From theory to practice: challenges and rewards of implementing ketogenic metabolic therapy in mental health

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: Feb. 8, 2024

This perspective article delves into the implementation of Ketogenic Metabolic Therapy (KMT) by a mental health counselor who attempts to bridge gap between emerging research and real-world clinical application. Grounded in author’s experiences, communicates potential KMT care, highlighting both its therapeutic promise insights gained from hands-on patient interactions. While adoption necessitates adjustments societal, emotional, dietary domains, especially within diverse contexts, these challenges are surmountable with appropriate guidance support. The encourages capture qualitative data alongside quantitative measures advocates for an approach that considers broader implications improved well-being on families communities. As field advances, interdisciplinary collaborations researchers clinicians will be pivotal refining expanding application KMT, ultimately enhancing outcomes elevating standard care.

Language: Английский

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The Effects of Ketogenic Diet on Brain Gene Expressions in Type 2 Diabetes Background

Neuroscience, Journal Year: 2024, Volume and Issue: 549, P. 101 - 109

Published: May 10, 2024

Language: Английский

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Bringing nutritional ketosis to the table as an option for healing the pediatric brain

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: June 12, 2024

Our core premise is that personalized variations of a ketogenic diet are likely to benefit pediatric patients with neuropsychiatric symptoms across multiple domains. Although epilepsy currently well-accepted indication for strict diet, there dearth knowledge and therefore clinical guidelines upon which recommend nutritional ketosis pervasive conditions such as autism spectrum disorder ADHD, even when comorbid present. However, published cohort studies current trials implementing medical therapies cognitive impairment, psychiatric comorbidities, motor disability, neuroinflammation. As holistic practitioners, it imperative we consider the health child in its entirety - additionally offer therapeutic option may be synergistic treating extra-neurologic diseases obesity. While uniquely potential adverse side effects linear growth deceleration micronutrient deficiencies, previous our center’s experience have already proven low-risk intervention optimized appropriate patient monitoring support.

Language: Английский

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Ketogenic diet as a therapeutic approach in autism spectrum disorder: a narrative review

Metabolic Brain Disease, Journal Year: 2024, Volume and Issue: 40(1)

Published: Dec. 18, 2024

Language: Английский

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Impact of psychiatric comorbidities on the treatment of epilepsies in adults

Expert Review of Neurotherapeutics, Journal Year: 2023, Volume and Issue: 23(10), P. 895 - 904

Published: Sept. 6, 2023

Epilepsy is often accompanied by psychiatric comorbidities and the management of epilepsy in these patients presents unique challenges due to interplay between underlying neurological condition symptoms combined use multiple medications.This paper aims explore complexities associated with managing presence comorbidities, focusing on impact disorders treatment strategies posed simultaneous administration medications.Patients seem present a more severe form that resistant drug treatments burdened an increased morbidity mortality. Whether prompt can influence long-term prognosis still unclear as well role specific strategies, such neuromodulation, this group patients. Clinical practice recommendations guidelines will development new models integrated care be implemented.

Language: Английский

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CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction

Aging, Journal Year: 2024, Volume and Issue: 16(6), P. 4980 - 4999

Published: March 20, 2024

Background: Modulated by differences in genetic and environmental factors, laboratory mice often show progressive weight gain, eventually leading to obesity metabolic dyshomeostasis. Since the geroneuroprotector CMS121 has a positive effect on energy metabolism mouse model of type 2 diabetes, we investigated potential counteract changes observed during ageing process wild mice. Methods: Control or CMS121-containing diets were supplied ad libitum for 6 months, sacrificed at age 7 months. Blood, adipose tissue, liver analyzed glucose, lipids, protein markers metabolism. Results: The diet induced 40% decrease body gain improved both glucose lipid indexes. Lower levels hepatic caspase 1, 3, NOX4 with indicating lower inflammatory status. Adipose tissue from CMS121-treated showed increased transcription factors Nrf1 TFAM, as well mitochondrial electron transport complexes, GLUT4 higher resting rate. Metabolomic analysis revealed elevated plasma concentrations short chain acylcarnitines butyrate metabolites treated CMS121. Conclusions: diminished de novo lipogenesis, which is associated acetyl-CoA, acylcarnitine, metabolite levels, could contribute safeguarding not only peripheral system but also aging brain. By mimicking effects ketogenic diets, holds promise diseases such since these are hard follow over long term.

Language: Английский

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Alterations to the Copulatory Sequence in Young Adult Male Sprague-Dawley Rats Administered a Ketogenic Diet

Published: Jan. 1, 2024

Ketogenic diets (KDs) have shown therapeutic potential for a range of neuropsychiatric disorders; however, there is insufficient data regarding the behavioral impacts KDs in healthy populations. Here, we examined impact KD on sexual behavior young adult male Sprague-Dawley rats maintained either or standard chow diet (SD). We found that males exhibited more mounts (across all four sex tests), intromissions (third and fourth tests) lower ejaculation likelihood (second test) compared to SD males. These results suggest reduced reinforcing properties contact necessary achieve

Language: Английский

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Alterations to the copulatory sequence in young adult male Sprague-Dawley rats administered a ketogenic diet

Physiology & Behavior, Journal Year: 2024, Volume and Issue: 285, P. 114650 - 114650

Published: July 27, 2024

Language: Английский

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Ketogenic diets in clinical psychology: examining the evidence and implications for practice

Frontiers in Psychology, Journal Year: 2024, Volume and Issue: 15

Published: Sept. 26, 2024

Introduction The application of ketogenic dietary interventions to mental health treatments is increasingly acknowledged within medical and psychiatric fields, yet its exploration in clinical psychology remains limited. This article discusses the potential implications diets, traditionally utilized for neurological disorders, broader practices. Methods presents a perspective based on existing diet research historical use, biological mechanisms, therapeutic benefits. It examines these diets treatment their relevance practice. Results review informs psychologists benefits introduces literature underlying mechanisms involved, such as modulation neurotransmitters, reduction inflammation, stabilization brain energy metabolism, demonstrating biopsychosocial practice psychology. Conclusion By considering metabolic therapies, can broaden scope integration provides care model that incorporates knowledge option care. emphasizes need further training support effective implementation this psychiatry intervention.

Language: Английский

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Multiple sclerosis and ketogenic diets

British Journal of Neuroscience Nursing, Journal Year: 2023, Volume and Issue: 19(Sup4), P. S30 - S31

Published: July 2, 2023

George Winter discusses the extent to which an anti-inflammatory ketogenic diet can influence progress of a chronic autoimmune and/or inflammatory disease, such as multiple sclerosis.

Language: Английский

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