Precision Neuronutrition: Personalized Approaches for Optimizing Brain Health DOI Creative Commons
Viacheslav N. Novikov, Anastasiia V. Badaeva, A B Danilov

et al.

Published: Oct. 31, 2023

Leveraging advancements in metabolomics and other cutting-edge technologies, precision neuronutrition aims to identify personalized nutrient requirements optimize brain health outcomes prevent neurological disorders. The main pathological mechanisms of disruption include neuroinflammation, oxidative stress, gut–brain disturbances deficiencies. Recent studies have identified biological markers for all those mechanisms. Precision interventions maintaining optimizing omega-3 fatty acids, vitamin B12, D, magnesium, coenzyme q10, polyphenols, l-carnitine, prebiotics probiotics. offers a promising approach through interventions. Continued research this field holds great potential improving outcomes.

Language: Английский

Micronutrients and their effects on Horticultural crop quality, productivity and sustainability DOI Creative Commons
Nazir Ahmed, Baige Zhang, Zaid Chachar

et al.

Scientia Horticulturae, Journal Year: 2023, Volume and Issue: 323, P. 112512 - 112512

Published: Oct. 13, 2023

Horticultural crop quality is an important aspect of agricultural production because it directly influences customer preference, market value, and overall sustainability. Micronutrients are for plant nutrition they affect the growth, development, horticultural crops. This review provides in-depth understanding role micronutrients in productivity. study investigated characteristics micronutrients, their functions growth most prevalent micronutrient deficits discusses obstacles issues associated with each treatment technique, including soil, foliar, fertigation application. It also emphasizes effects on quality, such as increased yield, improvements fruit attributes (size, color, flavor), nutritional value bioactive compounds, reduced postharvest losses, extended shelf life. Micronutrient plants have been studied, absorption, transport, accumulation, well interactions other nutrients signaling pathways. Recent research breakthroughs, studies specific synergies, innovative methods application formulation, developing technologies assessment, covered this review. The practical consequences recommendations management systems were investigated, concerns regarding sustainable efficient utilization future goals. Overall, underlines importance increasing productivity, potential influence subject.

Language: Английский

Citations

67

Sickle Cell Disease Update: New Treatments and Challenging Nutritional Interventions DOI Open Access
Victoria Bell, Theodoros Varzakas, Θεοδώρα Ψαλτοπούλου

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(2), P. 258 - 258

Published: Jan. 15, 2024

Sickle cell disease (SCD), a distinctive and often overlooked illness in the 21st century, is congenital blood disorder characterized by considerable phenotypic diversity. It comprises group of disorders, with sickle anemia (SCA) being most prevalent serious genotype. Although there have been some systematic reviews global data, worldwide statistics regarding SCD prevalence, morbidity, mortality remain scarce. In developed countries lower number patients, cutting-edge technologies led to development new treatments. However, developing settings where (SCD) more prevalent, medical management, rather than cure, still relies on use hydroxyurea, transfusions, analgesics. This that affects red cells, consequently affecting organs diverse manners. We discuss its etiology advent technologies, but aim this study understand various types nutrition-related studies involving individuals suffering from SCD, particularly Africa. The interplay environment, food, gut microbiota, along their respective genomes collectively known as microbiome, host metabolism responsible for mediating metabolic phenotypes modulating microbiota. addition, it serves purpose providing essential nutrients. Moreover, engages direct interactions homeostasis immune system, well indirect via metabolites. Nutrition interventions nutritional care are mechanisms addressing increased nutrient expenditures important aspects supportive management patients SCD. Underprivileged areas Sub-Saharan Africa should be accompanied efforts define promote Their importance key maintaining well-being quality life, especially because products limited, while native medicinal plant resources acknowledged.

Language: Английский

Citations

14

Local and Systemic Effects of Bioactive Food Ingredients: Is There a Role for Functional Foods to Prime the Gut for Resilience? DOI Creative Commons
Emma Jacquier, Marcel van de Wouw,

Elena Nekrasov

et al.

Foods, Journal Year: 2024, Volume and Issue: 13(5), P. 739 - 739

Published: Feb. 28, 2024

Scientific advancements in understanding the impact of bioactive components foods on gut microbiota and wider physiology create opportunities for designing targeted functional foods. The selection ingredients with potential local or systemic effects holds promise influencing overall well-being. An abundance studies demonstrate that show compositional changes correlate age disease. However, navigating this field, especially non-experts, remains challenging, given varying levels scientific substantiation. This narrative review addresses current knowledge host health, emphasizing resilience. It explores evidence related to extensive health benefits popular dietary ingredients, such as phytochemicals, fermented greens, fibres, prebiotics, probiotics, postbiotics. Importantly, distinguishes between both emerging ingredients. Additionally, it highlights how hormesis promotes resilience, fostering better adaptation stress—a hallmark health. By integrating examples bioactives, provides insights guide design evidence-based aimed at priming

Language: Английский

Citations

12

The Neurometabolic Function of the Dopamine–Aminotransferase System DOI Creative Commons
Sergey A. Apryatin

Metabolites, Journal Year: 2025, Volume and Issue: 15(1), P. 21 - 21

Published: Jan. 6, 2025

The neurometabolic function is controlled by a complex multi-level physiological system that includes neurochemical, hormonal, immunological, sensory, and metabolic components. Functional disorders of monoamine systems are often detected in clinical practice together with dysfunctions. An important part the mentioned pathological conditions associated disturbances protein metabolism, some most biomarkers which aminotransferases transcription factors regulate direct reactions. Another energy metabolism dopamine-mediated regulation metabolism. review describes research results into mechanism humans animals. Particular attention paid to mechanisms dopamine-aminotransferase separate, independent, regulatory diagnostically significant biochemical pathway hormonal system, key hormone cortisol, neurotransmitter dopamine, factor CREB, enzymes alanine aminotransferase, aspartate tyrosine aminotransferase. This presents an original study describing discovery new for A this system.

