Review on Nanoparticles and Nanostructured Materials: Bioimaging, Biosensing, Drug Delivery, Tissue Engineering, Antimicrobial, and Agro-Food Applications

Nanomaterials, Journal Year: 2022, Volume and Issue: 12(3), P. 457 - 457

Published: Jan. 28, 2022

In the last few decades, vast potential of nanomaterials for biomedical and healthcare applications has been extensively investigated. Several case studies demonstrated that can offer solutions to current challenges raw materials in fields. This review describes different nanoparticles nanostructured material synthesis approaches presents some emerging biomedical, healthcare, agro-food applications. focuses on various nanomaterial types (e.g., spherical, nanorods, nanotubes, nanosheets, nanofibers, core-shell, mesoporous) be synthesized from their bioimaging, biosensing, drug delivery, tissue engineering, antimicrobial, agro-foods. Depending morphology size, aspect ratio, geometry, porosity), used as formulation modifiers, moisturizers, nanofillers, additives, membranes, films. As toxicological assessment depends sizes morphologies, stringent regulation is needed testing efficient dosages. The perspectives an industrial breakthrough are related optimization production processing conditions.

Language: Английский

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Nanoparticle and Nanostructure Synthesis and Controlled Growth Methods

Nanomaterials, Journal Year: 2022, Volume and Issue: 12(18), P. 3226 - 3226

Published: Sept. 16, 2022

Nanomaterials are materials with one or more nanoscale dimensions (internal external) (i.e., 1 to 100 nm). The nanomaterial shape, size, porosity, surface chemistry, and composition controlled at the nanoscale, this offers interesting properties compared bulk materials. This review describes how nanomaterials classified, their fabrication, functionalization techniques, growth-controlled mechanisms. First, history of is summarized then different classification methods, based on dimensionality (0–3D), (carbon, inorganic, organic, hybrids), origin (natural, incidental, engineered, bioinspired), crystal phase (single phase, multiphase), dispersion state (dispersed aggregated), presented. Then, synthesis methods discussed classified in function starting material (bottom-up top-down), reaction (gas, plasma, liquid, solid), nature dispersing forces (mechanical, physical, chemical, physicochemical, biological). Finally, challenges synthesizing for research commercial use highlighted.

Language: Английский

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Nanomaterials: A comprehensive review of applications, toxicity, impact, and fate to environment

Journal of Molecular Liquids, Journal Year: 2022, Volume and Issue: 370, P. 121046 - 121046

Published: Dec. 12, 2022

Language: Английский

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Carbon-Based Stimuli-Responsive Nanomaterials: Classification and Application

Cyborg and Bionic Systems, Journal Year: 2023, Volume and Issue: 4

Published: Jan. 1, 2023

Carbon-based nanomaterials, including carbon nanotubes, nanospheres, and nanofibers, are becoming a research hotspot due to their unique structure good mechanical, thermal, electrical, optical, chemical properties. With the development of material synthesis technology, they can be functionalized used in various fields such as energy, environment, biomedicine. In particular, stimuli-responsive carbon-based nanomaterials have stood out recent years because smart behavior. Researchers applied different disease treatments based on stimulus-response this paper, nanomaterials' morphology, we categorize them into nanofibers according morphology. Then, applications probes, bioimaging, tumor therapy, other discussed. Finally, address advantages disadvantages discuss future perspective.

Language: Английский

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Modern designs of electrochemical sensor platforms for environmental analyses: Principles, nanofabrication opportunities, and challenges

Trends in Environmental Analytical Chemistry, Journal Year: 2023, Volume and Issue: 38, P. e00199 - e00199

Published: Feb. 11, 2023

In recent decades, much attention has been paid to using nanomaterials in the development of highly-sensitive sensors for environmental monitoring. This review describes how are being used develop electrochemical sensing platforms analysis (air pollution, water quality, soil nutrients, and pathogens). particular, we discuss use nanofabrication techniques (e.g., monolayer self-assembly, drop-casting, molecular imprinting, electrodeposition, situ polymerization, hydrogenation, 3D printing) fabrication high-sensitive electrodes is addressed. The potential carbon, organic, inorganic, hybrid enable automation, real-time detection, multiplexed test also Recent applications mobile, disposable, wearable, implantable, self-powered monitoring ions, particles, compounds, microorganisms, contaminants real samples covered. Finally, opportunities challenges high-performance optimizing their performance testing highlighted. All data only avilable this article

Language: Английский

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Antibiotic resistant bacteria: current situation and treatment options to accelerate the development of a new antimicrobial arsenal

Expert Review of Anti-infective Therapy, Journal Year: 2022, Volume and Issue: 20(8), P. 1095 - 1108

