Visible-Light Active Titanium Dioxide Nanomaterials with Bactericidal Properties

Nanomaterials, Journal Year: 2020, Volume and Issue: 10(1), P. 124 - 124

Published: Jan. 9, 2020

This article provides an overview of current research into the development, synthesis, photocatalytic bacterial activity, biocompatibility and cytotoxic properties various visible-light active titanium dioxide (TiO

Language: Английский

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Recent Advances and Mechanistic Insights into Antibacterial Activity, Antibiofilm Activity, and Cytotoxicity of Silver Nanoparticles

ACS Applied Bio Materials, Journal Year: 2022, Volume and Issue: 5(4), P. 1391 - 1463

Published: March 31, 2022

The substantial increase in multidrug-resistant (MDR) pathogenic bacteria is a major threat to global health. Recently, the Centers for Disease Control and Prevention reported possibilities of greater deaths due bacterial infections than cancer. Nanomaterials, especially small-sized (size ≤10 nm) silver nanoparticles (AgNPs), can be employed combat these deadly diseases. However, high reactivity, instability, susceptibility fast oxidation, cytotoxicity remain crucial shortcomings their uptake clinical application. In this review, we discuss various AgNPs-based approaches eradicate provide comprehensive mechanistic insights recent advances antibacterial activity, antibiofilm (both vitro vivo) AgNPs. antimicrobial activity involves four steps: (i) adhesion AgNPs cell wall/membrane its disruption; (ii) intracellular penetration damage; (iii) oxidative stress; (iv) modulation signal transduction pathways. Numerous factors affecting bactericidal such as shape, size, crystallinity, pH, surface coating/charge have also been described detail. review sheds light on photodynamic therapy role versus Ag+ ions release activities. addition, different methods synthesis discussed brief.

Language: Английский

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Effects of nano- and microplastics on kidney: Physicochemical properties, bioaccumulation, oxidative stress and immunoreaction

Chemosphere, Journal Year: 2021, Volume and Issue: 288, P. 132631 - 132631

Published: Oct. 21, 2021

Language: Английский

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Nano Silver-Induced Toxicity and Associated Mechanisms

International Journal of Nanomedicine, Journal Year: 2022, Volume and Issue: Volume 17, P. 1851 - 1864

Published: April 1, 2022

Abstract: Nano silver is one of the most widely used engineering nanomaterials with antimicrobial activity against bacteria, fungi, and viruses. However, widespread application nano preparations in daily life raises concerns about public health. Although several review articles have described toxicity to specific major organs, an updated comprehensive that clearly systematically outlines harmful effects lacking. This begins routes exposure its distribution vivo. The toxic reactions are then discussed on three levels, from organ cellular subcellular levels. also provides new insights adjusting by changing their size surface functionalization combination other materials form a composite formulation. Finally, future development, challenges, research directions discussed. Graphical Keywords: silver, routes, distribution, toxicity, mechanism

Language: Английский

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Drug Delivery Systems in Regenerative Medicine: An Updated Review

Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(2), P. 695 - 695

Published: Feb. 18, 2023

Modern drug discovery methods led to evolving new agents with significant therapeutic potential. However, their properties, such as solubility and administration-related challenges, may hinder benefits. Moreover, advances in biotechnology resulted the development of a generation molecules short half-life that necessitates frequent administration. In this context, controlled release systems are required enhance treatment efficacy improve patient compliance. Innovative delivery promising tools protect proteins peptides against proteolytic degradation where is achievable. The present review provides an overview different approaches used for delivery.

Language: Английский

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Review on fate, transport, toxicity and health risk of nanoparticles in natural ecosystems: Emerging challenges in the modern age and solutions toward a sustainable environment

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 912, P. 169331 - 169331

Published: Dec. 15, 2023

Language: Английский

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Nanomaterials: a review of emerging contaminants with potential health or environmental impact

Discover Nano, Journal Year: 2023, Volume and Issue: 18(1)

Published: April 21, 2023

Abstract Nanotechnologies have been advantageous in many sectors and gaining much concern due to the unique physical, chemical biological properties of nanomaterials (NMs). We surveyed peer-reviewed publications related “nanotechnology”, “NMs”, “NMs water treatment”, air environmental risk” last 23 years. found that most research work is focused on developing novel applications for NMs new products with peculiar features. In contrast, there are relatively few concerning as contaminants relative applications. Thus, we devoted this review emerging contaminants. The definition classification will be presented first demonstrate importance unifying definition. information provided here should facilitate detection, control, regulation environment. high surface-area-to-volume ratio reactivity cause prediction potential toxicities NPs extremely difficult; therefore, marked knowledge gaps fate, impact, toxicity, risk NMs. Consequently, modifying extraction methods, detection tools, characterization technologies essential complete assessment This help also setting regulations standards releasing handling no specific regulations. Finally, integrated treatment necessary removal water. Also, membrane technology recommended remediation air.

Language: Английский

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Mode of Action of Biogenic Silver, Zinc, Copper, Titanium and Cobalt Nanoparticles Against Antibiotics Resistant Pathogens

Journal of Inorganic and Organometallic Polymers and Materials, Journal Year: 2024, Volume and Issue: 34(4), P. 1417 - 1451

Published: Jan. 9, 2024

Language: Английский

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Metal–Drug Coordination Nanoparticles and Hydrogels for Enhanced Delivery

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(26)

Published: April 11, 2024

Drug delivery is a key component of nanomedicine, and conventional relies on the adsorption or encapsulation drug molecules to nanomaterial. Many vehicles contain metal ions, such as metal-organic frameworks, oxides, transition dichalcogenides, MXene, noble nanoparticles. These materials have high content pose potential long-term toxicity concerns leading difficulties for clinical approval. In this review, recent developments are summarized in use ligands coordination forming various nanomaterials soft materials. these cases, drug-to-metal ratio much higher than adsorption-based strategies. The divided into small-molecule drugs, nucleic acids, proteins. formed hybrid mainly include nanoparticles hydrogels, upon which targeting can be grafted improve efficacy further decrease toxicity. application addressing cancer, viral infection, bacterial infection inflammatory bowel disease, bone diseases reviewed. end, some future directions discussed from fundamental research, science, medicine.

Language: Английский

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Nanoparticles in Soil Reclamation: A Review of Their Role in Reducing Soil Compaction

Air Soil and Water Research, Journal Year: 2025, Volume and Issue: 18

Published: Jan. 1, 2025

Rapid population growth and increased use of agricultural technology have exacerbated agrarian problems. While mechanization has improved production, the heavy machinery for planting, irrigation, harvesting resulted in soil compaction. Soil compaction reduces pore space increases bulk density, which hinders plant growth. Globally, automated agriculture reduced crop production by more than 50%. In developing countries, grazing animals fields root penetration, nutrient absorption, water infiltration, increasing risk erosion runoff. The study investigates novel ways to reduce compaction, namely utilization nanoparticles (NPs) nanotechnology (NT). NPs unique qualities that can improve mechanical properties soil, increase its strength, minimize Some such as Carbon nanotubes, nanolites, nanosilica, nanoclay been demonstrated fertility, retention, structural stability. environmental pollutants while improving quality. However, questions about their long-term biodegradability, ecological toxicity, health effects require further investigation. also addressed how affect environment human health. Their small size raises concerns potential exposure toxicity individuals ecosystems. paper briefly discusses economic regulatory considerations related use, disposal NPs, emphasizing need comprehensive legislation, impact studies, stakeholder involvement decision-making. Although offer promise sustainable practices, research is necessary optimize ensure safety, well gain a better understanding interactions with physics.

Language: Английский

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