Revolutionizing biocatalysis: A review on innovative design and applications of enzyme-immobilized microfluidic devices DOI
Pravin D. Patil,

Niharika Gargate,

Khushi Dongarsane

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 136193 - 136193

Published: Oct. 1, 2024

Language: Английский

Emerging bio-dispersant and bioremediation technologies as environmentally friendly management responses toward marine oil spill: A comprehensive review DOI
Emmanuel Sunday Okeke, Charles Obinwanne Okoye, Timothy Prince Chidike Ezeorba

et al.

Journal of Environmental Management, Journal Year: 2022, Volume and Issue: 322, P. 116123 - 116123

Published: Sept. 2, 2022

Language: Английский

Citations

79

Acetylcholinesterase biosensors for electrochemical detection of neurotoxic pesticides and acetylcholine neurotransmitter: A literature review DOI
Vahulabaranan Rajagopalan,

Swethaa Venkataraman,

Devi Sri Rajendran

et al.

Environmental Research, Journal Year: 2023, Volume and Issue: 227, P. 115724 - 115724

Published: March 21, 2023

Language: Английский

Citations

57

Cellulase immobilization to enhance enzymatic hydrolysis of lignocellulosic biomass: An all-inclusive review DOI
Chaozhong Xu,

Shanshan Tong,

Liqun Sun

et al.

Carbohydrate Polymers, Journal Year: 2023, Volume and Issue: 321, P. 121319 - 121319

Published: Aug. 22, 2023

Language: Английский

Citations

56

Exploring Emergent Properties in Enzymatic Reaction Networks: Design and Control of Dynamic Functional Systems DOI Creative Commons
Souvik Ghosh, Mathieu G. Baltussen, Nikita M. Ivanov

et al.

Chemical Reviews, Journal Year: 2024, Volume and Issue: 124(5), P. 2553 - 2582

Published: March 4, 2024

The intricate and complex features of enzymatic reaction networks (ERNs) play a key role in the emergence sustenance life. Constructing such vitro enables stepwise build up complexity introduces opportunity to control activity using physicochemical stimuli. Rational design modulation network motifs enable engineering artificial systems with emergent functionalities. Such functional are useful for variety reasons as creating new-to-nature dynamic materials, producing value-added chemicals, constructing metabolic modules synthetic cells, even enabling molecular computation. In this review, we offer insights into chemical characteristics ERNs while also delving their potential applications associated challenges.

Language: Английский

Citations

26

A Comprehensive Guide to Enzyme Immobilization: All You Need to Know DOI Creative Commons
Marina Simona Robescu, Teodora Bavaro

Molecules, Journal Year: 2025, Volume and Issue: 30(4), P. 939 - 939

Published: Feb. 18, 2025

Enzyme immobilization plays a critical role in enhancing the efficiency and sustainability of biocatalysis, addressing key challenges such as limited enzyme stability, short shelf life, difficulties recovery recycling, which are pivotal for green chemistry industrial applications. Classical approaches, including adsorption, entrapment, encapsulation, covalent bonding, well advanced site-specific methods that integrate engineering bio-orthogonal chemistry, were discussed. These techniques enable precise control over orientation interaction with carriers, optimizing catalytic activity reusability. Key findings highlight impact on improving performance under various operational conditions its reducing process costs through enhanced stability recyclability. The review presents numerous practical applications immobilized enzymes, their use pharmaceutical industry drug synthesis, food sector dairy processing, environmental biotechnology wastewater treatment dye degradation. Despite significant advantages, loss due to conformational changes mass transfer limitations remain, necessitating tailored protocols specific integration modern biotechnological advancements, site-directed mutagenesis recombinant DNA technology, offers promising pathway developing robust, efficient, sustainable biocatalytic systems. This comprehensive guide aims support researchers industries selecting diverse pharmaceuticals, fine chemicals.

Language: Английский

Citations

7

Microbial-Based Heavy Metal Bioremediation: Toxicity and Eco-Friendly Approaches to Heavy Metal Decontamination DOI Creative Commons
Biao Zhou,

Tiejian Zhang,

Fei Wang

et al.

