Recent advances in near-infrared stimulated nanohybrid hydrogels for cancer photothermal therapy DOI
Yongjun Hu,

Yi Zhou,

Kaichun Li

et al.

Biomaterials Science, Journal Year: 2024, Volume and Issue: 12(18), P. 4590 - 4606

Published: Jan. 1, 2024

Nanomedicine has emerged as a promising avenue for advancing cancer treatment, but the challenge of mitigating its in vivo side effects necessitates development innovative structures and materials. Recent investigation unveiled nanogels particularly compelling candidates, characterized by porous, three-dimensional network architecture that exhibits exceptional drug loading capacity. Beyond this, boast substantial specific surface area can be tailored with chemical functionalities. Consequently, are frequently engineered multi-modal synergistic platform combating cancer, wherein photothermal therapy stands out due to capacity penetrate deep tissues achieve localized tumor eradication through application elevated temperatures. In this review, we delve into synthesis diverse varieties capable controlled release triggered either or physical stimuli. It also summarizes their potential integration alongside other therapeutic modalities realize effective ablation. Moreover, analyze primary mechanisms underlying contribution treatment while underscoring adeptness regulating temperatures repairing bone defects resulting from tumor-associated trauma. Envisioned an auspicious strategy realm therapy, hold promise furnishing delivery precise thermal ablation capabilities.

Language: Английский

Metallic nanoparticles unveiled: Synthesis, characterization, and their environmental, medicinal, and agricultural applications DOI
Mohammad Tahir Aminzai, Metin Yıldırım, Erdal Yabalak

et al.

Talanta, Journal Year: 2024, Volume and Issue: 280, P. 126790 - 126790

Published: Aug. 29, 2024

Language: Английский

Citations

17
Advanced Nanomaterials for Cancer Therapy: Gold, Silver, and Iron Oxide Nanoparticles in Oncological Applications DOI Creative Commons
Priyanka Singh, Santosh Pandit, Sri Renukadevi Balusamy

et al.

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 14(4)

Published: Nov. 6, 2024

Cancer remains one of the most challenging health issues globally, demanding innovative therapeutic approaches for effective treatment. Nanoparticles, particularly those composed gold, silver, and iron oxide, have emerged as promising candidates changing cancer therapy. This comprehensive review demonstrates landscape nanoparticle-based oncological interventions, focusing on remarkable advancements potentials oxide nanoparticles. Gold nanoparticles garnered significant attention their exceptional biocompatibility, tunable surface chemistry, distinctive optical properties, rendering them ideal various diagnostic strategies. Silver nanoparticles, renowned antimicrobial exhibit potential in therapy through multiple mechanisms, including apoptosis induction, angiogenesis inhibition, drug delivery enhancement. With magnetic properties offer unique diagnosis targeted opportunities. critically examines recent synthesis, functionalization, biomedical applications these Moreover, challenges are discussed, toxicity concerns, immunogenicity, translational barriers, ongoing efforts to overcome hurdles highlighted. Finally, insights into future directions regulatory considerations, provided aiming accelerate translation technologies from bench bedside.

Language: Английский

Citations

13
New Nanoparticle-Based Drug: A 2024 Update and Future Prospects DOI
Hannah R. Martin, Horacio Bach

BioNanoScience, Journal Year: 2025, Volume and Issue: 15(3)

Published: May 19, 2025

Language: Английский

Citations

0
Biotechnological advances in microbial synthesis of gold nanoparticles: Optimizations and applications DOI
Jyoti Verma, Chitranjan Kumar, Monica Sharma

et al.

3 Biotech, Journal Year: 2024, Volume and Issue: 14(11)

Published: Oct. 7, 2024

Language: Английский

Citations

2
Overview of chitin dissolution, hydrogel formation and its biomedical applications DOI

Kavipriya Murugaiyan,

M. Vishnu Priya, Hiroshi Tamura

et al.

Journal of Biomaterials Science Polymer Edition, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 32

Published: Dec. 20, 2024

Chitin hydrogel and hydrogel-based products are some of the frequently reported biomaterials for biomedical applications. Yet there is a void in understanding chitin's dissolution mechanism its most suitable solvent system(s). natural polysaccharide polymer which can be dissolved solvents such as calcium chloride- methanol, sodium hydroxide/urea (NaOH/urea), lithium chloride diacetamide (LiCl/DMAc), ionic liquids deep eutectic solvents. Among alkali/urea systems NaOH/urea, KOH/urea, LiOH/urea chitin we will focussing on NaOH-based system here ease comparison with other systems. has been used decades field; however, new still being explored even to this day identify chemical(s) dissolving it. Chitin, due biocompatibility, allows us use it multifaceted purposes. Hence, important consolidate available studies better about sought-after biomaterial. This overview deeply delves into action existing highlights merits demerits. It discusses rheological properties gel from different puts forth current applications areas tissue engineering, drug delivery, biosensing, hemostasis wound healing. also outlines recent advances potential gaps need addressed future studies.

Language: Английский

Citations

1
Recent advances in near-infrared stimulated nanohybrid hydrogels for cancer photothermal therapy DOI
Yongjun Hu,

Yi Zhou,

Kaichun Li

et al.

Biomaterials Science, Journal Year: 2024, Volume and Issue: 12(18), P. 4590 - 4606

Published: Jan. 1, 2024

Nanomedicine has emerged as a promising avenue for advancing cancer treatment, but the challenge of mitigating its in vivo side effects necessitates development innovative structures and materials. Recent investigation unveiled nanogels particularly compelling candidates, characterized by porous, three-dimensional network architecture that exhibits exceptional drug loading capacity. Beyond this, boast substantial specific surface area can be tailored with chemical functionalities. Consequently, are frequently engineered multi-modal synergistic platform combating cancer, wherein photothermal therapy stands out due to capacity penetrate deep tissues achieve localized tumor eradication through application elevated temperatures. In this review, we delve into synthesis diverse varieties capable controlled release triggered either or physical stimuli. It also summarizes their potential integration alongside other therapeutic modalities realize effective ablation. Moreover, analyze primary mechanisms underlying contribution treatment while underscoring adeptness regulating temperatures repairing bone defects resulting from tumor-associated trauma. Envisioned an auspicious strategy realm therapy, hold promise furnishing delivery precise thermal ablation capabilities.

Language: Английский

Citations

1