Published: May 16, 2022

Antibiotic resistance is one of the biggest public health threats worldwide. Currently, antibiotic-resistant bacteria kill 700,000 people every year. These data represent near future in which we find ourselves, a 'post-antibiotic era' where identification and development new treatments are key. This review focused on current emerging antimicrobial therapies can solve this global threat.Through literature search using databases such as Medline Web Science, engines Google Scholar, different were analyzed, including pathogen-oriented therapy, phagotherapy, microbiota antivirulent therapy. Additionally, pathways antibiotics described, emphasizing potential advantages that combination drug repurposing strategy with application mathematical prediction models could bring to problem AMRs.This offers several starting points single problem: reducing number AMR. The suggest strategies described provide many benefits improve treatments. However, antimicrobials remains necessary. Drug repurposing, models, considered be interest due its rapid effective increase therapeutic arsenal.Antibiotic currently Right now, Many available useless against resistant bacteria. present ourselves post-antibiotic era, have unable combat bacterial infections emerging. In review, published studies accessed explore techniques existing treatment options. these cannot replace antibiotic reviewed knowledge presents alternatives adjuvants Therefore, research into important. exposes known drugs contribute cost-effective faster way compared traditional methods antibiotics. emphasizes urgency identifying pharmacological targets aid therapies, alternative therapies. greatly shorten time cost adds value certain commercialized molecules, recovering part investment made by pharmaceutic industry. addition, it provides greater about other mechanisms develop resistance.

Language: Английский

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Bioinspired nanotopographical design of drug delivery systems

Nature Reviews Bioengineering, Journal Year: 2023, Volume and Issue: 1(2), P. 139 - 152

Published: Jan. 26, 2023

Effective drug delivery is important in the treatment of various biomedical conditions, ranging from autoimmune disorders to cancer and bacterial infections. Nanostructured systems can help overcome challenges efficient such as poor distribution, inefficient penetration across biological barriers off-target effects. The bioinspired nanotopography carrier surfaces provides a physical cue modulate their interaction with systems. In this Review, we discuss how naturally occurring nanotopographical inspire design biomaterials for delivery. We highlight nanoscale surface modifications carriers fabrication strategies, followed by discussion about biointerfaces regulate functions. Key functionalities include bio-adhesion, barrier remodelling, uptake subcellular trafficking, cellular signalling modulation, antimicrobial interfaces. Finally, provide an outlook on future applications delivery, focus key exciting opportunities bench bedside. Three-dimensional plays role components. This Review discusses nanotopographies that improve muco-adhesion cyto-adhesion, modulation activities platforms.

Language: Английский

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Green synthesis and characterization of silver nanoparticles for reducing the damage to sperm parameters in diabetic compared to metformin

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: Feb. 8, 2023

The present study used physics to synthesize silver nanoparticles using aqueous extract of fresh garlic as reducing and a stabilizing agent nitrate solution. This method has proven be environmentally friendly safe for the synthesis stable nanoparticles. acquisition was confirmed by optical detection, that is, changing color liquid transparent orange then blackish brown. Then, characterization other assays. In this study, it found absorption peak at wavelength 420 nm particle size ranged between [50-350] nm. surface roughness oxide/silver 9.32 with an average square 21.19 nm, energy dispersive spectra showed in region 3 keV, indicating contained crystalline silver. stability good, ZP reached (- 19.5). results confirm conductivity increases increase frequency due high photons, which causes electrons vibrate levels thus mitochondria movement sperm Diabetic mice treated doses toxic effect been evaluated studies, addition evaluating antioxidants, antifungals, treating cancer cells, regulating cholesterol levels, these on sex cells pregnant female mice, heart tension, many tests. activities efficacy sperms were determined male diabetes caused STZ, treatment period long (35 days) so evaluation complete life cycle within time nano size. not studied previous studies. indicate biosynthesis plant led positive treatments contributing number reactivation decrease abnormalities mortality diabetes. is evidence (50-350 nm) can treat impotence future diseases without side effects.

Language: Английский

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Pharmaceuticals in Water: Risks to Aquatic Life and Remediation Strategies

Hydrobiology, Journal Year: 2023, Volume and Issue: 2(2), P. 395 - 409

Published: June 14, 2023

The presence of pharmaceuticals in the aquatic environment presents a challenge to modern science. most significant impact this can induce is emergence antibiotic resistance, which lead global health emergency. It important note that not limited resistance. Pharmaceuticals also affect behaviour and reproductive systems organisms, with cascading effects on entire ecosystems. Numerous studies have reported due uncontrolled disposal polluted domestic, agricultural, industrial wastewater water bodies. This work discusses potential one hand are highly for mankind, yet their non-judicious usage equally intriguing problematic conditions systems. Pathways through pharmaceutics make way into bodies discussed. Furthermore, risk imposed by life elaborated. possible pragmatic remediation methods pharmaceutical products be treated Emphasis placed phytoremediation advanced oxidative process, factors affecting efficacy these

Language: Английский

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Recent advances in the application of nanomaterials for improved biodiesel, biogas, biohydrogen, and bioethanol production

Fuel, Journal Year: 2023, Volume and Issue: 358, P. 130261 - 130261

Published: Nov. 4, 2023

Language: Английский

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