Designing Nutrition for Health—Incorporating Dietary By-Products into Poultry Feeds to Create Functional Foods with Insights into Health Benefits, Risks, Bioactive Compounds, Food Component Functionality and Safety Regulations

Foods, Journal Year: 2023, Volume and Issue: 12(21), P. 4001 - 4001

Published: Nov. 1, 2023

This review delves into the concept of nutrition by design, exploring relationship between poultry production, utilization dietary by-products to create functional foods, and their impact on human health. Functional foods are defined as products that extend beyond basic nutritional value, offering potential benefits in disease prevention management. Various methods, including extraction, fermentation, enrichment, biotechnology, nanotechnology, employed obtain bioactive compounds for these foods. also examines innovative approach enhancing livestock diets through animal-based methods. Bioactive found such essential fatty acids, antioxidants, carotenoids, minerals, vitamins, peptides, highlighted promoting well-being mitigating chronic diseases. Additionally, explores functionality food components within products, emphasizing critical roles bioaccessibility, bioactivity, bioavailability The importance considering key aspects design enhanced production is thoroughly reviewed. safety establishment regulations guidelines was It concluded integration principles empowers individuals make informed choices can prioritize health well-being. By incorporating rich compounds, consumers proactively take steps prevent manage issues, ultimately contributing a healthier society lifestyle.

Language: Английский

---

Sesame Seeds: A Nutrient-Rich Superfood

Foods, Journal Year: 2024, Volume and Issue: 13(8), P. 1153 - 1153

Published: April 10, 2024

Sesame seeds (

---

Recent Developments in Nanoparticle Formulations for Resveratrol Encapsulation as an Anticancer Agent

Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(1), P. 126 - 126

Published: Jan. 18, 2024

Resveratrol is a polyphenolic compound that has gained considerable attention in the past decade due to its multifaceted therapeutic potential, including anti-inflammatory and anticancer properties. However, efficacy impeded by low water solubility, dose-limiting toxicity, bioavailability, rapid hepatic metabolism. To overcome these hurdles, various nanoparticles such as organic inorganic nanoparticles, liposomes, polymeric dendrimers, solid lipid gold zinc oxide zeolitic imidazolate frameworks, carbon nanotubes, bioactive glass mesoporous were employed deliver resveratrol, enhancing against types of cancer. Resveratrol-loaded nanoparticle or resveratrol-conjugated administration exhibits excellent potency compared free resveratrol. This review highlights latest developments nanoparticle-based delivery systems for focusing on potential limitations associated with compound’s bioavailability effectiveness.

Language: Английский

---

Bee Pollen Phytochemicals and Nutrients as Unequaled Pool of Epigenetic Regulators: Implications for Age-Related Diseases

Foods, Journal Year: 2025, Volume and Issue: 14(3), P. 347 - 347

Published: Jan. 21, 2025

Bee pollen is characterized by an exceptional diversity and abundance of micronutrients bioactive phytochemicals. This richness remains very sparsely investigated, but accumulating evidence strongly supports a promising future for bee in human nutrition medicine. Epigenetic regulation among the most compelling biomedical topics that remain completely untapped derivative research. In our current research, we identified numerous ubiquitous compounds are consistently present this matrix, regardless its botanical geographical origins, have been well studied documented as epigenetic regulators recent years. Given relative newness both research studies within nutritional, pharmaceutical, medical sciences, review aims to bridge these valuable fields advance related experimental investigations. To best knowledge, first work has aimed comprehensively investigate modulatory potential compounds. Our findings also unveiled several intriguing phenomena, such dual effect same compound depending on cellular context or some cross-generational heritability traits. Although whole extract still lacking, study clearly indicates avenue worth further We hope constitutes foundational cornerstone investigations

Language: Английский

---

Recent Progress in Nanotechnology Improving the Therapeutic Potential of Polyphenols for Cancer

