Effects of Exercise on Depression and Anxiety in Breast Cancer Survivors: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Cancer Medicine, Journal Year: 2025, Volume and Issue: 14(5)

Published: March 1, 2025

Numerous studies have investigated the effects of exercise on depression and anxiety in breast cancer survivors, yet results remain inconsistent. The aim this study was to investigate survivors ascertain optimal regimen for patient population. A comprehensive search conducted across Embase, PubMed, Cochrane Library, Web Science, Scopus until 28 October 2023. meta-analysis quantify standardized mean difference (SMD) 95% confidence interval (CI). total 25 met inclusion criteria. Exercise significantly alleviated (SMD, -0.63, p < 0.0001) -0.49, = 0.0002) survivors. Specifically, aerobic -0.44, 0.03) multicomponent training -0.86, 0.002) were found be particularly effective alleviating depression. However, only -0.66, 0.003) Additionally, ≥ 3 times per week (depression, SMD, -1.22, 0.006; anxiety, -0.93, 0.004) ≤ 60 min session -1.19, 0.002; -0.85, 0.005) deemed most with being intervention type. This provides clinicians evidence recommend that engage more than three week, each lasting no min, alleviate anxiety.

Language: Английский

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Differential Impact of Exercises on Quality-of-Life Improvement in Breast Cancer Survivors: A Network Meta-Analysis of Randomized Controlled Trials

Cancers, Journal Year: 2023, Volume and Issue: 15(13), P. 3380 - 3380

Published: June 28, 2023

This study aimed to assess the effectiveness of various exercise interventions in enhancing quality life for breast cancer survivors. To achieve this, randomized controlled trials were identified from major electronic databases, focusing on relationship between and The primary outcome was impact 12 weeks after intervention, with a secondary comparing dropout rates intervention groups regular care control group. protocol registered INPLASY (INPLASY202340007). A network meta-analysis nine involving 725 participants conducted, examining aerobic strength training, activity, yoga, exercise. Results showed that training most effective significantly improving survivors (1.31; 95% confidence interval: 0.49 2.12). Aerobic activity had borderline effect (0.83; 0.03 1.63), while no associated an increased risk compared group (regular care). concluded concurrent can improve survivors' without increasing care.

Language: Английский

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Lifestyle and integrative oncology interventions for cancer-related fatigue and sleep disturbances

Maturitas, Journal Year: 2024, Volume and Issue: 187, P. 108056 - 108056

Published: June 21, 2024

Fatigue, insomnia and sleep disturbances are common after cancer diagnosis, have a negative impact on quality of life function. This narrative review synthesised evidence lifestyle integrative oncology interventions for cancer-related fatigue, in survivors. There is strong support aerobic strength exercise the relief fatigue. Yoga, massage therapy, acupuncture, Tai Chi qigong can also be recommended The yoga, acupuncture therapy mixed, while appears to modest favourable effect. insufficient nutrient supplements or dietary fatigue other cancer. Beyond alleviating insomnia-related symptoms, potential effect multiple benefits, such as improvement symptoms pain menopausal symptoms. need well-designed randomised controlled trials interventions, particularly areas diet supplements, implementation studies already supported by evidence.

Language: Английский

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Prevalence and Relevance of Vitamin D Deficiency in Newly Diagnosed Breast Cancer Patients: A Pilot Study

Nutrients, Journal Year: 2023, Volume and Issue: 15(6), P. 1450 - 1450

Published: March 17, 2023

(1) Background: Vitamin D plays an important role in many types of cancer. It was the aim this study to analyze serum 25-hydroxyvitamin (25(OH)D) levels newly diagnosed breast cancer patients, and association with prognostic lifestyle factors. (2) Methods: 110 non-metastatic patients were included prospective observational “BEGYN” at Saarland University Medical Center between September 2019 January 2021. At initiation visit, 25(OH)D measured. Clinicopathological data on prognosis, nutrition, extracted from files obtained using a questionnaire. (3) Results: Median 24 ng/mL (range 5–65 ng/mL), 64.8% being vitamin deficient. higher among that reported use supplements (43 versus 22 ng/mL; p < 0.001), summer compared other seasons (p = 0.03). Patients moderate deficiency less likely have triple negative 0.047). (4) Conclusions: Routinely measured is common needs be detected treated. However, our results do not support hypothesis may main factor for

