Stress, Inflammation and Metabolic Biomarkers Are Associated with Body Composition Measures in Lean, Overweight, and Obese Children and Adolescents DOI Creative Commons
Eirini Christaki, Panagiota Pervanidou, Ioannis Papassotiriou

et al.

Children, Journal Year: 2022, Volume and Issue: 9(2), P. 291 - 291

Published: Feb. 21, 2022

The aim of this study was to examine the associations between multiple indices stress, inflammation and metabolism vs. body composition parameters in 121 (43 boys, 78 girls) children adolescents, aged 5-15 y. Subjects were divided into two groups: normal weight (N) (N = 40, BMI z-score -0.1923 ± 0.6), overweight/obese (OB) 81, 2.1947 1.4). All subjects completed State-Trait Anxiety Inventory for Children (STAIC) Children's Depression Inventory, underwent cortisol measurements hair, diurnal series saliva, morning serum. Circulating concentrations high sensitivity C-reactive protein (hsCRP) other biomarkers also obtained. Body analysis performed with a clinically validated, advanced bioimpedance apparatus (BIA), while heart rate variability (HRV) measured as stress biomarker by photoplethysmography (PPG). OB group had higher STAIC-state score, waist-to-hip ratio, skeletal muscle mass, total abdominal fat lower percent fat-free mass (FFM) bone density than N group. HRV did not differ groups. In entire population, correlated strongly circulating hsCRP (r 0.397, p 0.001), ferritin, inflammatory biomarkers, well insulin resistance. A strong correlation serum hair observed 0.777, < suggesting interrelation chronic inflammation. Thus, accumulation adolescents associated an elevation clinical laboratory inflammation, BIA-ACC PPG can be utilized direct screening tool assessing overweight- obesity -related health risks adolescents.

Language: Английский

Clinical Practice Guideline for the Evaluation and Treatment of Children and Adolescents With Obesity DOI
Sarah Hampl, Sandra G. Hassink, Asheley Cockrell Skinner

et al.

PEDIATRICS, Journal Year: 2023, Volume and Issue: 151(2)

Published: Jan. 9, 2023

Language: Английский

Citations

680

Childhood and Adolescent Obesity: A Review DOI Creative Commons
Alvina R. Kansra,

Sinduja Lakkunarajah,

M. Susan Jay

et al.

Frontiers in Pediatrics, Journal Year: 2021, Volume and Issue: 8

Published: Jan. 12, 2021

Obesity is a complex condition that interweaves biological, developmental, environmental, behavioral, and genetic factors; it significant public health problem. The most common cause of obesity throughout childhood adolescence an inequity in energy balance; is, excess caloric intake without appropriate expenditure. Adiposity rebound (AR) early risk factor for adulthood. increasing prevalence adolescent associated with rise comorbidities previously identified the adult population, such as Type 2 Diabetes Mellitus, Hypertension, Non-alcoholic Fatty Liver disease (NAFLD), Obstructive Sleep Apnea (OSA), Dyslipidemia. Due to lack single treatment option address obesity, clinicians have generally relied on counseling dietary changes exercise. psychosocial issues may accompany regarding body habitus, this approach can negative results. Teens develop unhealthy eating habits result Bulimia Nervosa (BN), Binge- Eating Disorder (BED), or Night syndrome (NES). Others Anorexia (AN) they attempt restrict their diet overshoot goal “being healthy.” To date, lifestyle interventions shown only modest effects weight loss. Emerging findings from basic science well interventional drug trials utilizing GLP-1 agonists demonstrated success effective loss obese adults, adolescents, pediatric patients. However, there limited data efficacy safety other weight-loss medications children adolescents. Nearly 6% adolescents United States are severely bariatric surgery consideration will be discussed. In summary, paper overview pathophysiology, clinical, psychological implications, options available

Language: Английский

Citations

376

Mediterranean-Like Dietary Pattern Associations With Gut Microbiome Composition and Subclinical Gastrointestinal Inflammation DOI
Williams Turpin, Mei Dong,

Gila Sasson

et al.

Gastroenterology, Journal Year: 2022, Volume and Issue: 163(3), P. 685 - 698

Published: May 26, 2022

Language: Английский

Citations

78

New Insights and Potential Therapeutic Interventions in Metabolic Diseases DOI Open Access
Vicente Javier Clemente‐Suárez, Alexandra Martín-Rodríguez, Laura Redondo-Flórez

et al.

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(13), P. 10672 - 10672

Published: June 26, 2023

Endocrine homeostasis and metabolic diseases have been the subject of extensive research in recent years. The development new techniques insights has led to a deeper understanding mechanisms underlying these conditions opened up avenues for diagnosis treatment. In this review, we discussed rise diseases, especially Western countries, genetical, psychological, behavioral basis role nutrition physical activity single-cell transcriptomics, gut microbiota, epigenetics, advanced imaging techniques, cell-based therapies diseases. Finally, practical applications derived from information are made.

Language: Английский

Citations

58

Social Epidemiology of Cardiometabolic Risk Factors in Early Adolescents DOI Creative Commons
Jason M. Nagata,

Christiane K. Helmer,

Jennifer H Wong

et al.

