Journal of Drug Delivery and Therapeutics,
Journal Year:
2024,
Volume and Issue:
14(12), P. 181 - 190
Published: Dec. 15, 2024
Infectious
diseases,
including
COVID-19,
malaria,
tuberculosis,
and
sexually
transmitted
diseases
(STDs),
pose
significant
threats
to
global
health.
Nanotechnology
has
emerged
as
a
promising
tool
in
the
diagnosis,
treatment,
prevention
of
these
diseases.
This
review
highlights
applications
nanotechnology
combating
infectious
Nanoparticles,
such
metallic
nanoparticles,
liposomes,
quantum
dots,
have
been
employed
detection
treatment
Nanotechnology-based
drug
delivery
systems
improved
efficacy
reduced
toxicity
antiviral
antibacterial
drugs.
Additionally,
enabled
development
point-of-care
diagnostics
vaccines
for
provides
an
overview
current
state
disease
management
its
potential
revolutionize
field.
By
leveraging
unique
properties
can
provide
innovative
solutions
ultimately
improving
health
outcomes.
Keywords:
Nanotechnology,
Malaria,
Tuberculosis,
HIV/AIDS
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2024,
Volume and Issue:
12
Published: July 11, 2024
Cancer,
being
one
of
the
deadliest
diseases,
poses
significant
challenges
despite
existence
traditional
treatment
approaches.
This
has
led
to
a
growing
demand
for
innovative
pharmaceutical
agents
that
specifically
target
cancer
cells
effective
treatment.
In
recent
years,
use
metal
nanoparticles
(NPs)
as
promising
alternative
conventional
therapies
gained
prominence
in
research.
Metal
NPs
exhibit
unique
properties
hold
tremendous
potential
various
applications
Studies
have
demonstrated
certain
metals
possess
inherent
or
acquired
anticancer
capabilities
through
their
surfaces.
These
make
an
attractive
focus
therapeutic
development.
this
review,
we
will
investigate
applicability
several
distinct
classes
tumor
targeting
may
include
gold,
silver,
iron
oxide,
and
other
with
can
be
exploited
purposes.
Additionally,
provide
comprehensive
summary
risk
factors
associated
application
NPs.
Understanding
addressing
these
crucial
successful
clinical
translation
mitigate
any
failures
NP-based
therapies.
By
exploring
identifying
factors,
review
aims
contribute
advancement
strategies.
The
anticipated
outcome
is
valuable
insights
pave
way
targeted
utilizing
patients.
Sensors and Actuators A Physical,
Journal Year:
2024,
Volume and Issue:
376, P. 115625 - 115625
Published: June 24, 2024
The
integration
of
CRISPR
technology
with
microfluidic-based
biosensors
has
greatly
expanded
its
applications
in
medicine
and
molecular
biology.
This
combination
offers
enhanced
sensitivity
selectivity
medical
diagnostics.
CRISPR-powered
microfluidics
enables
the
accurate
quantification
DNA
RNA
associated
diseases
such
as
cancer,
viral
infections,
bacterial
diseases.
precise
targeting
capabilities
allow
for
detection
specific
genetic
sequences,
aiding
early
diagnosis,
disease
monitoring,
treatment
assessment.
improves
specificity
by
leveraging
programmable
nature
coupling
it
signal
readouts.
However,
challenges
assay
optimization,
standardization,
device
fabrication
need
to
be
addressed.
Additionally,
complexity
presents
potential
limitations
terms
off-target
effects
unintended
modifications.
Overall,
holds
tremendous
diagnostics,
but
further
research
development
are
required
fully
exploit
benefits
clinical
settings.
Critical Reviews in Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 25
Published: Sept. 17, 2024
This
comprehensive
review
delves
into
the
advancements
and
challenges
in
biosensing,
with
a
strong
emphasis
on
transformative
potential
of
CRISPR
technology
for
early
rapid
detection
infectious
diseases.
It
underscores
versatility
CRISPR/Cas
systems,
highlighting
their
ability
to
detect
both
nucleic
acids
non-nucleic
acid
targets,
seamless
integration
isothermal
amplification
techniques.
The
provides
thorough
examination
latest
developments
CRISPR-based
biosensors,
detailing
unique
properties
such
as
high
specificity
programmability,
which
make
them
particularly
effective
detecting
disease-associated
acids.
While
focuses
due
its
critical
role
diagnosing
diseases,
it
also
explores
broader
applications
thereby
acknowledging
technology's
potential.
Additionally,
identifies
existing
challenges,
need
improved
signal
real-world
applicability,
offers
future
perspectives
aimed
at
overcoming
these
hurdles.
ultimate
goal
is
advance
development
highly
sensitive
specific
biosensors
that
can
be
used
widely
improving
human
health,
point-of-care
settings
resource-limited
environments.
Biomedical Physics & Engineering Express,
Journal Year:
2024,
Volume and Issue:
10(5), P. 052002 - 052002
Published: Aug. 14, 2024
Abstract
Purpose
.
This
review
aims
to
highlight
current
improvements
in
microfluidic
devices
designed
for
digestive
cancer
simulation.
