Resistomes from oxytetracycline-treated pigs are readily transferred to untreated pen mates DOI Creative Commons
Katrine Wegener Tams, Anders Rhod Larsen, Karl Pedersen

et al.

Animal Microbiome, Journal Year: 2024, Volume and Issue: 6(1)

Published: Nov. 22, 2024

Pork is currently a major part of Danish food export and also key dietary source protein across the world. Industrial pork production, however, comes with high antibiotic usage in many countries, including Denmark. This has created consumer demand for meat Raised Without Antibiotics (RWA). Previous work demonstrated that levels resistance genes (ARGs) are indeed increased antibiotically treated animals, but suggest these ARGs transferred to untreated pen-mates. In commercial farm, we studied four groups physically separated pigs: one group only pigs (n = 20), 30 total, n 15 analysed), combining 15) 15). These were followed 16 weeks during which all profiled both their faecal microbiome (through S rRNA gene sequencing) resistome (by use high-throughput qPCR platform targeting 82 variants). We found was substantially enriched compared but, importantly, observed co-reared had approaching pen mates, suggesting enterotype readily animal. From this, conclude mixing causes spill-over resistant bacteria and/or from when co-reared. To optimize RWA should be limit proliferation ARGs.

Language: Английский

Potential Causes of Spread of Antimicrobial Resistance and Preventive Measures in One Health Perspective-A Review DOI Creative Commons
Habtamu Endale, Mesfin Mathewos,

Debela Abdeta

et al.

Infection and Drug Resistance, Journal Year: 2023, Volume and Issue: Volume 16, P. 7515 - 7545

Published: Dec. 1, 2023

Abstract: Antimicrobial resistance, referring to microorganisms' capability subsist and proliferate even when there are antimicrobials is a foremost threat public health globally. The appearance of antimicrobial resistance can be ascribed anthropological, animal, environmental factors. Human-related causes include overuse misuse in medicine, antibiotic-containing cosmetics biocides utilization, inadequate sanitation hygiene settings. Prophylactic therapeutic overuse, using as feed additives, microbes resistant antibiotics genes animal excreta, residue found animal-origin food excreta animals related contributive factors for the antibiotic emergence spread. Environmental including naturally existing genes, improper disposal unused antimicrobials, contamination from waste settings, farms, pharmaceutical industries, use agricultural chemicals facilitatet its Wildlife has plausible role Adopting one-health approach involving properly humans, improving spaces implementing coordinated governmental regulations crucial combating resistance. Collaborative cooperative involvement stakeholders public, veterinary ecological sectors circumvent problem effectively. Keywords: one health, gene, environment, wildlife

Language: Английский

Citations

69
An Overview of the Recent Advances in Antimicrobial Resistance DOI Creative Commons
Manuela Oliveira, Wilson Antunes,

S. R. F. MOTA

et al.

Microorganisms, Journal Year: 2024, Volume and Issue: 12(9), P. 1920 - 1920

Published: Sept. 21, 2024

Antimicrobial resistance (AMR), frequently considered a major global public health threat, requires comprehensive understanding of its emergence, mechanisms, advances, and implications. AMR’s epidemiological landscape is characterized by widespread prevalence constantly evolving patterns, with multidrug-resistant organisms (MDROs) creating new challenges every day. The most common mechanisms underlying AMR (i.e., genetic mutations, horizontal gene transfer, selective pressure) contribute to the emergence dissemination resistant strains. Therefore, mitigation strategies (e.g., antibiotic stewardship programs—ASPs—and infection prevention control strategies—IPCs) emphasize importance responsible antimicrobial use surveillance. A One Health approach interconnectedness human, animal, environmental health) highlights necessity for interdisciplinary collaboration holistic in combating AMR. Advancements novel therapeutics alternative agents vaccines) offer promising avenues addressing challenges. Policy interventions at international national levels also promote ASPs aiming regulate use. Despite all observed progress, remains pressing concern, demanding sustained efforts address emerging threats sustainability. Future research must prioritize innovative approaches complex socioecological dynamics This manuscript resource researchers, policymakers, healthcare professionals seeking navigate develop effective mitigation.

Language: Английский

Citations

29
Efficacy of continuous education and determinants of antimicrobials prescription behavior in companion animal veterinarians from Quebec, Canada DOI
Jean-Philippe Rocheleau,

Cécile Ferrouillet,

Pablo Valdes Donoso

et al.

Preventive Veterinary Medicine, Journal Year: 2025, Volume and Issue: unknown, P. 106515 - 106515

Published: March 1, 2025

Language: Английский

Citations

0
One Health Approach: Antibiotic Resistance Among Enterococcal Isolates in Dairy Farms in Selangor DOI Creative Commons
S. Rajendiran, Yuvaneswary Veloo, Salina Abdul Rahman

et al.

Antibiotics, Journal Year: 2025, Volume and Issue: 14(4), P. 380 - 380

Published: April 4, 2025

Background/Objectives: Antibiotic resistance is a growing public health concern. The One Health approach essential in addressing antibiotic (AR) resistance. Therefore, this study aimed to determine AR among enterococcal isolates dairy farms across various domains based on the emerging industry. Methods: A total of 208 from workers = 70, milk 76, and environment 62 eight Selangor, Malaysia, were used study. bacterial identification susceptibility testing (AST) conducted utilising Vitek-2 system. Results: Approximately 28% exhibited all tested antibiotics. relatively higher proportion demonstrated tetracycline, which was followed by erythromycin. multidrug (MDR) multiple (MAR) index low Conclusions: studied lower AR, MDR, MAR values. Nevertheless, ongoing surveillance due recent expansion farming

Language: Английский

Citations

0
Effect of single parenteral administration of marbofloxacin on bacterial load and selection of resistant Enterobacteriaceae in the fecal microbiota of healthy pigs DOI Creative Commons

Masayoshi Miyauchi,

Farid El Garch,

William Thériault

et al.

