Cureus,
Journal Year:
2023,
Volume and Issue:
unknown
Published: Sept. 25, 2023
As
many
prior
case
reports
have
shown,
unregulated
supplements
and
alcohol
are
both
known
to
cause
varying
degrees
of
hepatotoxicity.
We
present
a
47-year-old
male
who
presented
the
hospital
with
headache
abdominal
pain
after
consuming
Reishi
Mushroom
(Ganoderma
lingzhi)
powder
alcohol.
The
patient
was
found
acute
hepatitis
significant
transaminitis,
which
managed
conservatively
N-acetylcysteine
IV
fluids.
Two-week
follow-up
labs
demonstrated
complete
resolution
patient's
symptoms
laboratory
abnormalities.
Despite
growing
popularity
mushroom-based
supplements,
limited
research
has
been
done
on
systemic
effects
that
can
manifest
co-ingestion
other
substances
such
as
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(7), P. e29128 - e29128
Published: April 1, 2024
Pesticides
are
chemical
constituents
used
to
prevent
or
control
pests,
including
insects,
rodents,
fungi,
weeds,
and
other
unwanted
organisms.
Despite
their
advantages
in
crop
production
disease
management,
the
use
of
pesticides
poses
significant
hazards
environment
public
health.
Pesticide
elements
have
now
perpetually
entered
our
atmosphere
subsequently
contaminated
water,
food,
soil,
leading
health
threats
ranging
from
acute
chronic
toxicities.
can
cause
toxicity
if
a
high
dose
is
inhaled,
ingested,
comes
into
contact
with
skin
eyes,
while
prolonged
recurrent
exposure
leads
toxicity.
produce
different
types
toxicity,
for
instance,
neurotoxicity,
mutagenicity,
carcinogenicity,
teratogenicity,
endocrine
disruption.
The
pesticide
formulation
may
depend
on
specific
active
ingredient
presence
synergistic
inert
compounds
that
enhance
modify
its
Safety
concerns
need
hour
contemporary
pesticide-induced
hazards.
effectiveness
implementation
current
legislature
providing
ample
protection
human
key
concerns.
This
review
explored
comprehensive
summary
regarding
updated
impacts
advanced
safety
legislation.
Implementing
regulations,
proper
training,
education
help
mitigate
negative
promote
safer
more
sustainable
agricultural
practices.
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(3), P. e25607 - e25607
Published: Feb. 1, 2024
Ganoderma
lucidum
is
a
versatile
mushroom.
Polysaccharides
and
triterpenoids
are
the
major
bioactive
compounds
have
been
used
as
traditional
medicinal
mushrooms
since
ancient
times.
They
currently
nutraceuticals
functional
foods.
G.
extracts
their
an
alternative
to
antioxidants
antimicrobial
agents.
Secondary
metabolites
with
many
properties
make
it
possible
substitute
that
could
be
applied
immunomodulatory,
anticancer,
antimicrobial,
anti-oxidant,
anti-inflammatory,
anti-diabetic.
The
miraculous
of
secondary
fascinate
researchers
for
development
production.
Recent
studies
paid
close
attention
different
physical,
genetic,
biochemical,
nutritional
parameters
potentiate
production
metabolites.
This
review
effort
collect
biologically
active
constituents
from
reveal
potential
actions
against
diseases
latest
improvement
in
novel
technique
get
maximum
Studies
going
ahead
determine
efficacy
numerous
assess
valuable
achieved
by
favor
antioxidant
outcomes.
New Zealand Journal of Botany,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 85
Published: July 22, 2024
Ganoderma,
a
genus
of
mushrooms
known
for
its
long
history
medicinal
use,
has
gained
increasing
attention
in
recent
years
due
to
potential
health
benefits.
This
review
delves
into
the
bioactive
compounds
found
Ganoderma
and
elucidates
intricate
mechanisms
underlying
immunomodulatory
anti-tumour
activities.
The
diverse
health-promoting
effects
can
be
attributed
decadent
array
compounds,
notably
polysaccharides,
triterpenoids,
which
play
pivotal
role.
ability
mushroom
modulate
immune
system,
enhancing
activity
cells,
such
as
natural
killer
cells
macrophages,
is
central
focus.
