The Gut Microbiota and Its Role in Nutraceuticals and Functional Foods DOI
Yingying Wu

Royal Society of Chemistry eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 91 - 117

Published: May 2, 2025

The human gastrointestinal (GI) tract harbours trillions of microorganisms, collectively known as gut microbiota, which have specific functions in nutrient metabolism, energy supply, xenobiotic and drug maintenance structural integrity the mucosal barrier, immunomodulation, protection against pathogens. There are direct or indirect interactions between microbiota host, constructing a complex dynamic micro-ecosystem that is closely related to nutrition health. imbalance microbial communities has been identified core defect leads number chronic diseases ranging from inflammatory metabolic conditions neurological, cardiovascular, respiratory illnesses. Extensive research studies demonstrated diet one key modulators plays an important role promotion/modulation long-term diet, well short-term macronutrient change, can rapidly reversibly alter genomic composition activities gut. However, changes distinct response different dietary components. This chapter summarises current knowledge development GI, how especially some nutraceuticals functional foods, affects health through modulation microbiota.

Language: Английский

Digestive health: functional foods for a happy gut DOI

Vaishnavi A. Pathak,

Gitanjali S. Deokar, Sanjay J. Kshirsagar

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 41 - 72

Published: Jan. 1, 2025

Language: Английский

Citations

2

Obesity, Gut Microbiota, and Metabolome: From Pathophysiology to Nutritional Interventions DOI Open Access

Zivana Puljiz,

Marko Kumrić, Josip Vrdoljak

et al.

Nutrients, Journal Year: 2023, Volume and Issue: 15(10), P. 2236 - 2236

Published: May 9, 2023

Obesity is a disorder identified by an inappropriate increase in weight relation to height and considered many international health institutions be major pandemic of the 21st century. The gut microbial ecosystem impacts obesity multiple ways that yield downstream metabolic consequences, such as affecting systemic inflammation, immune response, energy harvest, but also gut-host interface. Metabolomics, systematized study low-molecular-weight molecules take part pathways, represents serviceable method for elucidation crosstalk between hosts' metabolism microbiota. In present review, we confer about clinical preclinical studies exploring association related disorders with various microbiome profiles, effects several dietary interventions on composition metabolome. It well established nutritional may serve efficient therapeutic approach support loss obese individuals, yet no agreement exists regard most effective protocol, both short long term. However, metabolite profiling microbiota might represent opportunity methodically establish predictors control are relatively simple measure comparison traditional approaches, it tool determine optimal intervention ameliorate individual. Nevertheless, lack adequately powered randomized trials impedes application observations practice.

Language: Английский

Citations

26

Microbiota Implications in Endocrine-Related Diseases: From Development to Novel Therapeutic Approaches DOI Creative Commons
Vicente Javier Clemente‐Suárez, Laura Redondo-Flórez, Alejandro Rubio-Zarapuz

et al.

Biomedicines, Journal Year: 2024, Volume and Issue: 12(1), P. 221 - 221

Published: Jan. 18, 2024

This comprehensive review article delves into the critical role of human microbiota in development and management endocrine-related diseases. We explore complex interactions between endocrine system, emphasizing implications dysbiosis for onset progression various disorders. The aims to synthesize current knowledge, highlighting recent advancements potential novel therapeutic approaches targeting microbiota-endocrine interactions. Key topics include impact on hormone regulation, its pathologies, promising avenues modulation through diet, probiotics, prebiotics, fecal transplantation. underscore importance this research advancing personalized medicine, offering insights more tailored effective treatments

Language: Английский

Citations

15

Health Benefits of a Plant-Based Dietary Pattern and Implementation in Healthcare and Clinical Practice DOI Creative Commons
Matthew J. Landry, Catherine Ward

American Journal of Lifestyle Medicine, Journal Year: 2024, Volume and Issue: 18(5), P. 657 - 665

Published: March 14, 2024

The American College of Lifestyle Medicine recommends eating a predominantly plant-based diet with variety minimally processed vegetables, fruits, whole grains, legumes, nuts and seeds. At any level, adoption can improve one's health through mechanisms. Increasing intake foods often results in increases fiber intake, decreases saturated fat increased essential vitamins minerals, among other healthful benefits. Despite such potential benefits, many individuals are reluctant or resistant to change their usual dietary behaviors unable sustain changes over time. This is largely because an individual's decision adopt influenced by diverse array motivating factors, priorities, and/or misconceptions about nutrient adequacy diets. Here, we discuss key points from session at the Medicine's annual conference LM2023. Specifically, review common preconceptions diets, provide guidance on removing barriers adopting adhering highlight literature findings supporting benefits Last, how diets increasingly being implemented within care clinical practice support Food is/as approaches.