Language: Английский

Citations

1

Nutrient synergy: definition, evidence, and future directions DOI Creative Commons
Jeremy R. Townsend, Trevor O. Kirby, Philip A. Sapp

et al.

Frontiers in Nutrition, Journal Year: 2023, Volume and Issue: 10

Published: Oct. 12, 2023

Nutrient synergy refers to the concept that combined effects of two or more nutrients working together have a greater physiological impact on body than when each nutrient is consumed individually. While nutrition science traditionally focuses isolating single study their effects, it recognized interact in complex ways, and consumption can lead additive effects. Additionally, Dietary Reference Intakes (DRIs) provide guidelines prevent deficiencies excessive intake but are not designed assess potential synergistic consuming together. Even term often applied different manners depending scientific discipline. Considering these issues, aim this narrative review investigate health benefits supplements combination, we define as synergy, which has gained considerable attention for its overall well-being. We will examine how affects major bodily systems, influencing systemic health. address challenges associated with promoting conducting research topic, while proposing solutions enhance quality quantity literature synergy.

Language: Английский

Citations

19

Manuka Honey Inhibits Human Breast Cancer Progression in Preclinical Models DOI Open Access
Diana C. Márquez‐Garbán,

Cristian D. Yanes,

Gabriela Llarena

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(14), P. 2369 - 2369

Published: July 22, 2024

Manuka honey (MH) exhibits potential antitumor activity in preclinical models of a number human cancers. Treatment vitro with MH at concentrations ranging from 0.3 to 5.0% (

Language: Английский

Citations

7

The Role of Dietary Antioxidants, Food Supplements and Functional Foods for Energy Enhancement in Healthcare Professionals DOI Creative Commons

Theodora Kalogerakou,

Μαρία Αντωνιάδου

Antioxidants, Journal Year: 2024, Volume and Issue: 13(12), P. 1508 - 1508

Published: Dec. 10, 2024

Healthcare professionals frequently experience significant work overload, which often leads to substantial physical and psychological stress. This stress is closely linked increased oxidative a corresponding decline in energy levels. scoping review investigates the potential impact of dietary antioxidants food supplements conjunction with diet controlling these negative effects. Through an analysis biochemical pathways involved metabolism, paper emphasizes effectiveness targeted interventions. Key antioxidants, such as vitamins C E, polyphenols, carotenoids, are evaluated for their ability counteract enhance Additionally, assesses various supplements, including omega-3 fatty acids, coenzyme Q10, ginseng, mechanisms action enhancement. Practical guidelines incorporating energy-boost strategies into routine healthcare provided, emphasizing importance modifications reducing improving overall well-being performance high-stress environments. The concludes by suggesting directions future research validate findings explore new interventions that may further support under overload.

Language: Английский

Citations

5

Healthcare and non-healthcare professionals’ knowledge about nutrition in older adults: a cross-sectional study DOI Creative Commons
Marijana Matek Sarić,

Tamara Sorić,

Ana Sarić

et al.

BMC Public Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 24, 2025

Malnutrition frequently affects older adults, increasing their risk for numerous diseases, as well healthcare costs. Therefore, nutritional assessment and appropriate support addressed to meet individual needs prevent malnutrition its consequences should be a fundamental part of adults. This study aimed compare the knowledge nutrition guidelines adults between non-healthcare professionals working with The was conducted during May June 2021 using validated "Knowledge adults" questionnaire designed by Andrija Stampar Teaching Institute Public Health, Croatia. participants were recruited from various institutions providing care in Split-Dalmatia Dubrovnik-Neretva County. final convenience sample consisted 214 (163 51 professionals). obtained results analyzed descriptive inferential statistics. associations participants' characteristics about importance disease prevention treatment, status clinical multiple linear regression models. Participants' overall moderate both groups, scoring median 7.0 (IQR = 1.0) 6.0 2.0). Compared professionals, had lower treatment (β − 0.16; p 0.024). No statistically significant differences found level 0.02; 0.769) 0.08; 0.267). highlights gaps regarding dietary among this specific population group. These findings suggest that targeted educational programs might needed improve understanding geriatric nutrition.

Language: Английский

Citations

0

Comparative analysis of amino acid, proximate and mineral compositions of Persea americana seeds and Telfairia occidentalis seeds formulated diet DOI
Ovigueroye Ekayoda, Helen Ejiro Kadiri, Augustine Apiamu

et al.

Food and Humanity, Journal Year: 2025, Volume and Issue: unknown, P. 100564 - 100564

Published: March 1, 2025

Language: Английский

Citations

0

Medicinal value of some horticultural crops DOI

Tuba Dilmaçünal

Studies in natural products chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 283 - 393

Published: Jan. 1, 2025

Language: Английский

Citations

0