Small,
Journal Year:
2023,
Volume and Issue:
19(48)
Published: July 30, 2023
Although
protein
imprinted
materials
with
multiple
templates
are
developed
to
selectively
separate
different
proteins,
it
is
difficult
achieve
the
programmed
adsorption
and
separation
of
proteins
using
one
material,
because
available
constructed
through
irreversible
crosslinking
their
structures
unprogrammable
non-reconstructive.
Herein,
a
novel
nanosphere
(MS@PTL-g-PNIPAM)
designed,
which
not
only
temperature
pH
responsive
but
also
can
dynamically
reversibly
crosslink/de-crosslink
under
ultraviolet
light
wavelengths.
With
help
reversible
photo-crosslinking,
nanospheres
be
repeatedly
into
toward
target
proteins.
Moreover,
prepared
easily
controlled
rebinding
release
benefiting
from
introduced
temperature-
pH-responsive
moieties.
As
consequence,
this
study
realizes
specific
mixture
real
bovine
blood
sequentially
by
programming
material.
It
resource
saving,
time
recyclable,
will
provide
convenience
for
use
in
purification,
drug
delivery,
virus
detection.
Biomaterials Research,
Journal Year:
2023,
Volume and Issue:
27(1)
Published: Feb. 9, 2023
Cancer
is
a
disease
caused
by
abnormal
cell
growth
that
spreads
through
other
parts
of
the
body
and
threatens
life
destroying
healthy
tissues.
Therefore,
numerous
techniques
have
been
employed
not
only
to
diagnose
monitor
progress
cancer
in
precise
manner
but
also
develop
appropriate
therapeutic
agents
with
enhanced
efficacy
safety
profiles.
In
this
regard,
molecularly
imprinted
polymers
(MIPs),
synthetic
receptors
recognize
targeted
molecules
high
affinity
selectivity,
intensively
investigated
as
one
most
attractive
biomaterials
for
theragnostic
approaches.
This
review
describes
diverse
synthesis
strategies
provide
rationale
behind
these
antibodies
provides
selective
overview
recent
vitro
vivo
targeting
biomarkers
diagnosis
applications.
Taken
together,
topics
discussed
concise
guidelines
development
novel
MIP-based
systems
more
precisely
promote
successful
treatment.
Molecularly
The
aim
Processes,
Journal Year:
2024,
Volume and Issue:
12(1), P. 177 - 177
Published: Jan. 12, 2024
In
the
realm
of
sensing
technologies,
appeal
sensors
lies
in
their
exceptional
detection
ability,
high
selectivity,
sensitivity,
cost-effectiveness,
and
minimal
sample
usage.
Notably,
molecularly
imprinted
polymer
(MIP)-based
have
emerged
as
focal
points
interest
spanning
from
clinical
to
environmental
applications.
These
offer
a
promising
avenue
for
rapid,
selective,
reusable,
real-time
screening
diverse
molecules.
The
preparation
technologies
employed
crafting
various
formats,
ranging
microparticles
nanomaterials,
wield
profound
influence.
techniques
significantly
impact
assembly
simplified
systems,
showcasing
remarkable
compatibility
with
other
technologies.
Moreover,
they
are
poised
play
pivotal
role
realization
next-generation
platforms,
streamlining
fabrication
systems
tailored
objectives.
This
review
serves
comprehensive
exploration,
offering
concise
insights
into
sensors,
molecular
imprinting
method,
burgeoning
domain
MIP-based
along
Delving
recent
progress,
this
provides
detailed
summary
advances
imprinted-particle-
gel-based
illuminating
creation
novel
systems.
Additionally,
thorough
examination
distinctive
properties
types
across
different
applications
enriches
understanding
versatility.
concluding
sections,
highlights
most
experiments
cutting-edge
studies
on
targeting
By
encapsulating
current
state
research,
acts
valuable
resource,
snapshot
dynamic
landscape
sensor
development
its
potential
scientific
technological
domains.
Polymers for Advanced Technologies,
Journal Year:
2024,
Volume and Issue:
35(2)
Published: Feb. 1, 2024
Abstract
Molecularly
imprinted
polymer
(MIP)
has
gained
wide
interest
among
researchers
due
to
its
unique
molecular
recognition
of
the
template
that
is
suitable
as
a
drug
carrier.
Therefore,
preparation
and
formulation
MIP
are
significant
suit
needs
intended
use.
Due
significance
in
delivery,
this
review
aims
highlight
various
methods
MIP,
composition
for
both
controlled
stimuli‐responsive
delivery
systems,
release
mechanism
drugs.
In
should
have
sustained
performance
well
flexibility
surface
modification
targeted
via
range
stimuli‐responses,
including
external
stimuli
(magnetic,
light)
internal
(pH,
temperature,
redox,
biological).
The
properties
can
improve
drug's
therapeutic
efficacy
breakthrough
tumor
targeting
application.
Sensors,
Journal Year:
2023,
Volume and Issue:
23(12), P. 5625 - 5625
Published: June 15, 2023
Molecularly
imprinted
polymers
(MIPs)
are
synthetic
with
specific
binding
sites
that
present
high
affinity
and
spatial
chemical
complementarities
to
a
targeted
analyte.
They
mimic
the
molecular
recognition
seen
naturally
in
antibody/antigen
complementarity.
Because
of
their
specificity,
MIPs
can
be
included
sensors
as
element
coupled
transducer
part
converts
interaction
MIP/analyte
into
quantifiable
signal.
Such
have
important
applications
biomedical
field
diagnosis
drug
discovery,
necessary
complement
tissue
engineering
for
analyzing
functionalities
engineered
tissues.
Therefore,
this
review,
we
provide
an
overview
MIP
been
used
detection
skeletal-
cardiac-muscle-related
analytes.
We
organized
review
by
analytes
alphabetical
order.
Thus,
after
introduction
fabrication
MIPs,
highlight
different
types
emphasis
on
recent
works
show
great
diversity,
fabrication,
linear
range
given
analyte,
limit
(LOD),
reproducibility.
conclude
future
developments
perspectives.