The
emphasizes
the
use
of
multicellular
3D
tissue
engineering
models
understand
complicated
biology
tumor
microenvironment
(TME)
and
progression.
purpose
is
develop
oncology
research
improve
patients’
lives.
Methods
analyzes
recent
on
mimicking
cancer.
It
uses
tissue-engineered
devices,
notably
organs
a
chip
(OOC),
simulate
human
organ
function
lab.
Cell
cultivation
modern
three-dimensional
hydrogel
platforms
allows
precise
geometry,
biological
components,
physiological
qualities.
novel
methodologies,
key
findings,
technical
progress
explain
this
field’s
advances.
Results
study
discusses
advances
Micro
systems
with
are
emphasized.
These
capture
complex
biochemical
gradients,
niche
variables,
dynamic
cell–cell
interactions
(TME).
reveal
stomach
progression
by
duplicating
TME.
Recent
discoveries
technology
have
improved
our
understanding
gut
biology,
as
shown
review.
Conclusion
Microfluidic
play
crucial
role
modeling
furthering
research.
could
transform
drug
development
treatment
revealing
provides
complete
summary
suggests
future
field
professionals.
review’s
major
goal
further
medical
Nanotechnology,
Journal Year:
2024,
Volume and Issue:
35(39), P. 392002 - 392002
Published: June 28, 2024
Tissue
engineering
is
a
multidisciplinary
field
that
merges
engineering,
material
science,
and
medical
biology
in
order
to
develop
biological
alternatives
for
repairing,
replacing,
maintaining,
or
boosting
the
functionality
of
tissues
organs.
The
ultimate
goal
tissue
create
enhancing
However,
current
landscape
techniques
presents
several
challenges,
including
lack
suitable
biomaterials,
inadequate
cell
proliferation,
limited
methodologies
replicating
desired
physiological
structures,
unstable
insufficient
production
growth
factors,
which
are
essential
facilitating
communication
appropriate
cellular
responses.
Despite
these
there
has
been
significant
progress
made
recent
years.
Nanoparticles
hold
major
role
within
realm
nanotechnology
due
their
unique
qualities
change
with
size.
These
particles,
provide
potential
solutions
issues
met
have
helped
propel
its
state
prominence.
substantial
breakthroughs
utilization
nanoparticles
over
past
two
decades,
full
range
addressing
difficulties
remains
largely
untapped.
This
fact
advancements
occurred
relatively
isolated
pockets.
In
purpose
this
research
conduct
an
in-depth
investigation
ways
various
types
might
be
put
use.
addition
this,
it
sheds
light
on
challenges
need
conquered
unlock
maximum
area.
Biomedical Materials,
Journal Year:
2024,
Volume and Issue:
19(5), P. 052004 - 052004
Published: July 29, 2024
Quantum
dots
(QDs)
are
with
exceptional
physicochemical
and
biological
properties,
making
them
highly
versatile
for
a
wide
range
of
applications
in
cancer
therapy.
One
the
key
features
QDs
is
their
unique
electronic
structure,
which
gives
functional
attributes.
Notably,
photoluminescence
can
be
strong
adjustable,
allowing
to
effectively
used
fluorescence
based
diagnosis
such
as
biosensing
bioimaging.
In
addition,
demonstrate
an
impressive
capacity
loading
cargo,
ideal
drug
delivery
applications.
Moreover,
ability
absorb
incident
radiation
positions
promising
candidates
cancer-killing
techniques
like
photodynamic
The
objective
this
comprehensive
review
present
current
overview
recent
advancements
utilizing
multifunctional
innovative
biomaterials.
This
focuses
on
elucidating
biological,
electronic,
properties
QDs,
along
discussing
technical
QD
synthesis.
Furthermore,
it
thoroughly
explores
progress
made
biosensing,
bioimaging,
therapy
including
necrosis,
highlighting
significant
potential
field
treatment.
addresses
limitations
associated
provides
valuable
insights
into
future
directions,
thereby
facilitating
further
field.
By
presenting
well-structured
overview,
serves
authoritative
informative
resource
that
guide
research
endeavors
foster
continued
Nanomaterials,
Journal Year:
2023,
Volume and Issue:
13(3), P. 483 - 483
Published: Jan. 25, 2023
Microbes
have
dominated
life
on
Earth
for
the
past
two
billion
years,
despite
facing
a
variety
of
obstacles.
In
20th
century,
antibiotics
and
immunizations
brought
about
these
changes.
Since
then,
microorganisms
acquired
resistance,
various
infectious
diseases
been
able
to
avoid
being
treated
with
traditionally
developed
vaccines.
Antibiotic
resistance
pathogenicity
surpassed
antibiotic
discovery
in
terms
importance
over
course
few
decades.
These
shifts
resulted
tremendous
economic
health
repercussions
across
board
all
socioeconomic
levels;
thus,
we
require
ground-breaking
innovations
effectively
manage
microbial
infections
provide
long-term
solutions.
The
pharmaceutical
biotechnology
sectors
radically
altered
as
result
nanomedicine,
this
trend
is
now
spreading
antibacterial
research
community.
Here,
examine
role
that
nanomedicine
plays
prevention
infections,
including
topics
such
diagnosis,
antimicrobial
therapy,
administration,
immunizations,
well
opportunities
challenges
lie
ahead.