Furthermore,
we
explore
how
exerts
through
induction
apoptosis,
inhibition
angiogenesis,
interference
with
various
signalling
pathways
critical
cancer
cell
growth
metastasis.
As
research
this
area
continues
evolve,
comprehensive
understanding
supplement
role
promoting
well-being
emerging,
offering
promising
avenues
further
investigation
application
healthcare.
Frontiers in Microbiology,
Journal Year:
2024,
Volume and Issue:
15
Published: March 18, 2024
Driven
by
the
good
developmental
potential
and
favorable
environment
at
this
stage,
Ganoderma
lucidum
is
recognized
as
a
precious
large
fungus
with
medicinal
nutritional
health
care
values.
Among
them,
polysaccharides,
triterpenoids,
oligosaccharides,
trace
elements,
etc.
are
important
bioactive
components
in
G.
.
These
will
have
an
impact
on
gut
flora,
thus
alleviating
diseases
such
hyperglycemia,
hyperlipidemia
obesity
caused
flora
disorder.
While
numerous
studies
demonstrated
ability
of
its
active
to
regulate
systematic
review
mechanism
currently
lacking.
The
purpose
paper
summarize
regulatory
effects
cardiovascular,
gastrointestinal
renal
metabolic
diseases,
research
progress
improving
related
regulating
flora.
Additionally,
delves
into
principle
which
can
treat
or
assist
intestinal
tract
medicine,
food
clinical
application
were
fully
explored
for
researchers.
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(19), P. e36987 - e36987
Published: Aug. 29, 2024
(GL)
is
a
potent
source
of
bioactive
compounds
with
diverse
nutritional
and
pharmacological
benefits.
Its
popularity
as
dietary
supplement,
herbal
remedy,
wellness
product
steadily
on
the
rise.
Furthermore,
standardized
advancement
GL
industry
has
facilitated
reliable
sourcing
raw
materials
quality
control
measures,
enhancing
its
utilization
endorsement
in
realms
science
pharmaceutical
research.
This
article
provides
comprehensive
overview
recent
advancements
research
pertaining
to
components
GL,
particularly
polysaccharides
(GLP)
triterpenes
(GLTs)
well
highlights
latest
findings
regarding
their
beneficial
effects
human
diseases,
including
anticancer,
antidiabetes,
liver
protection
other
aspects
(such
regulating
gut
microbiota,
antioxidant,
antimicrobial,
antiinflammatory
immune
regulation).
we
summarized
potential
applications
food
sectors,
while
also
examining
current
status
standardization
throughout
entire
industrial
chain
both
domestically
internationally.
These
information
offer
an
insight
guidance
for
prospects
development
innovative
within
global
health
industry.
New
techniques
for
extracting
and
screening
xanthine
oxidase
(XOD)
inhibitors
from
Changbaishan
ganoderma
have
been
developed
to
enhance
the
efficiency
of
medicinal
fungi
preparation.
In
order
determine
accuracy
in
vitro
XOD
inhibitor
screening,
we
used
AUF-LC-MS
method
screen
characterize
active
substances.
Subsequently,
antigout
activity
ingredients
was
tested
using
molecular
docking
kinetics.
To
improve
extraction
isolation
bioactive
substances
ganoderma,
a
comprehensive
activity-oriented
preparation
that
integrates
BP
neural
networks,
response
surface
methodology
extraction,
UNIFAC/DMD
countercurrent
chromatography
efficiently
extract
isolate
identified
inhibitors.
Additionally,
enzyme
kinetics
analysis
conducted
elucidate
their
interactions
with
XOD,
IC50
values
Ganoderic
acid
I,
Lucidone
A,
C2
Lucidenic
A
were
determined
be
16.48,
19.48,
18.36,
24.14,
19.78
mg/mL,
respectively.
Finally,
network
pharmacology
elucidated
anti-gout
five
compounds,
mechanisms
action
discussed.
This
study
reveals
compounds
potential
treating
gout,
offering
insights
developing
functional
foods
renewable
energy.
