Comprehensive Lipidomics Analysis of Cape Hake (Merluccius capensis) By-Products: Screening Key Features for Added Value Applications
Applied Food Research,
Journal Year:
2025,
Volume and Issue:
unknown, P. 100839 - 100839
Published: March 1, 2025
Language: Английский
Impact of a Mediterranean-Inspired Diet on Cardiovascular Disease Risk Factors: A Randomized Clinical Trial
Ana Rita Barbosa,
No information about this author
Sandra Pais,
No information about this author
Ana Marreiros
No information about this author
et al.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(15), P. 2443 - 2443
Published: July 26, 2024
Cardiovascular
diseases
(CVDs)
are
the
leading
cause
of
death
worldwide.
This
study
focused
on
evaluating
impact
a
Mediterranean-type
diet
combined
with
physical
exercise
CVD
risk
factors
high-risk
individuals.
A
randomized
clinical
trial
(RCT)
recruited
individuals
(≥50
years
old)
no
history
acute
myocardial
infarction,
but
high
criteria
according
to
SCORE2/SCORE2
OP.
Anthropometric
and
biochemical
parameters
were
assessed
at
baseline
after
12
weeks
intervention.
Participants
randomly
assigned
into
3
groups:
intervention
group
(Group
1a),
1b),
(±2
h/week)
plus
2).
Briefly,
dietary
was
based
principles
an
isocaloric
Mediterranean
(MD),
seven
main
meals/week
centered
plant-based
foods
(legumes
pulses).
The
effect
showed
significant
decrease
in
WC
(p
=
0.002),
BST
<
0.001),
visceral
fat
TG
0.029),
compared
control
groups.
significantly
increased
legume
intake
as
well
adherence
MD,
which
associates
0.024)
0.017).
should
be
endorsed
efficient
modifier
cardiometabolic
parameters.
Language: Английский
The Role of Human Gut Microbe Ruminococcus gnavus in Inflammatory Diseases
Progress In Microbes & Molecular Biology,
Journal Year:
2023,
Volume and Issue:
6(1)
Published: Dec. 29, 2023
Dysbiosis
is
a
prominent
factor
in
numerous
inflammatory
conditions,
with
Ruminococcus
gnavus,
prevalent
gut
microbe,
implicated
bowel
disease
(IBD),
irritable
syndrome
(IBS),
eczema,
metabolic
disorders,
and
rheumatic
diseases.
R.
gnavus
contributes
to
inflammation
by
producing
an
polysaccharide
degrading
mucin.
The
increasing
evidence
of
elevated
abundance
various
conditions
suggests
its
potential
as
therapeutic
target.
Despite
this,
there
are
limited
studies
on
treatment
strategies
targeting
gnavus.
This
article
provides
comprehensive
overview
the
association
between
diverse
highlighting
need
for
further
research
explore
effective
options
against
this
bacterium.
Language: Английский
Role of Nutraceuticals in Counteracting Inflammation in In Vitro Macrophages Obtained from Childhood Cancer Survivors
Alessandra Di Paola,
No information about this author
Maria Maddalena Marrapodi,
No information about this author
Elvira Pota
No information about this author
et al.
Cancers,
Journal Year:
2024,
Volume and Issue:
16(4), P. 714 - 714
Published: Feb. 8, 2024
The
advancement
of
anti-cancer
therapies
has
markedly
improved
the
survival
rate
children
with
cancer,
making
them
long-term
childhood
cancer
survivors
(CCS).
Nevertheless,
these
treatments
cause
a
low-grade
inflammatory
state,
determining
inflamm-aging
and,
thus,
favoring
early
onset
chronic
diseases
normally
associated
old
age.
Identification
novel
and
safer
therapeutic
strategies
is
needed
to
counteract
prevent
inflamm-aging.
Macrophages
are
cells
involved
in
immune
responses,
pivotal
role
iron
metabolism,
which
related
inflammation.
We
obtained
macrophages
from
CCS
patients
evaluated
their
phenotype
markers,
states,
metabolism
by
Western
blotting,
ELISA,
assays.
observed
strong
increase
classically
activated
markers
(M1)
alteration
CCS,
an
intracellular
concentration
markers.
These
results
suggest
that
prevalence
M1
could
be
worsening
inflammation
CCS.
Therefore,
we
propose
as
targets
To
avoid
toxic
regimens,
tested
some
nutraceuticals
(resveratrol,
curcumin,
oil-enriched
lycopene),
already
known
exert
anti-inflammatory
properties.
After
administration,
macrophage
switch
towards
M2,
well
reductions
pro-inflammatory
cytokines
concentration.
suggest—for
first
time—that
reduce
through
mechanism
action,
modulating
metabolism.
Language: Английский
Alcohol, health loss and mortality: can wine really save the good name of moderate alcohol consumption?
Polskie Archiwum Medycyny Wewnętrznej,
Journal Year:
2024,
Volume and Issue:
unknown
Published: March 20, 2024
It
is
estimated
that
one
third
of
the
world's
population
consumes
alcohol.At
same
time,
it
well-known
excessive
alcohol
consumption
in
leading
causes
premature
mortality.The
history
production
alcoholic
beverages,
especially
wine,
date
as
long
8000
years
ago.However,
humans
soon
realized
adverse
effects
abuse
and
tried
to
limit
its
consumption.Higher
associated
with
health
loss
increased
risk
all-cause
mortality.It
linearly
a
higher
many
types
cancers,
liver
disease,
incidence
atrial
fibrillation,
hemorrhagic
stroke,
heart
failure.Although,
scientific
societies
recommend
reduction
intake
specify
recommended
permissible
amount
consumed,
there
no
proven
safe
for
general
population.There
conflicting
data
on
effect
low
moderate
mortality
most
studies
indicating
J-shaped
curve
related
mostly
coronary
artery
disease
complications,
including
cardiovascular
death.Among
different
alcohol,
red
wine
may
have
effects,
due
abundance
antioxidative
polyphenols.Wine,
together
plant
foods,
olive
oil
fish
an
important
part
Mediterranean
diet.There
are
both
observational
randomized
documenting
wide
spectrum
health-promoting
such
diet,
major
events.People
who
want
drink
should
be
advised
their
minimum
consider
choosing
wine.
Language: Английский
The cardiovascular effects of coffee consumption: An overview
Elsevier eBooks,
Journal Year:
2024,
Volume and Issue:
unknown, P. 335 - 346
Published: Oct. 1, 2024
Language: Английский
Sex Differences in the Impact of BMI on Length of Hospital Stay in Hypertensive Patients Admitted to a Cardiology Department: A Retrospective Cohort Study
Vascular Health and Risk Management,
Journal Year:
2024,
Volume and Issue:
Volume 20, P. 579 - 591
Published: Dec. 1, 2024
Body
mass
index
(BMI),
as
a
straightforward
measure,
is
widely
used
in
clinical
practice,
and
its
results
are
linked
to
HT
patient
prognosis.
This
study
aimed
ascertain
if
sex
differences
exist
the
prognostic
significance
of
BMI
at
time
admission
cardiology
unit,
how
this
impacts
LOHS
for
patients
suffering
from
hypertension.
Language: Английский