A novel TICT-based molecular rotor: synthesis, crystal structure and application in high resolution imaging of sweat pores DOI

Sanjeev Kumar,

Balkaran Singh Sran,

Dharmendra Gahalot

et al.

Journal of Materials Chemistry C, Journal Year: 2024, Volume and Issue: 12(48), P. 19424 - 19434

Published: Jan. 1, 2024

We report the synthesis and crystal structure of a naphthalimide–methoxyquinoline (NI–HQ) based molecular rotor for visualizing sweat pores without degradation dsDNA present in sweat.

Language: Английский

Recent Advances in Micro- and Nano-Drug Delivery Systems Based on Natural and Synthetic Biomaterials DOI Open Access
Md. Harun-Or-Rashid,

Most. Nazmin Aktar,

Md. Sabbir Hossain

et al.

Polymers, Journal Year: 2023, Volume and Issue: 15(23), P. 4563 - 4563

Published: Nov. 28, 2023

Polymeric drug delivery technology, which allows for medicinal ingredients to enter a cell more easily, has advanced considerably in recent decades. Innovative medication strategies use biodegradable and bio-reducible polymers, progress the field been accelerated by future possible research applications. Natural polymers utilized polymeric systems include arginine, chitosan, dextrin, polysaccharides, poly(glycolic acid), poly(lactic hyaluronic acid. Additionally, poly(2-hydroxyethyl methacrylate), poly(N-isopropyl acrylamide), poly(ethylenimine), dendritic bioabsorbable as well biomimetic bio-related drug-free macromolecular therapies have employed delivery. Different synthetic natural biomaterials are clinical phase mitigate different diseases. Drug methods using becoming increasingly common pharmaceutical industry, with biocompatible copolymers dendrimers having helped cure cancer systems. This review discusses all above components how, combining biological approaches, micro- nano-drug can result revolutionary gene devices.

Language: Английский

Citations

27
Unraveling the structure–property relationships in fluorescent phenylhydrazones: the role of substituents and molecular interactions DOI Creative Commons
Paulina Sobczak, Tomasz Sierański, Marcin Świa̧tkowski

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(3), P. 1514 - 1526

Published: Jan. 1, 2025

This study investigates the structure-property relationships of a series phenylhydrazones bearing various electron-donating and electron-withdrawing substituents, such as methoxy, dimethylamino, morpholinyl, hydroxyl, chloro, bromo, nitro groups. The compounds were synthesized, their structures characterized using single-crystal X-ray diffraction, powder FTIR spectroscopy, NMR DSC. Three-dimensional excitation-emission matrix (3D-EEM) fluorescence spectroscopy UV-Vis employed to elucidate complex interplay between molecular skeleton, resulting photophysical properties. Quantum mechanical calculations provided further insights into electronic structure excited-state dynamics investigated compounds. exhibited emission wavelengths ranging from 438 482 nm, with backbone playing crucial role in determining wavelength. incorporation methoxy dimethylamino groups, led enhanced intensity, while presence resulted complete quenching. comprehensive establishes rational design principles for development highly emissive tuned properties highlights significance skeleton dictating behavior this class

Language: Английский

Citations

1
Water-Soluble Small Organic Fluorophores for Oncological Theragnostic Applications: Progress and Development DOI
Ashanul Haque, Khalaf M. Alenezi, Abdulmohsen Khalaf Dhahi Alsukaibi

et al.

Topics in Current Chemistry, Journal Year: 2024, Volume and Issue: 382(2)

Published: April 26, 2024

Language: Английский

Citations

5
Recent advances in small-molecules fluorescent probes bearing Salicylaldehyde unit and their sensing & bio-imaging applications DOI
Avijit Ghosh, Arghya Adhikary

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: 1317, P. 139086 - 139086

Published: June 21, 2024

Language: Английский

Citations

5
Design and Screening of Fluorescent Probes Based upon Hemicyanine Dyes for Monitoring Mitochondrial Viscosity in Living Cells DOI
Xiufeng Zhang,

Xiaoying Ma,

Buyue Zhang

et al.

The Journal of Physical Chemistry B, Journal Year: 2024, Volume and Issue: 128(16), P. 3910 - 3918

Published: April 12, 2024

Viscosity, at the subcellular level, plays a crucial role as physicochemical factor affecting microenvironment homeostasis. Abnormal changes in mitochondrial viscosity often lead to various diseases organism. Based on twisted intramolecular charge transfer mechanism, four hemicyanine dye fluorescent probes (HT-SA, HT-SA-S, HT-Bzh, and HT-NA) were designed synthesized for response. The single bond between nitrogen-containing heterocycle carbon–carbon double structure of probe served response site. Finally, HT-Bzh was screened optimal according its responsiveness, targeting, interference resistance. fluorescence intensity increased 22-fold when from 13.75 811.2 cP. In summary, all we have developed can be used different applications depending external environment, providing valuable reference design potential tools address monitoring biological systems.

Language: Английский

Citations

4
Recent Progress in ESIPT-Based Fluorescent Chemosensors for Detection of Zn2+, Mg2+ and Cu2+ DOI
Hossein Roohi

Dyes and Pigments, Journal Year: 2024, Volume and Issue: unknown, P. 112509 - 112509

Published: Oct. 1, 2024

Language: Английский

Citations

4
Comparison of methods for rapid assessment of selectivity and efficiency of the analytical signal of fluorescent phases of different natures DOI
Т. А. Кучменко,

D. Yu. Vandychev,

V. V. Yagov

et al.

Журнал аналитической химии, Journal Year: 2025, Volume and Issue: 79(7), P. 782 - 799

Published: Jan. 6, 2025

Language: Английский

Citations

0
Unraveling the mechanisms underlying the fluorescent probe detection of microcystin-LR and its binding with CT-DNA DOI
Huixia Zhang,

Jun Chen,

Ping Xie

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 139873 - 139873

Published: Jan. 1, 2025

Language: Английский

Citations

0
Carbamate‐Functionalized NLOphores via a Formal [2+2] Cycloaddition‐Retroelectrocyclization Strategy DOI Creative Commons
İpek Savaş, M. Çelik, Alberto Barsella

et al.

Chemistry - A European Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 23, 2025

This study introduces a new donor group capable of activating click-type [2+2] cycloaddition-retroelectrocyclizations, generally known for their limited scope. Target chromophores were synthesized using isocyanate-free urethane synthesis. The developed synthetic method allows the tuning optical properties by modifying groups, acceptor units, and side chains. charge transfer (CT) bands exhibit λmax values ranging from 363 to 692 nm. CT observed have been supported solvatochromism protonation experiments. compounds positive solvatochromism. Due potential as NLOphore candidates, stability investigated both experimentally through TGA theoretically calculating parameters such frontier orbital energy differences, electronegativity, global hardness/softness. TD-DFT calculations used elucidate nature electronic transitions, revealing that correspond arising HOMO-to-LUMO excitations. NLO DFT methods EFISHG technique. Both results are shown be in agreement with HOMO-LUMO differences. experimental μβ selected molecules range 470×10-48 5400×10-48 esu.

Language: Английский

Citations

0
Design strategies of fluorescent covalent organic frameworks and visual on-site monitoring of food freshness: A state-of-the-art review DOI

Dianwei Zhang,

Kexin Li, Shengnan Wang

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2025, Volume and Issue: 187, P. 118226 - 118226

Published: March 3, 2025

Language: Английский

Citations

0