Language: Английский

Citations

9

Impact of the COVID-19 Pandemic on Changes in Consumer Purchasing Behavior in the Food Market with a Focus on Meat and Meat Products—A Comprehensive Literature Review DOI Creative Commons
Jagoda Żurek, M. Rudy

Foods, Journal Year: 2024, Volume and Issue: 13(6), P. 933 - 933

Published: March 19, 2024

The coronavirus has wreaked havoc on the global economy before eyes of entire world. Due to evolving consumer needs and expectations during pandemic, supply demand for various goods services varied from pre-COVID-19 period. This article aims understand changes in purchasing food choices, focusing particularly meat products, made by consumers households response crisis caused COVID-19 pandemic. study also indicates impact directions these assesses magnitude contribution determinants that influenced them. literature review 2020 2023 was conducted using Scopus Web Science scientific databases. identified sociodemographic individual factors as main influencing consumers' or eating behavior. Positive shifts (e.g., implementing strategies better manage at home through activities like creating shopping lists, average increase spending store visits, decrease visit frequencies) negative shortages products stores due panic buying, unusually high resulting stockpiling, fewer fresh increased consumption unhealthy foods snacking, among other factors) isolation were motivation, mental state) gender, age, income level, education). While had a greater behavior early stages socio-demographic became more important pandemic progressed.

Language: Английский

Citations

8

The Effect of Dietary Types on Gut Microbiota Composition and Development of Non-Communicable Diseases: A Narrative Review DOI Open Access

Martin Soldán,

Ľubica Argalášová,

Lucia Hadvinová

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(18), P. 3134 - 3134

Published: Sept. 17, 2024

Introduction: The importance of diet in shaping the gut microbiota is well established and may help improve an individual’s overall health. Many other factors, such as genetics, age, exercise, antibiotic therapy, or tobacco use, also play a role influencing microbiota. Aim: This narrative review summarizes how three distinct dietary types (plant-based, Mediterranean, Western) affect composition development non-communicable diseases (NCDs). Methods: A comprehensive literature search was conducted using PubMed, Web Science, Scopus databases, focusing on keywords “dietary pattern”, “gut microbiota” “dysbiosis”. Results: Both plant-based Mediterranean diets have been shown to promote production beneficial bacterial metabolites, short-chain fatty acids (SCFAs), while simultaneously lowering concentrations trimethylamine-N-oxide (TMAO), molecule associated with negative health outcomes. Additionally, they positive impact microbial diversity therefore are generally considered healthy types. On hand, Western typical example unhealthy nutritional approach leading overgrowth pathogenic bacteria, where TMAO levels rise SCFA drops due dysbiosis. Conclusion: current scientific consistently highlights superiority over promoting preventing NCDs. Understanding influence modulation pave way for novel therapeutic strategies.

Language: Английский

Citations

8

Effects of Plant-Based Diet on Metabolic Parameters, Liver and Kidney Steatosis: A Prospective Interventional Open-label Study DOI Open Access
Begüm Güler Şentürk, Bengı Gürses,

Ceren Soyturk

et al.

