, concentration 62.5 μg/mL AgNP-His. Moreover, has an antioxidant activity potential 63.76 1.25% 250 μg/mL. results green-synthesized AgNPs possess promising applications.

Language: Английский

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