Nanoscale,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 2, 2024
A
novel
water-soluble
polymer
nanocomposite
with
ultra-small
iron
oxide
nanoparticles
intercalated
into
a
biocompatible
matrix
of
1-vinyl-1,2,4-triazole
and
N
-vinylpyrrolidone
copolymer
exhibits
pronounced
antibacterial
antibiofilm
activity.
ACS Omega,
Journal Year:
2024,
Volume and Issue:
9(31), P. 33303 - 33334
Published: July 25, 2024
The
increasing
occurrence
of
infectious
diseases
caused
by
antimicrobial
resistance
organisms
urged
the
necessity
to
develop
more
potent,
selective,
and
safe
agents.
unique
magnetic
tunable
properties
iron
oxide
nanoparticles
(IONPs)
make
them
a
promising
candidate
for
different
theragnostic
applications,
including
Though
IONPs
act
as
nonspecific
agent,
their
activities
are
directly
or
indirectly
linked
with
synthesis
methods,
synthesizing
precursors,
size,
shapes,
concentration,
surface
modifications.
Alteration
these
parameters
could
accelerate
decelerate
production
reactive
oxygen
species
(ROS).
An
increase
in
ROS
role
disrupts
bacterial
cell
walls,
membranes,
alters
major
biomolecules
(e.g.,
lipids,
proteins,
nucleic
acids),
affects
metabolic
processes
Krebs
cycle,
fatty
acid
synthesis,
ATP
glycolysis,
mitophagy).
In
this
review,
we
will
investigate
antibacterial
activity
bare
surface-modified
influence
physiochemical
on
activity.
Additionally,
report
potential
mechanism
IONPs'
action
driving
Frontiers in Chemistry,
Journal Year:
2025,
Volume and Issue:
12
Published: Jan. 15, 2025
Microorganisms
are
becoming
resistant
to
drugs
and
antimicrobials,
making
it
a
significantly
critical
global
issue.
Nosocomial
infections
resulting
in
alarmingly
increasing
rates
of
morbidity
mortality.
Plant
derived
compounds
hold
numerous
antimicrobial
properties,
them
very
capable
source
counteract
microbial
strains.
Syzygium
aromaticum
(Clove)
extract
has
been
proven
by
studies
contain
active
ingredients
that
demonstrate
antibacterial,
antifungal,
antioxidant,
insecticidal
properties.
It
also
used
historically
for
its
pain
relief
especially
tooth
ache.
Clove
nanoparticle
synthesis
is
promising
method
combining
therapeutics
with
metals
at
nanoscale.
Such
nanostructured
systems
combination
the
heterocyclic
antibiotic
clarithromycin
could
potentiate
action
plant
extracts,
decrease
drug
side
effects
improve
activity.
In
this
study,
clove
(C)
was
successfully
synthesize
silver
nanoparticles
(AgNP)
create
AgNPC
AgNPCA
(A
=
clarithromycin).
The
two
underwent
different
analytical
methods
consisting
SEM,
EDS,
DLS,
UV-vis,
FTIR
XRD.
These
were
against
variety
10
pathogens
exhibited
good
intermediate
antibacterial
resulted
better
properties
smaller
size.
This
study
demonstrates
potential
mediated
AgNP
without
clarithromycin.
AMB Express,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: Aug. 16, 2024
Abstract
The
biosynthesis
of
iron
oxide
nanoparticles
has
received
increasing
attention
in
the
field
food
nanotechnology
because
their
non-toxicity,
high
efficiency,
antibacterial
power,
and
decontamination
features.
Therefore,
(nFe)
was
prepared
from
leaves
some
vegetables,
such
as
cabbage
(C)
turnips
(T),
well
moringa
(M).
Alcoholic
extracts
these
were
also
tested
on
Staphylococcus
aureus
Escherichia
coli
to
evaluate
activity.
results
revealed
that
particle
sizes
nanomaterials
studied
ranged
12.99
22.72
nm,
particles
spherical,
irregular,
surrounded
by
black
color.
It
contains
many
functional
groups
minerals.
Iron
modified
with
Moringa
oleifera
extract
at
a
concentration
200
ppm
had
highest
phenol
content
compared
other
studied.
TnFe
MnFe
maximum
zone
inhibition
25
mm
24
against
,
respectively.
While
minimum
8.0
observed
for
nFe
.
it
is
recommended
use
agents
stored
foods.
International Journal of Environmental & Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 16
Published: April 24, 2024
The
utilisation
of
a
recently
developed
green
approach
for
synthesising
iron
oxide
nanoparticles
(Fe2O3NPs)
is
highly
promising,
given
its
low
toxicity
and
environmentally
benevolent
attributes.
In
this
investigation,
Fe2O3
NPs
were
produced
through
the
ferric
chloride
hexahydrate,
incorporating
Permelia
perleta
;(lichen)
extract
under
standard
atmospheric
conditions.
development
was
verified
systematic
characterization
process
by
employing
UV
FTIR,
XRD,
FE
SEM
studies.
average
crystallite
size
sample
found
to
be
20
nm
determined
using
Debye
–
Scherrer
equation.
efficacy
as
photocatalyst
in
eliminating
acridine
orange
evaluated,
highlighting
key
factors
such
catalyst
dosage,
initial
dye
concentration,
pH.
Augmenting
quantity
amplified
decolourisation
dyes,
reaching
peak
70%
degradation
at
pH
2
after
h
with
dose
0.9
g/L.
most
pronounced
effect
observed
against
Bacillus
subtilis
(22
mm),
whereas
least
impact
noted
Pseudomonas
aeruginosa
(14
mm).
Furthermore,
underwent
antioxidant
activity
analysis,
revealing
that
1
gm
possesses
equivalent
4.22
mg
ascorbic
acid.
Nanomaterials,
Journal Year:
2024,
Volume and Issue:
14(15), P. 1311 - 1311
Published: Aug. 3, 2024
Antimicrobial
resistance
(AMR)
is
growing
into
a
major
public
health
crisis
worldwide.
The
reducing
alternatives
to
conventional
agents
starve
for
novel
antimicrobial
agents.
Due
their
unique
magnetic
properties
and
excellent
biocompatibility,
iron
oxide
nanoparticles
(IONPs)
are
the
most
preferable
nanomaterials
in
biomedicine,
including
antibacterial
therapy,
primarily
through
reactive
oxygen
species
(ROS)
production.
IONP
characteristics,
size,
shape,
surface
charge,
superparamagnetism,
influence
biodistribution
activity.
External
fields,
foreign
metal
doping,
surface,
shape
modification
improve
effect
of
IONPs.
Despite
few
disadvantages,
IONPs
expected
be
promising
new
generation.