International Journal of Cardiology Cardiovascular Risk and Prevention, Journal Year: 2025, Volume and Issue: 25, P. 200382 - 200382

Published: March 6, 2025

To estimate associations between sociodemographic factors and cardiometabolic risk among a demographically diverse sample of U.S. adolescents aged 10-14 years. This study analyzed data from the Adolescent Brain Cognitive Development (ABCD) Study (N = 1412), Years 2 3 (2018-2021). Cardiometabolic including hemoglobin A1c cholesterol (total (TC), high-density lipoprotein (HDL-C), non-HDL-C) were assessed. Multivariable linear regression models conducted to (age, sex, race ethnicity, household income, parental education) (hemoglobin A1c, TC, HDL-C, non-HDL-C). The average level was 5.2 % (±0.4 %), TC 156.6 (±28.9) mg/dL, HDL-C 56.0 (±12.9) mg/dL. Out our sample, 0.5 had diabetes ≥ 6.5 7.6 high (≥200 mg/dL), 7.4 low (<40 mg/dL). Older age associated with lower non-HDL-C levels. Male sex higher (beta coefficient [B] 0.04; 95 confidence interval [CI], 0.00, 0.08; p 0.037) (B -3.14; CI, -6.17, -0.11; 0.042) compared female sex. Black Native American ethnicity White race. Higher income HDL-C. population early identified differences in levels that can inform clinical public health interventions.

Language: Английский

Citations

1

Ketogenic Diet, Physical Activity, and Hypertension—A Narrative Review DOI Open Access
Domenico Di Raimondo, Silvio Buscemi,

Gaia Musiari

et al.

Nutrients, Journal Year: 2021, Volume and Issue: 13(8), P. 2567 - 2567

Published: July 27, 2021

Several studies link cardiovascular diseases (CVD) with unhealthy lifestyles (unhealthy dietary habits, alcohol consumption, smoking, and low levels of physical activity). Therefore, the strong need for CVD prevention may be pursued through an improved control risk factors (impaired lipid glycemic profiles, high blood pressure, obesity), which is achievable overall intervention aimed to favor a healthy lifestyle. Focusing on diet, different recommendations emphasize increase or avoid consumption entire classes food, only partly known foreseeable consequences level health. In recent years, ketogenic diet (KD) has been proposed effective lifestyle metabolic syndrome, although beneficial effects weight loss glucose metabolism seems well established, prolonged KD ability perform types exercise influence pressure (BP) levels, both in normotensives hypertensives, are not so understood. The objective this review analyze, basis current evidence, relationship between KD, regular activity, BP.

Language: Английский

Citations

51

Microbiology, flavor formation, and bioactivity of fermented soybean curd (furu): A review DOI
Guanmian Wei, Bimal Chitrakar,

Joe M. Regenstein

et al.

Food Research International, Journal Year: 2022, Volume and Issue: 163, P. 112183 - 112183

Published: Nov. 20, 2022

Language: Английский

Citations

38

The Longitudinal Interplay between Sleep, Anthropometric Indices, Eating Behaviors, and Nutritional Aspects: A Systematic Review and Meta-Analysis DOI Open Access

Martina Grimaldi,

Valeria Bacaro, Vincenzo Natale

et al.

Nutrients, Journal Year: 2023, Volume and Issue: 15(14), P. 3179 - 3179

Published: July 18, 2023

Sleep is fundamental for adolescents' healthy development but undergoes dramatic changes in quantity and quality due to the conflict between biological social rhythms. Insufficient sleep has been associated with worse physical health status irregular eating behaviors adolescents. This review aims systematically synthesize longitudinal associations dimensions (i.e., duration, timing, quality, insomnia symptoms) indicators anthropometric indices, fat percentage, risk of obesity), behaviors, nutritional aspects type diet related intake specific foods nutrients, amount timing food consumption, energy expenditure). A total 28 studies were included. The meta-analytic results showed that longer better lower symptoms BMI percentage shorter duration (<7 h) a higher obesity. Conversely, indices not over time. Limited literature examined bidirectional association their aspects. Such knowledge sheds new light on role health, highlighting need examine further interplay these variables.

Language: Английский

Citations

22

What causes obesity in children and adolescents? DOI Creative Commons
Carlos Alberto Nogueira‐de‐Almeida,

Virgínia Resende Silva Weffort,

Fábio da Veiga Ued

et al.

Jornal de Pediatria, Journal Year: 2023, Volume and Issue: 100, P. S48 - S56

Published: Oct. 31, 2023

To present the different aspects that may be involved in genesis and maintenance of obesity children adolescents.

Language: Английский

Citations

21

Associations of time spent gardening with mental wellbeing and life satisfaction in mid-to-late adulthood DOI
Selma Lunde Fjaestad, Jessica L. Mackelprang, Takemi Sugiyama

et al.

Journal of Environmental Psychology, Journal Year: 2023, Volume and Issue: 87, P. 101993 - 101993

Published: March 11, 2023

Language: Английский

Citations

19