Additive manufacturing of biodegradable magnesium-based materials: Design strategies, properties, and biomedical applications

Journal of Magnesium and Alloys, Journal Year: 2023, Volume and Issue: 11(3), P. 801 - 839

Published: Jan. 5, 2023

Magnesium (Mg)-based materials are a new generation of alloys with the exclusive ability to be biodegradable within human/animal body. In addition biodegradability, their inherent biocompatibility and similar-to-bone density make Mg-based good candidates for fabricating surgical bioimplants use in orthopedic traumatology treatments. To this end, nowadays additive manufacturing (AM) along three-dimensional (3D) printing represents promising technique as it allows integration bioimplant design processes specific given applications. Meanwhile, also faces many challenges associated properties alloys, including high chemical reactivity, potential combustion, low vaporization temperature. review article, various AM fabricate biomedical implants from metallic microstructure, mechanical properties, biocompatibility, antibacterial well post-AM treatments were critically reviewed. Also, issues involved perspectives design, applications identified; possibilities scope scaffolds/implants discussed highlighted.

Language: Английский

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Bioadhesive Technology Platforms

Chemical Reviews, Journal Year: 2023, Volume and Issue: 123(24), P. 14084 - 14118

Published: Nov. 16, 2023

Bioadhesives have emerged as transformative and versatile tools in healthcare, offering the ability to attach tissues with ease minimal damage. These materials present numerous opportunities for tissue repair biomedical device integration, creating a broad landscape of applications that captivated clinical scientific interest alike. However, fully unlocking their potential requires multifaceted design strategies involving optimal adhesion, suitable biological interactions, efficient signal communication. In this Review, we delve into these pivotal aspects bioadhesive design, highlight latest advances applications, identify lie ahead bioadhesives multifunctional technology platforms.

Language: Английский

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Nano-hydroxyapatite (nHAp) scaffolds for bone regeneration: Preparation, characterization and biological applications

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 95, P. 105601 - 105601

Published: March 18, 2024

Language: Английский

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Antibacterial PLA/Mg composite with enhanced mechanical and biological performance for biodegradable orthopedic implants

Biomaterials Advances, Journal Year: 2023, Volume and Issue: 152, P. 213523 - 213523

Published: June 16, 2023

Language: Английский

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3D Bioprinting for Vascularization

Bioengineering, Journal Year: 2023, Volume and Issue: 10(5), P. 606 - 606

Published: May 18, 2023

In the world of clinic treatments, 3D-printed tissue constructs have emerged as a less invasive treatment method for various ailments. Printing processes, scaffold and free materials, cells used, imaging analysis are all factors that must be observed in order to develop successful 3D clinical applications. However, current research bioprinting model development lacks diverse methods vascularization result issues with scaling, size, variations printing method. This study analyzes printing, bioinks techniques vascularization. These discussed evaluated determine most optimal strategies Integrating stem endothelial prints, selecting type bioink according its physical properties, choosing properties desired printed steps will aid bioprinted

Language: Английский

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3D printed scaffolds based on hyaluronic acid bioinks for tissue engineering: a review

Biomaterials Research, Journal Year: 2023, Volume and Issue: 27(1)

Published: Feb. 9, 2023

Hyaluronic acid (HA) is widely distributed in human connective tissue, and its unique biological physicochemical properties ability to facilitate structure repair make it a promising candidate for three-dimensional (3D) bioprinting the field of tissue regeneration biomedical engineering. Moreover, HA an ideal raw material bioinks engineering because histocompatibility, non-immunogenicity, biodegradability, anti-inflammatory properties, anti-angiogenic modifiability. Tissue multidisciplinary focusing on vitro reconstructions mammalian tissues, such as cartilage engineering, neural skin other areas that require further clinical applications. In this review, we first describe modification methods, cross-linking strategies derivatives then critically discuss strengths, shortcomings, feasibility each method. Subsequently, reviewed practical applications outcomes bioink 3D bioprinting. Finally, challenges opportunities development provide research references insights.

Language: Английский

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Remediation of acetamiprid pesticide from contaminated water by antibacterial biosorbent based on carboxymethyl tragacanth-grafted-poly(3-aminophenol) decorated with ZnO@Fe3O4

Environmental Research, Journal Year: 2024, Volume and Issue: 252, P. 118893 - 118893

Published: April 9, 2024

Language: Английский

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Ulva Seaweed-Derived Ulvan: A Promising Marine Polysaccharide as a Sustainable Resource for Biomaterial Design

Marine Drugs, Journal Year: 2025, Volume and Issue: 23(2), P. 56 - 56

Published: Jan. 24, 2025

Green seaweed is currently underused compared with other major types. Many scientists have reported applications of the green Ulva in various fields recent years, which makes it a candidate for biomass production industrial biorefineries. contains unique polysaccharide called ulvan, being considered medicinal and pharmacological applications. Ulvan sulfated including rhamnose glucuronic acid residues, has range bioactivities, immunomodulatory, antimicrobial, anticoagulant properties. The biocompatibility ulvan versatile biomaterial design. This review presents an in-depth analysis potential starting extraction methods structural/biological characterization moving on to We also highlight advantages over traditional polysaccharides such as agar, carrageenan, alginate.

Language: Английский

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Bacterial Cellulose/Cellulose Imidazolium Bio-Hybrid Membranes for In Vitro and Antimicrobial Applications

Journal of Functional Biomaterials, Journal Year: 2023, Volume and Issue: 14(2), P. 60 - 60

Published: Jan. 20, 2023

In biomedical applications, bacterial cellulose (BC) is widely used because of its cytocompatibility, high mechanical properties, and ultrafine nanofibrillar structure. However, use neat BC often limited due to lack antimicrobial properties. the current article, we proposed a novel technique for preparing cationic hydrogel through in situ incorporation water-soluble derivative, bearing imidazolium tosylate function group (Cell-IMD), media preparation. Different concentrations derivative (2, 4, 6%) were embedded into highly inter-twined network biosynthesis until forming gels. Cationic functionalization was deeply examined by Fourier transform infrared (FT-IR), NMR spectroscopy, scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), diffraction (XRD) methods. vitro studies with L929 cells confirmed good cytocompatibility BC/cationic derivatives, significant increase cell proliferation after 7 days, case BC/Cell-IMD3 groups. Finally, assessment against Staphylococcus aureus, Streptococcus mutans, Candida albicans assessed, recording sensitivity higher concentration derivative. All results suggest promising hybrid materials bio-sustainable applications (i.e., food packaging).

Language: Английский

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Additive manufacturing of magnesium alloys and its biocompatibility

Bioprinting, Journal Year: 2023, Volume and Issue: 36, P. e00318 - e00318

Published: Oct. 26, 2023

Language: Английский

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