Green Synthesis of Gold Nanoparticles Using Plant Extracts as Beneficial Prospect for Cancer Theranostics

Molecules, Journal Year: 2021, Volume and Issue: 26(21), P. 6389 - 6389

Published: Oct. 22, 2021

Gold nanoparticles (AuNPs) have been widely explored and are well-known for their medical applications. Chemical physical synthesis methods a way to make AuNPs. In any case, the hunt other more ecologically friendly cost-effective large-scale technologies, such as environmentally biological processes known green synthesis, has gaining interest by worldwide researchers. The international focus on nanotechnology research resulted in various nanomaterials being used physiologically acceptable Several advantages over conventional chemical (simple, one-step approach synthesize, cost-effectiveness, energy efficiency, biocompatibility) drawn scientists’ attention exploring of AuNPs exploiting plants’ secondary metabolites. Biogenic approaches, mainly plant-based metal nanoparticles, chosen ideal strategy due environmental vivo safety, well ease synthesis. this review, we reviewed use synthesized treatment cancer utilizing phytochemicals found plant extracts. This article reviews producing AuNPs, characterization discusses physiochemical properties. study also recent breakthroughs achievements using different mechanisms action, reactive oxygen species (ROS), mediated mitochondrial dysfunction caspase activation, leading apoptosis, etc., anticancer cytotoxic effects. Understanding underlying therapeutic efficacy will aid developing personalized medicines treatments potential strategy.

Language: Английский

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Application of Green Gold Nanoparticles in Cancer Therapy and Diagnosis

Nanomaterials, Journal Year: 2022, Volume and Issue: 12(7), P. 1102 - 1102

Published: March 27, 2022

Nanoparticles are currently used for cancer theranostics in the clinical field. Among nanoparticles, gold nanoparticles (AuNPs) attract much attention due to their usability and high performance imaging techniques. The wide availability of biological precursors plant-based synthesized AuNPs allows development large-scale production a greener manner. Conventional therapies, such as surgery chemotherapy, have significant limitations frequently fail produce satisfying results. prolonged circulation time, allow easy modification with ligands detected via cell surface receptors, increase uptake through receptor-mediated endocytosis. To exploit these unique features, studies been carried out on use contrast agents X-ray-based techniques (i.e., computed tomography). As nanocarriers, by nontoxic biocompatible plants deliver therapeutic biomolecules could be stride forward effective treatment various cancers. Fluorescent-plant-based markers, including AuNPs, fabricated using Medicago sativa, Olax Scandens, H. ambavilla, lanceolatum, detecting Moreover, green extracts applied different types solid tumors. However, cytotoxicity primarily depends size, reactivity, area. In this review, benefits materials therapy firstly explained. Then, considering valuable position medicine, application detection is highlighted an emphasis faced NPs drug delivery platforms.

Language: Английский

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Role of agrochemical-based nanomaterials in plants: biotic and abiotic stress with germination improvement of seeds

Plant Growth Regulation, Journal Year: 2022, Volume and Issue: 97(2), P. 375 - 418

Published: Jan. 4, 2022

Language: Английский

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Green Synthesis of Nanoparticles and Their Energy Storage, Environmental, and Biomedical Applications

Crystals, Journal Year: 2023, Volume and Issue: 13(11), P. 1576 - 1576

Published: Nov. 8, 2023

Green synthesis offers a superior alternative to traditional methods for producing metal and oxide nanoparticles. This approach is not only benign safe but also cost-effective, scalable, straightforward, operating under ambient conditions. Notable metals nanoparticles, such as manganese oxides, iron silver, gold, have been produced using various bio-reductants derived from plant extracts. These biological agents expedite the reduction process stabilize serving dual roles reducing capping agents. review presents green of nanoparticles (NPs) obtained biogenic wastes The green-synthesized nanostructured MnO2 are evaluated potential photocatalyst water treatment an electrode material in lithium-ion batteries supercapacitors. green-derived examined promising antioxidant, anti-inflammatory, anti-diabetic Additionally, this discusses precious specifically silver (Ag NPs) gold (Au NPs), highlighting their medical applications areas like antiviral treatments cancer therapy.

Language: Английский

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Recent Advances in Green Synthesis, Characterization, and Applications of Bioactive Metallic Nanoparticles

Pharmaceuticals, Journal Year: 2022, Volume and Issue: 15(4), P. 455 - 455

Published: April 8, 2022

Nanoparticles (NPs) are elements derived from a cluster of atoms with one or more dimensions in the nanometer scale range 1-100 nm. The bio nanofabrication metallic NPs is now an important dynamic area research, major significance applied research. Biogenic synthesis desirable than physical and chemical due to its eco-friendliness, non-toxicity, lower energy consumption, multifunctional nature. Plants outperform microorganisms as reducing agents they contain large secondary biomolecules that accelerate reduction stability NPs. produced can then be studied spectroscopically (UV-Visible, XRD, Raman, IR, etc.) microscopically (SEM, TEM, AFM, etc.). biological ion oxide nanoparticle quick, simple, may scaled up at room temperature pressure. rise multi-drug resistant (MDR) microbes immoderate use antibiotics non-infected patients cause morbidity mortality humans. contemporary development new class different mechanisms action kill crucial. Metals their oxides extremely toxic unprecedentedly low concentrations. In addition, prevailing infections plants animals raising significant concerns across globe. NPs' wide bioactivity makes them ideal antimicrobial agricultural medical fields. present review outlines botanicals, which enables metals stabilized form even after ionization. It also presents valuable database on biofunctionalization synthesized for further drug development.

