A review of ten (10) edible plants in Nigeria as promising repositories of anticancer bioactivity: Implications for medical nutrition therapy DOI

Adeoye Bayo Olufunso,

Oyerinde Ayodeji Michael,

Oyedayo Phillips Akano

et al.

Journal of Pharmacy and Allied Medicine, Journal Year: 2024, Volume and Issue: 2(1), P. 26 - 39

Published: Jan. 1, 2024

Language: Английский

Antioxidant, Anti-Inflammatory, Antimicrobial, and Anticancer Activities of Pomegranate Juice Concentrate DOI Open Access
Hosam M. Habib, Hamada El‐Gendi, Esmail M. El‐Fakharany

et al.

Nutrients, Journal Year: 2023, Volume and Issue: 15(12), P. 2709 - 2709

Published: June 11, 2023

Pomegranate juice concentrate (PJC) is a rich source of polyphenols, which exhibit significant antioxidant activity and potential health benefits for disease prevention therapy. In this study, the polyphenolic profile PJC was investigated first time, it found that can inhibit oxidative damage to bovine serum albumin (BSA) deoxyribonucleic acid (DNA), as well acetylcholinesterase, α-amylase, tyrosinase activities. The primary polyphenols identified in were 4-Hydroxy-3-Methoxybenzoate, epicatechin, catechin, rutin, ferulic acid, P-coumaric cinnamic acid. Additionally, demonstrated potent antibacterial effects against human pathogens such Streptococcus mutans Aeromonas hydrophila dose-dependently reduced proliferation colorectal, breast, hepatic cancer cells via apoptosis. Furthermore, blocked B-cell lymphoma 2 (BCl-2) expression cyclin-dependent kinase inhibitor (P21) enhanced tumor protein (P53) expression, compared both untreated treated with fluoropyrimidine 5-fluorouracil (5-FU). As result, may be beneficial ingredient formulation emerging natural-compound-based chemotherapy functional foods could utilized by food, nutraceutical, pharmaceutical industries.

Language: Английский

Citations

24
Optimizing Physicochemical Properties, Antioxidant Potential, and Antibacterial Activity of Dry Ginger Extract Using Sonication Treatment DOI Creative Commons
Nashi K. Alqahtani, Zakaria A. Salih, Saeed A. Asiri

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(16), P. e36473 - e36473

Published: Aug. 1, 2024

This research paper focused on enhancing the physico-chemical attributes, antioxidant capacity, and antibacterial effectiveness of dry ginger extract through sonication as an assistant extraction treatment. Ginger, resulting from rhizome

Language: Английский

Citations

7
Rutin Isolated from Acalypha indica L.: A Comprehensive Analysis of Its Antibacterial and Anticancer Activities DOI

Sudhakar Chekuri,

Sanjeeva Reddy Sirigiripeta,

Sreenu Thupakula

et al.

Biochemical and Biophysical Research Communications, Journal Year: 2025, Volume and Issue: 765, P. 151833 - 151833

Published: April 16, 2025

Language: Английский

Citations

0
Machine learning insights into the antioxidant and biomolecular shielding effects of polyphenol-rich 18 date palm pit extracts DOI Creative Commons
Nashi K. Alqahtani, Tareq M. Alnemr,

Hoda A. S. Farag

et al.

Food Chemistry X, Journal Year: 2025, Volume and Issue: 27, P. 102480 - 102480

Published: April 1, 2025

Language: Английский

Citations

0
Bioactive compounds and nutritional composition of butternut pumpkins (Cucurbita moschata) cultivated in Saudi Arabia (Hassawi Popper) DOI Creative Commons
Nashi K. Alqahtani

Journal of Future Foods, Journal Year: 2025, Volume and Issue: unknown

Published: May 1, 2025

Language: Английский

Citations

0
Facile phyto-mediated synthesis of ternary CuO/Mn3O4/ZnO nanocomposite using Nigella Sativa seeds extract: characterization,antimicrobial, and biomedical evaluations DOI Creative Commons
Shahira H. EL‐Moslamy, Yousra A. El‐Maradny, Mohamed H. El‐Sayed