Applied Sciences, Journal Year: 2023, Volume and Issue: 13(14), P. 8439 - 8439

Published: July 21, 2023

There are several industrial processes in which heavy metals used, including but not limited to chrome plating and tanning. Amongst the most toxic human health arsenic, cadmium, chromium, lead, copper, nickel, mercury. The aforementioned possess ability cause contamination upon their release into environment. Humans aquatic terrestrial animals at risk from water soil. Heavy metal toxicity has potential result complications, such as renal hepatic impairment, dermatological afflictions, cognitive lethargy, potentially oncogenic manifestations. removal of wastewater soil can be accomplished using a variety conventional methods, membrane filtration, reverse osmosis, chemical reduction, adsorption. These methods have disadvantages, generating an abundance secondary pollutants, entail significantly higher costs comparison biological methods. Conversely, eco-friendly techniques based on microbes numerous advantages. This review provides comprehensive overview that remove ions, both metabolically dependent independent. Additionally, we also focused source these metals. study is expected particularly beneficial for development treatment systems water.

Language: Английский

Citations

39

Smart chemistry and applied perceptions of enzyme-coupled nano-engineered assemblies to meet future biocatalytic challenges DOI
Ayesha Anwar, Muhammad Imran, Hafiz M.N. Iqbal

et al.

Coordination Chemistry Reviews, Journal Year: 2023, Volume and Issue: 493, P. 215329 - 215329

Published: July 9, 2023

Language: Английский

Citations

28

Enhancing Lipase Immobilization via Physical Adsorption: Advancements in Stability, Reusability, and Industrial Applications for Sustainable Biotechnological Processes DOI Creative Commons

Cinthia Silva Almeida,

Francisco Simão Neto, Patrick da Silva Sousa

et al.

ACS Omega, Journal Year: 2024, Volume and Issue: 9(47), P. 46698 - 46732

Published: Nov. 14, 2024

Immobilization of lipases by physical adsorption improves their stability, recovery, and reusability in biotechnological processes. The present review provides an advanced bibliometric analysis a comprehensive overview research progress this field. By searching Web Science, 39,575 publications were analyzed, 325 relevant articles selected. Key journals, countries, institutions, authors identified. most cited focus on biofuel production industrial applications. revealed four themes with the biofuel. method is effective when appropriate support used. Despite decrease patent applications, interest remains high. Future studies should optimizing materials exploring new applications technique. detailed understanding immobilization adsorption.

Language: Английский

Citations

16

Efficient and feasible biocatalysts: Strategies for enzyme improvement. A review DOI
Samah Hashim Albayati,

Nima Ghahremani Nezhad,

Abdulrahman M Taki

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 276, P. 133978 - 133978

Published: July 20, 2024

Language: Английский

Citations

12

Integration of microfluidic chips with biosensors DOI Creative Commons

Masindi Sekhwama,

Kelvin Mpofu,

Sivarasu Sudesh

et al.

Deleted Journal, Journal Year: 2024, Volume and Issue: 6(9)

Published: Aug. 23, 2024

Abstract The potential threat posed by disease outbreaks to diagnostic instruments demands the development of more effective biosensor technologies counteract risks. Diseases like SARS-CoV-2, Ebola, malaria, cholera, and many have demonstrated beyond limits health care that new advancements are required for early detection diagnosis. rising number diseases has led an increasing demand biosensors quicker utilize in healthcare settings. A incorporated with microfluidic chips offers improved compared traditional or classical biosensors. Microfluidic improve performance allowing automation, mixing, separation, throughput processing, transport analytes desired reactors. a chip sensitivity, easy operation can use small volumes samples process results. effectiveness depends also on materials used its fabrication there which reviewed this work. This paper reviews advantages enhance biosensors, fabricate chips, electrodes into time shortening processing at point service. work not previously addressed other including, integration cell-imprinted polymers sensors delved future outlook.

Language: Английский

Citations

12