Factors associated with the intrinsic capacity in older adults: A scoping review DOI
Xiaoqin Wei, Yajing Chen,

Jiangxia Qin

et al.

Journal of Clinical Nursing, Journal Year: 2024, Volume and Issue: 33(5), P. 1739 - 1750

Published: Feb. 12, 2024

Abstract Introduction In 2015, the term ‘intrinsic capacity’ (IC) was proposed by World Health Organisation to promote healthy aging. However, factors associated with IC are still discrepant and uncertain. Aim We aim synthesise connected IC. Methods This scoping review followed five‐stage framework of Arksey O'Malley reported using PRISMA‐ScR guidelines. Results all, 29 articles were included. older adults is demographic characteristics, socioeconomic factors, disease conditions, behavioural biomarkers. Age, sex, marital status, occupation education, income/wealth, chronic diseases, hypertension, diabetes, disability, smoking alcohol consumption, physical activity emerged as important related adults. Conclusions shows that multiple factors. Understanding these can provide healthcare personnel theoretical basis for intervening managing in Relevance Clinical Practice The influencing identified help guide maintain their own intrinsic capacity, thereby promoting health well‐being. modifiable also evidence develop targeted intervention strategies delay decline. No Patient or Public Contribution As this a review, no patient public contributions required.

Language: Английский

Epidemiology of sarcopenia: Prevalence, risk factors, and consequences DOI Creative Commons
Shuai Yuan,

Susanna C. Larsson

Metabolism, Journal Year: 2023, Volume and Issue: 144, P. 155533 - 155533

Published: March 11, 2023

Language: Английский

Citations

490
Protein Intake and Sarcopenia in Older Adults: A Systematic Review and Meta-Analysis DOI Open Access
Hélio José Coelho‐Júnior, Riccardo Calvani, Domenico Azzolino

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(14), P. 8718 - 8718

Published: July 18, 2022

Background: The present systematic review and meta-analysis investigated the cross-sectional longitudinal associations between protein intake sarcopenia in older adults. Methods: Observational studies that association as primary or secondary outcome people aged 60 years were included. Studies published languages other than English, Italian, Portuguese, Spanish excluded. retrieved from MEDLINE, SCOPUS, EMBASE, CINAHL, AgeLine, Food Science Source databases through January 31, 2022. A pooled effect size was calculated based on standard mean differences. Results: Five studies, one study, case-control study 3353 community-dwelling adults with a age of approximately 73 four indicated consumed significantly less their peers no sarcopenia. Conclusions: Results suggest an inadequate might be associated

Language: Английский

Citations

74
Sarcopenia DOI
Avan Aihie Sayer, Rachel Cooper, Hidenori Arai

et al.

Nature Reviews Disease Primers, Journal Year: 2024, Volume and Issue: 10(1)

Published: Sept. 19, 2024

Language: Английский

Citations

34
Using network pharmacology and molecular docking technology, proteomics and experiments were used to verify the effect of Yigu decoction (YGD) on the expression of key genes in osteoporotic mice DOI Creative Commons

Kun Yan,

Ruikun Zhang, Jiaxin Wang

et al.

Annals of Medicine, Journal Year: 2025, Volume and Issue: 57(1)

Published: Jan. 3, 2025

Yigu decoction (YGD) is a traditional Chinese medicine prescription for the treatment of osteoporosis, although many clinical studies have confirmed its anti-OP effect, but specific mechanism still not completely clear.

Language: Английский

Citations

3
Osteoporosis and sarcopenia-related traits: A bi-directional Mendelian randomization study DOI Creative Commons
Chao Liu, Ningyuan Liu, Yu Xia

et al.

Frontiers in Endocrinology, Journal Year: 2022, Volume and Issue: 13

Published: Sept. 14, 2022

With the advancement of world population aging, age-related osteoporosis (OP) and sarcopenia (SP) impose enormous clinical economic burden on society. Evidence from accumulating studies indicates that they mutually influence one another. However, an observational study may be affected by potential confounders. Meanwhile, a Mendelian randomization (MR) can overcome these confounders to assess causality.The aim this was evaluate causality between OP SP, informing new strategies for prevention, diagnosis, treatment osteosarcopenia.Instrumental variables (IVs) at genome-wide significance level were obtained published summary statistics, inverse variance weighted method several other MR methods conducted bi-directional SP OP. Myopia analyzed as negative control outcome test validity IVs.Femoral neck bone mineral density (FN BMD), lumbar spine BMD (LS forearm (FA BMD) had direct causal effect appendicular lean mass (ALM) [FA BMD-related analysis: odds ratio (OR) = 1.028, 95% confidence interval (CI) (1.008,1.049), p 0.006; FN OR (95% CI) 1.131 (1.092,1.170), 3.18E-12; LS 1.080 (1.062,1.098), 2.86E-19]. ALM significant [OR (1.033,1.147), 0.001]. There no evidence association low grip strength.OP might have each other. Our results supported idea patient with severe more susceptible lose loss reduce BMD.

Language: Английский

Citations

45
Factors Associated With Social Isolation in Older Adults: A Systematic Review and Meta-Analysis DOI
Zhifei Wen, Sihan Peng, Liping Yang

et al.