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: May 8, 2025

The phyto-synthesis of ternary CuO/ Mn3O4/ZnO nanocomposite was achieved by the utilization an eco-friendly, straightforward approach that involved extract Nigella sativa seeds. Our appears to include equal amounts CuO, Mn3O4, and ZnO based on atomic percentages. results indicate a robust thermally stable CuO/Mn3O4/ZnO developed in nanosuspensions. nanocomposites showed antimicrobial capabilities against multidrug-resistant human pathogens. highest biofilm reduction viable planktonic populations all pathogens investigated significantly reduced with value 18.5 µg/mL. unique, enhanced, triple-combined properties enabled have strong ability. exhibited anticancer activity A549, MDA, HCT-116, HepG2 cells, selectivity index values ​​ranging from 24.72 41.96. appeared induce selective dose-dependent nuclear condensation cell shrinkage treated cancer inducing apoptosis mechanism combat progression. phytosynthetic triggering apoptotic mechanisms This pathway confirmed affinity for ErbBs VEGF potent antioxidant scavenge ABTS DPPH radicals at EC50 ​​of 236.6 µg/mL 134.8 µg/mL, respectively.

Language: Английский

Citations

0
Fabrication of α-lactalbumin-coated chamomile nano-emulsion for their synergistic anticancer and anti-inflammatory applications DOI
Ali G. Alkhathami,

Mahmoud Ashry,

Omkulthom Al Kamaly

et al.

Medical Oncology, Journal Year: 2025, Volume and Issue: 42(6)

Published: May 12, 2025

Language: Английский

Citations

0
Machine Learning Prediction of 18 Date Palm Polyphenol Protection Against Biomolecular Damage DOI Creative Commons
Nashi K. Alqahtani, Tareq M. Alnemr, Rania Ismail

et al.

Journal of Agriculture and Food Research, Journal Year: 2025, Volume and Issue: unknown, P. 102019 - 102019

Published: May 1, 2025

Language: Английский

Citations

0
Phoenix dactylifera L.: An Overview of Phytochemical Constituents and Impact on Women's Health DOI
Enaam M. AbouZeid, Ahmed H. Afifi, Rehab A. Hussein

et al.

Chemistry & Biodiversity, Journal Year: 2024, Volume and Issue: 21(7)

Published: April 30, 2024

Phoenix dactylifera L. (date palm) is the most significant member of palm family (Arecaceae), particularly in Middle East and Arab World. It a valuable source both primary secondary metabolites including sugars, amino acids, phenolic flavonoids, proanthocyanidins, carotenoids, phytosterols, terpenes sphingolipids, besides vitamins minerals. Besides, it possesses wide array pharmacologic activities viz. immunomodulatory, antioxidant, anti-inflammatory, hepatoprotective, nephroprotective, anti-mutagenic anti-cancer activities, addition to its positive effects on male female fertility. Further research still required deeply understand clinical implications, especially concerning women's health. Moreover, there are other species that need be investigated learn more about their undiscovered phytochemical components biological activities.

Language: Английский

Citations

3
Moringa oleifera seed methanol extract with consolidated antimicrobial, antioxidant, anti‐inflammatory, and anticancer activities DOI
Esmail M. El‐Fakharany, Wafaa B. Elsharkawy, Yousra A. El‐Maradny

et al.

Journal of Food Science, Journal Year: 2024, Volume and Issue: 89(8), P. 5130 - 5149

Published: July 2, 2024

The wide biological activity of the Moringa oleifera represents a potential opportunity for developing selective cancer treatment drugs. bioactive phytochemicals in seed extract (MSE) indicated large numbers (21 compounds) with dominant abundance cycloisolongifolene, 8,9-dehydro-9-vinyl, and chamazulene accounting 12.7% 12.19% total detected compounds. MSE showed potent anticancer effect toward Caco-2, MDA, HepG-2 cells half-maximal inhibitory concentration (IC

Language: Английский

Citations

3