BMC Veterinary Research, Journal Year: 2024, Volume and Issue: 20(1)

Published: Oct. 29, 2024

Language: Английский

Citations

2
Food risk assessment in the farm-to-table continuum: report from the conference on good hygiene practices to ensure food safety DOI Creative Commons
Mohamed Rhouma, Marie‐Lou Gaucher, Badredine Souhail

et al.

Agriculture & Food Security, Journal Year: 2024, Volume and Issue: 13(1)

Published: May 21, 2024

Abstract Foodborne diseases (FBDs) are a major worldwide public health concern. In the current context of globalization, it has become crucial to establish effective collaboration between countries reduce incidence FBDs, by creating knowledge-sharing activities address this challenge. However, despite importance subject, there limited opportunities for researchers from French-speaking meet and exchange expertise in field. Researchers Faculty Veterinary Medicine Université de Montréal (Canada) Science, University Abdelmalek Essaadi (Morocco) took initiative organize first edition conference on Good Hygiene Practices Ensure Food Safety , that was held virtually May 25 26, 2022. Attendees ( n = 122) came academic, food processing government sectors. The great opportunity showcase practical application risk analysis paradigm, with concrete examples hazards, as well use latest high-throughput sequencing technologies tool source attribution molecular typing some most important foodborne pathogens. addition, created valuable forum knowledge international safety experts, particularly respect Canadian regulations compared those other countries. Interestingly, following success edition, conference’s scientific committee decided continue organizing event biannual basis, provide unique learn about advances safety.

Language: Английский

Citations

1
Cross‐Correlation between Biosecurity Measures and the Detection of Viral and Bacterial Agents on German Farms with Respiratory Disease DOI Creative Commons
Julia Stadler,

Kathrin Lillie-Jaschniski,

Sophia Zwickl

et al.

Transboundary and Emerging Diseases, Journal Year: 2024, Volume and Issue: 2024(1)

Published: Jan. 1, 2024

Effective porcine health management relies majorly on diagnostic tests, vaccination, treatment strategies, and a proper biosecurity plan. However, understanding the link between circulating microbes measures pig farm is not evident. Substantial progress has been made in recent years with availability of new tools (e.g., sequencing‐based diagnostics) extensive questionnaires. interpretation correlation these results are hampered by abundance gained (meta)data. Therefore, we aimed to cross‐correlate viral bacterial pathogens respiratory tropism detected third‐generation nanopore metagenomic sequencing assessed Biocheck.UGent™. The study was conducted 25 sow farms attached nurseries Germany known distress. level complied European averages. Interestingly, highest score showed lowest overall prevalence reproductive syndrome virus (PRRSV) Actinobacillus sp.; circulation well‐studied pathogenic viruses, such as PRRSV, correlated lower scores, higher number stillborn piglets, cocirculation parvovirus type 7. Moreover, potential risk factors for lesser‐known agents hemagglutinating encephalomyelitis virus, coronavirus, polyomavirus) could also be addressed. For pathogen Glaesserella sp., increased clinical signs observed, whereas Lactobacillus sp. Moraxella putative biomarkers better scores. In conclusion, in‐depth cross‐correlation (meta)data from platforms may contribute actions adapting measures. This will only improved animal welfare economic productivity but helping address (new) zoonotic disease threats treatments.

Language: Английский

Citations

1
Nanomaterials as signal amplifiers in CRISPR/Cas biosensors: A path toward multiplex point-of-care diagnostics DOI
Fareeha Arshad,

Bong Jing Yee,

Koo Pey Ting

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: 207, P. 111826 - 111826

Published: Oct. 2, 2024

Language: Английский

Citations

1
Metagenomic insights into plasmid-mediated antimicrobial resistance in poultry slaughterhouse wastewater: antibiotics occurrence and genetic markers DOI
Beatriz Oliveira de Farias, Enrico Mendes Saggioro,

Kaylanne S. Montenegro

et al.

Environmental Science and Pollution Research, Journal Year: 2024, Volume and Issue: 31(51), P. 60880 - 60894

Published: Oct. 12, 2024

Language: Английский

Citations

1
Characterization of four digestates from different types of substrates used in biogas production in Northern Peru DOI Creative Commons
Jesús Rascón, Lily Juarez-Contreras,

Euler Willan García Saldaña

et al.

F1000Research, Journal Year: 2024, Volume and Issue: 13, P. 24 - 24

Published: Jan. 8, 2024

Background Biol is one of the best-known digestates, which occurs during anaerobic digestion in biodigesters to generate biogas, using animal manure and vegetable waste. This digestate type used organic agriculture due its easy application, contributing simultaneously circular economy food security. Methods The objective this study was characterize four types biol, generated for biogas production implemented northern Peru fed with manure: i) pig manure; ii) cattle iii) horse iv) coffee processing water. All had same design but worked under different environmental conditions. Descriptive multivalent statistics were applied data obtained parameters evaluated. Results biols nutritional compositions, depending on substrate used. biol from characterized by high concentrations bacteria, low nutrients general, rich salts, water matter. Conclusions These results showed that all can be agriculture. However, their selection will depend requirements crop soil where are applied.

Language: Английский

Citations

0