Nutrients, Journal Year: 2023, Volume and Issue: 15(14), P. 3136 - 3136

Published: July 13, 2023

Polyphenols derived from fruits, vegetables, and plants are bioactive compounds potentially beneficial to human health. Notably, such as quercetin, curcumin, epigallocatechin-3-gallate (EGCG), resveratrol have been highlighted antiproliferative agents for cancer. Due their low solubility limited bioavailability, some alternative nanotechnologies applied encapsulate these compounds, aiming improve efficacy against In this comprehensive review, we evaluate the main nanotechnology approaches therapeutic potential of polyphenols cancer using in vitro studies vivo preclinical models, highlighting recent advancements field. It was found that polymeric nanomaterials, lipid-based inorganic carbon-based nanomaterials most used classes nanocarriers encapsulating polyphenols. These delivery systems exhibit enhanced antitumor activity pro-apoptotic effects, particularly breast, lung, prostate, cervical, colorectal cells, surpassing performance free compounds. Preclinical trials xenograft animal models revealed decreased tumor growth after treatment with polyphenol-loaded systems. Moreover, interaction polyphenol co-delivery polyphenol–drug is a promising approach increase anticancer decrease chemotherapy side effects. innovative hold significant implications advancement clinical research.

Language: Английский

---

Anticancer Potential of Flavonoids: An Overview with an Emphasis on Tangeretin

Pharmaceuticals, Journal Year: 2023, Volume and Issue: 16(9), P. 1229 - 1229

Published: Aug. 30, 2023

Natural compounds with pharmacological activity, flavonoids have been the subject of an exponential increase in studies field scientific research focused on therapeutic purposes due to their bioactive properties, such as antioxidant, anti-inflammatory, anti-aging, antibacterial, antiviral, neuroprotective, radioprotective, and antitumor activities. The biological potential flavonoids, added bioavailability, cost-effectiveness, minimal side effects, direct them promising cytotoxic anticancer optimization therapies search for new drugs treatment cancer, since some extensively antineoplastic approaches become less effective tumor resistance commonly used chemotherapy. In this review, we emphasize properties tangeretin, a flavonoid found citrus fruits that has shown activity against hallmarks cancer several types cancerous cell lines, antiproliferative, apoptotic, anti-metastatic, anti-angiogenic, regulatory expression tumor-suppressor genes, epigenetic modulation.

Language: Английский

---

Bioactivity and Bioavailability of Carotenoids Applied in Human Health: Technological Advances and Innovation

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(14), P. 7603 - 7603

Published: July 11, 2024

This article presents a groundbreaking perspective on carotenoids, focusing their innovative applications and transformative potential in human health medicine. Research jointly delves deeper into the bioactivity bioavailability of revealing therapeutic uses technological advances that have to revolutionize medical treatments. We explore pioneering which carotenoids are used treat chronic diseases such as cancer, cardiovascular disease, age-related macular degeneration, offering novel protective mechanisms benefits. Our study also shows cutting-edge innovations carotenoid extraction bioavailability, including development supramolecular carriers advanced nanotechnology, dramatically improve absorption efficacy these compounds. These not only ensure consistent quality but tailor therapies each patient's needs, paving way for personalized By integrating latest scientific discoveries techniques, this research provides prospective clinical establishing new benchmark future studies field. findings underscore importance optimizing extraction, administration, bioactivity, methods develop more effective, targeted, treatments, thus visionary insight modern practices.

Language: Английский

---

Exploring the phytochemical profile, antioxidant activity, and anticancer potential of Achillea millefolium extracts: In-vitro and in-silico investigation

South African Journal of Botany, Journal Year: 2025, Volume and Issue: 177, P. 684 - 698

Published: Jan. 9, 2025

Language: Английский

---

The Use of Herbal Medicine for Cancer Therapy in Indonesia: A Prospective Cohort Study

Journal of Herbal Medicine, Journal Year: 2025, Volume and Issue: unknown, P. 100991 - 100991

Published: Feb. 1, 2025

Language: Английский

---

Supplement Use and Increased Risks of Cancer: Unveiling the Other Side of the Coin

Cancers, Journal Year: 2024, Volume and Issue: 16(5), P. 880 - 880

Published: Feb. 22, 2024

There is a rising trend in the consumption of dietary supplements, especially among adults, with purpose improving health. While marketing campaigns tout potential health benefits using it critical to evaluate harmful effects associated these supplements as well. The majority scarce research on vitamins focuses acute or chronic toxicities use supplements. Quality still required further investigate risks long-term risk developing cancers. present review concentrates studies that have investigated association between cancers and mortality Such an has been reported for several vitamins, minerals, other Even though come their own shortcomings critics, they must draw attention adverse advise consumers healthcare providers ponder extensive

Language: Английский

---