Language: Английский

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The Interplay between Microbiota and Chemotherapy-Derived Metabolites in Breast Cancer

Metabolites, Journal Year: 2023, Volume and Issue: 13(6), P. 703 - 703

Published: May 28, 2023

The most common cancer in women is breast cancer, which also the second leading cause of death this group. It is, however, important to note that some will develop or not regardless whether certain known risk factors are present. On other hand, compounds produced by bacteria gut, such as short-chain fatty acids, secondary bile and metabolites may be linked development mediate chemotherapy response. Modeling microbiota through dietary intervention identifying directly associated with its complications useful identify actionable targets improve effect antiangiogenic therapies. Metabolomics therefore a complementary approach metagenomics for purpose. As result combination both techniques, better understanding molecular biology oncogenesis can obtained. This article reviews recent literature about influence bacterial patients, well diet.

Language: Английский

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Humanistic Health Management and Cancer: Associations of Psychology, Nutrition, and Exercise with Cancer Progression and Pathogenesis

Advanced Science, Journal Year: 2024, Volume and Issue: 11(22)

Published: March 25, 2024

Abstract The incidence rate of cancer is increasing year by due to the aging population, unhealthy living, and eating habits. At present, surgery medication are still main treatments for cancer, without paying attention impact individual differences in health management on cancer. However, evidence suggests that psychological status, dietary habits, exercise frequency closely related risk prognosis reminder humanity medical concept unified treatment plan insufficient treatment, a personalized may become breakthrough point. On this basis, “Humanistic Health Management” (HHM) proposed. This healthcare focuses self‐health management, providing an accurate comprehensive evaluation lifestyle psychology, developing targeted prevention plans. review will provide detailed explanation relationship between dietary, regulatory mechanisms Intended emphasize importance HHM better prognostic efficacy, new ideas generation treatment.

Language: Английский

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Minimizing Breast Cancer Risk with Diet and Exercise

Current Breast Cancer Reports, Journal Year: 2024, Volume and Issue: 16(1), P. 45 - 52

Published: Jan. 22, 2024

Language: Английский

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Effects of Combined Interventions of Physical Activity and Diet in Childhood Cancer Survivors: A Systematic Review

Children, Journal Year: 2024, Volume and Issue: 11(7), P. 853 - 853

Published: July 13, 2024

Physical activity and diet have complementary benefits for attenuating adverse health effects that childhood cancer survivors experience after the end of treatment. This review aimed to explore impact combined physical interventions on status survivors. A thorough literature was carried out using Cochrane Library, PubMed, Scielo, LILACS Web Science databases studies published until June 2024. Studies concerning any type engaged exclusively in diet/physical were included this review. Three manuscripts met inclusion criteria. The results indicated plus showed beneficial impacts intestinal microbiome, percentage calories from sweet foods, daily consumption sugary beverages, reduction sedentary activity, mood (1 1 study each presented outcomes). Although more rigorous are needed, these findings promising regarding involving both

Language: Английский

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Impact of a Physical Exercise and Health Education Program on Metabolic Syndrome and Quality of Life in Postmenopausal Breast Cancer Women Undergoing Adjuvant Treatment with Aromatase Inhibitors

Medicina, Journal Year: 2024, Volume and Issue: 60(11), P. 1893 - 1893

Published: Nov. 18, 2024

: Adjuvant treatment with aromatase inhibitors (AIs) in breast cancer (BC) survivors can cause adverse effects such as metabolic syndrome (MS) (insulin resistance, central obesity, atherogenic dyslipidemia, and hypertension) associated morbidity premature mortality. We evaluate the effect of a multimodal program based on physical exercise health education MS health-related quality life (QoL) postmenopausal women BC under AIs.

Language: Английский

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Cancer nutritional-immunotherapy with NIR-II laser-controlled ATP release based on material repurposing strategy

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(19), P. 4629 - 4641

Published: Jan. 1, 2024

Material repurposing is proposed where the performance of carbonyl iron powder (CIP), a nutritional intervention agent supplement approved by US FDA for deficiency anemia in clinic, was explored anti-cancer treatment.

Language: Английский

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