Pharmaceutics,
Journal Year:
2023,
Volume and Issue:
15(6), P. 1674 - 1674
Published: June 7, 2023
The
therapeutic
efficiency
of
plant
extracts
has
been
limited
by
their
poor
pharmaceutical
availability.
Hydrogels
have
promising
potential
to
be
applied
as
wound
dressings
due
high
capacity
absorb
exudates
and
enhanced
performance
in
loading
releasing
extracts.
In
this
work,
pullulan/poly
(vinyl
alcohol)
(P/PVA)
hydrogels
were
first
prepared
using
an
eco-friendly
method
based
on
both
a
covalent
physical
cross-linking
approach.
Then,
the
loaded
with
hydroalcoholic
extract
Calendula
officinalis
simple
post-loading
immersion
method.
Different
capacities
investigated
terms
physico-chemical
properties,
chemical
composition,
mechanical
water
absorption.
exhibited
hydrogen
bonding
interactions
between
polymer
extract.
retention
well
properties
decreased
increase
amount
hydrogel.
However,
higher
amounts
hydrogel
improved
bioadhesiveness.
release
from
was
controlled
Fickian
diffusion
mechanism.
Extract-loaded
expressed
antioxidant
activity,
reaching
70%
DPPH
radical
scavenging
after
15
min
buffer
solution
at
pH
5.5.
Additionally,
showed
antibacterial
activity
against
Gram-positive
Gram-negative
bacteria
non-cytotoxic
HDFa
cells.
Cureus,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Feb. 28, 2024
Wound
healing
is
an
evolving
and
intricate
technique
that
vital
to
the
restoration
of
tissue
integrity
function.
Over
past
few
decades,
chitosan
a
biopolymer
derived
from
chitin,
became
known
as
emerging
biomaterial
in
field
wounds
due
its
distinctive
characteristics
including
biocompatibility,
biodegradability,
affinity
biomolecules,
wound-healing
activity.
This
natural
polymer
exhibits
excellent
capabilities
by
accelerating
development
new
skin
cells,
reducing
inflammation,
preventing
infections.
Due
distinct
biochemical
innate
antibacterial
activity,
has
been
extensively
researched
wound
dressing.
Chronic
wounds,
such
diabetic
ulcers
liver
disease,
are
growing
medical
problem.
Chitosan-based
biomaterials
promising
solution
domain
care.
The
article
analyzes
depth
chitosan-based
their
impact
on
also
methods
enhance
advantages
incorporating
bioactive
compounds.
literature
review
aimed
improve
understanding
knowledge
about
use
healing.
Journal of Materials Chemistry B,
Journal Year:
2024,
Volume and Issue:
12(33), P. 7977 - 8006
Published: Jan. 1, 2024
The
objective
of
this
review
is
to
provide
an
up-to-date
and
all-encompassing
account
the
recent
advancements
in
domain
interactive
wound
dressings.
Considering
gap
between
achieved
desired
clinical
outcomes
with
currently
available
or
under-study
healing
therapies,
newer
more
specific
options
based
on
type
phase
are
reviewed.
Starting
from
comprehensive
description
process,
a
detailed
classification
dressings
presented.
Subsequently,
we
present
elaborate
significant
discussion
describing
(unconventional)
Latter
includes
biopolymer-based,
bioactive-containing
biosensor-based
smart
dressings,
which
discussed
separate
sections
together
their
applications
limitations.
Moreover,
(2-5
years)
trials,
patents
unconventional
marketed
products,
other
information
advanced
care
designs
techniques
discussed.
future
research
direction
highlighted,
peptides,
proteins,
human
amniotic
membranes
as
potential
Finally,
conclude
that
field
needs
further
development
offers
scope
for
integrating
process
technologies.
Gels,
Journal Year:
2025,
Volume and Issue:
11(2), P. 123 - 123
Published: Feb. 7, 2025
Recent
advancements
in
wound
dressing
materials
have
significantly
improved
acute
and
chronic
management
by
addressing
challenges
such
as
infection
control,
moisture
balance,
enhanced
healing.
Important
progress
has
been
made,
especially
with
hydrogels,
foams,
antimicrobial
for
creating
optimized
dressings.
Hydrogels
are
known
maintaining
optimal
levels,
while
foam
dressings
excellent
exudate
absorbents.
Meanwhile,
incorporates
various
agents
to
reduce
risks.
These
options
healing
time
focusing
on
customized
patient
needs.
