Nutritional Analysis on Wild Edible Fruits of Kolli Hills (Eastern Ghats of Tamil Nadu), India

Published: Jan. 1, 2025

Language: Английский

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Himalayan yellow raspberry (Rubus ellipticus Sm.) potentially important medicinal plant for bioprospection

Vegetos, Journal Year: 2025, Volume and Issue: unknown

Published: March 11, 2025

Language: Английский

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Dietary plants for oral cancer prevention and therapy: A review of preclinical and clinical studies

Phytotherapy Research, Journal Year: 2024, Volume and Issue: 38(11), P. 5225 - 5263

Published: Aug. 28, 2024

Abstract Oral cancer is a disease with high mortality and rising incidence worldwide. Although fragmentary literature on the anti‐oral effects of plant products has been published, comprehensive analysis lacking. In this work, critical evaluation oral preventative or therapeutic dietary plants was conducted. An exhaustive available data supports that numerous exert anticancer effects, including suppression cell proliferation, viability, autophagy, angiogenesis, invasion, metastasis while promoting cycle arrest apoptosis. Plant extracts target several cellular mechanisms, such as reversal epithelial‐to‐mesenchymal transition promotion oxidative stress mitochondrial membrane dysfunction by modulation various signaling pathways. These agents were also found to regulate growth pathways action extracellular signal‐regulated kinase mitogen‐activated protein kinase, inflammation via cyclooxygenase (COX)‐1, COX‐2, nuclear factor‐κB p65, through influence cadherins matrix metalloproteinases. vivo studies support these findings demonstrate decrease in tumor burden, incidence, hyperplastic dysplastic changes. Clinical showed decreased risk. However, high‐quality should be conducted establish clinical efficacy plants. Overall, our study use plants, especially garlic, green tea, longan, peppermint, purple carrot, saffron, tomato, turmeric, for prevention intervention. further research required before application strategy.

Language: Английский

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A recoverable hydrophilic deep eutectic solvent for efficient extraction of polyphenolic compounds from raspberry root

Journal of Food Science, Journal Year: 2024, Volume and Issue: 89(9), P. 5605 - 5617

Published: Aug. 21, 2024

Abstract Green deep eutectic solvents (DESs) are widely used to extract bioactive components from plant biomass; however, hydrophilic DES and component isolation methods have not been developed. In this study, we synthesized (CL‐CA‐DES) using citric acid choline chloride. We combined with environmentally friendly anion‐ cation‐exchange resin column chromatographic methods. This approach extracted isolated four polyphenolic compounds (catechins, epicatechins, procyanidin B1, B2) raspberry root efficiently recovered the DES. CL‐CA‐DES significantly higher contents of catechin B2 compared other solvents. It also substantially epicatechin butyl alcohol, 70% ethanol, water, but there was no significant difference when acetone ethyl acetate. Additionally, B1 acetate, ethanol acetone. The efficiency in by chromatography than that organic solvent extraction precipitation generation methods, method effective recovering a recovery rate 60%. conclusion, study developed new for efficient CL‐CA‐DES, which can be isolating root.

Language: Английский

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Exploration of Anti-Diabetic Potential of Rubus ellipticus smith through Molecular Docking, Molecular Dynamics Simulation, and MMPBSA Calculation

Journal of Nepal Physical Society, Journal Year: 2023, Volume and Issue: 9(2), P. 95 - 105

Published: Dec. 31, 2023

Diabetes is a chronic metabolic disorder affecting majority of the population worldwide. Hyperglycemia leading to diabetes mellitus could be managed through inhibition human pancreatic α-amylase enzyme. Phytochemicals are frequently reported possess anti-diabetic activity normal functioning α-amylase. This study aims find potential inhibitors from Rubus ellipticus Smith with molecular-level understanding using different computational tools. From molecular docking calculations, rubuside F and D possessed good binding affinity -10.0 kcal/mol -9.9 kcal/mol, respectively better than reference drugs (acarbose, miglitol, voglibose metformin). Both compounds showed geometrical stability dynamics simulation accessed in terms RMSD, hydrogen bond count, SASA, Rg RMSF. Binding free energy changes -27.92±4.15 -28.75±4.15 for two ligands indicated sustained thermodynamic spontaneity present adducts. The phytochemicals proposed as treatment diabetes. Further, vitro vivo experiments recommended verification insights course drug design discovery process.