Language: Английский

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Nano/microencapsulation of plant biocontrol agents by chitosan, alginate, and other important biopolymers as a novel strategy for alleviating plant biotic stresses

International Journal of Biological Macromolecules, Journal Year: 2022, Volume and Issue: 222, P. 1589 - 1604

Published: Oct. 4, 2022

Language: Английский

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Agricultural wastes: A practical and potential source for the isolation and preparation of cellulose and application in agriculture and different industries

Industrial Crops and Products, Journal Year: 2023, Volume and Issue: 208, P. 117904 - 117904

Published: Dec. 12, 2023

Cellulose is an organic compound belonging to polysaccharides. This biopolymer made of glucose subunits. plays essential role in the structure and strength plants. polymer has biodegradable, biocompatible, renewable properties. Agricultural wastes are excellent sources for cellulose extraction. lignocellulosic materials, lignin main components these wastes. Millions tons agricultural waste thrown away burned yearly. large amount leads environmental pollution energy resources. Upgrading such by developing innovative products as nanomaterials nanocomposites can have high economic benefits. The intelligent use a rich source be primarily responsible increase population industrialization countries. Optimal extraction from widely used various fields agriculture, industry, medicine, energy. Different chemical, physical, physicochemical, biological methods been presented extract its derivatives waste. In this review, we will discuss position importance cellulose, extracted agrarian sources.

Language: Английский

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Green synthesis of ZnFe2O4 nanoparticles using plant extracts and their applications: A review

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 872, P. 162212 - 162212

Published: Feb. 14, 2023

Language: Английский

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Micro-/Nano-Carboxymethyl Cellulose as a Promising Biopolymer with Prospects in the Agriculture Sector: A Review

Polymers, Journal Year: 2023, Volume and Issue: 15(2), P. 440 - 440

Published: Jan. 13, 2023

The increase in the population rate has increased demand for safe and quality food products. However, current agricultural system faces many challenges producing vegetables fruits. Indiscriminate use of pesticides fertilizers, deficiency water resources, short shelf life products postharvest, nontargeted delivery agrochemicals are main challenges. In this regard, carboxymethyl cellulose (CMC) is one most promising materials agriculture sector minimizing these due to its mechanical strength, viscosity, wide availability, edibility properties. CMC also high absorbency; therefore, it can be used (as superabsorbent hydrogels). Due hydroxyl groups on surface, substance efficacy removing pollutants, such as heavy metals. Enriching coatings with additional substances, antimicrobial, antibrowning, antioxidant, antisoftening materials, provide further novel formulations unique advantages. addition, encapsulation bioactive or provides a targeted system. This review presents comprehensive overview applications preserving fruit vegetable quality, remediating pollution, sources, encapsulating molecules delivery.

Language: Английский

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Advancing sustainable agriculture: a critical review of smart and eco-friendly nanomaterial applications

Journal of Nanobiotechnology, Journal Year: 2023, Volume and Issue: 21(1)

Published: Oct. 11, 2023

Undoubtedly, nanoparticles are one of the ideal choices for achieving challenges related to bio sensing, drug delivery, and biotechnological tools. After gaining success in biomedical research, scientists exploring various types sustainable agriculture. The active can be used as a direct source micronutrients or delivery platform delivering bioactive agrochemicals improve crop growth, yield, quality. Till date, several reports have been published showing applications nanotechnology For instance, methods employed application nanoparticles; especially metal physicochemical properties such core synthesize nanoparticles, their size, shape, surface chemistry, coatings affect crops, soil health, crop-associated ecosystem. Therefore, selecting with appropriate applying them agriculture via suitable method stands smart option achieve improved plant performance. In presented review, we compared nanoparticle plants critically interpreted significant differences find out relatively safe specific agricultural practice. Further, analyzed discussed different that influence on terms nano safety nanotoxicity. From literature would like point implementation smaller sized low concentration seed priming foliar spray could safer minimizing nanotoxicity, exhibiting better performance during stress non-stressed conditions. Moreover, using nanomaterials pose alternative conventional chemical fertilizers cleaner technology While reviewing all available literature, came across some serious drawbacks lack proper regulatory bodies control usage poor knowledge long-term impact ecosystem which need addressed near future comprehensive applicability green

Language: Английский

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