Therefore,
this
review
highlights
the
newest
research
prototypes
applications,
emphasizing
their
particular
benefits
clinical
importance.
Innovations
stimuli-responsive
hydrogels
hybrid
bioengineered
composites
discussed
relation
properties,
including
responsiveness
pH,
temperature,
glucose,
or
enzymes
drug
delivery
precision.
Moreover,
ongoing
trials
included,
demonstrating
potential
of
emerging
solutions
be
soon
translated
from
laboratory
settings.
By
discussing
interdisciplinary
approaches
that
integrate
advanced
materials,
nanotechnology,
biological
insights,
work
provides
a
contemporary
framework
patient-centric,
efficient
care
strategies.
Journal of Composites Science,
Journal Year:
2025,
Volume and Issue:
9(3), P. 133 - 133
Published: March 13, 2025
Severe
skin
injuries
such
as
burns
and
chronic
wounds
are
a
subject
of
interest
in
the
medical
field,
they
require
much
attention.
These
types
susceptible
to
serious
complications,
which
can
worsen
health
patients
reduce
their
quality
life.
Hydrogels
have
emerged
innovative
wound
dressings
for
treating
acute
wounds,
including
burns,
diabetic
foot
ulcers,
venous
leg
pressure
ulcers.
polymeric
networks
provide
moist
environment,
promote
cellular
migration,
offer
antimicrobial
properties,
being
recognized
superior
conventional
dressings.
This
review
aims
explore
recent
advancements
hydrogel-based
dressings,
emphasizing
state-of-the-art
technologies
used
this
purpose
trend
achieving
personalized
therapeutic
approaches.
Despite
promising
vitro
vivo
findings
described
review,
further
clinical
validation
large-scale
manufacturing
optimizations
required
widespread
adoption.
Polymers,
Journal Year:
2022,
Volume and Issue:
14(21), P. 4670 - 4670
Published: Nov. 2, 2022
Bacterial
cellulose
(BC)
is
currently
one
of
the
most
popular
environmentally
friendly
materials
with
unique
structural
and
physicochemical
properties
for
obtaining
various
functional
a
wide
range
applications.
In
this
regard,
literature
reporting
on
bacterial
nanocellulose
has
increased
exponentially
in
past
decade.
Currently,
extensive
investigations
aim
at
promoting
manufacturing
BC-based
nanocomposites
other
components
such
as
nanoparticles,
polymers,
biomolecules,
that
will
enable
to
develop
advanced
novel
functionalities.
However,
commercial
production
limited
by
high
cost
low
yield
BC,
lack
highly
efficient
industrial
technologies
well.
Therefore,
present
review
aimed
studying
current
data
field
BC
purpose
its
further
usage
obtain
polymer
nanocomposites.
The
highlights
progress
synthesizing
their
applications
biomedical
fields,
wound
healing,
drug
delivery,
tissue
engineering.
nanocellulose-based
biosensors
adsorbents
were
introduced
herein.
ACS Polymers Au,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 10, 2025
Nanofibers
fabricated
from
various
materials
such
as
polymers,
carbon,
and
semiconductors
have
been
widely
used
for
wound
healing
tissue
engineering
applications
due
to
their
excellent
nontoxic,
biocompatible,
biodegradable
properties.
with
a
diameter
in
the
nanometer
range
possess
larger
surface
area
per
unit
mass
permitting
easier
addition
of
functionalities
release
biotherapeutics
incorporated
compared
conventional
polymeric
microfibers.
Henceforth,
nanofibers
are
choice
fabricating
scaffolds
management
healing.
Nanofibrous
emerged
promising
method
dressings
since
they
mimic
fibrous
dermal
extracellular
matrix
milieu
that
offers
structural
support
functional
signals
guiding
regeneration.
Cellulose-based
gained
significant
attention
among
researchers
fabrication
on-site
fortified
Cellulose
is
linear,
stereoregular
insoluble
polymer
built
repeated
units
d-glucopyranose
linked
1,4-β
glycoside
bonds
complex
multilevel
supramolecular
architecture.
has
by
its
solubility
many
solvents
capacity
self-assembly
into
nanofibers,
facilitating
mimicry
natural
architecture
promoting
substantial
water
retention.
It
also
abundant
demonstrates
low
immunogenicity
humans
nonanimal
origins.
To
this
end,
cellulose-based
studied
protein
delivery,
antibacterial
activity,
biosensor
applications,
others.
Taken
together,
review
delves
an
update
on
fused
bioactive
compounds
not
explored
considerably
past
few
years.