Journal of the American Medical Directors Association, Journal Year: 2022, Volume and Issue: 24(3), P. 322 - 330.e6

Published: Dec. 20, 2022

Language: Английский

Citations

39
Identification and Characterization of Genomic Predictors of Sarcopenia and Sarcopenic Obesity Using UK Biobank Data DOI Open Access
Ekaterina A. Semenova, Erinija Pranckevičienė, Э. А. Бондарева

et al.

Nutrients, Journal Year: 2023, Volume and Issue: 15(3), P. 758 - 758

Published: Feb. 2, 2023

The substantial decline in skeletal muscle mass, strength, and gait speed is a sign of severe sarcopenia, which may partly depend on genetic risk factors. So far, hundreds genome-wide significant single nucleotide polymorphisms (SNPs) associated with handgrip lean mass walking pace have been identified the UK Biobank cohort; however, their pleiotropic effects all three phenotypes not investigated. By combining summary statistics association studies (GWAS) pace, we 78 independent SNPs (from 73 loci) traits consistent effect directions. Of SNPs, 55 were also body fat percentage 25 type 2 diabetes (T2D), indicating that obesity T2D share many common alleles. Follow-up bioinformatic analysis revealed sarcopenia alleles tiredness, falls last year, neuroticism, alcohol intake frequency, smoking, time spent watching television, higher salt, white bread, processed meat intake; whereas protective positively bone mineral density, serum testosterone, IGF1, 25-hydroxyvitamin D levels, height, intelligence, cognitive performance, educational attainment, income, physical activity, ground coffee drinking healthier diet (muesli, cereal, wholemeal or wholegrain potassium, magnesium, cheese, oily fish, protein, water, fruit, vegetable intake). Furthermore, literature data suggest single-bout resistance exercise induce changes expression 26 implicated genes m. vastus lateralis, explain beneficial strength training prevention treatment sarcopenia. In conclusion, characterized sarcopenic European-ancestry individuals from Biobank.

Language: Английский

Citations

27
Multimodal prerehabilitation for elderly patients with sarcopenia in colorectal surgery DOI Creative Commons
Jingting Wu, Hannah Chi, Shawn Kok

et al.

Annals of Coloproctology, Journal Year: 2023, Volume and Issue: 40(1), P. 3 - 12

Published: April 2, 2023

Sarcopenia, which is characterized by progressive and generalized loss of skeletal muscle mass strength, has been well described to be associated with numerous poor postoperative outcomes, such as increased perioperative mortality, sepsis, prolonged length stay, cost care, decreased functional outcome, poorer oncological outcomes in cancer surgery. Multimodal prehabilitation, a concept that involves boosting optimizing the preoperative condition patient prior upcoming stressors surgical procedure, purported benefits reversing effects sarcopenia, shortening hospitalization, improving rate return bowel activity, reducing costs quality life. This review aims present current literature surrounding its implications pertaining colorectal surgery, summary studied multimodal prehabilitation interventions, potential future advances management sarcopenia.

Language: Английский

Citations

25
Global epidemiological features and impact of osteosarcopenia: A comprehensive meta‐analysis and systematic review DOI Creative Commons
Shanping Chen,

Xiao Xu,

Huping Gong

et al.

Journal of Cachexia Sarcopenia and Muscle, Journal Year: 2023, Volume and Issue: 15(1), P. 8 - 20

Published: Dec. 12, 2023

Osteosarcopenia is defined as the concurrent occurrence of osteopenia/osteoporosis and sarcopenia. The aim current study was to perform a systematic review with meta-analysis determine global prevalence, risk factors clinical outcomes osteosarcopenia. This registered in PROSPERO (CRD42022351229). PubMed, Cochrane, Medline Embase were searched from inception February 2023 retrieve eligible observational population-based studies. Pooled osteosarcopenia prevalence calculated 95% confidence interval (CI), subgroup analyses performed. factor its association expressed odds ratio (OR) hazard (HR), respectively. Heterogeneity estimated using I

Language: Английский

Citations

24
Looking at the Data on Smoking and Post-COVID-19 Syndrome—A Literature Review DOI Open Access
Antigona Trofor,

Daniela Robu Popa,

Oana Melinte

et al.

Journal of Personalized Medicine, Journal Year: 2024, Volume and Issue: 14(1), P. 97 - 97

Published: Jan. 16, 2024

Long COVID is a recently described entity that responsible for significant morbidity and has consequences ranging from mild to life-threatening. The underlying mechanisms are not completely understood, treatment options currently limited, as existing data focus more on risk factors predictors. Smoking been reported factor poor outcomes of acute SARS-CoV-2 infection seems also play role in mediating post-COVID-19 symptoms. We aimed review relevant work addressing the interaction between smoking long order characterize smoking’s possibly identify new research directions. Methods: PubMed/MEDLINE database was searched using keywords ‘smoking’, ‘long COVID’, ‘post-acute COVID’ English-language articles published up October 2023. Results conclusions: From 374 initial hits, total 36 papers were deemed aim review. There variability concerning ways which tobacco usage quantified reported; still, there compelling evidence linking an increased developing manifestations post-acute-COVID disease. Some clinical conditions, such dyspnea, cardiovascular symptoms, cognitive or mental-health impairment, seem be relatively strongly associated with smoking, while connection upper-airway involvement less certain. available support recommending cessation tool prevention COVID.

Language: Английский

Citations

11