Language: Английский

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A review of botany, traditional applications, phytochemistry, pharmacological applications, and toxicology of Rubus ellipticus Smith fruits

Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2024, Volume and Issue: 397(7), P. 4483 - 4497

Published: Jan. 22, 2024

Language: Английский

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An Ethnobotanical Survey of Plants Used by Communities around Jaunsar-Bawar Region of Uttarakhand, India

Asian Journal of Environment & Ecology, Journal Year: 2024, Volume and Issue: 23(7), P. 95 - 109

Published: May 28, 2024

The Jaunsar Bawar region of Uttarakhand, India, is well-known for its rich biodiversity and cultural history, which inseparably, connected through traditional ecological knowledge (TEK) ethnobotanical traditions. This work explores the practices amongst indigenous communities residing in JaunsarBawar region, 11 villages three tehsils: Kalsi, Tyuni, Chakrata Uttarakhand state India. With extensive field studies, literature reviews, surveys using standard questionnaires, semi-structured interviews with local inhabitants including Vaidyas, Hakeem, forest government officials, study tends to document comprehend relationship between humans plants. It documents usage 65 plant species different growth habits forms medicine, timber, food, fodder, culinary, rituals, other purposes. Insights aid documentation wisdom use across generations tribal region.

Language: Английский

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Anti-diabetic potential of Rubus species: linking conventional knowledge with scientific developments: a review

Food Production Processing and Nutrition, Journal Year: 2024, Volume and Issue: 6(1)

Published: Oct. 8, 2024

Abstract The incidence of diabetes mellitus, a pressing global health concern that is rapidly increasing, has prompted the exploration medicinal plants for potential remedies, particularly those within Rubus genus. This comprehensive review aims to connect traditional knowledge with scientific insights, shedding light on antidiabetic properties various species. An exhaustive literature revealed chingii Hu, idaeus, ulmifolius, fruticosus, amabilis , and some other species exhibited noteworthy effects, each operating via distinct mechanisms. Furthermore, serve as abundant reservoirs bioactive compounds, including flavonoids, phenolic acids, tannins, alkaloids, glycosides, antioxidants, triterpenoids, sterols. As indicated by in vivo vitro studies, these compounds notably improve insulin secretion, increase hepatic glycogen synthesis, inhibit key digestive enzymes, enhance functions β-cells pancreas, effectively reduce blood glucose levels. review, which describes terms both pharmacological effects uses, offers valuable insights future initiatives development innovative therapies. Graphical

Language: Английский

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Floristic diversity and medicinally important plant species in the hillside of Landour, Mussoorie

International Journal of Herbal Medicine, Journal Year: 2024, Volume and Issue: 12(3), P. 01 - 11

Published: Jan. 1, 2024

Himalayan region is well recognized for a plethora of medicinal plants. Landour located at an altitude about 6,800 to 7,798 ft in the Lower Western Himalaya, Mussoorie Range. It encompasses considerable forested area, Banj Oak (Quercus leucotrichophora) with intermittent Deodars, Pines and Rhododendrons. The present paper reveals floristic diversity medicinally important plant species Landour, Mussoorie. During study 97 vascular plants (Angiosperms Gymnosperms) belonging 54 families were recorded from area. There 24 tree species, 44 herbs, shrubs, 5 climbers. major Angiosperms are Asteraceae (8 genera, 9 species), followed by Rosaceae (5 6 Lamiaceae (3 4 species) genera Pinaceae, Acanthaceae, Polygonaceae, 3 Cornaceae, Sapindaceae, Urticaceae. majority percentage ground cover comprised herbs. A total 74 identified which have properties among 20 trees, 16 36 herbs 2 All enumerated botanical names, common family, habit, properties.

Language: Английский

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Antioxidant activity and myco-chemical profiling of Campylospora parvula Kuzuha isolated from the roots of Rubus ellipticus

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: July 29, 2024

Endophytic fungi are important sources of various bioactive natural compounds. Present work elucidates the antioxidant activity and chemical characterization Campylospora parvula Kuzuha isolated from roots ethno medicinal plant Rubus ellipticus. Antioxidant activities were tested using DPPH, MCA FRAP assays, total phenolic flavonoid content by Folin-Ciocalteu aluminum chloride method, respectively. Chemical profile ethyl acetate extract was illustrated Gas chromatography mass spectrometry (GC-MS) analysis. The of C. presents IC50, 47.75±3.6 µg/ml for 53.36±2.6 360.54±8.6 AAE/g dry assay. GCMS analysis revealed presence Octanal, 2-(phenylmethylene)- (16.24%), 1-(4-Iopropylphenyl)-2-methylpropyl (12.91%), Benzoic acid, 2-hydroxy-, phenylmethyl ester (11.85%) as major Findings present study promising keenly hopeful further research on individual compound to assess their potential, especially in pharmacology sector.

Language: Английский

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