British Journal Of Nutrition, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 22

Published: Jan. 10, 2025

Abstract This interventional single-center prospective open-label study aims to evaluate the effects of a vegan diet, compared vegetarian and omnivorous on metabolic parameters, insulin sensitivity, liver kidney steatosis in healthy adults. The included 53 participants aged 18-40 years, body-mass index 18-30 kg/m2, without any chronic disease, medication use, active smoking, or significant alcohol consumption. All were at baseline selected continue an diet transition with follow-up over six months. Anthropometric measurements, biochemical assessed after months using magnetic resonance imaging-proton density fat fraction (MRI-PDFF). Primary outcomes changes steatosis, while secondary alterations anthropometric markers. Among participants, 18 followed 21 adopted 14 transitioned diet. Dietary interventions did not result statistically body mass index, mass, percentage, muscle However, improvements systolic diastolic blood pressure, favoring observed. We aimed control for potentially confounding variables ensure reliability these findings. have demonstrated better decline lower pole, total hilus Liver 6 vegans. that plant-based is associated several parameters may reduce steatosis.

Language: Английский

Citations

1

Vegan diet: nutritional components, implementation, and effects on adults’ health DOI Creative Commons
Edyta Łuszczki,

Faustina Boakye,

Magdalena Zielińska

et al.

Frontiers in Nutrition, Journal Year: 2023, Volume and Issue: 10

Published: Nov. 9, 2023

Vegan diet has emerged as a popular dietary choice for people worldwide in recent times, due to concerns such health issues, animal rights and welfare, the sustainability of environment. The purpose this literature review was explain how vegan may affect adults point out beneficial components found it well any difficulties associated with its implementation. Evidence supports that can reduce risk chronic diseases, type 2 diabetes, hypertension, certain types cancer. A well-planned must include adequate calories nutrients, necessary supplements, vitamin B12, D EPA/DHA. Given current growing interest plant-based diets among general population, is crucial understand both barriers, risks, benefits physicians, policy makers, population.

Language: Английский

Citations

22

Unveiling the dynamics of gut microbial interactions: a review of dietary impact and precision nutrition in gastrointestinal health DOI Creative Commons
Zifang Shang,

Liu Pai,

Sandip Patil

et al.

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: May 30, 2024

The human microbiome, a dynamic ecosystem within the gastrointestinal tract, plays pivotal role in shaping overall health. This review delves into six interconnected sections, unraveling intricate relationship between diet, gut microbiota, and their profound impact on dance of nutrients orchestrates complex symphony, influencing digestive processes susceptibility to disorders. Emphasizing bidirectional communication brain, Brain-Gut Axis section highlights crucial dietary choices physical, mental, emotional well-being. Autoimmune diseases, particularly those manifesting reveal delicate balance disrupted by microbiome imbalances. Strategies for reconciling microbes through diets, precision nutrition, clinical indications showcase promising avenues managing distress revolutionizing healthcare. From Low-FODMAP diet neuro-gut interventions, these strategies provide holistic understanding gut’s world. Precision as groundbreaking discipline, holds transformative potential tailoring recommendations individual microbiota compositions, reshaping landscape Recent advancements indications, including exact probiotics, fecal transplantation, signify new era where actively participates therapeutic strategies. As takes center stage healthcare, paradigm shift toward personalized effective treatments disorders emerges, reflecting symbiotic body its microbial companions.

Language: Английский

Citations

8

Foodomics-based metabolites profiling of the Greek yogurt incorporated with unripened papaya peel powder DOI Creative Commons

Sohan Lal Bajya,

Durga Shankar Bunkar,

Surbhi Goyal

et al.

Food Chemistry Molecular Sciences, Journal Year: 2024, Volume and Issue: 8, P. 100199 - 100199

Published: March 11, 2024

The food waste of the fruit processing industry is rich in many bio-active components such as polysaccharides, polyphenols, peptides, etc. that own multifaceted health benefits. valorization this an intriguing optimization method for various dairy products. Meanwhile, LC-MS-based foodomics has been emerging approach quantitative and qualitative analysis foods. Untargeted metabolomics done optimized functional yogurt contains different levels unripened papaya peel powder (UPPP) using high-resolution mass spectroscopy added matrix. UPPP comprises a high content phytochemicals which could give functionality therapeutic effect to Greek yogurt. A total 36 metabolites have identified health-beneficial attributes. Kaempferol, ostruthin, putative carpaine derivatives, are some importance with wide area coverage metabolome. This work highlights bioactivity its prebiotic properties independent ingredient. incorporated plant-based ingredients like can effectively enhance attributes yogurt, potential synbiotic food.

Language: Английский

Citations

6