Nano Letters,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 22, 2025
Single-functional
wound
dressings
provide
limited
therapeutic
benefits
for
chronic
healing.
Effective
care
wounds
requires
a
multifunction
that
integrates
exudate
management,
treatment,
and
continuous
monitoring.
Here,
we
introduce
an
integrated
Janus
bioelectronic
bandage
designed
to
achieve
self-pumping
management
via
electrospinning
dressing
with
opposite
wettability,
antibacterial
properties
through
silver
nanoparticles
(AgNPs),
the
monitoring
of
multiplex
biomarkers
in
electrochemical
sensors
positioned
on
drainage
side.
The
limits
detection
(LOD)
are
0.15
mM
glucose,
6.85
μM
UA,
60.76
mV/decade
pH
(4–8),
respectively.
We
demonstrated
mice
full-thickness
models
this
effectively
promoted
healing,
achieving
closure
rate
90.35%
day
14,
monitored
dynamic
changes
three
within
situ
over
period
3
days.
Materials,
Journal Year:
2024,
Volume and Issue:
17(2), P. 278 - 278
Published: Jan. 5, 2024
Effective
wound
treatment
has
become
one
of
the
most
important
challenges
for
healthcare
as
it
continues
to
be
leading
causes
death
worldwide.
Therefore,
care
technologies
significantly
evolved
in
order
provide
a
holistic
approach
based
on
various
designs
functional
dressings.
Among
them,
hydrogels
have
been
widely
used
due
their
biocompatibility
and
similarity
extracellular
matrix.
The
hydrogel
formula
offers
control
an
optimal
moisture
level
its
ability
absorb
excess
fluid
from
or
release
needed.
Additionally,
can
successfully
integrated
with
plethora
biologically
active
components
(e.g.,
nanoparticles,
pharmaceuticals,
natural
extracts,
peptides),
thus
enhancing
performance
resulting
composite
healing
applications.
In
this
review,
the-state-of-the-art
discoveries
related
stimuli-responsive
hydrogel-based
dressings
summarized,
taking
into
account
antimicrobial,
anti-inflammatory,
antioxidant,
hemostatic
properties,
well
other
effects
re-epithelialization,
vascularization,
restoration
tissue)
use.
Gels,
Journal Year:
2025,
Volume and Issue:
11(2), P. 123 - 123
Published: Feb. 7, 2025
Recent
advancements
in
wound
dressing
materials
have
significantly
improved
acute
and
chronic
management
by
addressing
challenges
such
as
infection
control,
moisture
balance,
enhanced
healing.
Important
progress
has
been
made,
especially
with
hydrogels,
foams,
antimicrobial
for
creating
optimized
dressings.
Hydrogels
are
known
maintaining
optimal
levels,
while
foam
dressings
excellent
exudate
absorbents.
Meanwhile,
incorporates
various
agents
to
reduce
risks.
These
options
healing
time
focusing
on
customized
patient
needs.
Therefore,
this
review
highlights
the
newest
research
prototypes
applications,
emphasizing
their
particular
benefits
clinical
importance.
Innovations
stimuli-responsive
hydrogels
hybrid
bioengineered
composites
discussed
relation
properties,
including
responsiveness
pH,
temperature,
glucose,
or
enzymes
drug
delivery
precision.
Moreover,
ongoing
trials
included,
demonstrating
potential
of
emerging
solutions
be
soon
translated
from
laboratory
settings.
By
discussing
interdisciplinary
approaches
that
integrate
advanced
materials,
nanotechnology,
biological
insights,
work
provides
a
contemporary
framework
patient-centric,
efficient
care
strategies.
Journal of Composites Science,
Journal Year:
2025,
Volume and Issue:
9(3), P. 133 - 133
Published: March 13, 2025
Severe
skin
injuries
such
as
burns
and
chronic
wounds
are
a
subject
of
interest
in
the
medical
field,
they
require
much
attention.
These
types
susceptible
to
serious
complications,
which
can
worsen
health
patients
reduce
their
quality
life.
Hydrogels
have
emerged
innovative
wound
dressings
for
treating
acute
wounds,
including
burns,
diabetic
foot
ulcers,
venous
leg
pressure
ulcers.
polymeric
networks
provide
moist
environment,
promote
cellular
migration,
offer
antimicrobial
properties,
being
recognized
superior
conventional
dressings.
This
review
aims
explore
recent
advancements
hydrogel-based
dressings,
emphasizing
state-of-the-art
technologies
used
this
purpose
trend
achieving
personalized
therapeutic
approaches.
Despite
promising
vitro
vivo
findings
described
review,
further
clinical
validation
large-scale
manufacturing
optimizations
required
widespread
adoption.
Journal of Nanobiotechnology,
Journal Year:
2025,
Volume and Issue:
23(1)
Published: Jan. 31, 2025
The
orderly
regulation
of
immune
inflammation
and
promotion
the
regeneration
skin
vessels
fibers
are
key
to
treatment
diabetic
injury
(DSI).
Although
various
traditional
polypeptide
biological
dressings
continue
be
developed,
their
efficacy
is
not
satisfactory.
In
recent
years,
plant-to-mammal
has
provided
an
effective
approach
for
chronic
wound
management,
but
development
plant-based
treatments
remains
challenging.
exosomes
from
Chinese
herbs
promising
healing.
this
study,
plant
derived
lemons
(Citrus
limon)
were
extracted,
was
verified.
Lemon
regulated
polarization
reprogramming
macrophages,
promoted
proliferation
migration
vascular
endothelial
cells
fibroblasts,
thus
healing
wounds.
To
solve
problems
continuous
drug
delivery
penetration
depth,
Exosomes
loaded
into
a
hydrogel
constructed
Gelatin
Methacryloyl
(GelMA)
Dialdehyde
Starch
(DAS)
that
closely
fits
skin,
absorbs
water,
swells,
moist
breathable,
effectively
promoting
sustained
slow
release
resulting
in
excellent
performance
Our
GelMA-DAS-Lemon
(GelMA/DAS/Exo
hydrogel)
patch
represents
potentially
valuable
option
repairing
wounds
clinical
applications.
Abstract
With
the
aging
and
obesity
era,
increasing
incidence
of
diabetes
diabetic
complications,
especially
non‐healing
wounds,
imposes
a
serious
economic
burden
on
both
patients
society.
The
complex
microenvironments,
including
hyperglycemia,
bacterial
infection,
ischemia,
nerve
damage,
lead
to
prolonged
inflammation
proliferation
phase
wounds.
Mesenchymal
stem
cell‐derived
small
extracellular
vesicles
(MSC‐sEVs),
which
contain
rich
variety
therapeutic
molecules,
have
been
chased
for
decades
because
their
potential
roles
in
cellular
communication,
tissue
regeneration,
drug
delivery.
As
powerful
tools
controlled‐sustained
release
sEVs,
biocompatible
hydrogels
applied
wide
range
biomedical
applications.
Herein,
we
first
summarize
pathological
features
such
as
angiopathy,
neuropathy,
immune
cell
dysfunction.
Then,
discuss
biological
properties,
performance,
stability
pure
MSC‐sEVs.
After
that,
components,
application
patterns,
responsiveness
hydrogels.
Next,
loading
avenues
MSC‐sEVs
into
hydrogel,
behaviors
sEVs
from
hydrogels,
influence
crosslinking
method
hydrogel‐sEV
composites.
Finally,
provide
an
overview
current
applications
loaded
with
novel
cell‐free
engineering
system
managing
wounds
propose
critical
unsolved
issues.
This
review
is
expected
meaningful
guidance
developing
wound
management.
